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The map label for this gene is pepN [H]

Identifier: 160876708

GI number: 160876708

Start: 4237164

End: 4239920

Strand: Direct

Name: pepN [H]

Synonym: Sbal195_3602

Alternate gene names: 160876708

Gene position: 4237164-4239920 (Clockwise)

Preceding gene: 160876707

Following gene: 160876709

Centisome position: 79.24

GC content: 47.7

Gene sequence:

>2757_bases
ATGATACTGGCTCAAATCGGCGCTGACGCGAGGGATCATTTGCCACTCAGGCAACCCCAAACTCCCGATATTGAAAGCAA
ATATCCAAGCAGAAAACAAAACAAATTGTTGAAGGATTCAGTTGTGAACTTGTTTAAAGCCAGTTTTGTTGCCCTTGCCT
GCGGCGCATTGATGTCGTGTGCCACCCAAAGCACTCTTAATACGGGTCCACGTGACGCCAGTGCTTACATTAGCCAGTAT
CAGGCTGCGCTGCGCTCGCAGATCATTTCCGATGTTCGCTATGAATTGGATTTTCAGCTCACAGGGGAAGCCGAGTTTTC
CGCCACCTCCAAAGTGACCTTTCAATTAAGTGAAATACCAAAACAACTGAGCTTAGATTTAAACAAGGCACAGATAAAAC
GCTTTATCATCAACGGCACCGCTGTATATCCAAACTATAATGGCGCTTACATTAGCTTAAATACGCGTCTGCTGACCTCG
GGTGAAAACACGGTTGAAGTGCAGTTTACTCGCCCTCACAGCACTAATGGCGAAGGCCTGCACCGTTTTAAAGATCCGGT
CGATGGCAAGGTCTACCTCTATTCGCATTTTGAACCCGCCGCCGCGCAGCAAATGTTTGCCGTATTCGACCAACCGGATA
TCAAAGCCAACTATCAGATTACGGTCACAGCGCCCAAAGATTGGCAAGTGATTAGCACTATGCGTGAAAGCCAAATCACT
CCAGCAGGCGCATACAATCGTTGGACCTTCCCTGATACGCCGAAACTCAGTCCGTATAACTTTTCTATGCATGCGGGCCC
TTACCACATGTGGCAAGACAACTCGGGCCGCTATCCGATGCGCCTGTTCGCCCGTGAATCTGTGGCTAATCAAGTCACAC
CGCAGGATTGGTTTAACTATACCAAACAAGGGTTAACCTTCTTCGATAACTACTTTGGCATTCCATATCCCTTTAAGAAA
TATGATCAAATTCTGGTGCCTGACTTCCTCTATGGCGCCATGGAAAACGCCGGTGCTGTGACCTTTGCCGAAGATCATTT
CCTCTATAAAGCAGCCATGACGGCAGATCAAAAACAAAGCCTAGCCGGCGTGATCATGCATGAAATGGCGCATCAATGGT
TTGGCGATCTCGTGACCATGAAATGGTGGAATGGCCTGTGGCTCAATGAAAGCTTTGCCTCCTTTATGGGCACGCTTGCG
ACTCAGGAAGCAACCGAATTCACCAATGCTTGGCGCACTTTTTACGCTAAAGGCAAACAAAGAGCTTATGAGCAGGACAG
CTTAGTCACTACGCATCCAATTGAAGTGCCAGTGGCAACAACCCAAAACGCCTTCGACAATATCGATGCGATCACTTATC
AAAAAGGCGCATCGACACTGAAACAACTGCGCCACTTGCTGGGCGACATGGTGTTTCGCCGTGGAGTCAGCAATTATTTA
AAACAATATAGTTATCAAAATGCCGAGTTAGATGATTTTATCAATAGCCTAGGCAAAGCCGCTGGTCGTGATTTAAGCGC
ATGGACTCAAGAATGGCTCTACAGCGCGGGCGTTAACACCATCAAGGCGGAATATCGCTGTGAAGGTAACCGTATCAGCG
ACTTTAGCTTGATACAGCTCCCAGCAAGCGCTGAGCTGCCAACATTACGCGAACAAAAAGTCCAAGTGGCCCTCTTTACC
CAAGGCCGCTTCGATTTGCGTCATGACGTCACTGTGCCTGTGACTTACAAGGGTGAGCGTACCGAAGTCAAACAACTGAT
TGGTGAGCGCTGCCCAGACTTAGTCTACCCAAACTTTGATGATTGGGGCTTTGTGAAAGTCGAGCTCGATGACAAATCCT
TTAACACCGCAAAACAGCAGTTGAGTAATGTGTCAGATCCACTGCTGCGCTCTATGCTGTGGCAAAGTCTGTGGGACAGC
GTTCGTGAAGGTAAATTGAGCTTAGATCAATACCTAAGCACAGTGTTTGTTAACGCGCCTGCTGAGACGGACTACACCAT
TGTTGGTCAGATCATCGATAGCATGTTGCGCTCGAAGCAGTATCTCGCACAAATCGCACCTATTCAGCAAAACTACGCTG
AGAATGCAATCAAAGGCTTAAGCCAGATGAGCCTTAGAAAAGCGATGGAAAGCAAAGGCGATAATGACTTCCAACGTATT
TGGTTCGATGCGTATGTCAGTTTAGCCAGCGACAGGGATTCACTGCGCCATTTAGCGCAACTCGTTGACGGTGAAACAAA
AATTAAGGGGTTAACCTTAGATCAAGATTTACGCTGGGCGATCATCACCCAGCTCAATCGCTATGATTTCCCTAACGCGC
AGCAACGTTTAACCAAAGAAGCGGCTAAGGATAATTCGGACTCAGGCGAAAAAGCAGCGCTTGCGGCGCAAGTGATCCGC
CCAGAAGCGGCAGCCAAACGTCGCTGGTTAAGCAAGGTTCATCAAGACAGCCTGCCTTTCTCCAAGCAACGGATCATTAT
GGAAAATCTTTATCCTGCGGAGCAGAAACTATTGAGCGCGGCTACGGCGGAAGAACGTCTGGCGAGCTTGAGGGATATGG
ATAAAAAAGGCCCTGTGTTTATGCGTAACTACGCTCACAACTTGATTCCTACTGATTGTAACTACACTAGCATAGCGGCA
TTGGATAAAGTGCTTGATAGCCAAACTGGATTATCGAATCTCACTCGCCGCAATCTATTAGAAACCCGTCAAATGGAACA
GCGCTGTGTACTGATCAAAAATAAAATGACCCAATGA

Upstream 100 bases:

>100_bases
AGATCCCAAGAAGCCAGCTTAAACGCTGGCTTTTTTTTACATTTTTAACATTGGTTATCCAAGGTAAATAAGGTAGTGTA
CTCGGCCAAAATACACTGCA

Downstream 100 bases:

>100_bases
GATTAAGGCCATTTTAGAATTAACAAGGAGCTTCTAGGAGCTCCTTTTTATGTGCCGTAATAAATGAAGCCTAAGCACGA
AGCAGAACAACAAGACTCTC

Product: aminopeptidase N

Products: NA

Alternate protein names: Alanine aminopeptidase; Lysyl aminopeptidase; Lys-AP [H]

Number of amino acids: Translated: 918; Mature: 918

Protein sequence:

>918_residues
MILAQIGADARDHLPLRQPQTPDIESKYPSRKQNKLLKDSVVNLFKASFVALACGALMSCATQSTLNTGPRDASAYISQY
QAALRSQIISDVRYELDFQLTGEAEFSATSKVTFQLSEIPKQLSLDLNKAQIKRFIINGTAVYPNYNGAYISLNTRLLTS
GENTVEVQFTRPHSTNGEGLHRFKDPVDGKVYLYSHFEPAAAQQMFAVFDQPDIKANYQITVTAPKDWQVISTMRESQIT
PAGAYNRWTFPDTPKLSPYNFSMHAGPYHMWQDNSGRYPMRLFARESVANQVTPQDWFNYTKQGLTFFDNYFGIPYPFKK
YDQILVPDFLYGAMENAGAVTFAEDHFLYKAAMTADQKQSLAGVIMHEMAHQWFGDLVTMKWWNGLWLNESFASFMGTLA
TQEATEFTNAWRTFYAKGKQRAYEQDSLVTTHPIEVPVATTQNAFDNIDAITYQKGASTLKQLRHLLGDMVFRRGVSNYL
KQYSYQNAELDDFINSLGKAAGRDLSAWTQEWLYSAGVNTIKAEYRCEGNRISDFSLIQLPASAELPTLREQKVQVALFT
QGRFDLRHDVTVPVTYKGERTEVKQLIGERCPDLVYPNFDDWGFVKVELDDKSFNTAKQQLSNVSDPLLRSMLWQSLWDS
VREGKLSLDQYLSTVFVNAPAETDYTIVGQIIDSMLRSKQYLAQIAPIQQNYAENAIKGLSQMSLRKAMESKGDNDFQRI
WFDAYVSLASDRDSLRHLAQLVDGETKIKGLTLDQDLRWAIITQLNRYDFPNAQQRLTKEAAKDNSDSGEKAALAAQVIR
PEAAAKRRWLSKVHQDSLPFSKQRIIMENLYPAEQKLLSAATAEERLASLRDMDKKGPVFMRNYAHNLIPTDCNYTSIAA
LDKVLDSQTGLSNLTRRNLLETRQMEQRCVLIKNKMTQ

Sequences:

>Translated_918_residues
MILAQIGADARDHLPLRQPQTPDIESKYPSRKQNKLLKDSVVNLFKASFVALACGALMSCATQSTLNTGPRDASAYISQY
QAALRSQIISDVRYELDFQLTGEAEFSATSKVTFQLSEIPKQLSLDLNKAQIKRFIINGTAVYPNYNGAYISLNTRLLTS
GENTVEVQFTRPHSTNGEGLHRFKDPVDGKVYLYSHFEPAAAQQMFAVFDQPDIKANYQITVTAPKDWQVISTMRESQIT
PAGAYNRWTFPDTPKLSPYNFSMHAGPYHMWQDNSGRYPMRLFARESVANQVTPQDWFNYTKQGLTFFDNYFGIPYPFKK
YDQILVPDFLYGAMENAGAVTFAEDHFLYKAAMTADQKQSLAGVIMHEMAHQWFGDLVTMKWWNGLWLNESFASFMGTLA
TQEATEFTNAWRTFYAKGKQRAYEQDSLVTTHPIEVPVATTQNAFDNIDAITYQKGASTLKQLRHLLGDMVFRRGVSNYL
KQYSYQNAELDDFINSLGKAAGRDLSAWTQEWLYSAGVNTIKAEYRCEGNRISDFSLIQLPASAELPTLREQKVQVALFT
QGRFDLRHDVTVPVTYKGERTEVKQLIGERCPDLVYPNFDDWGFVKVELDDKSFNTAKQQLSNVSDPLLRSMLWQSLWDS
VREGKLSLDQYLSTVFVNAPAETDYTIVGQIIDSMLRSKQYLAQIAPIQQNYAENAIKGLSQMSLRKAMESKGDNDFQRI
WFDAYVSLASDRDSLRHLAQLVDGETKIKGLTLDQDLRWAIITQLNRYDFPNAQQRLTKEAAKDNSDSGEKAALAAQVIR
PEAAAKRRWLSKVHQDSLPFSKQRIIMENLYPAEQKLLSAATAEERLASLRDMDKKGPVFMRNYAHNLIPTDCNYTSIAA
LDKVLDSQTGLSNLTRRNLLETRQMEQRCVLIKNKMTQ
>Mature_918_residues
MILAQIGADARDHLPLRQPQTPDIESKYPSRKQNKLLKDSVVNLFKASFVALACGALMSCATQSTLNTGPRDASAYISQY
QAALRSQIISDVRYELDFQLTGEAEFSATSKVTFQLSEIPKQLSLDLNKAQIKRFIINGTAVYPNYNGAYISLNTRLLTS
GENTVEVQFTRPHSTNGEGLHRFKDPVDGKVYLYSHFEPAAAQQMFAVFDQPDIKANYQITVTAPKDWQVISTMRESQIT
PAGAYNRWTFPDTPKLSPYNFSMHAGPYHMWQDNSGRYPMRLFARESVANQVTPQDWFNYTKQGLTFFDNYFGIPYPFKK
YDQILVPDFLYGAMENAGAVTFAEDHFLYKAAMTADQKQSLAGVIMHEMAHQWFGDLVTMKWWNGLWLNESFASFMGTLA
TQEATEFTNAWRTFYAKGKQRAYEQDSLVTTHPIEVPVATTQNAFDNIDAITYQKGASTLKQLRHLLGDMVFRRGVSNYL
KQYSYQNAELDDFINSLGKAAGRDLSAWTQEWLYSAGVNTIKAEYRCEGNRISDFSLIQLPASAELPTLREQKVQVALFT
QGRFDLRHDVTVPVTYKGERTEVKQLIGERCPDLVYPNFDDWGFVKVELDDKSFNTAKQQLSNVSDPLLRSMLWQSLWDS
VREGKLSLDQYLSTVFVNAPAETDYTIVGQIIDSMLRSKQYLAQIAPIQQNYAENAIKGLSQMSLRKAMESKGDNDFQRI
WFDAYVSLASDRDSLRHLAQLVDGETKIKGLTLDQDLRWAIITQLNRYDFPNAQQRLTKEAAKDNSDSGEKAALAAQVIR
PEAAAKRRWLSKVHQDSLPFSKQRIIMENLYPAEQKLLSAATAEERLASLRDMDKKGPVFMRNYAHNLIPTDCNYTSIAA
LDKVLDSQTGLSNLTRRNLLETRQMEQRCVLIKNKMTQ

Specific function: Aminopeptidase with broad substrate specificity to several peptides. Shows strong preference for leucine but cleaves also next to Arg and lysine in peptide-bond-containing substrates [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=399, Percent_Identity=31.8295739348371, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI61742775, Length=368, Percent_Identity=32.3369565217391, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI61742777, Length=368, Percent_Identity=32.3369565217391, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI157266300, Length=307, Percent_Identity=35.8306188925081, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI132814467, Length=357, Percent_Identity=33.0532212885154, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI310123622, Length=346, Percent_Identity=32.0809248554913, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI310133497, Length=346, Percent_Identity=31.7919075144509, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI194306629, Length=321, Percent_Identity=33.3333333333333, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI11641261, Length=321, Percent_Identity=33.3333333333333, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI94818901, Length=319, Percent_Identity=32.2884012539185, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI94818891, Length=319, Percent_Identity=32.2884012539185, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI7019561, Length=315, Percent_Identity=30.1587301587302, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI194239713, Length=326, Percent_Identity=30.0613496932515, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI4505029, Length=464, Percent_Identity=26.7241379310345, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI40316915, Length=314, Percent_Identity=23.8853503184713, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1787163, Length=369, Percent_Identity=24.9322493224932, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71989076, Length=610, Percent_Identity=28.0327868852459, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI71989071, Length=610, Percent_Identity=28.0327868852459, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI115533278, Length=416, Percent_Identity=28.8461538461538, Blast_Score=187, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI115533276, Length=416, Percent_Identity=28.8461538461538, Blast_Score=186, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17565628, Length=361, Percent_Identity=29.3628808864266, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71990873, Length=351, Percent_Identity=32.4786324786325, Blast_Score=159, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI133903840, Length=309, Percent_Identity=31.3915857605178, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17569221, Length=360, Percent_Identity=28.0555555555556, Blast_Score=133, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17569225, Length=387, Percent_Identity=26.3565891472868, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI193206928, Length=354, Percent_Identity=26.8361581920904, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI193206926, Length=354, Percent_Identity=26.8361581920904, Blast_Score=112, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71984353, Length=482, Percent_Identity=21.9917012448133, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71984339, Length=486, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17544504, Length=307, Percent_Identity=26.0586319218241, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71981298, Length=386, Percent_Identity=22.279792746114, Blast_Score=73, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI9755335, Length=374, Percent_Identity=34.4919786096257, Blast_Score=218, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6321837, Length=414, Percent_Identity=32.6086956521739, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6322054, Length=410, Percent_Identity=20.7317073170732, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24651025, Length=425, Percent_Identity=32, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24651023, Length=425, Percent_Identity=32, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24651021, Length=425, Percent_Identity=32, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI21358341, Length=431, Percent_Identity=31.0904872389791, Blast_Score=207, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24655252, Length=346, Percent_Identity=35.2601156069364, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24655257, Length=346, Percent_Identity=35.2601156069364, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24655274, Length=346, Percent_Identity=35.2601156069364, Blast_Score=198, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24655260, Length=346, Percent_Identity=35.2601156069364, Blast_Score=198, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24655265, Length=346, Percent_Identity=35.2601156069364, Blast_Score=198, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24655268, Length=346, Percent_Identity=35.2601156069364, Blast_Score=198, Evalue=2e-50,
Organism=Drosophila melanogaster, GI221379089, Length=340, Percent_Identity=33.5294117647059, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24651016, Length=425, Percent_Identity=29.8823529411765, Blast_Score=179, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24646514, Length=348, Percent_Identity=31.6091954022989, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24646516, Length=338, Percent_Identity=31.6568047337278, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24646518, Length=338, Percent_Identity=31.6568047337278, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24646510, Length=363, Percent_Identity=30.5785123966942, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24646512, Length=363, Percent_Identity=30.5785123966942, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI45550850, Length=469, Percent_Identity=27.5053304904051, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24650973, Length=469, Percent_Identity=27.5053304904051, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI161078673, Length=458, Percent_Identity=27.292576419214, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28571901, Length=462, Percent_Identity=27.4891774891775, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24648786, Length=346, Percent_Identity=29.4797687861272, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28571792, Length=311, Percent_Identity=29.903536977492, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI221330574, Length=404, Percent_Identity=26.980198019802, Blast_Score=147, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24648790, Length=403, Percent_Identity=27.7915632754342, Blast_Score=134, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24648784, Length=316, Percent_Identity=25.9493670886076, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281362221, Length=286, Percent_Identity=26.2237762237762, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24584504, Length=448, Percent_Identity=24.1071428571429, Blast_Score=110, Evalue=6e-24,
Organism=Drosophila melanogaster, GI221458256, Length=303, Percent_Identity=25.7425742574257, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281362224, Length=303, Percent_Identity=25.7425742574257, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24641062, Length=318, Percent_Identity=22.9559748427673, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641060, Length=346, Percent_Identity=25.1445086705202, Blast_Score=85, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24585062, Length=315, Percent_Identity=26.3492063492064, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24585064, Length=315, Percent_Identity=26.3492063492064, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24585066, Length=315, Percent_Identity=26.3492063492064, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550350, Length=315, Percent_Identity=26.031746031746, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007874, Length=371, Percent_Identity=21.0242587601078, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012778
- InterPro:   IPR001930
- InterPro:   IPR014782 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 104367; Mature: 104367

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILAQIGADARDHLPLRQPQTPDIESKYPSRKQNKLLKDSVVNLFKASFVALACGALMSC
CEEECCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATQSTLNTGPRDASAYISQYQAALRSQIISDVRYELDFQLTGEAEFSATSKVTFQLSEIP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEEEHHHCC
KQLSLDLNKAQIKRFIINGTAVYPNYNGAYISLNTRLLTSGENTVEVQFTRPHSTNGEGL
HHHCCCCCHHHHHHHHCCCEEECCCCCCEEEEEEEEEEECCCCEEEEEEECCCCCCCCCH
HRFKDPVDGKVYLYSHFEPAAAQQMFAVFDQPDIKANYQITVTAPKDWQVISTMRESQIT
HHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCC
PAGAYNRWTFPDTPKLSPYNFSMHAGPYHMWQDNSGRYPMRLFARESVANQVTPQDWFNY
CCCCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHH
TKQGLTFFDNYFGIPYPFKKYDQILVPDFLYGAMENAGAVTFAEDHFLYKAAMTADQKQS
HHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHHCHHHHHH
LAGVIMHEMAHQWFGDLVTMKWWNGLWLNESFASFMGTLATQEATEFTNAWRTFYAKGKQ
HHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAYEQDSLVTTHPIEVPVATTQNAFDNIDAITYQKGASTLKQLRHLLGDMVFRRGVSNYL
HHHHCCCCEEECCCEECCCCCCHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQYSYQNAELDDFINSLGKAAGRDLSAWTQEWLYSAGVNTIKAEYRCEGNRISDFSLIQL
HHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEC
PASAELPTLREQKVQVALFTQGRFDLRHDVTVPVTYKGERTEVKQLIGERCPDLVYPNFD
CCCCCCCCHHHCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCC
DWGFVKVELDDKSFNTAKQQLSNVSDPLLRSMLWQSLWDSVREGKLSLDQYLSTVFVNAP
CCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECC
AETDYTIVGQIIDSMLRSKQYLAQIAPIQQNYAENAIKGLSQMSLRKAMESKGDNDFQRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
WFDAYVSLASDRDSLRHLAQLVDGETKIKGLTLDQDLRWAIITQLNRYDFPNAQQRLTKE
HHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHH
AAKDNSDSGEKAALAAQVIRPEAAAKRRWLSKVHQDSLPFSKQRIIMENLYPAEQKLLSA
HHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHH
ATAEERLASLRDMDKKGPVFMRNYAHNLIPTDCNYTSIAALDKVLDSQTGLSNLTRRNLL
HHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
ETRQMEQRCVLIKNKMTQ
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILAQIGADARDHLPLRQPQTPDIESKYPSRKQNKLLKDSVVNLFKASFVALACGALMSC
CEEECCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATQSTLNTGPRDASAYISQYQAALRSQIISDVRYELDFQLTGEAEFSATSKVTFQLSEIP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEEEHHHCC
KQLSLDLNKAQIKRFIINGTAVYPNYNGAYISLNTRLLTSGENTVEVQFTRPHSTNGEGL
HHHCCCCCHHHHHHHHCCCEEECCCCCCEEEEEEEEEEECCCCEEEEEEECCCCCCCCCH
HRFKDPVDGKVYLYSHFEPAAAQQMFAVFDQPDIKANYQITVTAPKDWQVISTMRESQIT
HHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCC
PAGAYNRWTFPDTPKLSPYNFSMHAGPYHMWQDNSGRYPMRLFARESVANQVTPQDWFNY
CCCCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHH
TKQGLTFFDNYFGIPYPFKKYDQILVPDFLYGAMENAGAVTFAEDHFLYKAAMTADQKQS
HHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHHCHHHHHH
LAGVIMHEMAHQWFGDLVTMKWWNGLWLNESFASFMGTLATQEATEFTNAWRTFYAKGKQ
HHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAYEQDSLVTTHPIEVPVATTQNAFDNIDAITYQKGASTLKQLRHLLGDMVFRRGVSNYL
HHHHCCCCEEECCCEECCCCCCHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQYSYQNAELDDFINSLGKAAGRDLSAWTQEWLYSAGVNTIKAEYRCEGNRISDFSLIQL
HHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEC
PASAELPTLREQKVQVALFTQGRFDLRHDVTVPVTYKGERTEVKQLIGERCPDLVYPNFD
CCCCCCCCHHHCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCC
DWGFVKVELDDKSFNTAKQQLSNVSDPLLRSMLWQSLWDSVREGKLSLDQYLSTVFVNAP
CCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECC
AETDYTIVGQIIDSMLRSKQYLAQIAPIQQNYAENAIKGLSQMSLRKAMESKGDNDFQRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
WFDAYVSLASDRDSLRHLAQLVDGETKIKGLTLDQDLRWAIITQLNRYDFPNAQQRLTKE
HHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHH
AAKDNSDSGEKAALAAQVIRPEAAAKRRWLSKVHQDSLPFSKQRIIMENLYPAEQKLLSA
HHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHH
ATAEERLASLRDMDKKGPVFMRNYAHNLIPTDCNYTSIAALDKVLDSQTGLSNLTRRNLL
HHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
ETRQMEQRCVLIKNKMTQ
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7909302; 7765336 [H]