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The map label for this gene is hsdM [C]

Identifier: 160903325

GI number: 160903325

Start: 2097082

End: 2098617

Strand: Direct

Name: hsdM [C]

Synonym: Pmob_1896

Alternate gene names: 160903325

Gene position: 2097082-2098617 (Clockwise)

Preceding gene: 160903324

Following gene: 160903326

Centisome position: 96.66

GC content: 37.11

Gene sequence:

>1536_bases
ATGGCTCAAAATAATCTTGATACCAAAACTTTAGAAAACTGGCTTTGGGAAGCTGCTTGTAAAATAAGAGGACCTATAGA
TGCCCCCAAATACAAGGATTATATCTTACCTTTGATATTTTTAAAAAGACTCTCTGACGTATTCGAAGACGAATTGAACG
AGTTATCAGAAAAGTTTGGTTCACTTGAGACAGCAGAAGAATTTAGCAGGATTGATCCAGGGTTAGTTCGTTTTTATTTG
CCACCAGAAGCGAGATGGTCTGAAGTTGCTAAAAAAACTACAAATGTCGGAGAATATTTAACCGACGCCGTAAGAACAAT
TGCAAGATACAATCCCAAACTTCAAGGTGTAATAGATATTGTAGATTTCAACGCAACTGCAGGTGGTCAAAGAATTATAA
GTGACGATGTGTTGGTAGCATTAATTGATGTTTTAGGAAGACATCGTCTTGGCTTGAAAGATGTTGATCCGGATATTTTA
GGTCGTGCATACGAATATTTGTTGAGAAAATTTGCCGAAGGTTCTGGGCAAAGTGCTGGTGAGTTTTACACTCCTGGTGA
GGTAGCGATTTTGATGTCAAAAATCTTAGACCCAAAACCAGGTAATGAAGTCTATGATCCTTGTTGTGGATCTGGGGGCT
TGCTGATTAAAGCTCATCTGAGATTTAAAGAAAAATACTCAGAAGACAGAACTAAAGAACCTCTTAAATTCTATGGGCAA
GAAATCTTGCATTCAACGTATGCAATGGCAAAAATGAATATCTTTATACACGACATGGAAGCACAAATTGCCCTTGGAGA
TACGATGAATAGACCTGCGTTTACAACTTCTGAAGGACCGCTCAAGAAATTCGATTTAGTAACTGCAAATCCAATGTGGA
ATCAAACATTCTCACAATCTGTTTATGAAAACGATCCTTACAATAGATTCGTTTTTGGATACCCTCCATCAAACAGCGCA
GACTGGGGATGGATCCAGCATATGTTTGCTTCATTGAAAAATGATGGTAAGATGGCTTTAGTAATTGATACAGGTGCTGT
ATCAAGGGGTAGTGGAAATGTTGGAAAAAATAGAGAAAGAGATATAAGAAAAGAATTTGTTGAAAAAGATCTTGTAGAAT
CGGTTTTATTACTTCCTGAAAATTTATTCTACAATACTTCAGCACCAGGGGTTATCATAGTGATTAATAAGTTAAAACCA
GCACAAAGGCAAGACCAGATACTTCTCATAAACGCATCAAAGCTCTATGAAAAAGGAAGACCTAAGAACTTCTTGCCTGA
TGAGAGTGTTGAAAGGATAGCAGAGATCTATCTCAACTGGAAAGAAGAAGAGGGAATAAGTAAAATTATTTCTAAAGAAG
AAGCCGCGAAAAATGATTATAACTTAAGCCCCTCCCGTTATGTTGCTCAAAATGGTGAAGACGAAACACTGCCTTTGGAG
GATGCTGTTGTGCAGTTAAAAGAGGCAGAAGAAGAAAGAAAAGAAGCCGATGAAAAATTAGAGATTATTTTAAAAGAGAT
GGGATTATGGAATTAG

Upstream 100 bases:

>100_bases
AACGGCAATTTCCACGTTCCAAAAAGGCCTCTTGAAAAGGTTATTCATTTTGATAAATTTTGATTATAATTATTGATTTG
GAACACAGGGAGGACGACAA

Downstream 100 bases:

>100_bases
ATCTTTACCAGAAAGAAGAATACAAAGAGACAGAACTCGGCTTGCTACCGAAAGATTGGGAAGTTGTGAGGTTGGGGGAG
GTTTCTGAACTTCAACAAGG

Product: N-6 DNA methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MAQNNLDTKTLENWLWEAACKIRGPIDAPKYKDYILPLIFLKRLSDVFEDELNELSEKFGSLETAEEFSRIDPGLVRFYL
PPEARWSEVAKKTTNVGEYLTDAVRTIARYNPKLQGVIDIVDFNATAGGQRIISDDVLVALIDVLGRHRLGLKDVDPDIL
GRAYEYLLRKFAEGSGQSAGEFYTPGEVAILMSKILDPKPGNEVYDPCCGSGGLLIKAHLRFKEKYSEDRTKEPLKFYGQ
EILHSTYAMAKMNIFIHDMEAQIALGDTMNRPAFTTSEGPLKKFDLVTANPMWNQTFSQSVYENDPYNRFVFGYPPSNSA
DWGWIQHMFASLKNDGKMALVIDTGAVSRGSGNVGKNRERDIRKEFVEKDLVESVLLLPENLFYNTSAPGVIIVINKLKP
AQRQDQILLINASKLYEKGRPKNFLPDESVERIAEIYLNWKEEEGISKIISKEEAAKNDYNLSPSRYVAQNGEDETLPLE
DAVVQLKEAEEERKEADEKLEIILKEMGLWN

Sequences:

>Translated_511_residues
MAQNNLDTKTLENWLWEAACKIRGPIDAPKYKDYILPLIFLKRLSDVFEDELNELSEKFGSLETAEEFSRIDPGLVRFYL
PPEARWSEVAKKTTNVGEYLTDAVRTIARYNPKLQGVIDIVDFNATAGGQRIISDDVLVALIDVLGRHRLGLKDVDPDIL
GRAYEYLLRKFAEGSGQSAGEFYTPGEVAILMSKILDPKPGNEVYDPCCGSGGLLIKAHLRFKEKYSEDRTKEPLKFYGQ
EILHSTYAMAKMNIFIHDMEAQIALGDTMNRPAFTTSEGPLKKFDLVTANPMWNQTFSQSVYENDPYNRFVFGYPPSNSA
DWGWIQHMFASLKNDGKMALVIDTGAVSRGSGNVGKNRERDIRKEFVEKDLVESVLLLPENLFYNTSAPGVIIVINKLKP
AQRQDQILLINASKLYEKGRPKNFLPDESVERIAEIYLNWKEEEGISKIISKEEAAKNDYNLSPSRYVAQNGEDETLPLE
DAVVQLKEAEEERKEADEKLEIILKEMGLWN
>Mature_510_residues
AQNNLDTKTLENWLWEAACKIRGPIDAPKYKDYILPLIFLKRLSDVFEDELNELSEKFGSLETAEEFSRIDPGLVRFYLP
PEARWSEVAKKTTNVGEYLTDAVRTIARYNPKLQGVIDIVDFNATAGGQRIISDDVLVALIDVLGRHRLGLKDVDPDILG
RAYEYLLRKFAEGSGQSAGEFYTPGEVAILMSKILDPKPGNEVYDPCCGSGGLLIKAHLRFKEKYSEDRTKEPLKFYGQE
ILHSTYAMAKMNIFIHDMEAQIALGDTMNRPAFTTSEGPLKKFDLVTANPMWNQTFSQSVYENDPYNRFVFGYPPSNSAD
WGWIQHMFASLKNDGKMALVIDTGAVSRGSGNVGKNRERDIRKEFVEKDLVESVLLLPENLFYNTSAPGVIIVINKLKPA
QRQDQILLINASKLYEKGRPKNFLPDESVERIAEIYLNWKEEEGISKIISKEEAAKNDYNLSPSRYVAQNGEDETLPLED
AVVQLKEAEEERKEADEKLEIILKEMGLWN

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=328, Percent_Identity=23.780487804878, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR011991 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57943; Mature: 57812

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNNLDTKTLENWLWEAACKIRGPIDAPKYKDYILPLIFLKRLSDVFEDELNELSEKFG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLETAEEFSRIDPGLVRFYLPPEARWSEVAKKTTNVGEYLTDAVRTIARYNPKLQGVIDI
CCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VDFNATAGGQRIISDDVLVALIDVLGRHRLGLKDVDPDILGRAYEYLLRKFAEGSGQSAG
EECCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
EFYTPGEVAILMSKILDPKPGNEVYDPCCGSGGLLIKAHLRFKEKYSEDRTKEPLKFYGQ
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHH
EILHSTYAMAKMNIFIHDMEAQIALGDTMNRPAFTTSEGPLKKFDLVTANPMWNQTFSQS
HHHHHHHHHHHEEEEEEECCCEEEECCCCCCCCEECCCCCCCCEEEEECCCCCCHHHHHH
VYENDPYNRFVFGYPPSNSADWGWIQHMFASLKNDGKMALVIDTGAVSRGSGNVGKNRER
HHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHH
DIRKEFVEKDLVESVLLLPENLFYNTSAPGVIIVINKLKPAQRQDQILLINASKLYEKGR
HHHHHHHHHHHHHHHHHCCCHHEECCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHCCC
PKNFLPDESVERIAEIYLNWKEEEGISKIISKEEAAKNDYNLSPSRYVAQNGEDETLPLE
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHH
DAVVQLKEAEEERKEADEKLEIILKEMGLWN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AQNNLDTKTLENWLWEAACKIRGPIDAPKYKDYILPLIFLKRLSDVFEDELNELSEKFG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLETAEEFSRIDPGLVRFYLPPEARWSEVAKKTTNVGEYLTDAVRTIARYNPKLQGVIDI
CCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VDFNATAGGQRIISDDVLVALIDVLGRHRLGLKDVDPDILGRAYEYLLRKFAEGSGQSAG
EECCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
EFYTPGEVAILMSKILDPKPGNEVYDPCCGSGGLLIKAHLRFKEKYSEDRTKEPLKFYGQ
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHH
EILHSTYAMAKMNIFIHDMEAQIALGDTMNRPAFTTSEGPLKKFDLVTANPMWNQTFSQS
HHHHHHHHHHHEEEEEEECCCEEEECCCCCCCCEECCCCCCCCEEEEECCCCCCHHHHHH
VYENDPYNRFVFGYPPSNSADWGWIQHMFASLKNDGKMALVIDTGAVSRGSGNVGKNRER
HHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHH
DIRKEFVEKDLVESVLLLPENLFYNTSAPGVIIVINKLKPAQRQDQILLINASKLYEKGR
HHHHHHHHHHHHHHHHHCCCHHEECCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHCCC
PKNFLPDESVERIAEIYLNWKEEEGISKIISKEEAAKNDYNLSPSRYVAQNGEDETLPLE
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHH
DAVVQLKEAEEERKEADEKLEIILKEMGLWN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]