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The map label for this gene is argB

Identifier: 160877314

GI number: 160877314

Start: 4978144

End: 4978926

Strand: Reverse

Name: argB

Synonym: Sbal195_4212

Alternate gene names: 160877314

Gene position: 4978926-4978144 (Counterclockwise)

Preceding gene: 160877315

Following gene: 160877313

Centisome position: 93.11

GC content: 50.32

Gene sequence:

>783_bases
ATGTCTACAAACAACTCAGTATTAGTTCTTAAAGTTGGTGGCGCGCTGCTGCAGTGTGAAATGGGGATGGCGCGGTTAAT
GGATACGGCTGCGGCTATGTTAGCCAATGGTCAGCAAGTGTTAATGGTGCATGGCGGCGGCTGTTTAGTGGATGAACAGT
TAGCGGCAAACGGCATGGAAACCGTCAAGTTAGAAGGTTTACGGGTGACTCCTCCTGAGCAAATGCCGATTATTGCCGGC
GCACTTGCGGGCACTTCGAACAAGATCCTCCAAGGCGCAGCGACTAAGGCTGGCATTGTGAGTGTGGGCATGAGCCTCGC
CGATGGCAATACTGTATCGGCAAAGATTAAAGATGAACGTTTAGGCCTAGTGGGTGAAGTGACGCCAAAAGATGGCGCTT
ATCTTAAGTTTATCCTCGCCCAAGGTTGGATGCCGATTTGTAGCTCTATCGCCATGATGGACGATGGCCAAATGCTTAAC
GTCAATGCTGACCAAGCTGCGACGGCCTTAGCCAAATTAGTGGGCGGCAAGTTAGTGCTGCTGTCGGATGTGTCTGGTGT
GCTCGATGGTAAAGGCCAGCTCATTCACAGTTTAAATGGCAAGCAGATAGCAGACCTTGTTAAACAAGGTGTGATCGAAA
AGGGAATGAAGGTCAAAGTTGAAGCTGCGCTCGAAGTCGCACAGTGGATGGGGCAGGCGGTTCAAGTTGCCTCGTGGCGT
GATGCAAGCCAATTAATCGCATTAGCAAAAGGTGAAGCCGTAGGAACACAAATCCAACCATAA

Upstream 100 bases:

>100_bases
ATCGATAATTTGATGAAAGGTGCTGCCAGCCAAGCGCTGCAATGCATAAAGATTCATTTTAACCTTTAATTGTTCATCCT
TATTTAAGAGAGTCGTCAAG

Downstream 100 bases:

>100_bases
GTGGAGTAGGTTATGAAGCATTTACTATCGATAAAAGAGTTAACCCAGCAGCAGTTACTTGATCTGATTGCCTTGGCAAA
AACGATCAAAGCCAATCCGG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSTNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQQVLMVHGGGCLVDEQLAANGMETVKLEGLRVTPPEQMPIIAG
ALAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDERLGLVGEVTPKDGAYLKFILAQGWMPICSSIAMMDDGQMLN
VNADQAATALAKLVGGKLVLLSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWR
DASQLIALAKGEAVGTQIQP

Sequences:

>Translated_260_residues
MSTNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQQVLMVHGGGCLVDEQLAANGMETVKLEGLRVTPPEQMPIIAG
ALAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDERLGLVGEVTPKDGAYLKFILAQGWMPICSSIAMMDDGQMLN
VNADQAATALAKLVGGKLVLLSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWR
DASQLIALAKGEAVGTQIQP
>Mature_259_residues
STNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQQVLMVHGGGCLVDEQLAANGMETVKLEGLRVTPPEQMPIIAGA
LAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDERLGLVGEVTPKDGAYLKFILAQGWMPICSSIAMMDDGQMLNV
NADQAATALAKLVGGKLVLLSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWRD
ASQLIALAKGEAVGTQIQP

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=252, Percent_Identity=47.6190476190476, Blast_Score=203, Evalue=9e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=235, Percent_Identity=28.0851063829787, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_SHEB2 (B8EBG2)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359909.1
- ProteinModelPortal:   B8EBG2
- SMR:   B8EBG2
- GeneID:   7086229
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_4013
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- ProtClustDB:   PRK00942
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 26845; Mature: 26714

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: BINDING 68-68 BINDING 160-160

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQQVLMVHGGGCLVDEQLAANGME
CCCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECHHHHHCCCC
TVKLEGLRVTPPEQMPIIAGALAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDER
EEEECCEEECCCCCCCEEEEECCCCCCHHHHCCCCCCHHHHHCEEECCCCEEEEEEECCC
LGLVGEVTPKDGAYLKFILAQGWMPICSSIAMMDDGQMLNVNADQAATALAKLVGGKLVL
CCEEEECCCCCCCEEEEEECCCCHHHHHHEEECCCCEEEEECHHHHHHHHHHHHCCCEEE
LSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWR
EECCCHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHEEHHCCC
DASQLIALAKGEAVGTQIQP
CHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
STNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQQVLMVHGGGCLVDEQLAANGME
CCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECHHHHHCCCC
TVKLEGLRVTPPEQMPIIAGALAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDER
EEEECCEEECCCCCCCEEEEECCCCCCHHHHCCCCCCHHHHHCEEECCCCEEEEEEECCC
LGLVGEVTPKDGAYLKFILAQGWMPICSSIAMMDDGQMLNVNADQAATALAKLVGGKLVL
CCEEEECCCCCCCEEEEEECCCCHHHHHHEEECCCCEEEEECHHHHHHHHHHHHCCCEEE
LSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWR
EECCCHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHEEHHCCC
DASQLIALAKGEAVGTQIQP
CHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA