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The map label for this gene is murQ

Identifier: 160901963

GI number: 160901963

Start: 525268

End: 526164

Strand: Direct

Name: murQ

Synonym: Pmob_0485

Alternate gene names: 160901963

Gene position: 525268-526164 (Clockwise)

Preceding gene: 160901962

Following gene: 160901965

Centisome position: 24.21

GC content: 36.79

Gene sequence:

>897_bases
ATGCTAGAGAATCTGGAAACCGAAAAAAGTAACCCTAAGACTCAGAATTTGGACGAGATGGACATACATGAAATACTAAG
AATAATTAATCAAGAGGATGCAACAATAGCGTTATCCATCGCCGAAAATTTAGAGAATATAGAAAATGTGGTTGCCAACT
GTATTTCAGCTATTAAGAATCACGGAAGGATCATATATGTTGGGGCAGGGACGAGTGGTAGAGTGGCCGTTGTAGATGCG
GTAGAAACAGTTCCAACTTTTGGTATAGATTCCGGGATTTTTCTCCCCTTAATCGCGGGAGGAGAAAAAGCCTTCTTTCA
AGCTACAGAACATGTTGAAGATTACGAAGAAAGCGGGAAAAAAGACTTAGAAAAAAATAACGTCCGTTCTGAAGATTACG
TAATAGGGATAACTGCTAGCGGGCGAACCCCTTATGTAAAAGGTGCTTTATCTCTGGCAAAAGAAATAGGATGTAAAACT
GCTTTAATATGCAACGTAAAAAACCCTGAATTGATGGAATTTTCGGATATTGTAGTTTCTTTGAGAACGGGCCCAGAAGT
CATTGCAGGAAGTACAAGAATGAAAGCGGGCACAGCCCAAAAAATGGTTTTAAATATGATAAGCACTGTCACCATGATAA
AACTTGGAAAGACTTTTAAAAACTACATGGTGGACGTAAAAATCATGAATCAAAAATTAGAAGAAAGAGCAGTAAGAATA
ATTTCTGAGGTAACCGGATTAGATAAAAAAACCTGCAAAGAGTACTTAATCAAGGCTGATATGAAACCCAAATTGGCAAT
ACTGATGATTCTATCTGGAAAAGACAAAGAATTTTGTATCGAAGCTCTAAAGAAAAACGAAGTATTGCATGAAGCATTGA
AAACATTAAAGAATTAA

Upstream 100 bases:

>100_bases
ACATACGGTTTTAATGAAAATATTCAAACTTCTTTGCTTAAAATTCTCAAAGGAGAAATAAAACCAACTGGGAATTTACC
AATTAAACGGAGGCTAGAAA

Downstream 100 bases:

>100_bases
ACTCATAGGAAAATCCCCATATTTGGGGATTTTTTATCAAATTATATTTCATTTTCGTTTGAAAATTTCATACACTTGAT
CGATATTATAGGTATTTATC

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLENLETEKSNPKTQNLDEMDIHEILRIINQEDATIALSIAENLENIENVVANCISAIKNHGRIIYVGAGTSGRVAVVDA
VETVPTFGIDSGIFLPLIAGGEKAFFQATEHVEDYEESGKKDLEKNNVRSEDYVIGITASGRTPYVKGALSLAKEIGCKT
ALICNVKNPELMEFSDIVVSLRTGPEVIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTFKNYMVDVKIMNQKLEERAVRI
ISEVTGLDKKTCKEYLIKADMKPKLAILMILSGKDKEFCIEALKKNEVLHEALKTLKN

Sequences:

>Translated_298_residues
MLENLETEKSNPKTQNLDEMDIHEILRIINQEDATIALSIAENLENIENVVANCISAIKNHGRIIYVGAGTSGRVAVVDA
VETVPTFGIDSGIFLPLIAGGEKAFFQATEHVEDYEESGKKDLEKNNVRSEDYVIGITASGRTPYVKGALSLAKEIGCKT
ALICNVKNPELMEFSDIVVSLRTGPEVIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTFKNYMVDVKIMNQKLEERAVRI
ISEVTGLDKKTCKEYLIKADMKPKLAILMILSGKDKEFCIEALKKNEVLHEALKTLKN
>Mature_298_residues
MLENLETEKSNPKTQNLDEMDIHEILRIINQEDATIALSIAENLENIENVVANCISAIKNHGRIIYVGAGTSGRVAVVDA
VETVPTFGIDSGIFLPLIAGGEKAFFQATEHVEDYEESGKKDLEKNNVRSEDYVIGITASGRTPYVKGALSLAKEIGCKT
ALICNVKNPELMEFSDIVVSLRTGPEVIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTFKNYMVDVKIMNQKLEERAVRI
ISEVTGLDKKTCKEYLIKADMKPKLAILMILSGKDKEFCIEALKKNEVLHEALKTLKN

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=274, Percent_Identity=42.3357664233577, Blast_Score=217, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_PETMO (A9BFQ1)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001567544.1
- ProteinModelPortal:   A9BFQ1
- SMR:   A9BFQ1
- GeneID:   5757465
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_0485
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- ProtClustDB:   PRK05441
- BioCyc:   PMOB403833:PMOB_0485-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 32851; Mature: 32851

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 82-82 ACT_SITE 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENLETEKSNPKTQNLDEMDIHEILRIINQEDATIALSIAENLENIENVVANCISAIKN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
HGRIIYVGAGTSGRVAVVDAVETVPTFGIDSGIFLPLIAGGEKAFFQATEHVEDYEESGK
CCEEEEEECCCCCCEEEEEHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCH
KDLEKNNVRSEDYVIGITASGRTPYVKGALSLAKEIGCKTALICNVKNPELMEFSDIVVS
HHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHEE
LRTGPEVIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTFKNYMVDVKIMNQKLEERAVRI
ECCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISEVTGLDKKTCKEYLIKADMKPKLAILMILSGKDKEFCIEALKKNEVLHEALKTLKN
HHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLENLETEKSNPKTQNLDEMDIHEILRIINQEDATIALSIAENLENIENVVANCISAIKN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
HGRIIYVGAGTSGRVAVVDAVETVPTFGIDSGIFLPLIAGGEKAFFQATEHVEDYEESGK
CCEEEEEECCCCCCEEEEEHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCH
KDLEKNNVRSEDYVIGITASGRTPYVKGALSLAKEIGCKTALICNVKNPELMEFSDIVVS
HHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHEE
LRTGPEVIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTFKNYMVDVKIMNQKLEERAVRI
ECCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISEVTGLDKKTCKEYLIKADMKPKLAILMILSGKDKEFCIEALKKNEVLHEALKTLKN
HHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA