Click here to switch to the map view.

The map label for this gene is sbm [H]

Identifier: 160902026

GI number: 160902026

Start: 605582

End: 605983

Strand: Direct

Name: sbm [H]

Synonym: Pmob_0550

Alternate gene names: 160902026

Gene position: 605582-605983 (Clockwise)

Preceding gene: 160902025

Following gene: 160902027

Centisome position: 27.91

GC content: 38.06

Gene sequence:

>402_bases
ATGAGTACAAGAATTCGTGTCTTAATAGCTAAACCAGGGCTCGATGGTCATGACCGAGGAGCTAAAGTTTTAGCAAGAGC
ACTAAGAGACGCCGGAATGGAAGTAATCTACACAGGCATAAGAAGAACTCCGGAAGAAATCGTTGAAGCAGCAATTCAAG
AAGATGTTGATTTAATTGGCTTATCTATACTTTCAGGTGCACACAAGAAGTTATGTCAAAAAATACTAAATTTACTAAAA
GAAAAGGAAGCTGATATTCCCGTTACCCTTGGTGGAATCATTCCGGAAGAAGATATCCCGCAACTAAAGGAAATGGGAAT
AATCGAAATTTTCACCCCAGGTACTTCATTAAAAGATATAATAGAGAAGGTGAAAGATATTGCAATGGGCAGAAAAGTAT
GA

Upstream 100 bases:

>100_bases
TTTATACAATGAGGGTGGGGAGCGGGGCAAAGGGGCGCTGACAGAAATTTTAGAGTTTTTAAAGTCAGCATTTACCATTT
GGAGAGGAGGCAGCTTTGAA

Downstream 100 bases:

>100_bases
ACAATTACTTCCAAAATTTAAAGCCCATAATAACACCGCTTTAGCAAAGATGATTTCTCTATTAGAAGACAATTATTCAC
AAACCTGGGAAATTATTTCT

Product: cobalamin B12-binding domain-containing protein

Products: succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MSTRIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGIRRTPEEIVEAAIQEDVDLIGLSILSGAHKKLCQKILNLLK
EKEADIPVTLGGIIPEEDIPQLKEMGIIEIFTPGTSLKDIIEKVKDIAMGRKV

Sequences:

>Translated_133_residues
MSTRIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGIRRTPEEIVEAAIQEDVDLIGLSILSGAHKKLCQKILNLLK
EKEADIPVTLGGIIPEEDIPQLKEMGIIEIFTPGTSLKDIIEKVKDIAMGRKV
>Mature_132_residues
STRIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGIRRTPEEIVEAAIQEDVDLIGLSILSGAHKKLCQKILNLLKE
KEADIPVTLGGIIPEEDIPQLKEMGIIEIFTPGTSLKDIIEKVKDIAMGRKV

Specific function: Unknown

COG id: COG2185

COG function: function code I; Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156105689, Length=126, Percent_Identity=39.6825396825397, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1789284, Length=125, Percent_Identity=43.2, Blast_Score=100, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25144500, Length=125, Percent_Identity=39.2, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006158
- InterPro:   IPR006099
- InterPro:   IPR006098 [H]

Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]

EC number: NA

Molecular weight: Translated: 14562; Mature: 14431

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGIRRTPEEIVEAAIQEDVDLIG
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LSILSGAHKKLCQKILNLLKEKEADIPVTLGGIIPEEDIPQLKEMGIIEIFTPGTSLKDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHCCEEEEECCCCCHHHH
IEKVKDIAMGRKV
HHHHHHHHHCCCC
>Mature Secondary Structure 
STRIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGIRRTPEEIVEAAIQEDVDLIG
CCEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LSILSGAHKKLCQKILNLLKEKEADIPVTLGGIIPEEDIPQLKEMGIIEIFTPGTSLKDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHCCEEEEECCCCCHHHH
IEKVKDIAMGRKV
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Co [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-methylmalonyl-CoA [C]

Specific reaction: L-methylmalonyl-CoA = succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1355087; 9278503 [H]