Click here to switch to the map view.

The map label for this gene is virA

Identifier: 16119781

GI number: 16119781

Start: 180831

End: 183332

Strand: Direct

Name: virA

Synonym: Atu6166

Alternate gene names: 16119781

Gene position: 180831-183332 (Clockwise)

Preceding gene: 159161997

Following gene: 41223307

Centisome position: 84.41

GC content: 52.4

Gene sequence:

>2502_bases
ATGAATGGAAGGTATTCACCGTCTCGGCAAGATTTCAAGACAGGCGCCAAGCCTTGGTCTATCCTGGCCTTGGTAGTTGC
TGCAATGATTTTTGCCTTGATGGCGATTACGTCTTGGCAGGACAATGAAACCAATCGGGCGATCCTGACCCAATTGCGAG
CTATTAACATCGACAGTGCTTCGCTGCAGCGGGATGTACTCCGCGCGGAAGCGGGTGTGGTGGCGAACTACCGGCCCATT
ATCTCCAGGTTGGGAGCTTTGCGGAAGAACCTGGAAAATTTGAAGCGACTATTTAAACAATCTCATCTTGTGATCGGCAA
TGATTTCTCTCAACTGCTCGACAAGCTAAAGGTGTCTGTGGATACGACCGACGCGGCCGTTGCAGCCTTCGGAGCGCAAA
ACGTGCTCCTGCAAGATTCGCTTGCCAGCTTCACTCGCGCGCTTAGTATTCTTCCCAAAATGTCGTCGACGGATCAGACG
GTCGAAAATTCGAACGAATTGGGCAGCCTGATGCTGCGGTTTGTGCGTCAGCCAAGCCCAGCACTCTCGTTGGAGATCAG
TCACGAACTCGACATGCTCCAAAAAGCTAGCGGTGGGGCTGAAGTTCCTATCCGTATACTTGCACGCGAGGGTCGCGTCA
TCTTGTCGATTTTGCCCCGTGTGAACGATGCCGTAAACATGATTCAGACCTCCGACACCGCTGAAATTGCCGAAAGATTG
GAGCGCAAGTGTTTGGAGGCCTATAGCTTGCAAAGCGTGAGGGAGCAGCGGGCACGGATCTTCTTGGGTTCCGTTTCGGT
GGGCCTTTGCATCTACATCATCTCACTGGTCTATAGGCTGCGTCGGAAAACGGCTTGGTTAACGCGGCGTTTGGATTACG
AAGAGGTAATCAAAGAGATTGGGGTTTGTTTCGAGGGGGGAGGGGCCACAGCGTCGTCCCTCAATTCGTCCGCGCAAGCT
GCGCTTGGAATTATTCAACGCTTCTTTAATGCGGAATCGTGTGCACTAGCATTGGTGGACCATGGTGACAGGTGGGCTGT
CGAAAGTTTCGCTGCGAAGCTGCCTGAGCCCGTCTGGGAGGACCTCGCGCTACGCGAGATGGTTTCTCTTGCCAGAGCGG
ATGAGCGTGCGTCAGTATTCCGCATCATGTCGACGCGAAAGGTCAGCTGCCTTCCTCCGGAGACTCCGGGCGTTTCTATG
CTGCTGGCACACAAATCTACGGATCAACTGATAGCGATTTGTTCCCTCGGTTACCAGGGCTATCGTCTGAAATCTTGTCC
AGGCGAAGTTCAGCTTCTTGAACTCGCCACCGCCTGCCTCTGCCACTATATCGATGTCCGGCGTAAGCAGACCGAATGCG
ATATTCTGGAGAGGCGATTAGAGCATGCGGAACGTCTTCAGGCAGTTGGTACACTTGCTGGTGGAATAGCGCATGAGTTC
AACAACATTTTGGGAGCAATCCTCGGGTACGCTGAAATGGCGCAAAACATGCTGCGTCGGTCATCTGTCACCCGAAGACA
CATTGACCAAATTATTTCGTCGGGTGACAGAGCCAGGCTCATTATCGATCAGATCTTGACTCTAAGTCGAAAACTAGAAC
GCGTGACAAAGCCGTTCAGTGTCTCCGAACTCGTAATGGAAATTGCTCCCTTATTGCGTGTTGCATTGCAGCGCAACATC
GAGCTGAAGTTCAAGTTTGACGACAAGAAGAGCGTAGTCGAAGGAAGCCCGCTAGAGGTTCAGCAGATGCTGATGAATCT
TTGCAAGAACGCTTCCCAGGCGTTTACCGCCGATGGTCAAATCGACATCATCGTTAGCCGAATTTTTGTATCTCGACAGA
AAGTACTGGCGCATGGTGTTATGCCAGCTGGCGACTATGTTCTTCTTTCTGTCAGCGACGACGGTGAAGGCATTGCCGAA
ACTGTGCTCCCCCACATTTTTGAGCCTTTCTTTACAACACGCTCTTGCAGCGGCGGCACGGGTCTAGGTCTTGCTGCCGT
GCACGGTCATGTCAGCGCGCTTGCAGGATATATTGACGTTACTTCAGCCGTAGGGCGAGGGACGCGCTTCGACATTTATC
TACCTCCTTCCTCGAAGAAGCCCGTCAGCCCGGACGCGTTTTTTGGGCCCTGTAAAACACCGCGTGGCAACGGAGAAATT
GTGGCATTGATTGAGCCAGATCCTGTCTTGCGGGAGGTGTACGAAGACAAGATCGCCGCTCTGGGCTATGAGCCGGTGGG
CTTTAAGACATGTGCAGACCTTTGCAATTGGATATCAAAAGGCAAGCAAGCCGATCTGGTTCTAGTTGACCAATCGTCTC
TTCCCGAGAATCAGAGTGCTACTGCTTTGCACGCAGCCTTCAAGACGGCGTCCATCATCATTGGAGGAAGTGATCTTAAA
ATGTCACTTTCCAGCGATGACATGACGTCCGCGCTTTTTCTGCCCAAACCTATATCCTCCAGGACGATGGCCTACGCGAT
TCGTACCAAGATCAAAGCCTAG

Upstream 100 bases:

>100_bases
GAGTCGACGTTTGTTGCTTCAAACCCATTTACAAACCCTACTGTGCGGCCTAAGGGCCAACGGGGTGGGACTGAGCGCTG
GTACGAGGACGTAAGTGCGG

Downstream 100 bases:

>100_bases
AGTTGAGGATGTTTTTCAGGAGACTCGACCAGGGTAATCAGCACGTCTGTTCGGCGCGCCTATAGCTATGGTTTCTCGCA
ATCGCTTTGGGCAGTCGGTT

Product: two-component VirA-like sensor kinase

Products: NA

Alternate protein names: WHR virA

Number of amino acids: Translated: 833; Mature: 833

Protein sequence:

>833_residues
MNGRYSPSRQDFKTGAKPWSILALVVAAMIFALMAITSWQDNETNRAILTQLRAINIDSASLQRDVLRAEAGVVANYRPI
ISRLGALRKNLENLKRLFKQSHLVIGNDFSQLLDKLKVSVDTTDAAVAAFGAQNVLLQDSLASFTRALSILPKMSSTDQT
VENSNELGSLMLRFVRQPSPALSLEISHELDMLQKASGGAEVPIRILAREGRVILSILPRVNDAVNMIQTSDTAEIAERL
ERKCLEAYSLQSVREQRARIFLGSVSVGLCIYIISLVYRLRRKTAWLTRRLDYEEVIKEIGVCFEGGGATASSLNSSAQA
ALGIIQRFFNAESCALALVDHGDRWAVESFAAKLPEPVWEDLALREMVSLARADERASVFRIMSTRKVSCLPPETPGVSM
LLAHKSTDQLIAICSLGYQGYRLKSCPGEVQLLELATACLCHYIDVRRKQTECDILERRLEHAERLQAVGTLAGGIAHEF
NNILGAILGYAEMAQNMLRRSSVTRRHIDQIISSGDRARLIIDQILTLSRKLERVTKPFSVSELVMEIAPLLRVALQRNI
ELKFKFDDKKSVVEGSPLEVQQMLMNLCKNASQAFTADGQIDIIVSRIFVSRQKVLAHGVMPAGDYVLLSVSDDGEGIAE
TVLPHIFEPFFTTRSCSGGTGLGLAAVHGHVSALAGYIDVTSAVGRGTRFDIYLPPSSKKPVSPDAFFGPCKTPRGNGEI
VALIEPDPVLREVYEDKIAALGYEPVGFKTCADLCNWISKGKQADLVLVDQSSLPENQSATALHAAFKTASIIIGGSDLK
MSLSSDDMTSALFLPKPISSRTMAYAIRTKIKA

Sequences:

>Translated_833_residues
MNGRYSPSRQDFKTGAKPWSILALVVAAMIFALMAITSWQDNETNRAILTQLRAINIDSASLQRDVLRAEAGVVANYRPI
ISRLGALRKNLENLKRLFKQSHLVIGNDFSQLLDKLKVSVDTTDAAVAAFGAQNVLLQDSLASFTRALSILPKMSSTDQT
VENSNELGSLMLRFVRQPSPALSLEISHELDMLQKASGGAEVPIRILAREGRVILSILPRVNDAVNMIQTSDTAEIAERL
ERKCLEAYSLQSVREQRARIFLGSVSVGLCIYIISLVYRLRRKTAWLTRRLDYEEVIKEIGVCFEGGGATASSLNSSAQA
ALGIIQRFFNAESCALALVDHGDRWAVESFAAKLPEPVWEDLALREMVSLARADERASVFRIMSTRKVSCLPPETPGVSM
LLAHKSTDQLIAICSLGYQGYRLKSCPGEVQLLELATACLCHYIDVRRKQTECDILERRLEHAERLQAVGTLAGGIAHEF
NNILGAILGYAEMAQNMLRRSSVTRRHIDQIISSGDRARLIIDQILTLSRKLERVTKPFSVSELVMEIAPLLRVALQRNI
ELKFKFDDKKSVVEGSPLEVQQMLMNLCKNASQAFTADGQIDIIVSRIFVSRQKVLAHGVMPAGDYVLLSVSDDGEGIAE
TVLPHIFEPFFTTRSCSGGTGLGLAAVHGHVSALAGYIDVTSAVGRGTRFDIYLPPSSKKPVSPDAFFGPCKTPRGNGEI
VALIEPDPVLREVYEDKIAALGYEPVGFKTCADLCNWISKGKQADLVLVDQSSLPENQSATALHAAFKTASIIIGGSDLK
MSLSSDDMTSALFLPKPISSRTMAYAIRTKIKA
>Mature_833_residues
MNGRYSPSRQDFKTGAKPWSILALVVAAMIFALMAITSWQDNETNRAILTQLRAINIDSASLQRDVLRAEAGVVANYRPI
ISRLGALRKNLENLKRLFKQSHLVIGNDFSQLLDKLKVSVDTTDAAVAAFGAQNVLLQDSLASFTRALSILPKMSSTDQT
VENSNELGSLMLRFVRQPSPALSLEISHELDMLQKASGGAEVPIRILAREGRVILSILPRVNDAVNMIQTSDTAEIAERL
ERKCLEAYSLQSVREQRARIFLGSVSVGLCIYIISLVYRLRRKTAWLTRRLDYEEVIKEIGVCFEGGGATASSLNSSAQA
ALGIIQRFFNAESCALALVDHGDRWAVESFAAKLPEPVWEDLALREMVSLARADERASVFRIMSTRKVSCLPPETPGVSM
LLAHKSTDQLIAICSLGYQGYRLKSCPGEVQLLELATACLCHYIDVRRKQTECDILERRLEHAERLQAVGTLAGGIAHEF
NNILGAILGYAEMAQNMLRRSSVTRRHIDQIISSGDRARLIIDQILTLSRKLERVTKPFSVSELVMEIAPLLRVALQRNI
ELKFKFDDKKSVVEGSPLEVQQMLMNLCKNASQAFTADGQIDIIVSRIFVSRQKVLAHGVMPAGDYVLLSVSDDGEGIAE
TVLPHIFEPFFTTRSCSGGTGLGLAAVHGHVSALAGYIDVTSAVGRGTRFDIYLPPSSKKPVSPDAFFGPCKTPRGNGEI
VALIEPDPVLREVYEDKIAALGYEPVGFKTCADLCNWISKGKQADLVLVDQSSLPENQSATALHAAFKTASIIIGGSDLK
MSLSSDDMTSALFLPKPISSRTMAYAIRTKIKA

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1790436, Length=275, Percent_Identity=30.5454545454545, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=31.7460317460317, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1790300, Length=242, Percent_Identity=29.7520661157025, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87081816, Length=397, Percent_Identity=27.9596977329975, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=289, Percent_Identity=25.6055363321799, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=27.7056277056277, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=271, Percent_Identity=26.1992619926199, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1790346, Length=250, Percent_Identity=24.4, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VIRA_AGRT5 (P18540)

Other databases:

- EMBL:   J03320
- EMBL:   L48210
- EMBL:   AE007871
- PIR:   AD3248
- PIR:   S06972
- RefSeq:   NP_396486.1
- ProteinModelPortal:   P18540
- STRING:   P18540
- GeneID:   1137489
- GenomeReviews:   AE007871_GR
- KEGG:   atu:Atu6166
- eggNOG:   COG0642
- HOGENOM:   HBG301729
- OMA:   RAINIDS
- ProtClustDB:   PRK13837
- BioCyc:   ATUM176299-1:ATU6166-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 91323; Mature: 91323

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x9465e8c)-; HASH(0xbe00dd8)-;

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGRYSPSRQDFKTGAKPWSILALVVAAMIFALMAITSWQDNETNRAILTQLRAINIDSA
CCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHH
SLQRDVLRAEAGVVANYRPIISRLGALRKNLENLKRLFKQSHLVIGNDFSQLLDKLKVSV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCC
DTTDAAVAAFGAQNVLLQDSLASFTRALSILPKMSSTDQTVENSNELGSLMLRFVRQPSP
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHCCCC
ALSLEISHELDMLQKASGGAEVPIRILAREGRVILSILPRVNDAVNMIQTSDTAEIAERL
CEEEEEHHHHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHH
ERKCLEAYSLQSVREQRARIFLGSVSVGLCIYIISLVYRLRRKTAWLTRRLDYEEVIKEI
HHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GVCFEGGGATASSLNSSAQAALGIIQRFFNAESCALALVDHGDRWAVESFAAKLPEPVWE
CCEECCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCHHHH
DLALREMVSLARADERASVFRIMSTRKVSCLPPETPGVSMLLAHKSTDQLIAICSLGYQG
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCC
YRLKSCPGEVQLLELATACLCHYIDVRRKQTECDILERRLEHAERLQAVGTLAGGIAHEF
CEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNILGAILGYAEMAQNMLRRSSVTRRHIDQIISSGDRARLIIDQILTLSRKLERVTKPFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VSELVMEIAPLLRVALQRNIELKFKFDDKKSVVEGSPLEVQQMLMNLCKNASQAFTADGQ
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHCCCCCCC
IDIIVSRIFVSRQKVLAHGVMPAGDYVLLSVSDDGEGIAETVLPHIFEPFFTTRSCSGGT
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC
GLGLAAVHGHVSALAGYIDVTSAVGRGTRFDIYLPPSSKKPVSPDAFFGPCKTPRGNGEI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCE
VALIEPDPVLREVYEDKIAALGYEPVGFKTCADLCNWISKGKQADLVLVDQSSLPENQSA
EEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
TALHAAFKTASIIIGGSDLKMSLSSDDMTSALFLPKPISSRTMAYAIRTKIKA
HHHHHHHHHEEEEECCCCCEEEECCCCCCCEEECCCCCCCHHHHHHHHHHCCH
>Mature Secondary Structure
MNGRYSPSRQDFKTGAKPWSILALVVAAMIFALMAITSWQDNETNRAILTQLRAINIDSA
CCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHH
SLQRDVLRAEAGVVANYRPIISRLGALRKNLENLKRLFKQSHLVIGNDFSQLLDKLKVSV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCC
DTTDAAVAAFGAQNVLLQDSLASFTRALSILPKMSSTDQTVENSNELGSLMLRFVRQPSP
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHCCCC
ALSLEISHELDMLQKASGGAEVPIRILAREGRVILSILPRVNDAVNMIQTSDTAEIAERL
CEEEEEHHHHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHH
ERKCLEAYSLQSVREQRARIFLGSVSVGLCIYIISLVYRLRRKTAWLTRRLDYEEVIKEI
HHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GVCFEGGGATASSLNSSAQAALGIIQRFFNAESCALALVDHGDRWAVESFAAKLPEPVWE
CCEECCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCHHHH
DLALREMVSLARADERASVFRIMSTRKVSCLPPETPGVSMLLAHKSTDQLIAICSLGYQG
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCC
YRLKSCPGEVQLLELATACLCHYIDVRRKQTECDILERRLEHAERLQAVGTLAGGIAHEF
CEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNILGAILGYAEMAQNMLRRSSVTRRHIDQIISSGDRARLIIDQILTLSRKLERVTKPFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VSELVMEIAPLLRVALQRNIELKFKFDDKKSVVEGSPLEVQQMLMNLCKNASQAFTADGQ
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHCCCCCCC
IDIIVSRIFVSRQKVLAHGVMPAGDYVLLSVSDDGEGIAETVLPHIFEPFFTTRSCSGGT
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC
GLGLAAVHGHVSALAGYIDVTSAVGRGTRFDIYLPPSSKKPVSPDAFFGPCKTPRGNGEI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCE
VALIEPDPVLREVYEDKIAALGYEPVGFKTCADLCNWISKGKQADLVLVDQSSLPENQSA
EEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
TALHAAFKTASIIIGGSDLKMSLSSDDMTSALFLPKPISSRTMAYAIRTKIKA
HHHHHHHHHEEEEECCCCCEEEECCCCCCCEEECCCCCCCHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194