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The map label for this gene is glpG [H]

Identifier: 160877584

GI number: 160877584

Start: 5294804

End: 5295649

Strand: Direct

Name: glpG [H]

Synonym: Sbal195_4483

Alternate gene names: 160877584

Gene position: 5294804-5295649 (Clockwise)

Preceding gene: 160877583

Following gene: 160877586

Centisome position: 99.02

GC content: 50.24

Gene sequence:

>846_bases
ATGATAGAAATTGGCCGACTCCCCAACAGTAGAGCCGCGCAGGCATTTGTCGATTACCTCAAAGGTGAACACATTGACTG
CCAAATTGAGCCGCTGGAGCAAGGTGTCGCCATTCTCGTCATCCATGACAAAGATCTGGAGCAAGCGCGCACAGAGTTTG
CCCATTTCATGGCTCATCCCTACGACAGTAAATATCTGCAAGCCTCGTGGGAACACGGCGATACCCAAACTAAGATAGAT
TACGGCGCCCCTTCGCTACAGTTGTTTACCCAATTCATTACCGGCGCTGGCCCAGTCACGTTGATCGTTTTTGCGGTTTG
TGTACTCATTTTTGCGGCGATGAACTTAGGGTTCGCCAACCAAACCTACGCGGCACTGTCCTATTTTGGCGCGGTACCAA
ATTCAGAGTTCAGCCAGTTCTGGCGCGTTTTCACTCCGAGCCTGCTGCACTTTTCGGCCATGCACGTCATCTTTAACTTG
CTTTGGTGGTGGTATTTAGGCGGAAAAATCGAAACCCGAATCGGCACAGCACCATTGCTAATCTTGCTGTTTGTGGCGGG
CACACTGCCAAACGTCATCCAATATTATGTCGGTGGACCTAACTTCGGCGGGCTATCTGGCGTTGTGTATGCCGTGGTGG
GTTACACTTGGGTCATGGGGATACGTAAACCTACTGCTGGAATAGACTTTCCACCATCATATATGGCCTTTATGATGATT
TGGTTGGCATTGGGATTCACGGATATTCTAGGGGTTGCCGTTGCGAACGGTGCCCACATTGGTGGCTTACTCATAGGGTT
AGCCCAAGGTTTATTCGATAGCCGCAAGTCCTCAAGCTCAGTCTAA

Upstream 100 bases:

>100_bases
GTATGAGCAGCCAAAATGCGGCGCAGTATTTATGCGAGCAAGGGTTTGATGACGTTTACAGTCTAGACGGCGGCTATAGC
GCCTGGCATGAGGCAAATGC

Downstream 100 bases:

>100_bases
TCCCGTTATACCAAGATAAATCCAGAAGAACGCATGGGGATTTATCTTGGTTCAATGACGTGCTCTTACACTTCTACAAA
CCTAACGCGCGTCAGTCATC

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MIEIGRLPNSRAAQAFVDYLKGEHIDCQIEPLEQGVAILVIHDKDLEQARTEFAHFMAHPYDSKYLQASWEHGDTQTKID
YGAPSLQLFTQFITGAGPVTLIVFAVCVLIFAAMNLGFANQTYAALSYFGAVPNSEFSQFWRVFTPSLLHFSAMHVIFNL
LWWWYLGGKIETRIGTAPLLILLFVAGTLPNVIQYYVGGPNFGGLSGVVYAVVGYTWVMGIRKPTAGIDFPPSYMAFMMI
WLALGFTDILGVAVANGAHIGGLLIGLAQGLFDSRKSSSSV

Sequences:

>Translated_281_residues
MIEIGRLPNSRAAQAFVDYLKGEHIDCQIEPLEQGVAILVIHDKDLEQARTEFAHFMAHPYDSKYLQASWEHGDTQTKID
YGAPSLQLFTQFITGAGPVTLIVFAVCVLIFAAMNLGFANQTYAALSYFGAVPNSEFSQFWRVFTPSLLHFSAMHVIFNL
LWWWYLGGKIETRIGTAPLLILLFVAGTLPNVIQYYVGGPNFGGLSGVVYAVVGYTWVMGIRKPTAGIDFPPSYMAFMMI
WLALGFTDILGVAVANGAHIGGLLIGLAQGLFDSRKSSSSV
>Mature_281_residues
MIEIGRLPNSRAAQAFVDYLKGEHIDCQIEPLEQGVAILVIHDKDLEQARTEFAHFMAHPYDSKYLQASWEHGDTQTKID
YGAPSLQLFTQFITGAGPVTLIVFAVCVLIFAAMNLGFANQTYAALSYFGAVPNSEFSQFWRVFTPSLLHFSAMHVIFNL
LWWWYLGGKIETRIGTAPLLILLFVAGTLPNVIQYYVGGPNFGGLSGVVYAVVGYTWVMGIRKPTAGIDFPPSYMAFMMI
WLALGFTDILGVAVANGAHIGGLLIGLAQGLFDSRKSSSSV

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=274, Percent_Identity=39.7810218978102, Blast_Score=211, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 30842; Mature: 30842

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIGRLPNSRAAQAFVDYLKGEHIDCQIEPLEQGVAILVIHDKDLEQARTEFAHFMAHP
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHCC
YDSKYLQASWEHGDTQTKIDYGAPSLQLFTQFITGAGPVTLIVFAVCVLIFAAMNLGFAN
CCCHHHEECCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
QTYAALSYFGAVPNSEFSQFWRVFTPSLLHFSAMHVIFNLLWWWYLGGKIETRIGTAPLL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHH
ILLFVAGTLPNVIQYYVGGPNFGGLSGVVYAVVGYTWVMGIRKPTAGIDFPPSYMAFMMI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
WLALGFTDILGVAVANGAHIGGLLIGLAQGLFDSRKSSSSV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIEIGRLPNSRAAQAFVDYLKGEHIDCQIEPLEQGVAILVIHDKDLEQARTEFAHFMAHP
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHCC
YDSKYLQASWEHGDTQTKIDYGAPSLQLFTQFITGAGPVTLIVFAVCVLIFAAMNLGFAN
CCCHHHEECCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
QTYAALSYFGAVPNSEFSQFWRVFTPSLLHFSAMHVIFNLLWWWYLGGKIETRIGTAPLL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHH
ILLFVAGTLPNVIQYYVGGPNFGGLSGVVYAVVGYTWVMGIRKPTAGIDFPPSYMAFMMI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
WLALGFTDILGVAVANGAHIGGLLIGLAQGLFDSRKSSSSV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA