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The map label for this gene is fbp [H]

Identifier: 160876948

GI number: 160876948

Start: 4527698

End: 4528675

Strand: Direct

Name: fbp [H]

Synonym: Sbal195_3844

Alternate gene names: 160876948

Gene position: 4527698-4528675 (Clockwise)

Preceding gene: 160876946

Following gene: 160876949

Centisome position: 84.67

GC content: 48.47

Gene sequence:

>978_bases
ATGCAGACTCTGACCCAGCACCTGACCTCACAGGCAGTGAACGACTCCCTCTCCCACCTAATTTTAACCTTAGCCGACAC
CTCAAAAGCCATTAGCCATGCCGTTCGCCACGGTGCGCTTGCAGGCGTGTTAGGCGCGACTGAGCAAGAAAACGTCCAAG
GTGAAACCCAGAAAAAACTGGATATCATCACCAACGATATGCTCAAAGATGCATTAAAAGCTGACGGTACAGTGCGCGGT
TTAGCGTCGGAAGAAGAAGATCATGTGGTTGAAGTCAGGCAAAATGGTCAATATCTGGTGTGTTTCGATCCGCTAGATGG
CTCATCTAATATTGATATCAACTCGTTAGTCGGCACGATTTTCTCTATCCTGCCCGCCCCTGCTGGCGAGTTGACTGAAA
CCAGCTTTTTACAATCTGGCCGCGCGCAATTAGCCGCAGGTTATGTACTTTATGGTCCATCGACCATGCTGGCATTAACC
ACTGGCCAAGGCGTGCAACTGTTTACGTTGGATCCAGAAACCAATGAGTTTTTACTGACTAACGCCGCCATGAGCATTAG
CCCAGAGACCCAAGAGTTTGCCATTAACATGTCGAACCAACGTTTTTGGGAAGCGCCAATGCAAACCTATATTGCCGATT
TACTGCTCGGTAAAATTGGCCCACGCGAAAAATCATTCAACATGCGCTGGATTGCGGCCATGGTCGGCGACGTACACCGC
GTGCTATCACGTGGCGGTATTTTTACTTACCCAAGCGACAATAAAGATCCGAAAAAACCGTACAAACTGCGCTTGATGTA
CGAAGCCAATCCAATGGCTTTCTTAGTTGAGCAAGCTGGCGGTAAAGCCTCAACGGGTTATGAAACTATTTTAGACATTA
CCCCAACGCATATTCACCAGCGTGTTGCCGTCATCCTAGGCAGTGCTAACGAAGTCGACGCTTGCCTGAGCTATCACGGT
ATTGATTCTCATAAATAG

Upstream 100 bases:

>100_bases
AAAAGCATCAGCAACATCGCTGAAATTGTCGACTAACTGAGTTATCATTCGCGGCAAATAACGAAATTGACCTCATTGTT
GAACCTCTAAAGGACATAAC

Downstream 100 bases:

>100_bases
AGAGTGTGAAGAGCCAAATATAGAGTAAGCCGAATCGCTTACTTTCTGATTTTTTGAATAAAAAGCCACTTATCAAAGTG
GCTTTTTTGTTGTCGCGTAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MQTLTQHLTSQAVNDSLSHLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
LASEEEDHVVEVRQNGQYLVCFDPLDGSSNIDINSLVGTIFSILPAPAGELTETSFLQSGRAQLAAGYVLYGPSTMLALT
TGQGVQLFTLDPETNEFLLTNAAMSISPETQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
VLSRGGIFTYPSDNKDPKKPYKLRLMYEANPMAFLVEQAGGKASTGYETILDITPTHIHQRVAVILGSANEVDACLSYHG
IDSHK

Sequences:

>Translated_325_residues
MQTLTQHLTSQAVNDSLSHLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
LASEEEDHVVEVRQNGQYLVCFDPLDGSSNIDINSLVGTIFSILPAPAGELTETSFLQSGRAQLAAGYVLYGPSTMLALT
TGQGVQLFTLDPETNEFLLTNAAMSISPETQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
VLSRGGIFTYPSDNKDPKKPYKLRLMYEANPMAFLVEQAGGKASTGYETILDITPTHIHQRVAVILGSANEVDACLSYHG
IDSHK
>Mature_325_residues
MQTLTQHLTSQAVNDSLSHLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
LASEEEDHVVEVRQNGQYLVCFDPLDGSSNIDINSLVGTIFSILPAPAGELTETSFLQSGRAQLAAGYVLYGPSTMLALT
TGQGVQLFTLDPETNEFLLTNAAMSISPETQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
VLSRGGIFTYPSDNKDPKKPYKLRLMYEANPMAFLVEQAGGKASTGYETILDITPTHIHQRVAVILGSANEVDACLSYHG
IDSHK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=301, Percent_Identity=44.1860465116279, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI16579888, Length=301, Percent_Identity=44.1860465116279, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI22907028, Length=326, Percent_Identity=40.7975460122699, Blast_Score=237, Evalue=1e-62,
Organism=Escherichia coli, GI1790679, Length=313, Percent_Identity=45.3674121405751, Blast_Score=244, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17508131, Length=305, Percent_Identity=43.2786885245902, Blast_Score=241, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6323409, Length=297, Percent_Identity=42.0875420875421, Blast_Score=238, Evalue=1e-63,
Organism=Drosophila melanogaster, GI19921562, Length=320, Percent_Identity=41.25, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI45550998, Length=320, Percent_Identity=41.25, Blast_Score=216, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35365; Mature: 35365

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLTQHLTSQAVNDSLSHLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKL
CCHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DIITNDMLKDALKADGTVRGLASEEEDHVVEVRQNGQYLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHH
FSILPAPAGELTETSFLQSGRAQLAAGYVLYGPSTMLALTTGQGVQLFTLDPETNEFLLT
HHHHCCCCCCHHHHHHHHCCCHHHHCCEEEECCCEEEEEECCCCEEEEEECCCCCCEEEE
NAAMSISPETQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
ECEEECCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VLSRGGIFTYPSDNKDPKKPYKLRLMYEANPMAFLVEQAGGKASTGYETILDITPTHIHQ
HHHCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
RVAVILGSANEVDACLSYHGIDSHK
EEHHEECCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQTLTQHLTSQAVNDSLSHLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKL
CCHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DIITNDMLKDALKADGTVRGLASEEEDHVVEVRQNGQYLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHH
FSILPAPAGELTETSFLQSGRAQLAAGYVLYGPSTMLALTTGQGVQLFTLDPETNEFLLT
HHHHCCCCCCHHHHHHHHCCCHHHHCCEEEECCCEEEEEECCCCEEEEEECCCCCCEEEE
NAAMSISPETQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
ECEEECCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VLSRGGIFTYPSDNKDPKKPYKLRLMYEANPMAFLVEQAGGKASTGYETILDITPTHIHQ
HHHCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
RVAVILGSANEVDACLSYHGIDSHK
EEHHEECCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA