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The map label for this gene is virE2

Identifier: 16119805

GI number: 16119805

Start: 206256

End: 207926

Strand: Direct

Name: virE2

Synonym: Atu6190

Alternate gene names: 16119805

Gene position: 206256-207926 (Clockwise)

Preceding gene: 16119804

Following gene: 16119806

Centisome position: 96.28

GC content: 50.33

Gene sequence:

>1671_bases
ATGGATCCGAAGGCCGAAGGCAATGGTGAAAATATCACTGAGACCGCAGCAGGCAATGTCGAAACTTCTGATTTCGTGAA
TTTGAAGCGCCAGAAGAGGGAGGGCGTAAATTCCACCGGGATGTCCGAAATTGATATGACGGGTAGCCAAGAAACTCCCG
AACACAACATGCACGGAAGCCCGACTCACACGGATGATCTCGGCCCGCGGTTGGATGCGGACATGCTCGATTCTCAGTCA
AGTCATGTTTCTAGCAGCGCTCAAGGCAATCGGTCTGAGGTTGAAAATGAGCTATCCAACTTATTCGCGAAGATGGCTTT
ACCAGGCCATGATCGGCGTACCGACGAGTATATTCTTGTGCGGCAAACCGGACAAGACAAGTTCGCAGGTACTACTAAAT
GTAACCTCGATCATCTGCCCACCAAGGCGGAATTCAATGCGAGCTGCCGGCTCTATAGGGATGGAGTCGGCAACTACTAT
CCCCCGCCCCTCGCATTCGAGAGGATCGATATCCCGGAGCAATTGGCTGCACAATTGCATAACCTGGAGCCAAGAGAACA
GAGTAAACAGTGTTTTCAGTACAAGTTGGAAGTCTGGAATCGCGCTCACGCAGAGATGGGCATCACTGGCACCGACATCT
TCTATCAAACAGACAAGAATATTAAGCTCGACCGAAATTATAAATTGAGGCCTGAGGATAGATATATACAAACAGAGAAA
TACGGGCGCAGAGAAATTCAAAAACGCTATGAGCACCAGTTTCAAGCTGGTTCACTGCTGCCGGATATCTTAATCAAGAC
CCCGCAAAATGATATACATTTCTCGTACAGGTTTGCGGGCGACGCTTACGCTAACAAGCGATTTGAGGAATTCGAACGCG
CAATCAAAACTAAATACGGTAGCGATACCGAGATCAAGCTCAAATCCAAATCTGGGATTATGCATGACTCCAAATATTTG
GAATCATGGGAGCGGGGCAGTGCGGATATCCGTTTCGCAGAGTTCGCCGGCGAGAATCGAGCTCACAACAAGCAGTTTCC
GGCTGCGACTGTGAATATGGGAAGGCAGCCAGATGGCCAGGGAGGGATGACTCGCGATCGCCATGTAAGCGTTGACTACC
TATTGCAAAACCTACCCAACTCCCCTTGGACGCAAGCCTTGAAAGAGGGAAAGTTGTGGGATCGAGTTCAGGTCCTTGCT
CGCGACGGAAACCGTTACATGTCACCTTCAAGACTGGAATATTCCGACCCCGAACACTTTACCCAACTGATGGATCAAGT
TGGTCTGCCCGTGTCGATGGGTCGGCAAAGTCATGCGAATAGTGTCAAGTTTGAGCAGTTTGACAGACAGGCAGCGGTTA
TTGTTGCGGATGGCCCGAACTTACGTGAGGTTCCAGATTTGTCCCCGGAAAAGTTGCAACAACTGTCTCAAAAAGATGTC
CTGATAGCGGATCGCAATGAAAAGGGGCAAAGAACCGGCACTTACACTAATGTTGTGGAATATGAGCGCCTGATGATGAA
ATTACCGAGCGACGCAGCGCAGCTTCTCGCTGAACCGTCCGATAGATATTCACGTGCTTTTGTCCGGCCGGAGCCAGCAT
TGCCCCCCATCAGTGACAGCCGGCGGACTTATGAAAGCCGACCGCGCGGCCCAACCGTAAACAGTCTGTAG

Upstream 100 bases:

>100_bases
GGCTTTACGAGTTTGGATCTCGAAATGATTGAACTGGAGAATTTTGTCCTTCACTGCCCGCTCCCCGAAGAAAACCTAGC
CGGCTAAAAGGAGTTAGACG

Downstream 100 bases:

>100_bases
ATTTCCTGATACCGCGTCAGTGACGAAGCCCTTTAGTTCAAAATATGCATTTGAAAGGATTCAACAATGGTCGACACGAC
GAAGAAGAGTGTCGCGAAGT

Product: type IV secretion system single-stranded DNA binding protein VirE2

Products: NA

Alternate protein names: 63.5 kDa virulence protein

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MDPKAEGNGENITETAAGNVETSDFVNLKRQKREGVNSTGMSEIDMTGSQETPEHNMHGSPTHTDDLGPRLDADMLDSQS
SHVSSSAQGNRSEVENELSNLFAKMALPGHDRRTDEYILVRQTGQDKFAGTTKCNLDHLPTKAEFNASCRLYRDGVGNYY
PPPLAFERIDIPEQLAAQLHNLEPREQSKQCFQYKLEVWNRAHAEMGITGTDIFYQTDKNIKLDRNYKLRPEDRYIQTEK
YGRREIQKRYEHQFQAGSLLPDILIKTPQNDIHFSYRFAGDAYANKRFEEFERAIKTKYGSDTEIKLKSKSGIMHDSKYL
ESWERGSADIRFAEFAGENRAHNKQFPAATVNMGRQPDGQGGMTRDRHVSVDYLLQNLPNSPWTQALKEGKLWDRVQVLA
RDGNRYMSPSRLEYSDPEHFTQLMDQVGLPVSMGRQSHANSVKFEQFDRQAAVIVADGPNLREVPDLSPEKLQQLSQKDV
LIADRNEKGQRTGTYTNVVEYERLMMKLPSDAAQLLAEPSDRYSRAFVRPEPALPPISDSRRTYESRPRGPTVNSL

Sequences:

>Translated_556_residues
MDPKAEGNGENITETAAGNVETSDFVNLKRQKREGVNSTGMSEIDMTGSQETPEHNMHGSPTHTDDLGPRLDADMLDSQS
SHVSSSAQGNRSEVENELSNLFAKMALPGHDRRTDEYILVRQTGQDKFAGTTKCNLDHLPTKAEFNASCRLYRDGVGNYY
PPPLAFERIDIPEQLAAQLHNLEPREQSKQCFQYKLEVWNRAHAEMGITGTDIFYQTDKNIKLDRNYKLRPEDRYIQTEK
YGRREIQKRYEHQFQAGSLLPDILIKTPQNDIHFSYRFAGDAYANKRFEEFERAIKTKYGSDTEIKLKSKSGIMHDSKYL
ESWERGSADIRFAEFAGENRAHNKQFPAATVNMGRQPDGQGGMTRDRHVSVDYLLQNLPNSPWTQALKEGKLWDRVQVLA
RDGNRYMSPSRLEYSDPEHFTQLMDQVGLPVSMGRQSHANSVKFEQFDRQAAVIVADGPNLREVPDLSPEKLQQLSQKDV
LIADRNEKGQRTGTYTNVVEYERLMMKLPSDAAQLLAEPSDRYSRAFVRPEPALPPISDSRRTYESRPRGPTVNSL
>Mature_556_residues
MDPKAEGNGENITETAAGNVETSDFVNLKRQKREGVNSTGMSEIDMTGSQETPEHNMHGSPTHTDDLGPRLDADMLDSQS
SHVSSSAQGNRSEVENELSNLFAKMALPGHDRRTDEYILVRQTGQDKFAGTTKCNLDHLPTKAEFNASCRLYRDGVGNYY
PPPLAFERIDIPEQLAAQLHNLEPREQSKQCFQYKLEVWNRAHAEMGITGTDIFYQTDKNIKLDRNYKLRPEDRYIQTEK
YGRREIQKRYEHQFQAGSLLPDILIKTPQNDIHFSYRFAGDAYANKRFEEFERAIKTKYGSDTEIKLKSKSGIMHDSKYL
ESWERGSADIRFAEFAGENRAHNKQFPAATVNMGRQPDGQGGMTRDRHVSVDYLLQNLPNSPWTQALKEGKLWDRVQVLA
RDGNRYMSPSRLEYSDPEHFTQLMDQVGLPVSMGRQSHANSVKFEQFDRQAAVIVADGPNLREVPDLSPEKLQQLSQKDV
LIADRNEKGQRTGTYTNVVEYERLMMKLPSDAAQLLAEPSDRYSRAFVRPEPALPPISDSRRTYESRPRGPTVNSL

Specific function: Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T- DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence composition

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=In infected cells, it is found in the nucleus

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VIRE2_AGRT5 (P08062)

Other databases:

- EMBL:   M15814
- EMBL:   J03320
- EMBL:   AE007871
- PIR:   A26939
- PIR:   AD3251
- RefSeq:   NP_396510.1
- PDB:   3BTP
- PDBsum:   3BTP
- ProteinModelPortal:   P08062
- SMR:   P08062
- DIP:   DIP-46168N
- STRING:   P08062
- GeneID:   1137513
- GenomeReviews:   AE007871_GR
- KEGG:   atu:Atu6190
- eggNOG:   NOG148945
- HOGENOM:   HBG301727
- OMA:   YLESWER
- ProtClustDB:   PRK13868
- BioCyc:   ATUM176299-1:ATU6190-MONOMER
- GO:   GO:0009405
- InterPro:   IPR009868

Pfam domain/function: PF07229 VirE2

EC number: NA

Molecular weight: Translated: 63345; Mature: 63345

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPKAEGNGENITETAAGNVETSDFVNLKRQKREGVNSTGMSEIDMTGSQETPEHNMHGS
CCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCC
PTHTDDLGPRLDADMLDSQSSHVSSSAQGNRSEVENELSNLFAKMALPGHDRRTDEYILV
CCCCCCCCCCCCHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
RQTGQDKFAGTTKCNLDHLPTKAEFNASCRLYRDGVGNYYPPPLAFERIDIPEQLAAQLH
EECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEECCCCHHHHHHHHH
NLEPREQSKQCFQYKLEVWNRAHAEMGITGTDIFYQTDKNIKLDRNYKLRPEDRYIQTEK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCCCCEECHHH
YGRREIQKRYEHQFQAGSLLPDILIKTPQNDIHFSYRFAGDAYANKRFEEFERAIKTKYG
HHHHHHHHHHHHHHHCCCCCCHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCC
SDTEIKLKSKSGIMHDSKYLESWERGSADIRFAEFAGENRAHNKQFPAATVNMGRQPDGQ
CCCEEEEECCCCCCCCHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCHHHCCCCCCCCC
GGMTRDRHVSVDYLLQNLPNSPWTQALKEGKLWDRVQVLARDGNRYMSPSRLEYSDPEHF
CCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
TQLMDQVGLPVSMGRQSHANSVKFEQFDRQAAVIVADGPNLREVPDLSPEKLQQLSQKDV
HHHHHHHCCCHHCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCE
LIADRNEKGQRTGTYTNVVEYERLMMKLPSDAAQLLAEPSDRYSRAFVRPEPALPPISDS
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHCCCCCCCCCCCCCCC
RRTYESRPRGPTVNSL
CHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDPKAEGNGENITETAAGNVETSDFVNLKRQKREGVNSTGMSEIDMTGSQETPEHNMHGS
CCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCC
PTHTDDLGPRLDADMLDSQSSHVSSSAQGNRSEVENELSNLFAKMALPGHDRRTDEYILV
CCCCCCCCCCCCHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
RQTGQDKFAGTTKCNLDHLPTKAEFNASCRLYRDGVGNYYPPPLAFERIDIPEQLAAQLH
EECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEECCCCHHHHHHHHH
NLEPREQSKQCFQYKLEVWNRAHAEMGITGTDIFYQTDKNIKLDRNYKLRPEDRYIQTEK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCCCCEECHHH
YGRREIQKRYEHQFQAGSLLPDILIKTPQNDIHFSYRFAGDAYANKRFEEFERAIKTKYG
HHHHHHHHHHHHHHHCCCCCCHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCC
SDTEIKLKSKSGIMHDSKYLESWERGSADIRFAEFAGENRAHNKQFPAATVNMGRQPDGQ
CCCEEEEECCCCCCCCHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCHHHCCCCCCCCC
GGMTRDRHVSVDYLLQNLPNSPWTQALKEGKLWDRVQVLARDGNRYMSPSRLEYSDPEHF
CCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
TQLMDQVGLPVSMGRQSHANSVKFEQFDRQAAVIVADGPNLREVPDLSPEKLQQLSQKDV
HHHHHHHCCCHHCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCE
LIADRNEKGQRTGTYTNVVEYERLMMKLPSDAAQLLAEPSDRYSRAFVRPEPALPPISDS
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHCCCCCCCCCCCCCCC
RRTYESRPRGPTVNSL
CHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3549694; 2194232; 11743193; 11743194; 8637884; 1615325