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The map label for this gene is panE [H]

Identifier: 160876830

GI number: 160876830

Start: 4392551

End: 4393489

Strand: Direct

Name: panE [H]

Synonym: Sbal195_3726

Alternate gene names: 160876830

Gene position: 4392551-4393489 (Clockwise)

Preceding gene: 160876829

Following gene: 160876831

Centisome position: 82.15

GC content: 49.84

Gene sequence:

>939_bases
ATGACTCATGCTGTGGATATTGCCATTTTAGGTGCAGGTGCCGTTGGACAACTGATCTGTCGCCAATTGACAGTAGCGGG
CATGAATATCGGTTTTATCGGCCGTAATGCCCTCGAAGCTAGCCAGCAGGTCCTGAGTTTCACCCCATTAGCGTCTGCCG
ATGACAAGCAACAGCAGATACACGCTATCCCGTATTCGGTGCCTATCTTAACTGCCGATACGCTCGACAATATCCGTCTG
GTGATTGTCTGCGTTAAAGCCTATCAAGTGCTTGATGCGCTTTCTCCCTTACTCAAGCAACTGCCTAATCAATGTCATAT
TTTGTTATTACACAATGGCATGGGACCTCATTTAGCACTGGCACCGCTCATTGATGCACAAGCTAATGGCAGAGGGCTAA
GCTTAGGGACAACGTCTCAAGGGGTGTTACGCCAAGCCCCTTGGCAGATTAAGCAAACCGGACAAGGGCTGACTCAGCTG
GGGCATTTCACAGGCGCTGAACTGACGGAGCATTATCGCAACGCTTTGCTGGCTGCCATTCCGAGCAGTGAATGGGTCGA
TGCGATTGTGCCTTGCCTGTGGCAAAAACTCGCAGTCAATGCCGCCATTAATCCGCTCACGGCGTTATATCAATGCCCCA
ATGGCAAACTGGCTGAGCCAGATTTTAGTGGCATGATAAATAGTATTCTCGATGAGTTAGTCATGGTTGCCGCACATGAT
GGTGTGTCGCTTGATAAATCATTTTTGCACGATAGGGTCTACCAAGTGATCCGTCTCACTGCGGGGAACTTCTCGTCGAT
GCACCAAGATATTGCGCATCAAAGGCGAACCGAGATTGACCAAATTAACGGCTATATCTGTGAGCGCGCACAAGCGCACG
GTTTAAGTGCGCCAGTCAATGCCGAGCTTTGGGCGCGAGTCAAACAGCTAGTAGTTTAA

Upstream 100 bases:

>100_bases
AATTGGGCCTATGGCAAATACTTTCGTGCGGCTCAGTTGCGGGAAGATTAGTTTGAACGCTTTAAATGGGCGCTGATACA
GAAATCTTAAGGCTGCGAAT

Downstream 100 bases:

>100_bases
CCGAGTACAACTAGCCTAGTACAACCAAAGTTAAAATATTGTTTAATCATGATAATCTGTAAATAACGATTTAATTTCCC
GCACTCATGCAGCGTATTAA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTHAVDIAILGAGAVGQLICRQLTVAGMNIGFIGRNALEASQQVLSFTPLASADDKQQQIHAIPYSVPILTADTLDNIRL
VIVCVKAYQVLDALSPLLKQLPNQCHILLLHNGMGPHLALAPLIDAQANGRGLSLGTTSQGVLRQAPWQIKQTGQGLTQL
GHFTGAELTEHYRNALLAAIPSSEWVDAIVPCLWQKLAVNAAINPLTALYQCPNGKLAEPDFSGMINSILDELVMVAAHD
GVSLDKSFLHDRVYQVIRLTAGNFSSMHQDIAHQRRTEIDQINGYICERAQAHGLSAPVNAELWARVKQLVV

Sequences:

>Translated_312_residues
MTHAVDIAILGAGAVGQLICRQLTVAGMNIGFIGRNALEASQQVLSFTPLASADDKQQQIHAIPYSVPILTADTLDNIRL
VIVCVKAYQVLDALSPLLKQLPNQCHILLLHNGMGPHLALAPLIDAQANGRGLSLGTTSQGVLRQAPWQIKQTGQGLTQL
GHFTGAELTEHYRNALLAAIPSSEWVDAIVPCLWQKLAVNAAINPLTALYQCPNGKLAEPDFSGMINSILDELVMVAAHD
GVSLDKSFLHDRVYQVIRLTAGNFSSMHQDIAHQRRTEIDQINGYICERAQAHGLSAPVNAELWARVKQLVV
>Mature_311_residues
THAVDIAILGAGAVGQLICRQLTVAGMNIGFIGRNALEASQQVLSFTPLASADDKQQQIHAIPYSVPILTADTLDNIRLV
IVCVKAYQVLDALSPLLKQLPNQCHILLLHNGMGPHLALAPLIDAQANGRGLSLGTTSQGVLRQAPWQIKQTGQGLTQLG
HFTGAELTEHYRNALLAAIPSSEWVDAIVPCLWQKLAVNAAINPLTALYQCPNGKLAEPDFSGMINSILDELVMVAAHDG
VSLDKSFLHDRVYQVIRLTAGNFSSMHQDIAHQRRTEIDQINGYICERAQAHGLSAPVNAELWARVKQLVV

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=306, Percent_Identity=34.9673202614379, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33742; Mature: 33611

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHAVDIAILGAGAVGQLICRQLTVAGMNIGFIGRNALEASQQVLSFTPLASADDKQQQI
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
HAIPYSVPILTADTLDNIRLVIVCVKAYQVLDALSPLLKQLPNQCHILLLHNGMGPHLAL
HCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHH
APLIDAQANGRGLSLGTTSQGVLRQAPWQIKQTGQGLTQLGHFTGAELTEHYRNALLAAI
HHHHCCCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
PSSEWVDAIVPCLWQKLAVNAAINPLTALYQCPNGKLAEPDFSGMINSILDELVMVAAHD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GVSLDKSFLHDRVYQVIRLTAGNFSSMHQDIAHQRRTEIDQINGYICERAQAHGLSAPVN
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AELWARVKQLVV
HHHHHHHHHHCC
>Mature Secondary Structure 
THAVDIAILGAGAVGQLICRQLTVAGMNIGFIGRNALEASQQVLSFTPLASADDKQQQI
CCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
HAIPYSVPILTADTLDNIRLVIVCVKAYQVLDALSPLLKQLPNQCHILLLHNGMGPHLAL
HCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHH
APLIDAQANGRGLSLGTTSQGVLRQAPWQIKQTGQGLTQLGHFTGAELTEHYRNALLAAI
HHHHCCCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
PSSEWVDAIVPCLWQKLAVNAAINPLTALYQCPNGKLAEPDFSGMINSILDELVMVAAHD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GVSLDKSFLHDRVYQVIRLTAGNFSSMHQDIAHQRRTEIDQINGYICERAQAHGLSAPVN
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AELWARVKQLVV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]