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The map label for this gene is irgA [H]

Identifier: 160877343

GI number: 160877343

Start: 5018662

End: 5020662

Strand: Reverse

Name: irgA [H]

Synonym: Sbal195_4241

Alternate gene names: 160877343

Gene position: 5020662-5018662 (Counterclockwise)

Preceding gene: 160877346

Following gene: 160877340

Centisome position: 93.89

GC content: 49.58

Gene sequence:

>2001_bases
ATGTTGTTAAGTCGTAAGAAGTACCTCGCTCAAGTGATCACCGCTTTATGTTTGTTGCCCGCAGTACCTGTGACAAATGC
CCTTGCGGATACAGCGTCTGATAAAGAAAAGATGATGGAAAGAATCGTAGTGACCGCATCGGGATTTGAACAACAAATTC
GCGACGCGCCCGCATCTATCAGTGTGATCACCCGTGAGGATCTGGATAACCGCTTCTATCGCGACTTAACCGATGCCATG
TTAGAAGTCCCCGGTGTAGTGATTACCGGCGGCGCTGACCGTCAGGACATCAGCCTGCGGGGCATGGGCAGCCAATACAC
GTTAATTTTAGTGGATGGTAAACGCCAATCTTCGCGCGAGACACGTACTAACAGCGACGGTCCAGGTGTTGAAGGCGCTT
GGACGCCACCATTGGCGGCCATTGATAGAATTGAAATTGTTCGCGGGCCTATGTCATCACTTTATGGTTCGGATGCCATT
GGCGGCGTGATCAACATTATCACTCGTAAAGTGCCGAATGAGTGGCAGGGTGAAGTGCGACTCGACACGACATTGCAGGA
AAAGTCGACCTCGGGAAATGTGTACCAGAGTAACTTTTTCGTTAACGGTGGCTTGATTAAAGATCTGCTGGGGATGCAAC
TTTACGGTCAATATACTCAGCGTGAAGAAGATAATATCTATGGCGGTTACCGTGGCCGTGATGCGACGAATCTGACCGCG
CGTTTTGCGCTCACCCCCAATGAAAACCACGACATCATGCTCGAAGTTGGGGTGTCAAACCAAGAACTCGACAGCAGCTT
AGGCAAAACCGTTACACCGCTGGCACCGGGCGAAGCCTGTGGTCGTCGCGGTTGTCCTCAATCTTCAACGACAGAATACG
AAAACAGCACCATTTCGCTTTCACACACAGGGCGTTGGGACTTTGGTACCTCGGATTCTTATATCAAGCATGAGGTTTTT
GATAACAAAACCCGCAAGATGAAGATCACTAACACGGATGTGCAATCTAGCCTGATCACCACCTTAGGCCAAAGCCATAC
GGCGACTTTTGGTGCGGCATTTAACCATCAAGATTTAACCGACGAAACCGGCAATCAGGTTAGCGACTTAACCGATATCA
GCCGCAGACAATGGTCGGTATTTTCTGAGGATGAATGGCGCATAGTCGATAACTTTGCCCTGACCATGGGGCTGCGTTTG
GATGATGATGAAAATTTTGGTCACCATGTCAGCCCGCGTGTTTACGGCGTGTGGGGATTAACCGACAGCACCACCTTAAA
GGGCGGCGTGTCGACGGGCTTTAGGGCGCCGAGTTTGCGCCAGACAGTGCCCGATTGGGGACAAGTGAGCCGTGGCGGCA
ACATGTACGGTAATCCAGATTTACAACCCGAAACCTCAGTGAACTATGAGTTAGGTGTGTATTCGGATCTGACCGAGAGC
ATTACCGCCAGTGCGGGTGTGTTCTATAACGAGTTTAAAGATAAGATCACCCGCGTGGCCTGTCCTGCGACTCAATGTAC
CGATGGTCCCAATCAATTTGGTTCCGACCCAACCACTTACGTGAATATCGACGATGCTGTGACTCAAGGGATTGAGTTGA
GTATCGACTATCGGATTCGCTCAAACCTGAGCTTTACGGGTAACTACACTTACACGGATTCAGAGCAAAAGACGGGTGCT
TACAAAGGTAGCCCATTGAATCAATTGCCTAAGCATTTGATCCAAGCGTCGTTCAACTACGAGCCTATTGATAACTTAAG
CACTTGGTTGAGAGTGAACTACCGTGGCGAAGAGAGCCAACCGACGACGGGACCGTCGTCGAGCAGTTTTATCGCACCTT
CTTACACTCTGCTGGATTTAGGGGCTAACTATCAGTTGAACGATAGCCTGAAATTTAGCGCGGGCATTTACAACGCCTTC
GATAAGGACATTACCCAAGAGGAATACGGTTATCTTGAAGATGGTCGCCGTTACTGGTTAGGTATGACCTACAGTTTTTA
A

Upstream 100 bases:

>100_bases
TACCTAAAGTCTAACTTGAGCTGATTGTAACATAGGGATACATTGCCGTATTGAAAATTGTTCTCATTTACAATCTTTGT
CCAATGGAGACTTGTCGGTT

Downstream 100 bases:

>100_bases
GCCGATACCTTATTGCTAACACTGAAACGAAAGCCAGAGTATTGACTCTGGCTTTTTGTTAGTTGTATTCATCAATAGGA
ATGACTATTCGTTTGCTAGC

Product: enterobactin receptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MLLSRKKYLAQVITALCLLPAVPVTNALADTASDKEKMMERIVVTASGFEQQIRDAPASISVITREDLDNRFYRDLTDAM
LEVPGVVITGGADRQDISLRGMGSQYTLILVDGKRQSSRETRTNSDGPGVEGAWTPPLAAIDRIEIVRGPMSSLYGSDAI
GGVINIITRKVPNEWQGEVRLDTTLQEKSTSGNVYQSNFFVNGGLIKDLLGMQLYGQYTQREEDNIYGGYRGRDATNLTA
RFALTPNENHDIMLEVGVSNQELDSSLGKTVTPLAPGEACGRRGCPQSSTTEYENSTISLSHTGRWDFGTSDSYIKHEVF
DNKTRKMKITNTDVQSSLITTLGQSHTATFGAAFNHQDLTDETGNQVSDLTDISRRQWSVFSEDEWRIVDNFALTMGLRL
DDDENFGHHVSPRVYGVWGLTDSTTLKGGVSTGFRAPSLRQTVPDWGQVSRGGNMYGNPDLQPETSVNYELGVYSDLTES
ITASAGVFYNEFKDKITRVACPATQCTDGPNQFGSDPTTYVNIDDAVTQGIELSIDYRIRSNLSFTGNYTYTDSEQKTGA
YKGSPLNQLPKHLIQASFNYEPIDNLSTWLRVNYRGEESQPTTGPSSSSFIAPSYTLLDLGANYQLNDSLKFSAGIYNAF
DKDITQEEYGYLEDGRRYWLGMTYSF

Sequences:

>Translated_666_residues
MLLSRKKYLAQVITALCLLPAVPVTNALADTASDKEKMMERIVVTASGFEQQIRDAPASISVITREDLDNRFYRDLTDAM
LEVPGVVITGGADRQDISLRGMGSQYTLILVDGKRQSSRETRTNSDGPGVEGAWTPPLAAIDRIEIVRGPMSSLYGSDAI
GGVINIITRKVPNEWQGEVRLDTTLQEKSTSGNVYQSNFFVNGGLIKDLLGMQLYGQYTQREEDNIYGGYRGRDATNLTA
RFALTPNENHDIMLEVGVSNQELDSSLGKTVTPLAPGEACGRRGCPQSSTTEYENSTISLSHTGRWDFGTSDSYIKHEVF
DNKTRKMKITNTDVQSSLITTLGQSHTATFGAAFNHQDLTDETGNQVSDLTDISRRQWSVFSEDEWRIVDNFALTMGLRL
DDDENFGHHVSPRVYGVWGLTDSTTLKGGVSTGFRAPSLRQTVPDWGQVSRGGNMYGNPDLQPETSVNYELGVYSDLTES
ITASAGVFYNEFKDKITRVACPATQCTDGPNQFGSDPTTYVNIDDAVTQGIELSIDYRIRSNLSFTGNYTYTDSEQKTGA
YKGSPLNQLPKHLIQASFNYEPIDNLSTWLRVNYRGEESQPTTGPSSSSFIAPSYTLLDLGANYQLNDSLKFSAGIYNAF
DKDITQEEYGYLEDGRRYWLGMTYSF
>Mature_666_residues
MLLSRKKYLAQVITALCLLPAVPVTNALADTASDKEKMMERIVVTASGFEQQIRDAPASISVITREDLDNRFYRDLTDAM
LEVPGVVITGGADRQDISLRGMGSQYTLILVDGKRQSSRETRTNSDGPGVEGAWTPPLAAIDRIEIVRGPMSSLYGSDAI
GGVINIITRKVPNEWQGEVRLDTTLQEKSTSGNVYQSNFFVNGGLIKDLLGMQLYGQYTQREEDNIYGGYRGRDATNLTA
RFALTPNENHDIMLEVGVSNQELDSSLGKTVTPLAPGEACGRRGCPQSSTTEYENSTISLSHTGRWDFGTSDSYIKHEVF
DNKTRKMKITNTDVQSSLITTLGQSHTATFGAAFNHQDLTDETGNQVSDLTDISRRQWSVFSEDEWRIVDNFALTMGLRL
DDDENFGHHVSPRVYGVWGLTDSTTLKGGVSTGFRAPSLRQTVPDWGQVSRGGNMYGNPDLQPETSVNYELGVYSDLTES
ITASAGVFYNEFKDKITRVACPATQCTDGPNQFGSDPTTYVNIDDAVTQGIELSIDYRIRSNLSFTGNYTYTDSEQKTGA
YKGSPLNQLPKHLIQASFNYEPIDNLSTWLRVNYRGEESQPTTGPSSSSFIAPSYTLLDLGANYQLNDSLKFSAGIYNAF
DKDITQEEYGYLEDGRRYWLGMTYSF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=697, Percent_Identity=37.0157819225251, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI1786798, Length=700, Percent_Identity=28.4285714285714, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI1790405, Length=162, Percent_Identity=35.8024691358025, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 73698; Mature: 73698

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSRKKYLAQVITALCLLPAVPVTNALADTASDKEKMMERIVVTASGFEQQIRDAPASI
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHEEECCCHHHHHHCCCCEE
SVITREDLDNRFYRDLTDAMLEVPGVVITGGADRQDISLRGMGSQYTLILVDGKRQSSRE
EEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCEEEEEEEECCCCCCHH
TRTNSDGPGVEGAWTPPLAAIDRIEIVRGPMSSLYGSDAIGGVINIITRKVPNEWQGEVR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCEE
LDTTLQEKSTSGNVYQSNFFVNGGLIKDLLGMQLYGQYTQREEDNIYGGYRGRDATNLTA
EEEEHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
RFALTPNENHDIMLEVGVSNQELDSSLGKTVTPLAPGEACGRRGCPQSSTTEYENSTISL
EEEECCCCCCEEEEEECCCCHHHHHHHCCEECCCCCCHHHCCCCCCCCCCCCCCCCEEEE
SHTGRWDFGTSDSYIKHEVFDNKTRKMKITNTDVQSSLITTLGQSHTATFGAAFNHQDLT
EECCCCCCCCCCCCEEHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCC
DETGNQVSDLTDISRRQWSVFSEDEWRIVDNFALTMGLRLDDDENFGHHVSPRVYGVWGL
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCEEEEEEEC
TDSTTLKGGVSTGFRAPSLRQTVPDWGQVSRGGNMYGNPDLQPETSVNYELGVYSDLTES
CCCCEECCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCEEECCHHHHHHH
ITASAGVFYNEFKDKITRVACPATQCTDGPNQFGSDPTTYVNIDDAVTQGIELSIDYRIR
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCEEEECHHHHHCCEEEEEEEEEE
SNLSFTGNYTYTDSEQKTGAYKGSPLNQLPKHLIQASFNYEPIDNLSTWLRVNYRGEESQ
CCEEEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
PTTGPSSSSFIAPSYTLLDLGANYQLNDSLKFSAGIYNAFDKDITQEEYGYLEDGRRYWL
CCCCCCCCCEECCCEEEEECCCCEEECCCCEECCCHHHHHHHCCCHHHCCCHHCCCEEEE
GMTYSF
EEEECC
>Mature Secondary Structure
MLLSRKKYLAQVITALCLLPAVPVTNALADTASDKEKMMERIVVTASGFEQQIRDAPASI
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHEEECCCHHHHHHCCCCEE
SVITREDLDNRFYRDLTDAMLEVPGVVITGGADRQDISLRGMGSQYTLILVDGKRQSSRE
EEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCEEEEEEEECCCCCCHH
TRTNSDGPGVEGAWTPPLAAIDRIEIVRGPMSSLYGSDAIGGVINIITRKVPNEWQGEVR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCEE
LDTTLQEKSTSGNVYQSNFFVNGGLIKDLLGMQLYGQYTQREEDNIYGGYRGRDATNLTA
EEEEHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
RFALTPNENHDIMLEVGVSNQELDSSLGKTVTPLAPGEACGRRGCPQSSTTEYENSTISL
EEEECCCCCCEEEEEECCCCHHHHHHHCCEECCCCCCHHHCCCCCCCCCCCCCCCCEEEE
SHTGRWDFGTSDSYIKHEVFDNKTRKMKITNTDVQSSLITTLGQSHTATFGAAFNHQDLT
EECCCCCCCCCCCCEEHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCC
DETGNQVSDLTDISRRQWSVFSEDEWRIVDNFALTMGLRLDDDENFGHHVSPRVYGVWGL
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCEEEEEEEC
TDSTTLKGGVSTGFRAPSLRQTVPDWGQVSRGGNMYGNPDLQPETSVNYELGVYSDLTES
CCCCEECCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCEEECCHHHHHHH
ITASAGVFYNEFKDKITRVACPATQCTDGPNQFGSDPTTYVNIDDAVTQGIELSIDYRIR
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCEEEECHHHHHCCEEEEEEEEEE
SNLSFTGNYTYTDSEQKTGAYKGSPLNQLPKHLIQASFNYEPIDNLSTWLRVNYRGEESQ
CCEEEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
PTTGPSSSSFIAPSYTLLDLGANYQLNDSLKFSAGIYNAFDKDITQEEYGYLEDGRRYWL
CCCCCCCCCEECCCEEEEECCCCEEECCCCEECCCHHHHHHHCCCHHHCCCHHCCCEEEE
GMTYSF
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]