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The map label for this gene is coaD

Identifier: 160903154

GI number: 160903154

Start: 1883244

End: 1883732

Strand: Direct

Name: coaD

Synonym: Pmob_1719

Alternate gene names: 160903154

Gene position: 1883244-1883732 (Clockwise)

Preceding gene: 160903153

Following gene: 160903155

Centisome position: 86.8

GC content: 31.49

Gene sequence:

>489_bases
ATGGGAATTAGGGACGCAGCTTATCCAGGAAGTTTCGATCCAATAACCTTTGGACACGTTAATATAGTGAAAAGATCGAT
TGAAAGATTTGACAATCTGTATGTTGTTGTTGTGAATAATCCGAACAAAAAGTATTTGTTTTCTCTCCAAGAAAGGATTG
AAATGGTAAAAAAAGATTTAGAGGATATACCAAATGTTATTGTTGAATCTTTTGACGGTCTGTTGGTAAATTACCTAAAA
GAGAAAAAAATTTATAATTTAATAAGAGGCTTAAGAGCGGTCAGTGATTACGAGTATGAACTTCAAATGGCAAACGCGAA
TCATATGCTTTTTCCTCAGTTAGAAATTTTTTTTCTCATGGCTGATACTGATTTCTCTTATATTTCTTCATCTATGATAA
AAGAAATTGCATCTTACAACGGAGATGTTAGTAAGTGGGTTTCTAAGTTCGTCGAATTGAAGTTAAAAGAAAAACTATTA
AAAAAATAG

Upstream 100 bases:

>100_bases
TTGCCGTTACTCCTGGACAATTTGCAACAATTTATGATGAAAGCGGTGTTGTTTTGGCTTCCGGTGTAATCAATATTAAA
GAAATGGGGGAAGTTTGATA

Downstream 100 bases:

>100_bases
TAATAAAACAATAATTTTCTTATTTTAATATTCAATTAATTGTGTTAAAATAAATTAGTTTTAGCCAACGGTTGAGATTT
CAAATACTCAAATTTATTAA

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MGIRDAAYPGSFDPITFGHVNIVKRSIERFDNLYVVVVNNPNKKYLFSLQERIEMVKKDLEDIPNVIVESFDGLLVNYLK
EKKIYNLIRGLRAVSDYEYELQMANANHMLFPQLEIFFLMADTDFSYISSSMIKEIASYNGDVSKWVSKFVELKLKEKLL
KK

Sequences:

>Translated_162_residues
MGIRDAAYPGSFDPITFGHVNIVKRSIERFDNLYVVVVNNPNKKYLFSLQERIEMVKKDLEDIPNVIVESFDGLLVNYLK
EKKIYNLIRGLRAVSDYEYELQMANANHMLFPQLEIFFLMADTDFSYISSSMIKEIASYNGDVSKWVSKFVELKLKEKLL
KK
>Mature_161_residues
GIRDAAYPGSFDPITFGHVNIVKRSIERFDNLYVVVVNNPNKKYLFSLQERIEMVKKDLEDIPNVIVESFDGLLVNYLKE
KKIYNLIRGLRAVSDYEYELQMANANHMLFPQLEIFFLMADTDFSYISSSMIKEIASYNGDVSKWVSKFVELKLKEKLLK
K

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=42.3076923076923, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_PETMO (A9BIS4)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001568735.1
- ProteinModelPortal:   A9BIS4
- SMR:   A9BIS4
- GeneID:   5757015
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_1719
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- BioCyc:   PMOB403833:PMOB_1719-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18889; Mature: 18758

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRDAAYPGSFDPITFGHVNIVKRSIERFDNLYVVVVNNPNKKYLFSLQERIEMVKKDL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
EDIPNVIVESFDGLLVNYLKEKKIYNLIRGLRAVSDYEYELQMANANHMLFPQLEIFFLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCEEEEEEE
ADTDFSYISSSMIKEIASYNGDVSKWVSKFVELKLKEKLLKK
ECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GIRDAAYPGSFDPITFGHVNIVKRSIERFDNLYVVVVNNPNKKYLFSLQERIEMVKKDL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
EDIPNVIVESFDGLLVNYLKEKKIYNLIRGLRAVSDYEYELQMANANHMLFPQLEIFFLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCEEEEEEE
ADTDFSYISSSMIKEIASYNGDVSKWVSKFVELKLKEKLLKK
ECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA