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The map label for this gene is regA [H]

Identifier: 160901551

GI number: 160901551

Start: 55067

End: 56134

Strand: Direct

Name: regA [H]

Synonym: Pmob_0060

Alternate gene names: 160901551

Gene position: 55067-56134 (Clockwise)

Preceding gene: 160901546

Following gene: 160901552

Centisome position: 2.54

GC content: 33.52

Gene sequence:

>1068_bases
TTGCCCCTTAATGTAGGGCTGAAGCTCCGCTATATATATAATTATGATTCCGAGGTGAATATTGTGAAAGAGAAAAAGAG
AAATCCAAATCCCACTATTAAAGACGTAGCACGACTCGCCAACGTTGGAATAGCAACAGTTTCAAGGGTATTAAATAATT
CCGAAAAGGTAAGCGAAAAGACAAAAGAGAAAGTTCTAGAAATCATAGAAGAGTTGGGATATTCTCCCAACATTAACGCT
AGAACATTATCTTCAAAAAATATAAATTCTCTTTCTTTTGTAACACCAGACATGGGAAACGAATTTTATGGAATCATGTA
TTCTCTACTTGAAAAGAAAATTTCTCGAAATAATTATAGGTTGATTGTTTTTCCCCTCATAGATCAGATATCTCTGGAAA
AGATTAAGCAAAATACTGATCTAATTTATCAAACCGATGGTGTGTTTATCTCTTCTCTTTCCGTTTCAAGTATTTTTCAT
AACAGAATTCCCCCTAAGAAAATAATATTGATCGATTCATATGATGAGAGATTCGATTCTGTTTACGTTGATAATTATCA
AGTCGGGAAAACAGCCGCTCAATATCTCATAAATAATTCACCTGCAAATAGTACTTTCTATTTAGTTACTTTTAAGGAGC
TCAACAATGAATTTACCTCTTTCGTCTTCAAAAAAAGAGACGAAGGTTTTTTAGAAGTTATGGAAGAGAACAATAAAAAG
GTAAAGATTATATATAGCGATTTATTGTGGGATGGGGGGTATAAAGCGATTGGAACCCTTATAAAAAGGCGCCCCAGAAA
ATATTCATCCATTTTTGCAACATGTGACATGATTGGAGTAGGTGTCAAAAAATACTTGGAAGAAATGAATATGTATCCAA
AAAAGGATTATTCATTGATAGCTGTTGACAATCTTCCTATTAGTAGGCTATTTCAATTAACAACGATTAGACAACCGATT
AGCGAAATGGTCGAAATTGCTTATGAGATGTTCGTCTCTTCCATGGAAGGAAGAGAAAAAGCTGAACATTACAAATTGGA
AGCCAAAATAGTAGAAAGAGAAACATAG

Upstream 100 bases:

>100_bases
AGTTTTATGCAAAATGGTTTTTTTCGTAATGTTTTTGAATAACTTTCCTAATCTCATTTGCTTTGCAAATGATGTATTGA
ATTCGGGGTTTTTAAGGGGC

Downstream 100 bases:

>100_bases
AAGATATTATTATTTTTTTCTATATTGTGGAAACCTTTTCACTATATCACAACTTCAAAAGGAGGTCGGTATTTATGAGG
AAAGTAGGTTACTTTTTGCT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MPLNVGLKLRYIYNYDSEVNIVKEKKRNPNPTIKDVARLANVGIATVSRVLNNSEKVSEKTKEKVLEIIEELGYSPNINA
RTLSSKNINSLSFVTPDMGNEFYGIMYSLLEKKISRNNYRLIVFPLIDQISLEKIKQNTDLIYQTDGVFISSLSVSSIFH
NRIPPKKIILIDSYDERFDSVYVDNYQVGKTAAQYLINNSPANSTFYLVTFKELNNEFTSFVFKKRDEGFLEVMEENNKK
VKIIYSDLLWDGGYKAIGTLIKRRPRKYSSIFATCDMIGVGVKKYLEEMNMYPKKDYSLIAVDNLPISRLFQLTTIRQPI
SEMVEIAYEMFVSSMEGREKAEHYKLEAKIVERET

Sequences:

>Translated_355_residues
MPLNVGLKLRYIYNYDSEVNIVKEKKRNPNPTIKDVARLANVGIATVSRVLNNSEKVSEKTKEKVLEIIEELGYSPNINA
RTLSSKNINSLSFVTPDMGNEFYGIMYSLLEKKISRNNYRLIVFPLIDQISLEKIKQNTDLIYQTDGVFISSLSVSSIFH
NRIPPKKIILIDSYDERFDSVYVDNYQVGKTAAQYLINNSPANSTFYLVTFKELNNEFTSFVFKKRDEGFLEVMEENNKK
VKIIYSDLLWDGGYKAIGTLIKRRPRKYSSIFATCDMIGVGVKKYLEEMNMYPKKDYSLIAVDNLPISRLFQLTTIRQPI
SEMVEIAYEMFVSSMEGREKAEHYKLEAKIVERET
>Mature_354_residues
PLNVGLKLRYIYNYDSEVNIVKEKKRNPNPTIKDVARLANVGIATVSRVLNNSEKVSEKTKEKVLEIIEELGYSPNINAR
TLSSKNINSLSFVTPDMGNEFYGIMYSLLEKKISRNNYRLIVFPLIDQISLEKIKQNTDLIYQTDGVFISSLSVSSIFHN
RIPPKKIILIDSYDERFDSVYVDNYQVGKTAAQYLINNSPANSTFYLVTFKELNNEFTSFVFKKRDEGFLEVMEENNKKV
KIIYSDLLWDGGYKAIGTLIKRRPRKYSSIFATCDMIGVGVKKYLEEMNMYPKKDYSLIAVDNLPISRLFQLTTIRQPIS
EMVEIAYEMFVSSMEGREKAEHYKLEAKIVERET

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788474, Length=327, Percent_Identity=26.2996941896024, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787948, Length=344, Percent_Identity=26.453488372093, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789202, Length=319, Percent_Identity=26.9592476489028, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=25.2396166134185, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790369, Length=336, Percent_Identity=24.1071428571429, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1789068, Length=340, Percent_Identity=24.7058823529412, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786268, Length=223, Percent_Identity=29.1479820627803, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790689, Length=326, Percent_Identity=22.0858895705521, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787580, Length=336, Percent_Identity=25.8928571428571, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787906, Length=176, Percent_Identity=30.1136363636364, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790715, Length=324, Percent_Identity=24.6913580246914, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 41012; Mature: 40881

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNVGLKLRYIYNYDSEVNIVKEKKRNPNPTIKDVARLANVGIATVSRVLNNSEKVSEK
CCCCCCEEEEEEEECCCCEEHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHCCHHHHHHH
TKEKVLEIIEELGYSPNINARTLSSKNINSLSFVTPDMGNEFYGIMYSLLEKKISRNNYR
HHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCE
LIVFPLIDQISLEKIKQNTDLIYQTDGVFISSLSVSSIFHNRIPPKKIILIDSYDERFDS
EEEEECCCHHHHHHHHCCCCEEEEECCEEEEHHHHHHHHHCCCCCCEEEEEECCCCHHCE
VYVDNYQVGKTAAQYLINNSPANSTFYLVTFKELNNEFTSFVFKKRDEGFLEVMEENNKK
EEECCEEHHHHHHHHHHCCCCCCCEEEEEEHHHHCCHHHHHHHHCCCCHHHHHHHCCCCE
VKIIYSDLLWDGGYKAIGTLIKRRPRKYSSIFATCDMIGVGVKKYLEEMNMYPKKDYSLI
EEEEEEEHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
AVDNLPISRLFQLTTIRQPISEMVEIAYEMFVSSMEGREKAEHYKLEAKIVERET
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEEEEECCCC
>Mature Secondary Structure 
PLNVGLKLRYIYNYDSEVNIVKEKKRNPNPTIKDVARLANVGIATVSRVLNNSEKVSEK
CCCCCEEEEEEEECCCCEEHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHCCHHHHHHH
TKEKVLEIIEELGYSPNINARTLSSKNINSLSFVTPDMGNEFYGIMYSLLEKKISRNNYR
HHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCE
LIVFPLIDQISLEKIKQNTDLIYQTDGVFISSLSVSSIFHNRIPPKKIILIDSYDERFDS
EEEEECCCHHHHHHHHCCCCEEEEECCEEEEHHHHHHHHHCCCCCCEEEEEECCCCHHCE
VYVDNYQVGKTAAQYLINNSPANSTFYLVTFKELNNEFTSFVFKKRDEGFLEVMEENNKK
EEECCEEHHHHHHHHHHCCCCCCCEEEEEEHHHHCCHHHHHHHHCCCCHHHHHHHCCCCE
VKIIYSDLLWDGGYKAIGTLIKRRPRKYSSIFATCDMIGVGVKKYLEEMNMYPKKDYSLI
EEEEEEEHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
AVDNLPISRLFQLTTIRQPISEMVEIAYEMFVSSMEGREKAEHYKLEAKIVERET
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]