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The map label for this gene is phoP [H]

Identifier: 160876979

GI number: 160876979

Start: 4567013

End: 4567687

Strand: Direct

Name: phoP [H]

Synonym: Sbal195_3875

Alternate gene names: 160876979

Gene position: 4567013-4567687 (Clockwise)

Preceding gene: 160876978

Following gene: 160876980

Centisome position: 85.41

GC content: 46.67

Gene sequence:

>675_bases
ATGAAACTGTTACTCGTTGAAGATAACCCTATGCTAGTCACCGAGCTGGAGAAACAACTCAAACTCGCTGGCTATGTGAC
CGATATTACTGACAAAGCGCTTGAAGCCGATTATCTGCTCAAAGAAACCCAATACGATTGCGTGATCTTAGATATCGGCT
TGCCCGACGGCAACGGCCTCGAACTACTCGAAGGCTGGCGTAATCAAGGGATCAGCACTCCAGTCATCATGCTGACCGCC
CGCAGCCAATGGCATGAAAAAGTCGAAGGCTTTAATGCCGGCGCCGACGATTACTTAGGCAAACCTTTCCACGCACAAGA
ATTATTGGCGCGTATTCAAGCCCTTATCCACCGTGCCCATGGCCGTTTAAATACTTCTAGCAAGCAATTGAGCTATGGCG
GCGTGATCTTAGACGAAGCCGAGCAAACGGTGAAAGTGGCAGACCAATTGTTTGAACTGACGGCGATGGAATTCAGATTA
TTGAAAATCTTCCTGATGTCGCCTAAGAAGCTGTTATCTAAGACACAGCTCACCGATAAGCTGTATCAGTTTGACGATGA
AAAAGAGAGTAATGTGGTCGAAGTTTATGTGACCCACTTACGTAAAAAATTAGGTAAAACCGCTATCGAAACCCGTCGCG
GCCAAGGTTATATCTTCCACGGCATTATTGAATGA

Upstream 100 bases:

>100_bases
CAAATCAAAGTTCAGCGTGGCCAAATCGTCAATCTCAGTATTGATGCAACCAATGGCCAAGCCGATCACTCAATAGCATT
ACCGAGCGAATGTCGAAAAC

Downstream 100 bases:

>100_bases
TCTCAATCCGCACTAAGCTCAGTTTATGGTTAACGGGCTTACTGGTAATAGGCACAGTCATTGGGCTCATCTTGTTTGAG
TCCATGCTGCGTCAGGCGTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKLLLVEDNPMLVTELEKQLKLAGYVTDITDKALEADYLLKETQYDCVILDIGLPDGNGLELLEGWRNQGISTPVIMLTA
RSQWHEKVEGFNAGADDYLGKPFHAQELLARIQALIHRAHGRLNTSSKQLSYGGVILDEAEQTVKVADQLFELTAMEFRL
LKIFLMSPKKLLSKTQLTDKLYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGIIE

Sequences:

>Translated_224_residues
MKLLLVEDNPMLVTELEKQLKLAGYVTDITDKALEADYLLKETQYDCVILDIGLPDGNGLELLEGWRNQGISTPVIMLTA
RSQWHEKVEGFNAGADDYLGKPFHAQELLARIQALIHRAHGRLNTSSKQLSYGGVILDEAEQTVKVADQLFELTAMEFRL
LKIFLMSPKKLLSKTQLTDKLYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGIIE
>Mature_224_residues
MKLLLVEDNPMLVTELEKQLKLAGYVTDITDKALEADYLLKETQYDCVILDIGLPDGNGLELLEGWRNQGISTPVIMLTA
RSQWHEKVEGFNAGADDYLGKPFHAQELLARIQALIHRAHGRLNTSSKQLSYGGVILDEAEQTVKVADQLFELTAMEFRL
LKIFLMSPKKLLSKTQLTDKLYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGIIE

Specific function: Member of the two-component regulatory system phoQ/phoP which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=39.4618834080717, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=38.3561643835616, Blast_Score=155, Evalue=1e-39,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=36.0730593607306, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=33.9285714285714, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=34.070796460177, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=32.2869955156951, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=179, Percent_Identity=35.7541899441341, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786599, Length=186, Percent_Identity=32.258064516129, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.5154185022026, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787229, Length=222, Percent_Identity=27.9279279279279, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=31.3304721030043, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788394, Length=205, Percent_Identity=29.7560975609756, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=31.1965811965812, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788550, Length=158, Percent_Identity=28.4810126582279, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25421; Mature: 25421

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLVEDNPMLVTELEKQLKLAGYVTDITDKALEADYLLKETQYDCVILDIGLPDGNGL
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCH
ELLEGWRNQGISTPVIMLTARSQWHEKVEGFNAGADDYLGKPFHAQELLARIQALIHRAH
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHH
GRLNTSSKQLSYGGVILDEAEQTVKVADQLFELTAMEFRLLKIFLMSPKKLLSKTQLTDK
CCCCCCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGIIE
HHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MKLLLVEDNPMLVTELEKQLKLAGYVTDITDKALEADYLLKETQYDCVILDIGLPDGNGL
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCH
ELLEGWRNQGISTPVIMLTARSQWHEKVEGFNAGADDYLGKPFHAQELLARIQALIHRAH
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHH
GRLNTSSKQLSYGGVILDEAEQTVKVADQLFELTAMEFRLLKIFLMSPKKLLSKTQLTDK
CCCCCCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGIIE
HHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA