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The map label for this gene is ndhF [H]

Identifier: 160903168

GI number: 160903168

Start: 1899259

End: 1900137

Strand: Direct

Name: ndhF [H]

Synonym: Pmob_1733

Alternate gene names: 160903168

Gene position: 1899259-1900137 (Clockwise)

Preceding gene: 160903167

Following gene: 160903169

Centisome position: 87.54

GC content: 32.08

Gene sequence:

>879_bases
ATGATTGAATATGATTTTTTAATTGCTAAAGATGTTGATTCTGCTTTAGAATATTTGCATAAATATGAAAATATAAAGGT
ATTAGCTGGTGGAACTGATATACTGGTAGATATACATAAAGAAAGTCCAAGATTAGAAAAATTTGATTATATATTGGATA
TTTCTAATATCAAAGGTCTTCAATATATAGATGAAATGGAAGATAACGTCGAGTTGGGAGCTTTGTGTACACATACAATG
TTAATCCAATCAAACGTTATCAACAAATATTTCCCATTTCTCGTAACTGCAGCAAAAAGTATAGGCTCCGTACAGATAAG
AAACAGAGGTACCGTTGGAGGAAATATATCTAATGCGTCTCCAGCAGCTGATTTAATTCCTCCTTTGATGGCGTTAGACT
CTAAGATAGAGCTAAGTTCTATAAATGGGAAAAGGCATGTGCCCTTAGATCAGTATATTGTAGGACCTTACAAGACCAGT
AAAAATCAAGATGAACTTGTAACTAAAATAATAATTCCAAAACTAGATGAAAATTATCGTTTTAGTTTTCAAAAAATTGG
AAGAAGAAGAGCTTTGAATATAGCAAGACTAAACTTAGCTGTCGTTGCAAAAATAAATGAACAAGACTCAAAAATTGAAG
ATATAAGAATAGTGCCAGGTTCTGCAACACCTTTTCCGATAAGATTTAAGAATATAGAAGGGGAAATACTAAATCAAAAA
GCTAGTCAATTAAATTTGGAAGAGTTAGCAAAAAAAATAGGTGACGAAATGGTAAAAATAACTGGCGAAAGATGGTCTAC
TCCCTACAAAAAACCTGCCTTAGGTGCTATTTTCAAAAAGGCTATCATGGAGGTTACAAACTCAAGCGAAAAATTATGA

Upstream 100 bases:

>100_bases
ACGCTGTTGCCCAAGCAACAGGAAAAAGAATAAGATCCTTGCCCATAAACTTAGAGAAAATTGTTGTAGGTCATTCTTTG
AAAAAAGGAAGGAAGAAAAG

Downstream 100 bases:

>100_bases
TTTTGGTAAAGTGAGGTGTAACACATATGAACGAAGACATTCTAAAAGCAATAGATAAAGCTCTTAAAGAAGGACCTGAA
GGGGTTTTGTGTACAGTCGT

Product: FAD-binding molybdopterin dehydrogenase

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase FAD-subunit; NAH [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MIEYDFLIAKDVDSALEYLHKYENIKVLAGGTDILVDIHKESPRLEKFDYILDISNIKGLQYIDEMEDNVELGALCTHTM
LIQSNVINKYFPFLVTAAKSIGSVQIRNRGTVGGNISNASPAADLIPPLMALDSKIELSSINGKRHVPLDQYIVGPYKTS
KNQDELVTKIIIPKLDENYRFSFQKIGRRRALNIARLNLAVVAKINEQDSKIEDIRIVPGSATPFPIRFKNIEGEILNQK
ASQLNLEELAKKIGDEMVKITGERWSTPYKKPALGAIFKKAIMEVTNSSEKL

Sequences:

>Translated_292_residues
MIEYDFLIAKDVDSALEYLHKYENIKVLAGGTDILVDIHKESPRLEKFDYILDISNIKGLQYIDEMEDNVELGALCTHTM
LIQSNVINKYFPFLVTAAKSIGSVQIRNRGTVGGNISNASPAADLIPPLMALDSKIELSSINGKRHVPLDQYIVGPYKTS
KNQDELVTKIIIPKLDENYRFSFQKIGRRRALNIARLNLAVVAKINEQDSKIEDIRIVPGSATPFPIRFKNIEGEILNQK
ASQLNLEELAKKIGDEMVKITGERWSTPYKKPALGAIFKKAIMEVTNSSEKL
>Mature_292_residues
MIEYDFLIAKDVDSALEYLHKYENIKVLAGGTDILVDIHKESPRLEKFDYILDISNIKGLQYIDEMEDNVELGALCTHTM
LIQSNVINKYFPFLVTAAKSIGSVQIRNRGTVGGNISNASPAADLIPPLMALDSKIELSSINGKRHVPLDQYIVGPYKTS
KNQDELVTKIIIPKLDENYRFSFQKIGRRRALNIARLNLAVVAKINEQDSKIEDIRIVPGSATPFPIRFKNIEGEILNQK
ASQLNLEELAKKIGDEMVKITGERWSTPYKKPALGAIFKKAIMEVTNSSEKL

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=283, Percent_Identity=28.9752650176678, Blast_Score=131, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17540638, Length=177, Percent_Identity=31.0734463276836, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 32775; Mature: 32775

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYDFLIAKDVDSALEYLHKYENIKVLAGGTDILVDIHKESPRLEKFDYILDISNIKGL
CCEEEEEEEHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCCCCCHHHEEEEECCCCCH
QYIDEMEDNVELGALCTHTMLIQSNVINKYFPFLVTAAKSIGSVQIRNRGTVGGNISNAS
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCC
PAADLIPPLMALDSKIELSSINGKRHVPLDQYIVGPYKTSKNQDELVTKIIIPKLDENYR
CCHHHHHHHHHCCCCEEEEECCCCCCCCHHHEEECCCCCCCCHHHHHHHHHCCCCCCCCC
FSFQKIGRRRALNIARLNLAVVAKINEQDSKIEDIRIVPGSATPFPIRFKNIEGEILNQK
HHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCHHHHHH
ASQLNLEELAKKIGDEMVKITGERWSTPYKKPALGAIFKKAIMEVTNSSEKL
HHCCCHHHHHHHHCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIEYDFLIAKDVDSALEYLHKYENIKVLAGGTDILVDIHKESPRLEKFDYILDISNIKGL
CCEEEEEEEHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCCCCCHHHEEEEECCCCCH
QYIDEMEDNVELGALCTHTMLIQSNVINKYFPFLVTAAKSIGSVQIRNRGTVGGNISNAS
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCC
PAADLIPPLMALDSKIELSSINGKRHVPLDQYIVGPYKTSKNQDELVTKIIIPKLDENYR
CCHHHHHHHHHCCCCEEEEECCCCCCCCHHHEEECCCCCCCCHHHHHHHHHCCCCCCCCC
FSFQKIGRRRALNIARLNLAVVAKINEQDSKIEDIRIVPGSATPFPIRFKNIEGEILNQK
HHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCHHHHHH
ASQLNLEELAKKIGDEMVKITGERWSTPYKKPALGAIFKKAIMEVTNSSEKL
HHCCCHHHHHHHHCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA