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The map label for this gene is kdpA

Identifier: 16120120

GI number: 16120120

Start: 147474

End: 149222

Strand: Direct

Name: kdpA

Synonym: VNG6176G

Alternate gene names: 16120120

Gene position: 147474-149222 (Clockwise)

Preceding gene: 16120118

Following gene: 16120121

Centisome position: 40.36

GC content: 60.15

Gene sequence:

>1749_bases
ATGGCGAGTCCACCACCAATCGTCGAGTACGCGGTGTTCTTCACCATCCTTGCCGTCCTCGTTTTCGTGGCCGGCGAGTA
CCTCGCGTGGGTGTACCGCGAACAGGCGAACAGCGACCATCGACCACCGGGTTACTTGTCCTGGTTCGAACGATTAGACG
AGATATTCACACCCATCGAGAACGGCTTATATCGCCTGTCCGGAATTAATCCGAGACGGGAGATGACCTGGAAAGGGTAC
CTAAAGGCGGTACTCGTGTTTAACGTGTGTATCTGGGTGTTGTTGTTCGTTGTGTTGATGTTCCAGGATGCCCTCCCGAT
GAACTTCGTCGGAGTTGGCGGTGAGAGCTGGGACCTCGCATTCCACACCGCGAGTTCGTTCACCTCGAACACGAACCAGC
AACACTACAGCGGTGAGACCCTCTCGGTGTTCACCCACACGTTCGGTATCGGAATCGCGATGTTCTTGACGCCCGCGACC
GGGCTGGCACTCATGCCTGCGTTCGCCCGTGCGTTCACGAACAAAGAGGACCCGCGGCTCGGGAACTTCTACGAGAACGT
CGTTCGGGGGCTCGTTCGGTTCCTCCTCCCGATCTCGCTGCTCATCGCGATCATCCTGATGGCTGAGGGATCCGTCCAGA
CGATTCTGGGAGGCCAACTCACTGCAAACACGTTCACGATGGGCATCCAGAACATCCGCATCGGCCCCCATGCGGGGATC
GAGGCGATCAAGATGTTCGGAACGAACGGCGGTGGGATCAACGCTGCGAACGCGGCGACAGCGTTCGAGAACCCTACCCC
CCTGAGTAACCTCGTCCTGACGCTGGCGATGCCGATCGGCACGTTCAGCGCAATCTACGCGTGGGGCGCGTGGGTCGGCA
ATCGAAGCCACGGAGTCGCAATCGTGGCCGCGTTCTTCGTCATCTACATGGCTCTCACTGGTGTCGCGGTCGTCGGTGAG
ACCGGCACGAACGCCGGCATGGTGGTTACTGGAAATGGCCTGCACGTCGACCAGACCGTTGGGAACATGGAGGGCAAGGA
GACACGCTTCGGACCGACGGCCAGTGCGATCTGGGGGCTGTCGACCACGGGTACGACGAATGGGGGTGTCAACAGCATGC
ACAACAGCTGGACCGCACTCGGTGCGTTCTCCTTGCTGTTCGCGTTCGCCACCAACAACATCAGTAACGGTGTTGGCACG
GGGCTGTTGAACATCCTGATGTTCGTCATCCTCACTGCCTTCATCGGCGCGCTGATGATCGGCCGCCGCCCGCAGTACCT
CGGGAAGAAGCTCGAGTGGCAGGAGATGCGGTACGTCTTCGTCGTTATCCTCGTACTCCCGATACTGGTACTGATCCCGC
AGGCAGCGGCCGTCGTGTACCAGGGCGCGATCGATTCGATGAACAACCCCGGGTTCCGCGGGTTCTCCGAGGTGCTCTAC
GAGTTCTTCTCGGCATCCGCGAACAACGGGAGCGGGTTCGAGGGGCTCGGCGACGGGACGCTGTTTTTCAACCTCGTCAA
CGGCGTCCAGGTGCTCCTGGCCCGGTACGTTCCGATCACAGCACAGCTCGCGATCGCCGGCTATCTCGCCAACAAGAAGG
TGAGCCCCGAATCAAAGGGGTCTCTCGACACTGACACGCCGGCGTTTGTTGGACTCCTGATCGGTGTCATCATCATCGTT
AGCGCGCTGGTGTTCCTGCCGGCGCTGGTGTTCGGCCCGATCGGTGAACTACTGAGCGGAGGGATCTGA

Upstream 100 bases:

>100_bases
AGTTGCACATGCTAATCGGCGAAGCGGTACTGGCAGTAGTGACTGTAGCGGTCGTGGCGTACCTGACGTACGTCATGATG
TACCCAACGAGGTTCTAACA

Downstream 100 bases:

>100_bases
CATGGCAGAGATCACAGTCACAATAGACACGGACCAACAGAAGCAGGCGATCAGCGATTCGTTCGCCAAGCTGGACCCGC
AGTACCTGGTTAAGAACCCG

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MASPPPIVEYAVFFTILAVLVFVAGEYLAWVYREQANSDHRPPGYLSWFERLDEIFTPIENGLYRLSGINPRREMTWKGY
LKAVLVFNVCIWVLLFVVLMFQDALPMNFVGVGGESWDLAFHTASSFTSNTNQQHYSGETLSVFTHTFGIGIAMFLTPAT
GLALMPAFARAFTNKEDPRLGNFYENVVRGLVRFLLPISLLIAIILMAEGSVQTILGGQLTANTFTMGIQNIRIGPHAGI
EAIKMFGTNGGGINAANAATAFENPTPLSNLVLTLAMPIGTFSAIYAWGAWVGNRSHGVAIVAAFFVIYMALTGVAVVGE
TGTNAGMVVTGNGLHVDQTVGNMEGKETRFGPTASAIWGLSTTGTTNGGVNSMHNSWTALGAFSLLFAFATNNISNGVGT
GLLNILMFVILTAFIGALMIGRRPQYLGKKLEWQEMRYVFVVILVLPILVLIPQAAAVVYQGAIDSMNNPGFRGFSEVLY
EFFSASANNGSGFEGLGDGTLFFNLVNGVQVLLARYVPITAQLAIAGYLANKKVSPESKGSLDTDTPAFVGLLIGVIIIV
SALVFLPALVFGPIGELLSGGI

Sequences:

>Translated_582_residues
MASPPPIVEYAVFFTILAVLVFVAGEYLAWVYREQANSDHRPPGYLSWFERLDEIFTPIENGLYRLSGINPRREMTWKGY
LKAVLVFNVCIWVLLFVVLMFQDALPMNFVGVGGESWDLAFHTASSFTSNTNQQHYSGETLSVFTHTFGIGIAMFLTPAT
GLALMPAFARAFTNKEDPRLGNFYENVVRGLVRFLLPISLLIAIILMAEGSVQTILGGQLTANTFTMGIQNIRIGPHAGI
EAIKMFGTNGGGINAANAATAFENPTPLSNLVLTLAMPIGTFSAIYAWGAWVGNRSHGVAIVAAFFVIYMALTGVAVVGE
TGTNAGMVVTGNGLHVDQTVGNMEGKETRFGPTASAIWGLSTTGTTNGGVNSMHNSWTALGAFSLLFAFATNNISNGVGT
GLLNILMFVILTAFIGALMIGRRPQYLGKKLEWQEMRYVFVVILVLPILVLIPQAAAVVYQGAIDSMNNPGFRGFSEVLY
EFFSASANNGSGFEGLGDGTLFFNLVNGVQVLLARYVPITAQLAIAGYLANKKVSPESKGSLDTDTPAFVGLLIGVIIIV
SALVFLPALVFGPIGELLSGGI
>Mature_581_residues
ASPPPIVEYAVFFTILAVLVFVAGEYLAWVYREQANSDHRPPGYLSWFERLDEIFTPIENGLYRLSGINPRREMTWKGYL
KAVLVFNVCIWVLLFVVLMFQDALPMNFVGVGGESWDLAFHTASSFTSNTNQQHYSGETLSVFTHTFGIGIAMFLTPATG
LALMPAFARAFTNKEDPRLGNFYENVVRGLVRFLLPISLLIAIILMAEGSVQTILGGQLTANTFTMGIQNIRIGPHAGIE
AIKMFGTNGGGINAANAATAFENPTPLSNLVLTLAMPIGTFSAIYAWGAWVGNRSHGVAIVAAFFVIYMALTGVAVVGET
GTNAGMVVTGNGLHVDQTVGNMEGKETRFGPTASAIWGLSTTGTTNGGVNSMHNSWTALGAFSLLFAFATNNISNGVGTG
LLNILMFVILTAFIGALMIGRRPQYLGKKLEWQEMRYVFVVILVLPILVLIPQAAAVVYQGAIDSMNNPGFRGFSEVLYE
FFSASANNGSGFEGLGDGTLFFNLVNGVQVLLARYVPITAQLAIAGYLANKKVSPESKGSLDTDTPAFVGLLIGVIIIVS
ALVFLPALVFGPIGELLSGGI

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=525, Percent_Identity=41.9047619047619, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_HALSA (P57684)

Other databases:

- EMBL:   AE004438
- RefSeq:   NP_395708.1
- GeneID:   1449091
- GenomeReviews:   AE004438_GR
- KEGG:   hal:VNG6176G
- NMPDR:   fig|64091.1.peg.2392
- HOGENOM:   HBG291815
- OMA:   NMHDTLT
- ProtClustDB:   PRK05482
- BioCyc:   HSP64091:VNG6176G-MONOMER
- BRENDA:   3.6.3.12
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 62354; Mature: 62223

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xbdf240c)-; HASH(0xb5dba28)-; HASH(0xbdf279c)-; HASH(0xbff77e4)-; HASH(0xadc504c)-; HASH(0xbff773c)-; HASH(0xb74f568)-; HASH(0xad0c444)-; HASH(0xbdf2484)-; HASH(0xbff78bc)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPPPIVEYAVFFTILAVLVFVAGEYLAWVYREQANSDHRPPGYLSWFERLDEIFTPIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NGLYRLSGINPRREMTWKGYLKAVLVFNVCIWVLLFVVLMFQDALPMNFVGVGGESWDLA
CCCEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEE
FHTASSFTSNTNQQHYSGETLSVFTHTFGIGIAMFLTPATGLALMPAFARAFTNKEDPRL
EEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
GNFYENVVRGLVRFLLPISLLIAIILMAEGSVQTILGGQLTANTFTMGIQNIRIGPHAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEHHHHHHHHHHEECCCCCCH
EAIKMFGTNGGGINAANAATAFENPTPLSNLVLTLAMPIGTFSAIYAWGAWVGNRSHGVA
HHHHEECCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IVAAFFVIYMALTGVAVVGETGTNAGMVVTGNGLHVDQTVGNMEGKETRFGPTASAIWGL
HHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCEEEHHHHCCCCCCCCCCCCCHHHHCCC
STTGTTNGGVNSMHNSWTALGAFSLLFAFATNNISNGVGTGLLNILMFVILTAFIGALMI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GRRPQYLGKKLEWQEMRYVFVVILVLPILVLIPQAAAVVYQGAIDSMNNPGFRGFSEVLY
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
EFFSASANNGSGFEGLGDGTLFFNLVNGVQVLLARYVPITAQLAIAGYLANKKVSPESKG
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
SLDTDTPAFVGLLIGVIIIVSALVFLPALVFGPIGELLSGGI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
ASPPPIVEYAVFFTILAVLVFVAGEYLAWVYREQANSDHRPPGYLSWFERLDEIFTPIE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NGLYRLSGINPRREMTWKGYLKAVLVFNVCIWVLLFVVLMFQDALPMNFVGVGGESWDLA
CCCEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEE
FHTASSFTSNTNQQHYSGETLSVFTHTFGIGIAMFLTPATGLALMPAFARAFTNKEDPRL
EEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
GNFYENVVRGLVRFLLPISLLIAIILMAEGSVQTILGGQLTANTFTMGIQNIRIGPHAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEHHHHHHHHHHEECCCCCCH
EAIKMFGTNGGGINAANAATAFENPTPLSNLVLTLAMPIGTFSAIYAWGAWVGNRSHGVA
HHHHEECCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IVAAFFVIYMALTGVAVVGETGTNAGMVVTGNGLHVDQTVGNMEGKETRFGPTASAIWGL
HHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCEEEHHHHCCCCCCCCCCCCCHHHHCCC
STTGTTNGGVNSMHNSWTALGAFSLLFAFATNNISNGVGTGLLNILMFVILTAFIGALMI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GRRPQYLGKKLEWQEMRYVFVVILVLPILVLIPQAAAVVYQGAIDSMNNPGFRGFSEVLY
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
EFFSASANNGSGFEGLGDGTLFFNLVNGVQVLLARYVPITAQLAIAGYLANKKVSPESKG
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
SLDTDTPAFVGLLIGVIIIVSALVFLPALVFGPIGELLSGGI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11016950