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The map label for this gene is pucD [H]

Identifier: 160903167

GI number: 160903167

Start: 1897070

End: 1899262

Strand: Direct

Name: pucD [H]

Synonym: Pmob_1732

Alternate gene names: 160903167

Gene position: 1897070-1899262 (Clockwise)

Preceding gene: 160903166

Following gene: 160903168

Centisome position: 87.44

GC content: 37.71

Gene sequence:

>2193_bases
ATGTTGTATGCGAAGGTTCTGAGAACTAAGTATCCTTCGGCGAAAATATTGAACATAAACTTAGATGAAGCCGAAAAAAT
TCCTGGGGTAAAAGCAATTATTACCGCAAAAGATATACCAAATAACGAATTTGGTGTTATTATCCCAGACCAACAAGTTT
TAGCTAAAGAAAGGACTTATTTCATAGGTGATGGAATAGCCTTGGTCGCTGCAGAAACTCCTGAGACAGCAAAAAAAGCG
GTTGAAAGTATAAAAGTAGAATACATGGAGCTCCCTGGAATTTTTGATCCATTAGAGTCTAGAAATGCACCAACTATCCA
TGAAGATAAAGATAATAATCAGGTCATTCACCATAAACTTAGAAAAGGCGATGTAGAAGAAGGATTTAAAAGATCTGATG
TAATTTTGGAAAGAGAGTATCAAACCCAATTTGTTGAGCATGCATATTTAGAACCTGAGGTTGTAATTGCCGTTCCTTAT
GAAAACAACAGTGTGGTTACTATATATGGGTCTATACAAAACCCTTTTGCTTGTCGTAACGCAGTTGCCTCTGTTCTTAA
AATCGGATTCAACCAAGTTAGAATAGTTCAAAATCACATAGGAGGTTCGTTTGGTGGTAAAGATGAAGTAATTTCTTCTA
TGGCTGCTCGAGCTGCTGTTCTAGCTTTGAAAACGAATAGACCTGTAAAATTAAAAAATACTAGGGAAGAATCAATTATC
GAAAGTTATAAAAGGCATCCTTACAAACTGAAATACAAAGTCGGAGCAACAAAAGATGGCCAGTTACTGGCTATGGAAAT
TGAGGCAATCGCGGACAGCGGAGCTTACGCCTGCCAAACTCCATTTGTTACCTGGAGGTCTGTGGTTCAAGCTACTGGTC
CTTATGAAATTCCAAACGTTAAGACAGATACTTTTGGATACTATACCAACAATGTATACACTGGAGCCATGCGTGGATAC
GGTTCTCCTCAAGTTATATTTGCCAATGAATCTCTAATGGATGAATTAGCTCAAGAACTTGGGATGAATCCCTTGGAACT
TAGATTGAAAAATATTTTTCACGATAATTCTGTAACAGCAAGTGGCCAAAAACTTGATAATCACAAAGTCAGTCTCGGAG
AAGTGATTAAAAAGGCTACCGATTCGATCAATTTTTTAGAGAAATACAAAGAATACAGTAAGGAACAAAAAGGTGATAAA
CGGAAAGGAATAGGAATGGCTATAAGTTATAGAGGCTGTAGTTTAGGAGCAGAAGCTGTGGATGCCGCTGGTGTCATATT
ATCCATACAAAAAGATGGAACATTATATTTCTATAGTGGTTTGGCTGAAAACGGACAAGGTCTTAAAACAGCCTTCTCTC
AAATTGTAGCCGAGGAATTAGGAATAGATATTGAAAAGATCAACTTTATGGTCGTTGATACTTTGATATCTCCAGATAGC
GGTTCTACGGTGGCTTCTCGTGCGACATTGGTTGGTGGGAATGCAACGCTAGATGCCGCTAAAAAGCTCAAGAAGAAATT
AACTGATTTTCTTATAGAAAAATATAATTTATCCCACAAAGAATTAATATTTAAAGACAATTCGATTTATACTCCAAATC
AAATAAAATTAATGTCTTTCGATGAAGCTGTTTCCAGTGCATACAACTCTGGCGTCTTTTTATCTTCATATGGTTGGTAC
AAATCACCTGAGATAAGTTGGGATGAAGAAACAGGGCAAGGGAGACCCTATTTTACATATGTTTATGGATGTCAGATAGC
AGAAGTTGAAGTTGATATCAGCACTGGTGAGATAAAAGTTTTGAAAATGGTAGCTGCTCATGATGTTGGAAGAGCTATCA
ATCCTGCAAGCGTTCTTGGACAATTTTATGGTGGGATATCAATGGGCCTTGGATACGGAATCATGGAAGAGTTGGATACA
GACGAGGGATACATCAACAACACCAATTTTGACGAATATTTGATACCCACAGTAAAAGATATGCCAGATATAACTCCCAT
TATAGTTGAAAACCCTGATCCTAGTGGGCCTTACGGAGCAAAATCCGTAGGAGAGCCCACCTTAGAATTAGGTGCTGCTG
CTATAGCTAACGCTGTTGCCCAAGCAACAGGAAAAAGAATAAGATCCTTGCCCATAAACTTAGAGAAAATTGTTGTAGGT
CATTCTTTGAAAAAAGGAAGGAAGAAAAGATGA

Upstream 100 bases:

>100_bases
AATCATTTTTAAAACTGTTAATCAACCAAAAAAGAGAATAGACGCATACGAAAAGGTTACTGGAAAAGCTAAATTTGCAG
ATGATCTAGAATTTCCAAAT

Downstream 100 bases:

>100_bases
TTGAATATGATTTTTTAATTGCTAAAGATGTTGATTCTGCTTTAGAATATTTGCATAAATATGAAAATATAAAGGTATTA
GCTGGTGGAACTGATATACT

Product: xanthine dehydrogenase

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MLYAKVLRTKYPSAKILNINLDEAEKIPGVKAIITAKDIPNNEFGVIIPDQQVLAKERTYFIGDGIALVAAETPETAKKA
VESIKVEYMELPGIFDPLESRNAPTIHEDKDNNQVIHHKLRKGDVEEGFKRSDVILEREYQTQFVEHAYLEPEVVIAVPY
ENNSVVTIYGSIQNPFACRNAVASVLKIGFNQVRIVQNHIGGSFGGKDEVISSMAARAAVLALKTNRPVKLKNTREESII
ESYKRHPYKLKYKVGATKDGQLLAMEIEAIADSGAYACQTPFVTWRSVVQATGPYEIPNVKTDTFGYYTNNVYTGAMRGY
GSPQVIFANESLMDELAQELGMNPLELRLKNIFHDNSVTASGQKLDNHKVSLGEVIKKATDSINFLEKYKEYSKEQKGDK
RKGIGMAISYRGCSLGAEAVDAAGVILSIQKDGTLYFYSGLAENGQGLKTAFSQIVAEELGIDIEKINFMVVDTLISPDS
GSTVASRATLVGGNATLDAAKKLKKKLTDFLIEKYNLSHKELIFKDNSIYTPNQIKLMSFDEAVSSAYNSGVFLSSYGWY
KSPEISWDEETGQGRPYFTYVYGCQIAEVEVDISTGEIKVLKMVAAHDVGRAINPASVLGQFYGGISMGLGYGIMEELDT
DEGYINNTNFDEYLIPTVKDMPDITPIIVENPDPSGPYGAKSVGEPTLELGAAAIANAVAQATGKRIRSLPINLEKIVVG
HSLKKGRKKR

Sequences:

>Translated_730_residues
MLYAKVLRTKYPSAKILNINLDEAEKIPGVKAIITAKDIPNNEFGVIIPDQQVLAKERTYFIGDGIALVAAETPETAKKA
VESIKVEYMELPGIFDPLESRNAPTIHEDKDNNQVIHHKLRKGDVEEGFKRSDVILEREYQTQFVEHAYLEPEVVIAVPY
ENNSVVTIYGSIQNPFACRNAVASVLKIGFNQVRIVQNHIGGSFGGKDEVISSMAARAAVLALKTNRPVKLKNTREESII
ESYKRHPYKLKYKVGATKDGQLLAMEIEAIADSGAYACQTPFVTWRSVVQATGPYEIPNVKTDTFGYYTNNVYTGAMRGY
GSPQVIFANESLMDELAQELGMNPLELRLKNIFHDNSVTASGQKLDNHKVSLGEVIKKATDSINFLEKYKEYSKEQKGDK
RKGIGMAISYRGCSLGAEAVDAAGVILSIQKDGTLYFYSGLAENGQGLKTAFSQIVAEELGIDIEKINFMVVDTLISPDS
GSTVASRATLVGGNATLDAAKKLKKKLTDFLIEKYNLSHKELIFKDNSIYTPNQIKLMSFDEAVSSAYNSGVFLSSYGWY
KSPEISWDEETGQGRPYFTYVYGCQIAEVEVDISTGEIKVLKMVAAHDVGRAINPASVLGQFYGGISMGLGYGIMEELDT
DEGYINNTNFDEYLIPTVKDMPDITPIIVENPDPSGPYGAKSVGEPTLELGAAAIANAVAQATGKRIRSLPINLEKIVVG
HSLKKGRKKR
>Mature_730_residues
MLYAKVLRTKYPSAKILNINLDEAEKIPGVKAIITAKDIPNNEFGVIIPDQQVLAKERTYFIGDGIALVAAETPETAKKA
VESIKVEYMELPGIFDPLESRNAPTIHEDKDNNQVIHHKLRKGDVEEGFKRSDVILEREYQTQFVEHAYLEPEVVIAVPY
ENNSVVTIYGSIQNPFACRNAVASVLKIGFNQVRIVQNHIGGSFGGKDEVISSMAARAAVLALKTNRPVKLKNTREESII
ESYKRHPYKLKYKVGATKDGQLLAMEIEAIADSGAYACQTPFVTWRSVVQATGPYEIPNVKTDTFGYYTNNVYTGAMRGY
GSPQVIFANESLMDELAQELGMNPLELRLKNIFHDNSVTASGQKLDNHKVSLGEVIKKATDSINFLEKYKEYSKEQKGDK
RKGIGMAISYRGCSLGAEAVDAAGVILSIQKDGTLYFYSGLAENGQGLKTAFSQIVAEELGIDIEKINFMVVDTLISPDS
GSTVASRATLVGGNATLDAAKKLKKKLTDFLIEKYNLSHKELIFKDNSIYTPNQIKLMSFDEAVSSAYNSGVFLSSYGWY
KSPEISWDEETGQGRPYFTYVYGCQIAEVEVDISTGEIKVLKMVAAHDVGRAINPASVLGQFYGGISMGLGYGIMEELDT
DEGYINNTNFDEYLIPTVKDMPDITPIIVENPDPSGPYGAKSVGEPTLELGAAAIANAVAQATGKRIRSLPINLEKIVVG
HSLKKGRKKR

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=735, Percent_Identity=30.0680272108844, Blast_Score=318, Evalue=2e-86,
Organism=Homo sapiens, GI71773480, Length=722, Percent_Identity=29.5013850415512, Blast_Score=287, Evalue=3e-77,
Organism=Escherichia coli, GI1789230, Length=746, Percent_Identity=30.5630026809651, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI1789246, Length=786, Percent_Identity=27.9898218829517, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI1786478, Length=727, Percent_Identity=27.3727647867951, Blast_Score=192, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17540638, Length=692, Percent_Identity=29.7687861271676, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17539860, Length=710, Percent_Identity=25.2112676056338, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32566215, Length=699, Percent_Identity=25.035765379113, Blast_Score=165, Evalue=7e-41,
Organism=Drosophila melanogaster, GI17737937, Length=721, Percent_Identity=29.6809986130374, Blast_Score=275, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24647193, Length=727, Percent_Identity=26.2723521320495, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24647199, Length=708, Percent_Identity=24.4350282485876, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24647201, Length=702, Percent_Identity=23.9316239316239, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24647195, Length=721, Percent_Identity=23.994452149792, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24647197, Length=721, Percent_Identity=23.994452149792, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 80255; Mature: 80255

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYAKVLRTKYPSAKILNINLDEAEKIPGVKAIITAKDIPNNEFGVIIPDQQVLAKERTY
CCHHHHHHCCCCCCEEEEEECCHHHHCCCEEEEEEECCCCCCCCEEEECCHHHHHCCCCE
FIGDGIALVAAETPETAKKAVESIKVEYMELPGIFDPLESRNAPTIHEDKDNNQVIHHKL
EEECCEEEEEECCCHHHHHHHHHHHHHEEECCCCCCCHHCCCCCCCCCCCCCCHHHHHHH
RKGDVEEGFKRSDVILEREYQTQFVEHAYLEPEVVIAVPYENNSVVTIYGSIQNPFACRN
HCCCHHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCHHHHH
AVASVLKIGFNQVRIVQNHIGGSFGGKDEVISSMAARAAVLALKTNRPVKLKNTREESII
HHHHHHHHCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHEEEEEECCCCEEECCCHHHHHH
ESYKRHPYKLKYKVGATKDGQLLAMEIEAIADSGAYACQTPFVTWRSVVQATGPYEIPNV
HHHHCCCEEEEEEECCCCCCCEEEEEEEEHHCCCCCEECCCHHHHHHHHHCCCCCCCCCC
KTDTFGYYTNNVYTGAMRGYGSPQVIFANESLMDELAQELGMNPLELRLKNIFHDNSVTA
CCCCCEEEECCEEEEHHCCCCCCEEEEECHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
SGQKLDNHKVSLGEVIKKATDSINFLEKYKEYSKEQKGDKRKGIGMAISYRGCSLGAEAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHH
DAAGVILSIQKDGTLYFYSGLAENGQGLKTAFSQIVAEELGIDIEKINFMVVDTLISPDS
CCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEEEEECCCC
GSTVASRATLVGGNATLDAAKKLKKKLTDFLIEKYNLSHKELIFKDNSIYTPNQIKLMSF
CCCHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCEEEEEH
DEAVSSAYNSGVFLSSYGWYKSPEISWDEETGQGRPYFTYVYGCQIAEVEVDISTGEIKV
HHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCCCEEE
LKMVAAHDVGRAINPASVLGQFYGGISMGLGYGIMEELDTDEGYINNTNFDEYLIPTVKD
HHHHHHHHCCCCCCHHHHHHHHHCCHHHHCCHHHHHHCCCCCCEECCCCCCCEECCCHHC
MPDITPIIVENPDPSGPYGAKSVGEPTLELGAAAIANAVAQATGKRIRSLPINLEKIVVG
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEC
HSLKKGRKKR
CCHHCCCCCC
>Mature Secondary Structure
MLYAKVLRTKYPSAKILNINLDEAEKIPGVKAIITAKDIPNNEFGVIIPDQQVLAKERTY
CCHHHHHHCCCCCCEEEEEECCHHHHCCCEEEEEEECCCCCCCCEEEECCHHHHHCCCCE
FIGDGIALVAAETPETAKKAVESIKVEYMELPGIFDPLESRNAPTIHEDKDNNQVIHHKL
EEECCEEEEEECCCHHHHHHHHHHHHHEEECCCCCCCHHCCCCCCCCCCCCCCHHHHHHH
RKGDVEEGFKRSDVILEREYQTQFVEHAYLEPEVVIAVPYENNSVVTIYGSIQNPFACRN
HCCCHHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCHHHHH
AVASVLKIGFNQVRIVQNHIGGSFGGKDEVISSMAARAAVLALKTNRPVKLKNTREESII
HHHHHHHHCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHEEEEEECCCCEEECCCHHHHHH
ESYKRHPYKLKYKVGATKDGQLLAMEIEAIADSGAYACQTPFVTWRSVVQATGPYEIPNV
HHHHCCCEEEEEEECCCCCCCEEEEEEEEHHCCCCCEECCCHHHHHHHHHCCCCCCCCCC
KTDTFGYYTNNVYTGAMRGYGSPQVIFANESLMDELAQELGMNPLELRLKNIFHDNSVTA
CCCCCEEEECCEEEEHHCCCCCCEEEEECHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
SGQKLDNHKVSLGEVIKKATDSINFLEKYKEYSKEQKGDKRKGIGMAISYRGCSLGAEAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHH
DAAGVILSIQKDGTLYFYSGLAENGQGLKTAFSQIVAEELGIDIEKINFMVVDTLISPDS
CCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEEEEECCCC
GSTVASRATLVGGNATLDAAKKLKKKLTDFLIEKYNLSHKELIFKDNSIYTPNQIKLMSF
CCCHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCEEEEEH
DEAVSSAYNSGVFLSSYGWYKSPEISWDEETGQGRPYFTYVYGCQIAEVEVDISTGEIKV
HHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCCCEEE
LKMVAAHDVGRAINPASVLGQFYGGISMGLGYGIMEELDTDEGYINNTNFDEYLIPTVKD
HHHHHHHHCCCCCCHHHHHHHHHCCHHHHCCHHHHHHCCCCCCEECCCCCCCEECCCHHC
MPDITPIIVENPDPSGPYGAKSVGEPTLELGAAAIANAVAQATGKRIRSLPINLEKIVVG
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEC
HSLKKGRKKR
CCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]