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The map label for this gene is tktB [C]

Identifier: 160903375

GI number: 160903375

Start: 2155650

End: 2157545

Strand: Direct

Name: tktB [C]

Synonym: Pmob_1946

Alternate gene names: 160903375

Gene position: 2155650-2157545 (Clockwise)

Preceding gene: 160903374

Following gene: 160903376

Centisome position: 99.36

GC content: 36.87

Gene sequence:

>1896_bases
TTGAAAAAAAGTTTAAAAGAACTAAAAAACTTGTCGGTTATCGCCAGAGGAGATATATTGAAGATGACCACTGTGGCTAA
TTCTGGTCACCCCGCAGGGTCTATGTCTTCTATTGATATGTTTTTATCGGTTTTAAATAGGGCAAATATATTCCCAGATG
ATCCGTTTAATCCAGATAGAGACAGGATCGTGGTTAGTCATGGTCACACTTCACCAGGATTCTATGTGGCTTTAGCAAGG
ATGGGCTTTGTAGACATAGAAGAAGTTATTTCAGGATTCAGATATGCTGGGAGCATATTTGAAGGGCATGTTACCCGTGG
AATACCTGGTGTTGAGTGGTCAACAGGCAATTTAGGTCAAGGTTTATCAGCTGGGATTGGAATGGCTTTGGCAGCAAAAA
AGAGGGGAAAAGACTATAGAGTTTACGTATTTAGTAGTGATGGAGAAAGCTCAAAAGGGCAAATTGCAGAAGCTCGAAGA
ACTGCCATAAAAGAAGGCTTAAATAACCTAATAGTATTACTTGATTACAACGATATTCAAATATCTGGAAGAGCCAGAGA
TATCTTATCAGTAAATATAGTTGGAGAATATGAAGCGGCTGGCTGGAACGTTATAGAAATCGATGGACACAATTTTGATC
AAATCAATAAGGCTTTAGAAGTAGCTGAAAATGAACCATTAAGGCCAACTGTGATTGTAGCTAAGACGATTATAGGGAAA
GGAGTTTCTTTTATGGAAAACACCCCAACCTATCACGGTAAAGCACTCACTAAAGAACAGCTAAGTAAAGCTTTAGAAGA
ATTAGGTTTAGAAAACGATGTGGAAAAGTACATTGAAAAAAGAAAAAATATGGCTTTAACTAGGGATAAACTAAGTTATC
CAAATATTGAATTAAATGTTGAGACAGGACAACCTATAGTATATGGCAAGGGAGAAAAGGTTGCCAATCGTAATGCTTTT
GGTAACGCTATTGCTGATCTTGCGAAACTGAACATGGAGAATTTTCCAGTAGTTGCGATCGATTGTGATCTGAAACCATC
CGTTAATTTGGAAAAATTTGAAAAAGTCAATCCCGAAGGTTATATTCAAATTGGTATTGAGGAGCATAACGCAGCCACCA
TTGGAGGAGCATTGTCCGTTAGTGGAGCATTAACTTTTTTCGCTGATTTTGGGGTATTTGGCTTGGATGAGGCATTTAAT
CAGCAAAGATTAAACGATATTAATCACACTAATTTAAAGACTGTTGTCACCCACTGTGGTATCGATGTTGGAGAAGATGG
TAAGACTCATCATGAAGTTAATTATATTGGGATAGTCAGAAGTTTATACCATACTAAATTGATCGTACCTTGTGATGCCA
ATCAAACTGATAAAGCGATTAGGTATGCTGCCAAAGTTCCTGGCAACTTTGTAATCGCTATGGGAAGATCTAACTTGCCA
ATCTTGTTAGATGAAGAGGGTAACGTTTATTACAATAACGATTATAACTTCGAGTATGGGAAGTTGGATGTTTTTAGAAA
AGGTAGAGACCTAACAGTATTCACATATGGAAGCTTCGCTCATTTAGCGGTGGAAGCTGCTGATAAGTTGAAAGAAGAAG
ATATACATATTACAGTCATTGGTGTACCGACTCCTTTAGATTTTGACCTTACTCAAGTGAAAGAATACGTTGACAATACT
ATAGTATTAACCTTAGAAGATCACAACGTAGAAAATGGTTTGTCAAATGAACTGTCAAAAGCTATGATCAAAAATTCTAT
GAAACCTTCTTATTTTGAACCTATGGGATTAAAAGAATATGCACCGTCTGGAACAATCAAAGATTTGCTAAGGGTTCATG
GATTTGATGTAGAATCGCTAGTAAAAAAGATGAAAGGATTAATTGAGAGCAAATGA

Upstream 100 bases:

>100_bases
TTACAACGATGCTTATTGTTAGTGGATTAGGCACATTACTATCAATTATCATTCGAAGATTTTTCTAATAATGAATGTAA
ATTCCTTGGAGGTGTATTCG

Downstream 100 bases:

>100_bases
AGCATGAGGATGATTTAAAATTAACCTTGCAAGAGGAACAAAATGTAAAAAAAGCAAAAAAGGAGCTCCTATTGCCACCA
TGCGTGAAAGAGAGCGTGTT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MKKSLKELKNLSVIARGDILKMTTVANSGHPAGSMSSIDMFLSVLNRANIFPDDPFNPDRDRIVVSHGHTSPGFYVALAR
MGFVDIEEVISGFRYAGSIFEGHVTRGIPGVEWSTGNLGQGLSAGIGMALAAKKRGKDYRVYVFSSDGESSKGQIAEARR
TAIKEGLNNLIVLLDYNDIQISGRARDILSVNIVGEYEAAGWNVIEIDGHNFDQINKALEVAENEPLRPTVIVAKTIIGK
GVSFMENTPTYHGKALTKEQLSKALEELGLENDVEKYIEKRKNMALTRDKLSYPNIELNVETGQPIVYGKGEKVANRNAF
GNAIADLAKLNMENFPVVAIDCDLKPSVNLEKFEKVNPEGYIQIGIEEHNAATIGGALSVSGALTFFADFGVFGLDEAFN
QQRLNDINHTNLKTVVTHCGIDVGEDGKTHHEVNYIGIVRSLYHTKLIVPCDANQTDKAIRYAAKVPGNFVIAMGRSNLP
ILLDEEGNVYYNNDYNFEYGKLDVFRKGRDLTVFTYGSFAHLAVEAADKLKEEDIHITVIGVPTPLDFDLTQVKEYVDNT
IVLTLEDHNVENGLSNELSKAMIKNSMKPSYFEPMGLKEYAPSGTIKDLLRVHGFDVESLVKKMKGLIESK

Sequences:

>Translated_631_residues
MKKSLKELKNLSVIARGDILKMTTVANSGHPAGSMSSIDMFLSVLNRANIFPDDPFNPDRDRIVVSHGHTSPGFYVALAR
MGFVDIEEVISGFRYAGSIFEGHVTRGIPGVEWSTGNLGQGLSAGIGMALAAKKRGKDYRVYVFSSDGESSKGQIAEARR
TAIKEGLNNLIVLLDYNDIQISGRARDILSVNIVGEYEAAGWNVIEIDGHNFDQINKALEVAENEPLRPTVIVAKTIIGK
GVSFMENTPTYHGKALTKEQLSKALEELGLENDVEKYIEKRKNMALTRDKLSYPNIELNVETGQPIVYGKGEKVANRNAF
GNAIADLAKLNMENFPVVAIDCDLKPSVNLEKFEKVNPEGYIQIGIEEHNAATIGGALSVSGALTFFADFGVFGLDEAFN
QQRLNDINHTNLKTVVTHCGIDVGEDGKTHHEVNYIGIVRSLYHTKLIVPCDANQTDKAIRYAAKVPGNFVIAMGRSNLP
ILLDEEGNVYYNNDYNFEYGKLDVFRKGRDLTVFTYGSFAHLAVEAADKLKEEDIHITVIGVPTPLDFDLTQVKEYVDNT
IVLTLEDHNVENGLSNELSKAMIKNSMKPSYFEPMGLKEYAPSGTIKDLLRVHGFDVESLVKKMKGLIESK
>Mature_631_residues
MKKSLKELKNLSVIARGDILKMTTVANSGHPAGSMSSIDMFLSVLNRANIFPDDPFNPDRDRIVVSHGHTSPGFYVALAR
MGFVDIEEVISGFRYAGSIFEGHVTRGIPGVEWSTGNLGQGLSAGIGMALAAKKRGKDYRVYVFSSDGESSKGQIAEARR
TAIKEGLNNLIVLLDYNDIQISGRARDILSVNIVGEYEAAGWNVIEIDGHNFDQINKALEVAENEPLRPTVIVAKTIIGK
GVSFMENTPTYHGKALTKEQLSKALEELGLENDVEKYIEKRKNMALTRDKLSYPNIELNVETGQPIVYGKGEKVANRNAF
GNAIADLAKLNMENFPVVAIDCDLKPSVNLEKFEKVNPEGYIQIGIEEHNAATIGGALSVSGALTFFADFGVFGLDEAFN
QQRLNDINHTNLKTVVTHCGIDVGEDGKTHHEVNYIGIVRSLYHTKLIVPCDANQTDKAIRYAAKVPGNFVIAMGRSNLP
ILLDEEGNVYYNNDYNFEYGKLDVFRKGRDLTVFTYGSFAHLAVEAADKLKEEDIHITVIGVPTPLDFDLTQVKEYVDNT
IVLTLEDHNVENGLSNELSKAMIKNSMKPSYFEPMGLKEYAPSGTIKDLLRVHGFDVESLVKKMKGLIESK

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=642, Percent_Identity=31.3084112149533, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI4507521, Length=642, Percent_Identity=31.3084112149533, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI133778974, Length=591, Percent_Identity=31.1336717428088, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI225637459, Length=640, Percent_Identity=28.125, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI225637461, Length=584, Percent_Identity=28.9383561643836, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI225637463, Length=584, Percent_Identity=28.9383561643836, Blast_Score=212, Evalue=9e-55,
Organism=Escherichia coli, GI1788808, Length=678, Percent_Identity=26.6961651917404, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI48994911, Length=686, Percent_Identity=27.6967930029155, Blast_Score=158, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17539652, Length=622, Percent_Identity=30.5466237942122, Blast_Score=241, Evalue=9e-64,
Organism=Saccharomyces cerevisiae, GI6325331, Length=681, Percent_Identity=26.431718061674, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6319593, Length=673, Percent_Identity=24.962852897474, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI45551847, Length=597, Percent_Identity=31.4907872696817, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI45550715, Length=597, Percent_Identity=31.4907872696817, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24645119, Length=542, Percent_Identity=31.3653136531365, Blast_Score=230, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24666278, Length=595, Percent_Identity=30.5882352941176, Blast_Score=223, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 69545; Mature: 69545

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSLKELKNLSVIARGDILKMTTVANSGHPAGSMSSIDMFLSVLNRANIFPDDPFNPDR
CCCHHHHHHCCEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DRIVVSHGHTSPGFYVALARMGFVDIEEVISGFRYAGSIFEGHVTRGIPGVEWSTGNLGQ
CEEEEECCCCCCCCEEHHHHCCCCCHHHHHHHHHHHCHHHCCHHHCCCCCCCCCCCCCCC
GLSAGIGMALAAKKRGKDYRVYVFSSDGESSKGQIAEARRTAIKEGLNNLIVLLDYNDIQ
CCHHCCCHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEE
ISGRARDILSVNIVGEYEAAGWNVIEIDGHNFDQINKALEVAENEPLRPTVIVAKTIIGK
ECCCCCEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHC
GVSFMENTPTYHGKALTKEQLSKALEELGLENDVEKYIEKRKNMALTRDKLSYPNIELNV
CCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEHHCCCCCCEEEEE
ETGQPIVYGKGEKVANRNAFGNAIADLAKLNMENFPVVAIDCDLKPSVNLEKFEKVNPEG
ECCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHCCCCCC
YIQIGIEEHNAATIGGALSVSGALTFFADFGVFGLDEAFNQQRLNDINHTNLKTVVTHCG
EEEEEEECCCCEEECCEEEHHHHHEEHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCC
IDVGEDGKTHHEVNYIGIVRSLYHTKLIVPCDANQTDKAIRYAAKVPGNFVIAMGRSNLP
CCCCCCCCCCCEEHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCC
ILLDEEGNVYYNNDYNFEYGKLDVFRKGRDLTVFTYGSFAHLAVEAADKLKEEDIHITVI
EEEECCCCEEECCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEE
GVPTPLDFDLTQVKEYVDNTIVLTLEDHNVENGLSNELSKAMIKNSMKPSYFEPMGLKEY
ECCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHC
APSGTIKDLLRVHGFDVESLVKKMKGLIESK
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKSLKELKNLSVIARGDILKMTTVANSGHPAGSMSSIDMFLSVLNRANIFPDDPFNPDR
CCCHHHHHHCCEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DRIVVSHGHTSPGFYVALARMGFVDIEEVISGFRYAGSIFEGHVTRGIPGVEWSTGNLGQ
CEEEEECCCCCCCCEEHHHHCCCCCHHHHHHHHHHHCHHHCCHHHCCCCCCCCCCCCCCC
GLSAGIGMALAAKKRGKDYRVYVFSSDGESSKGQIAEARRTAIKEGLNNLIVLLDYNDIQ
CCHHCCCHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEE
ISGRARDILSVNIVGEYEAAGWNVIEIDGHNFDQINKALEVAENEPLRPTVIVAKTIIGK
ECCCCCEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHC
GVSFMENTPTYHGKALTKEQLSKALEELGLENDVEKYIEKRKNMALTRDKLSYPNIELNV
CCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEHHCCCCCCEEEEE
ETGQPIVYGKGEKVANRNAFGNAIADLAKLNMENFPVVAIDCDLKPSVNLEKFEKVNPEG
ECCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHCCCCCC
YIQIGIEEHNAATIGGALSVSGALTFFADFGVFGLDEAFNQQRLNDINHTNLKTVVTHCG
EEEEEEECCCCEEECCEEEHHHHHEEHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCC
IDVGEDGKTHHEVNYIGIVRSLYHTKLIVPCDANQTDKAIRYAAKVPGNFVIAMGRSNLP
CCCCCCCCCCCEEHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCC
ILLDEEGNVYYNNDYNFEYGKLDVFRKGRDLTVFTYGSFAHLAVEAADKLKEEDIHITVI
EEEECCCCEEECCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEE
GVPTPLDFDLTQVKEYVDNTIVLTLEDHNVENGLSNELSKAMIKNSMKPSYFEPMGLKEY
ECCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHC
APSGTIKDLLRVHGFDVESLVKKMKGLIESK
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]