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The map label for this gene is fba [H]

Identifier: 160876762

GI number: 160876762

Start: 4313313

End: 4314380

Strand: Reverse

Name: fba [H]

Synonym: Sbal195_3656

Alternate gene names: 160876762

Gene position: 4314380-4313313 (Counterclockwise)

Preceding gene: 160876763

Following gene: 160876761

Centisome position: 80.68

GC content: 47.85

Gene sequence:

>1068_bases
ATGGCGTTAATTTCCCTACGACAACTACTCGACCACGCGGCAGAACATGGATACGGTGTGCCTGCGTTCAACGTTAACAA
CTTAGAGCAGATGCGTGCCATCATGCAGGCCGCTGAAGCAACAGACAGCCCTGTTATTGTGCAAGCTTCTGCTGGTGCGC
GTAAATATGCTCGCCCACAGTTCTTAAAATATTTGATGGCTGCAGCCCTTGAGCAGTATCCAGATATTCCTGTGTGTATC
CACCAAGACCACGGTACCGATCCTGATATCTGTCAGCGTTCTATCCAATTAGGCATGTCATCAGTGATGATGGATGGCTC
TTTGATGGCTGACGGCAAAACCCCTGCATCGTATGACTACAACGTCGATGTCACTCGTCGCACAGTGGCATTTGCCCATG
CGTGTGGTGTGTCAGTTGAAGGCGAAATCGGCTGTTTAGGCAGTTTAGAAACTGGCCAAGCAGGCGAAGAAGACGGTATT
GGTGCAGTGGGTACATTAAGCATGGATCAAATGCTGACCACTCCTGATGAAGCGGCGCGTTTCGTTGCTGATACCCATGT
TGATGCACTTGCCATCGCTATCGGTACTAGCCACGGTGCTTACAAGTTCAGCCGTAAACCTACGGGTGATGTACTGCGAA
TCGACCGCATCAAAGAAATCCATGCGCGTATTCCTAATACTCACTTAGTGATGCACGGTTCATCTTCAGTGCCACAAGAA
TGGTTACAGATCATCAACCAATATGGTGGTCAGATCCCAGAAACCTACGGCGTGCCATTAGAAGAAATCGTTGAAGGTAT
CAAGCACGGTGTGCGTAAGGTGAATATCGATACTGACTTACGTTTAGCATCAACGGGTGCGGTACGTAAGTTCTTAGCGG
AACACCCAAGTGAATTTGACCCACGTAAATTCTTGAAAGCGTCAATGGAAGCCATGGCAGACATCTGTACTGTTCGCTAC
GAAGCTTTCGGTTGTGCTGGTCAAGCATCTAAGATTAAACCATTGTCTTTACAAGCAATGTATAAAGCGTATCAGTCTGG
CGCGTTAGATCCTAAGATCAACATGTAA

Upstream 100 bases:

>100_bases
ATCTATTTGAATACGGGTATAGAAATCCATCCAAACGATAGTGACCTCGGTGACCAAGCGTTGCAGAATGTGACAGTCAC
CCTATTATTGGAGTTAAAAA

Downstream 100 bases:

>100_bases
GCGTTATCGCTAGGACAAAAACCCGCTAATGCGGGTTTTTTTATGCTTAAAATAGATGCAATTTTCATTTTTTAATCGTC
AATGCTAATATTGCGCAGAT

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMAAALEQYPDIPVCI
HQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYDYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGQAGEEDGI
GAVGTLSMDQMLTTPDEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
WLQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAEHPSEFDPRKFLKASMEAMADICTVRY
EAFGCAGQASKIKPLSLQAMYKAYQSGALDPKINM

Sequences:

>Translated_355_residues
MALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMAAALEQYPDIPVCI
HQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYDYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGQAGEEDGI
GAVGTLSMDQMLTTPDEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
WLQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAEHPSEFDPRKFLKASMEAMADICTVRY
EAFGCAGQASKIKPLSLQAMYKAYQSGALDPKINM
>Mature_354_residues
ALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMAAALEQYPDIPVCIH
QDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYDYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGQAGEEDGIG
AVGTLSMDQMLTTPDEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQEW
LQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAEHPSEFDPRKFLKASMEAMADICTVRYE
AFGCAGQASKIKPLSLQAMYKAYQSGALDPKINM

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=330, Percent_Identity=33.030303030303, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=32.8267477203647, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1788072, Length=291, Percent_Identity=28.5223367697594, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38494; Mature: 38363

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQ
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCHH
FLKYLMAAALEQYPDIPVCIHQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYDY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
NVDVTRRTVAFAHACGVSVEGEIGCLGSLETGQAGEEDGIGAVGTLSMDQMLTTPDEAAR
CCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCEEEECCHHHHHCCHHHHHH
FVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
HHHHHCHHEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
WLQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAEHPSEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHHCCCCCC
PRKFLKASMEAMADICTVRYEAFGCAGQASKIKPLSLQAMYKAYQSGALDPKINM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCHH
FLKYLMAAALEQYPDIPVCIHQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYDY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
NVDVTRRTVAFAHACGVSVEGEIGCLGSLETGQAGEEDGIGAVGTLSMDQMLTTPDEAAR
CCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCEEEECCHHHHHCCHHHHHH
FVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
HHHHHCHHEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
WLQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAEHPSEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHHCCCCCC
PRKFLKASMEAMADICTVRYEAFGCAGQASKIKPLSLQAMYKAYQSGALDPKINM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]