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The map label for this gene is epd [H]

Identifier: 160876764

GI number: 160876764

Start: 4315945

End: 4317018

Strand: Reverse

Name: epd [H]

Synonym: Sbal195_3658

Alternate gene names: 160876764

Gene position: 4317018-4315945 (Counterclockwise)

Preceding gene: 160876765

Following gene: 160876763

Centisome position: 80.73

GC content: 50.0

Gene sequence:

>1074_bases
ATGCGGCCTGCAATCTTTTGCAGGCCGTTTTTGTATTTAGAGGAAATTGAGACCTCAATGATCCGAGTCGCTATCAATGG
TTATGGCCGTATCGGCCGCTCTATTCTTCGTGCTTTGTACGAGTCTGGAAAACGGCAGCAAATGCAGATTGTCGCGATTA
ATGAATTAGCTAAACCTGAAGCCATTATTCATCTGACCCAGTACGACACCACCCACGGTCGGTTTGCGCACAAAGTGAAA
CTCGTCGATGATCACATGCTGATTGGCGACGATGCGATAAAAATTCTCCACGAGCCCGATCCCACAAAACTCCCTTGGCA
TGAGATGGACATAGACATTGTCTATGAGGCCACTGGTGTATTACTCGATCGTCAAAGCTGCGAAGCCCATATTCATGCTG
GCGCTAAACAAGTGCTGATAAGCCATCCATCCTCAGCCGATGTTGATGGCACGATTGTCTATGGGGTGAACCACGATTTA
CTCCGCGCCGAACACACAGTCGTTTCTAACGCTTCTTGTACGACTAACTGTATCGTACCTGTGATCGACGTGCTCGACCG
CCACTTCGGCGTTAAAAGCGGCGCCATTACCACTATCCATTCGGCAATGAACGATCAGCAAGTGATTGATGCTTATCATG
ATGATTTACGTCGTACCCGCGCCGCTGGCCAATCGATTATCCCTGTAGACACTAAGCTTGCCCGCGGTATTGAGCGGATT
TTGCCGCATATGAAAGATAAGTTTGAAGCGATTTCGGTGCGCGTGCCCACCATCAACGTGACCGCGATCGATTTGTCTGT
GACGCTTGAGAAAACCGTCGATATTGCCACTGTGAACCAGGTGCTGGAGTCGGCCGCCAATGGGCGATTTAACGGCATTT
TGGGTTATACTGATGAGCCCTTGGTTTCATGTGATTTCAACCATGATCCCCGCTCCAGTATTGTTGACGGTACCCAGACC
CGTGTCAGCGCCGGTCAGCTGGTGAAGTTACTGTTGTGGTGCGATAACGAGTGGGGTTTTGCCAACCGTATGTTAGATAC
GAGTTTGGCAATGATCGCGGCCAAGCGAGGCTGA

Upstream 100 bases:

>100_bases
CCGTTGAAAATGTGCTGAATGCTGCAAAATCATTGGGCTAATCGCCCAAGGGATTAGATTCAATACAAAAGGTTAAACTT
TTTAAGTGTTAATCTGTATA

Downstream 100 bases:

>100_bases
TAAAAAGTAGATTATTCACCGGTGGGTCACTCAGTTATATGCCAATTCGACGGGATGTCGAGCGCCTAGCGGCAGTAAAC
TGATACCGGCCATGTGTGAA

Product: erythrose 4-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRPAIFCRPFLYLEEIETSMIRVAINGYGRIGRSILRALYESGKRQQMQIVAINELAKPEAIIHLTQYDTTHGRFAHKVK
LVDDHMLIGDDAIKILHEPDPTKLPWHEMDIDIVYEATGVLLDRQSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNHDL
LRAEHTVVSNASCTTNCIVPVIDVLDRHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERI
LPHMKDKFEAISVRVPTINVTAIDLSVTLEKTVDIATVNQVLESAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQT
RVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKRG

Sequences:

>Translated_357_residues
MRPAIFCRPFLYLEEIETSMIRVAINGYGRIGRSILRALYESGKRQQMQIVAINELAKPEAIIHLTQYDTTHGRFAHKVK
LVDDHMLIGDDAIKILHEPDPTKLPWHEMDIDIVYEATGVLLDRQSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNHDL
LRAEHTVVSNASCTTNCIVPVIDVLDRHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERI
LPHMKDKFEAISVRVPTINVTAIDLSVTLEKTVDIATVNQVLESAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQT
RVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKRG
>Mature_357_residues
MRPAIFCRPFLYLEEIETSMIRVAINGYGRIGRSILRALYESGKRQQMQIVAINELAKPEAIIHLTQYDTTHGRFAHKVK
LVDDHMLIGDDAIKILHEPDPTKLPWHEMDIDIVYEATGVLLDRQSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNHDL
LRAEHTVVSNASCTTNCIVPVIDVLDRHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERI
LPHMKDKFEAISVRVPTINVTAIDLSVTLEKTVDIATVNQVLESAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQT
RVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKRG

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=38.7573964497041, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=36.6666666666667, Blast_Score=229, Evalue=2e-60,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=65.8610271903323, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=40.0611620795107, Blast_Score=263, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17534677, Length=336, Percent_Identity=39.2857142857143, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17534679, Length=336, Percent_Identity=38.9880952380952, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=341, Percent_Identity=38.41642228739, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17568413, Length=341, Percent_Identity=38.41642228739, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=38.6018237082067, Blast_Score=259, Evalue=6e-70,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=38.6018237082067, Blast_Score=256, Evalue=5e-69,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=38.2978723404255, Blast_Score=255, Evalue=8e-69,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=37.3860182370821, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=37.3860182370821, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI85725000, Length=329, Percent_Identity=37.3860182370821, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI22023983, Length=329, Percent_Identity=37.3860182370821, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=34.3373493975904, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 39571; Mature: 39571

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAIFCRPFLYLEEIETSMIRVAINGYGRIGRSILRALYESGKRQQMQIVAINELAKPE
CCCCEEECHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
AIIHLTQYDTTHGRFAHKVKLVDDHMLIGDDAIKILHEPDPTKLPWHEMDIDIVYEATGV
EEEEEEECCCCCCCEEEEEEEECCEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCE
LLDRQSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNHDLLRAEHTVVSNASCTTNCIVP
EEECCHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCHHHHHHHHEECCCCCCCCHHHH
VIDVLDRHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERI
HHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LPHMKDKFEAISVRVPTINVTAIDLSVTLEKTVDIATVNQVLESAANGRFNGILGYTDEP
HHHHHCCCEEEEEEECEEEEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
LVSCDFNHDPRSSIVDGTQTRVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKRG
EEEECCCCCCCHHHCCCCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MRPAIFCRPFLYLEEIETSMIRVAINGYGRIGRSILRALYESGKRQQMQIVAINELAKPE
CCCCEEECHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
AIIHLTQYDTTHGRFAHKVKLVDDHMLIGDDAIKILHEPDPTKLPWHEMDIDIVYEATGV
EEEEEEECCCCCCCEEEEEEEECCEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCE
LLDRQSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNHDLLRAEHTVVSNASCTTNCIVP
EEECCHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCHHHHHHHHEECCCCCCCCHHHH
VIDVLDRHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERI
HHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LPHMKDKFEAISVRVPTINVTAIDLSVTLEKTVDIATVNQVLESAANGRFNGILGYTDEP
HHHHHCCCEEEEEEECEEEEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
LVSCDFNHDPRSSIVDGTQTRVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKRG
EEEECCCCCCCHHHCCCCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA