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The map label for this gene is tdk [H]

Identifier: 160902945

GI number: 160902945

Start: 1617959

End: 1618549

Strand: Direct

Name: tdk [H]

Synonym: Pmob_1500

Alternate gene names: 160902945

Gene position: 1617959-1618549 (Clockwise)

Preceding gene: 160902944

Following gene: 160902946

Centisome position: 74.58

GC content: 34.69

Gene sequence:

>591_bases
ATGGCAACAGGTAATTTAGTAGTAATTGTTGGACCTATGTATTCTGGCAAAACTTCCGAATTAATCTCTTTCATTGAAAT
TTACACACTTGGTAAAAAGAAAATAAAAGTCTTCAAACCTTTGTTAGATAACCGATACAATGAAACTTACATTGTATCCC
ACTCTAATACATCTGTTAAAGCCATTCCCATCAATAACTCCGCTGAAATTTTGCCTAAACTTGATGGAGACGAAAAAGCG
GTTTTTATAGATGAAATTCAGTTTCTAGACGAGCCTCTTAGAGAAGTTGTTGTCGAGATGATCAACTCTGGTAAGGATGT
TTATTGTGCTGGCTTGGATTTGAGTTATAAAAATAATCCATTCAAAGTTACTTCACTTCTAATGGCTCATGCAGACACGG
TAATTAAAAAGAAAGCCGTTTGCCATGAATGTGGGGAGTATAGAGGTACAATATCTTACAAGATTGTTGAAAATGGTGGA
GAAATAGATGTTGGGGGATTTGAAAAATATATCGCCGTCTGTAGAGATTGCTACTTGAAGTTGAATGAAAAAAAACAAAA
TCAAGATAAAAAACTGAAACAAGGGGGTTGA

Upstream 100 bases:

>100_bases
GGAATTGAAACATTGTGGAAAGAGTCTTTGGATGAGATTGATCAACTACTATCCGAAAAATTTAATTAAAACTAATGAAA
AAGGGATGTGAAACTTTAAT

Downstream 100 bases:

>100_bases
TCTATGAGAATTACAAGCATCTATGATAACACAGAATTAGCCAATAAAGTGAAAATCCCTTGGTTGGGCTATGGGACGTA
CAAAGCCCATGGAGATGAGT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MATGNLVVIVGPMYSGKTSELISFIEIYTLGKKKIKVFKPLLDNRYNETYIVSHSNTSVKAIPINNSAEILPKLDGDEKA
VFIDEIQFLDEPLREVVVEMINSGKDVYCAGLDLSYKNNPFKVTSLLMAHADTVIKKKAVCHECGEYRGTISYKIVENGG
EIDVGGFEKYIAVCRDCYLKLNEKKQNQDKKLKQGG

Sequences:

>Translated_196_residues
MATGNLVVIVGPMYSGKTSELISFIEIYTLGKKKIKVFKPLLDNRYNETYIVSHSNTSVKAIPINNSAEILPKLDGDEKA
VFIDEIQFLDEPLREVVVEMINSGKDVYCAGLDLSYKNNPFKVTSLLMAHADTVIKKKAVCHECGEYRGTISYKIVENGG
EIDVGGFEKYIAVCRDCYLKLNEKKQNQDKKLKQGG
>Mature_195_residues
ATGNLVVIVGPMYSGKTSELISFIEIYTLGKKKIKVFKPLLDNRYNETYIVSHSNTSVKAIPINNSAEILPKLDGDEKAV
FIDEIQFLDEPLREVVVEMINSGKDVYCAGLDLSYKNNPFKVTSLLMAHADTVIKKKAVCHECGEYRGTISYKIVENGGE
IDVGGFEKYIAVCRDCYLKLNEKKQNQDKKLKQGG

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=178, Percent_Identity=33.7078651685393, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17543396, Length=200, Percent_Identity=32.5, Blast_Score=104, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21907; Mature: 21775

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGNLVVIVGPMYSGKTSELISFIEIYTLGKKKIKVFKPLLDNRYNETYIVSHSNTSVK
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCEEE
AIPINNSAEILPKLDGDEKAVFIDEIQFLDEPLREVVVEMINSGKDVYCAGLDLSYKNNP
EEECCCCHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCC
FKVTSLLMAHADTVIKKKAVCHECGEYRGTISYKIVENGGEIDVGGFEKYIAVCRDCYLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHC
LNEKKQNQDKKLKQGG
CCCCCCCHHHHHCCCC
>Mature Secondary Structure 
ATGNLVVIVGPMYSGKTSELISFIEIYTLGKKKIKVFKPLLDNRYNETYIVSHSNTSVK
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCEEE
AIPINNSAEILPKLDGDEKAVFIDEIQFLDEPLREVVVEMINSGKDVYCAGLDLSYKNNP
EEECCCCHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCC
FKVTSLLMAHADTVIKKKAVCHECGEYRGTISYKIVENGGEIDVGGFEKYIAVCRDCYLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHC
LNEKKQNQDKKLKQGG
CCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]