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The map label for this gene is glnA [H]

Identifier: 160903224

GI number: 160903224

Start: 1964878

End: 1966203

Strand: Direct

Name: glnA [H]

Synonym: Pmob_1793

Alternate gene names: 160903224

Gene position: 1964878-1966203 (Clockwise)

Preceding gene: 160903223

Following gene: 160903225

Centisome position: 90.57

GC content: 37.71

Gene sequence:

>1326_bases
ATGACAAAAGAGGAACTATTGGAACAGATAGAAAGTCAAGGTATAAAGTATATTAGACTGCAAATTACTGATATCAACGG
AGCCTTGAAAAACGTAGAAATACCATCTACAGAGTTAGAATCTTCTTTGACTAACGGGACTATGTTTGATGGTTCATCGA
TTGAAGGGCTAGTGAGAATCAACGAATCCGATATGTTGCTTAAACCTGATATAGACACCTTTGCAGTTTTGCCGTGGACC
GTTGAAAGAGAAAAAGTTGGTAGATTCATTTGTGACATTTATACTTCTGATGGGAAGCATTTCCAAGGTGACCCCAGATA
TGTGTTGAAGAAAGTCATGAATGATATGAAAGAGTATGGCTATACCCCATATGCCGGTCCAGAACCAGAATTTTTTATCC
TTCCAAGGGATGAGGAAACAAGACAACCGGTATTATCTCCTCTTGATAGGGGAGGCTATTTCGATTTGCTCCCAATAGAT
TTAGGGGAAAGGGTTAGAAAAAACATGGTAGAAACTCTACAAAGTATGGGTATTAGAGTGGAGGCTGCTCACCATGAAGT
AGCAAATTCTCAACATGAAATTGATTTCAGGTACGACAACGCTCTTAGAACCGCCGACAATATTCAAACTTTTAAATTGG
TTGTAAGGACGATAGCTCTATTGAACGGGCTGTGGGCAACGTTTATGCCTAAGCCATTTTTTGGTATGAACGGCTCAGGG
ATGCACACCCATTTGAGTATCTTTAAAGACGGAAAGAATATCTTTTACGATCCAAACGGTACTTATCAATTAAGCAGTGA
GCTTAGATGGTTTATTGGAGGTGTTTTTAAGCATATAGATGCGATAACCGTTTTGGCAAATCCTACGATAAACTCATATA
AAAGGTTAGTTCCCGGATACGAAGCCCCTGTTAACATCGCATGGTCCGTATTGAATAGAAGTGCTTTAGTGAGGATACCG
ATGTCGAGAGGAGACGGAACTAGGTTGGAATTAAGATCTCCAGATCCAACAGCAAATCCTTATTTACTTTTAGCTAGTGT
ATTTTCATCAGGTTTAGAAGGTATAAAAAACAAGATAGAGCCACCTCAACCCGTTGATGGAAATATTTACGAAATGGACC
ACAAAGAAAAGAGTGAAAAAAATATTAGATATTTACCTGGTTCACTCAATGAATCCTTGGAAGCTCTGAAAAAAGACGAA
TTTATAGCCGAAATCTTGGGAGAACACATATTTAAAAAATTTATAGAATTAAAAGAAAAAGAGATTGAAGAGTTTAAGAT
AGCGGTAACTGATTGGGAGATTAATAAGTACATAAACCAATTTTGA

Upstream 100 bases:

>100_bases
ATATTTACCGATAATTAGAAATAATGAAACAATTTTCAATTTAAACTAACTTTTGAAAATAATATCTTAGCGATTTTACT
TTATTGGGAGGGAAAAATTT

Downstream 100 bases:

>100_bases
TAAACCTTTAATATCTATTATTATTTTCTTTTTTAAAAATAAAACCGGGGTTTCAAAAAGTATTATACAGAAACACACTG
TATTGGGACAGTCTCCAATA

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTKEELLEQIESQGIKYIRLQITDINGALKNVEIPSTELESSLTNGTMFDGSSIEGLVRINESDMLLKPDIDTFAVLPWT
VEREKVGRFICDIYTSDGKHFQGDPRYVLKKVMNDMKEYGYTPYAGPEPEFFILPRDEETRQPVLSPLDRGGYFDLLPID
LGERVRKNMVETLQSMGIRVEAAHHEVANSQHEIDFRYDNALRTADNIQTFKLVVRTIALLNGLWATFMPKPFFGMNGSG
MHTHLSIFKDGKNIFYDPNGTYQLSSELRWFIGGVFKHIDAITVLANPTINSYKRLVPGYEAPVNIAWSVLNRSALVRIP
MSRGDGTRLELRSPDPTANPYLLLASVFSSGLEGIKNKIEPPQPVDGNIYEMDHKEKSEKNIRYLPGSLNESLEALKKDE
FIAEILGEHIFKKFIELKEKEIEEFKIAVTDWEINKYINQF

Sequences:

>Translated_441_residues
MTKEELLEQIESQGIKYIRLQITDINGALKNVEIPSTELESSLTNGTMFDGSSIEGLVRINESDMLLKPDIDTFAVLPWT
VEREKVGRFICDIYTSDGKHFQGDPRYVLKKVMNDMKEYGYTPYAGPEPEFFILPRDEETRQPVLSPLDRGGYFDLLPID
LGERVRKNMVETLQSMGIRVEAAHHEVANSQHEIDFRYDNALRTADNIQTFKLVVRTIALLNGLWATFMPKPFFGMNGSG
MHTHLSIFKDGKNIFYDPNGTYQLSSELRWFIGGVFKHIDAITVLANPTINSYKRLVPGYEAPVNIAWSVLNRSALVRIP
MSRGDGTRLELRSPDPTANPYLLLASVFSSGLEGIKNKIEPPQPVDGNIYEMDHKEKSEKNIRYLPGSLNESLEALKKDE
FIAEILGEHIFKKFIELKEKEIEEFKIAVTDWEINKYINQF
>Mature_440_residues
TKEELLEQIESQGIKYIRLQITDINGALKNVEIPSTELESSLTNGTMFDGSSIEGLVRINESDMLLKPDIDTFAVLPWTV
EREKVGRFICDIYTSDGKHFQGDPRYVLKKVMNDMKEYGYTPYAGPEPEFFILPRDEETRQPVLSPLDRGGYFDLLPIDL
GERVRKNMVETLQSMGIRVEAAHHEVANSQHEIDFRYDNALRTADNIQTFKLVVRTIALLNGLWATFMPKPFFGMNGSGM
HTHLSIFKDGKNIFYDPNGTYQLSSELRWFIGGVFKHIDAITVLANPTINSYKRLVPGYEAPVNIAWSVLNRSALVRIPM
SRGDGTRLELRSPDPTANPYLLLASVFSSGLEGIKNKIEPPQPVDGNIYEMDHKEKSEKNIRYLPGSLNESLEALKKDEF
IAEILGEHIFKKFIELKEKEIEEFKIAVTDWEINKYINQF

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=448, Percent_Identity=25.4464285714286, Blast_Score=148, Evalue=1e-35,
Organism=Escherichia coli, GI1790301, Length=471, Percent_Identity=38.4288747346072, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI87081870, Length=440, Percent_Identity=27.9545454545455, Blast_Score=159, Evalue=5e-40,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50322; Mature: 50191

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEELLEQIESQGIKYIRLQITDINGALKNVEIPSTELESSLTNGTMFDGSSIEGLVRI
CCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCEECCCCCCEEEEE
NESDMLLKPDIDTFAVLPWTVEREKVGRFICDIYTSDGKHFQGDPRYVLKKVMNDMKEYG
CCCCEEECCCCCCEEEECEEECHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCC
YTPYAGPEPEFFILPRDEETRQPVLSPLDRGGYFDLLPIDLGERVRKNMVETLQSMGIRV
CCCCCCCCCCEEEECCCCHHCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEE
EAAHHEVANSQHEIDFRYDNALRTADNIQTFKLVVRTIALLNGLWATFMPKPFFGMNGSG
EEHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MHTHLSIFKDGKNIFYDPNGTYQLSSELRWFIGGVFKHIDAITVLANPTINSYKRLVPGY
CEEEEEEEECCCEEEECCCCCEEEHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCCC
EAPVNIAWSVLNRSALVRIPMSRGDGTRLELRSPDPTANPYLLLASVFSSGLEGIKNKIE
CCCHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
PPQPVDGNIYEMDHKEKSEKNIRYLPGSLNESLEALKKDEFIAEILGEHIFKKFIELKEK
CCCCCCCCEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIEEFKIAVTDWEINKYINQF
HHHHEEEEEECHHHHHHHHCC
>Mature Secondary Structure 
TKEELLEQIESQGIKYIRLQITDINGALKNVEIPSTELESSLTNGTMFDGSSIEGLVRI
CHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCEECCCCCCEEEEE
NESDMLLKPDIDTFAVLPWTVEREKVGRFICDIYTSDGKHFQGDPRYVLKKVMNDMKEYG
CCCCEEECCCCCCEEEECEEECHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCC
YTPYAGPEPEFFILPRDEETRQPVLSPLDRGGYFDLLPIDLGERVRKNMVETLQSMGIRV
CCCCCCCCCCEEEECCCCHHCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEE
EAAHHEVANSQHEIDFRYDNALRTADNIQTFKLVVRTIALLNGLWATFMPKPFFGMNGSG
EEHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MHTHLSIFKDGKNIFYDPNGTYQLSSELRWFIGGVFKHIDAITVLANPTINSYKRLVPGY
CEEEEEEEECCCEEEECCCCCEEEHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCCC
EAPVNIAWSVLNRSALVRIPMSRGDGTRLELRSPDPTANPYLLLASVFSSGLEGIKNKIE
CCCHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
PPQPVDGNIYEMDHKEKSEKNIRYLPGSLNESLEALKKDEFIAEILGEHIFKKFIELKEK
CCCCCCCCEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIEEFKIAVTDWEINKYINQF
HHHHEEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1348781; 10360571 [H]