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The map label for this gene is galE [C]

Identifier: 160902769

GI number: 160902769

Start: 1414126

End: 1415067

Strand: Direct

Name: galE [C]

Synonym: Pmob_1322

Alternate gene names: 160902769

Gene position: 1414126-1415067 (Clockwise)

Preceding gene: 160902755

Following gene: 160902770

Centisome position: 65.18

GC content: 35.88

Gene sequence:

>942_bases
ATGGCTGATAAAAACAAATATCGAATCCTCGTTACTGGAGGTGCAGGTTTCATAGGTTCAAACTTAGTTGATAGATTGAT
GAAAGAAGGCCATTCCGTAGTTGTTATCGATAATCTTTCCACAGGAAATGTAGAATTCTTGTCACCTATGGCTCTTTTTT
ATCAACAAGATATTAGAGATTATAATGTTTTGGAGAAAATATTTGAAACCCACAAGTTTGATTATGTTTTTCATTTGGCG
GCGCAGATCTCTGTTCCCGATTCTGTTAAAGACCCAAACTGGGACGCAGAAATCAATGTGATGGGTACTTTGAATTTATT
GAAATTATCCGTTAAGTATGACATAAAAAAGTTCATATTTTCTTCTACAGGCGGGGCTATTTACGGTGATAACGCTCCTA
TTCCCACTTCAGAAGATTATTGTCCACATCCTATTAGTCCGTATGCCATTTCAAAACTTGCTTGCGAAAAATACATCGAA
TTTTATTCACTCCAATATGATCTTAATTACACTATATTGAGATATGCGAACGTATATGGTCCCAAACAAACTCCAAAAGG
AGAAGCCGGGGTAGTAGCAATCTTTACACAAAATATGCTTGAAAAAAAAGAGATAGTTATTTACGGTGATGGAGAACAAG
TGCGGGATTTCGTACATGTTTTTGATGTCGTTGAAGCCAATTTTTTATCAATAAATAAAGCTGATAAAGAGACGATAAAT
ATCTCAACCAATAAGAAGACAACTGTAAACGAACTTTTTGAAGTGATGAAAAGGAAAACAGGGTATGAGAATGCCCCAGT
TTATAAGCCAGAAAGAGATGGGGATGTGAAGATAAGCTTACTTTCGAATGCGAAGGCAAAAAGTATTTTAGGATGGGAGC
CTAATTACGATTTAGAAAAAGGGGTGGAAAACACTATTGAGTGGTACACAACCTCTTTATGA

Upstream 100 bases:

>100_bases
TATAACACAAGGTCACAGGGCAAAGCCACCAACTTCTTTCCTTATGGGCGGGCTGCGGGGCGAAGGGGCGCTAAATCATT
ATTACTTTTGGAGGCAAAAT

Downstream 100 bases:

>100_bases
GATAATTAGACCGAAAAAGGTTGATGAGGTATTGGGTAACGAAAAGTTGAAAGAAATTCTTAAAACCTGGATAAAAAATA
AAAAGGTTAGATCTTTCATT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MADKNKYRILVTGGAGFIGSNLVDRLMKEGHSVVVIDNLSTGNVEFLSPMALFYQQDIRDYNVLEKIFETHKFDYVFHLA
AQISVPDSVKDPNWDAEINVMGTLNLLKLSVKYDIKKFIFSSTGGAIYGDNAPIPTSEDYCPHPISPYAISKLACEKYIE
FYSLQYDLNYTILRYANVYGPKQTPKGEAGVVAIFTQNMLEKKEIVIYGDGEQVRDFVHVFDVVEANFLSINKADKETIN
ISTNKKTTVNELFEVMKRKTGYENAPVYKPERDGDVKISLLSNAKAKSILGWEPNYDLEKGVENTIEWYTTSL

Sequences:

>Translated_313_residues
MADKNKYRILVTGGAGFIGSNLVDRLMKEGHSVVVIDNLSTGNVEFLSPMALFYQQDIRDYNVLEKIFETHKFDYVFHLA
AQISVPDSVKDPNWDAEINVMGTLNLLKLSVKYDIKKFIFSSTGGAIYGDNAPIPTSEDYCPHPISPYAISKLACEKYIE
FYSLQYDLNYTILRYANVYGPKQTPKGEAGVVAIFTQNMLEKKEIVIYGDGEQVRDFVHVFDVVEANFLSINKADKETIN
ISTNKKTTVNELFEVMKRKTGYENAPVYKPERDGDVKISLLSNAKAKSILGWEPNYDLEKGVENTIEWYTTSL
>Mature_312_residues
ADKNKYRILVTGGAGFIGSNLVDRLMKEGHSVVVIDNLSTGNVEFLSPMALFYQQDIRDYNVLEKIFETHKFDYVFHLAA
QISVPDSVKDPNWDAEINVMGTLNLLKLSVKYDIKKFIFSSTGGAIYGDNAPIPTSEDYCPHPISPYAISKLACEKYIEF
YSLQYDLNYTILRYANVYGPKQTPKGEAGVVAIFTQNMLEKKEIVIYGDGEQVRDFVHVFDVVEANFLSINKADKETINI
STNKKTTVNELFEVMKRKTGYENAPVYKPERDGDVKISLLSNAKAKSILGWEPNYDLEKGVENTIEWYTTSL

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=321, Percent_Identity=31.1526479750779, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI7657641, Length=322, Percent_Identity=34.472049689441, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=27.299703264095, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=27.299703264095, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=27.299703264095, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI116268111, Length=279, Percent_Identity=27.2401433691756, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI239745448, Length=284, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI310132178, Length=284, Percent_Identity=25, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI310113012, Length=284, Percent_Identity=25, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=29.5180722891566, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1788353, Length=341, Percent_Identity=30.791788856305, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI48994969, Length=336, Percent_Identity=30.6547619047619, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788589, Length=348, Percent_Identity=25.8620689655172, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788365, Length=329, Percent_Identity=23.1003039513678, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788366, Length=347, Percent_Identity=23.9193083573487, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790049, Length=253, Percent_Identity=27.6679841897233, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=29.4985250737463, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71982038, Length=341, Percent_Identity=29.3255131964809, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17539532, Length=320, Percent_Identity=27.5, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17568069, Length=324, Percent_Identity=30.2469135802469, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI115532424, Length=320, Percent_Identity=28.75, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI133901790, Length=325, Percent_Identity=27.3846153846154, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133901788, Length=325, Percent_Identity=27.3846153846154, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI133901786, Length=325, Percent_Identity=27.3846153846154, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17539422, Length=325, Percent_Identity=27.3846153846154, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17539424, Length=325, Percent_Identity=27.3846153846154, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17507723, Length=327, Percent_Identity=26.605504587156, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32566934, Length=316, Percent_Identity=23.4177215189873, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=29.2397660818713, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21356223, Length=318, Percent_Identity=31.4465408805031, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=27.4336283185841, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24667531, Length=315, Percent_Identity=22.8571428571429, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35415; Mature: 35283

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKNKYRILVTGGAGFIGSNLVDRLMKEGHSVVVIDNLSTGNVEFLSPMALFYQQDIRD
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCHH
YNVLEKIFETHKFDYVFHLAAQISVPDSVKDPNWDAEINVMGTLNLLKLSVKYDIKKFIF
HHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEEEEEEHHHHHHHHHH
SSTGGAIYGDNAPIPTSEDYCPHPISPYAISKLACEKYIEFYSLQYDLNYTILRYANVYG
HCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCEEEEEEEHHCC
PKQTPKGEAGVVAIFTQNMLEKKEIVIYGDGEQVRDFVHVFDVVEANFLSINKADKETIN
CCCCCCCCCCEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEEE
ISTNKKTTVNELFEVMKRKTGYENAPVYKPERDGDVKISLLSNAKAKSILGWEPNYDLEK
EECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCHHH
GVENTIEWYTTSL
HHHHHHHHEEECC
>Mature Secondary Structure 
ADKNKYRILVTGGAGFIGSNLVDRLMKEGHSVVVIDNLSTGNVEFLSPMALFYQQDIRD
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCHH
YNVLEKIFETHKFDYVFHLAAQISVPDSVKDPNWDAEINVMGTLNLLKLSVKYDIKKFIF
HHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEEEEEEHHHHHHHHHH
SSTGGAIYGDNAPIPTSEDYCPHPISPYAISKLACEKYIEFYSLQYDLNYTILRYANVYG
HCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCEEEEEEEHHCC
PKQTPKGEAGVVAIFTQNMLEKKEIVIYGDGEQVRDFVHVFDVVEANFLSINKADKETIN
CCCCCCCCCCEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEEE
ISTNKKTTVNELFEVMKRKTGYENAPVYKPERDGDVKISLLSNAKAKSILGWEPNYDLEK
EECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCHHH
GVENTIEWYTTSL
HHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]