Click here to switch to the map view.

The map label for this gene is rlmG [H]

Identifier: 160876675

GI number: 160876675

Start: 4193954

End: 4195090

Strand: Direct

Name: rlmG [H]

Synonym: Sbal195_3569

Alternate gene names: 160876675

Gene position: 4193954-4195090 (Clockwise)

Preceding gene: 160876657

Following gene: 160876676

Centisome position: 78.43

GC content: 48.02

Gene sequence:

>1137_bases
ATGACAACACAATTTTCAGTAGCGGGTGTTGAACTCGAACTTTTACGGTATCCAGCTCAGCAAGAATCTAATCTTCAAGC
TTGGGATGCCGCCGATGAACACTTACTCAAAAGCCTTATTGAGTCAGAGCAAGCCGCCGTGCCAACCGCCATTATCAACG
ACAGTTTCGGCGCCTTAAGCTGTGGTGTATCGAAACTGAATCCAAGTTGGCCACTGTGTGTTGAAACCGATGCCAGAACC
AGCTTTTTAGGCACAGAGCAAAACCATGGCCGCAATCAGTTGCCGCTGGATAACCTGCAATGGTTTACCAGCCGCGATAC
CTTGCCAGAAAACTTAGCCTTAGTATTGATGAAGTTGCCTAAGAACTTAAGCTACTTTGCCCACCAGCTAACACGCTTAT
CGCAAGTGTTACCCGCTGGCACTCGTGTATTAGTGGCAGCCAAAGCCAAATCGATAAATGGCGCCTTGCTCGATATCTTT
GCTAAGCATTTAGGCCCAGCAAGCGCTAGTTTAGCGTGGAAAAACACCCGAGTGATTACCTGTGTCAGCGATGGTAAACC
CAGACCATTAGCCAAAGAAGTGACTTGGACCGTACCAGAATATCAACTTGAGATCAGCAACTTAAGTAATGTGTTTGCCG
CCAACAAACTCGATATTGGCGCACGTATCATGCTCGAAAATCTGCCGAAAGGGGATTTCAAGTCGATTGTCGATCTCGGT
TGTGGCAATGGCGTGCTGGGATTGCGAACCGCTCAGTTATTCCCAGAAGCTGATATCCACTTTATCGACGATTCTGAAAT
GGCGGTCGCATCAGCCAAGGCAAACTGGGCACGTAATCAATTGCCTGCAGATAAAGGCCACTTCTATTGGGACGACTGCA
TGACGCATCTGCCAGAAGAAGTGCAACCGGATCTGGTGCTATGTAATCCGCCCTTCCATCAAGGCGAAGCCATTACCGAT
CATATCGCGTGGCAGATGTTTTTAGATGCTCGCCGCCGCTTAAAAGACGGAGGTATTTTACATATCGTCGGCAACCGCCA
TCTGGCTTACCATGTGAAATTGCAGCGCTTATTTAAAAACTGCACCACAGTCGCCTCCAACGGTAAATTTGTGATCCTGC
AGGCGCAAAAGAAATAA

Upstream 100 bases:

>100_bases
CCATGGCAGGGCTAACATTCGCTCTTGATGCTGAGCCGTCGCACTGCGCCATGAAATCTGCGATAATCTGCGCCTTAAAT
TTATTGGCGCAGTGTGGCAC

Downstream 100 bases:

>100_bases
CCCTGCCGCAATTAGCACTTTAATCAGAGCCAGCAATGTCTGGCTCTTTGTTGAACTAAACCCGCTAAAATATTGTTCTA
CACCACTATCAGCATTTTCC

Product: rRNA (guanine-N(2)-)-methyltransferase

Products: NA

Alternate protein names: 23S rRNA m2G1835 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmG [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTTQFSVAGVELELLRYPAQQESNLQAWDAADEHLLKSLIESEQAAVPTAIINDSFGALSCGVSKLNPSWPLCVETDART
SFLGTEQNHGRNQLPLDNLQWFTSRDTLPENLALVLMKLPKNLSYFAHQLTRLSQVLPAGTRVLVAAKAKSINGALLDIF
AKHLGPASASLAWKNTRVITCVSDGKPRPLAKEVTWTVPEYQLEISNLSNVFAANKLDIGARIMLENLPKGDFKSIVDLG
CGNGVLGLRTAQLFPEADIHFIDDSEMAVASAKANWARNQLPADKGHFYWDDCMTHLPEEVQPDLVLCNPPFHQGEAITD
HIAWQMFLDARRRLKDGGILHIVGNRHLAYHVKLQRLFKNCTTVASNGKFVILQAQKK

Sequences:

>Translated_378_residues
MTTQFSVAGVELELLRYPAQQESNLQAWDAADEHLLKSLIESEQAAVPTAIINDSFGALSCGVSKLNPSWPLCVETDART
SFLGTEQNHGRNQLPLDNLQWFTSRDTLPENLALVLMKLPKNLSYFAHQLTRLSQVLPAGTRVLVAAKAKSINGALLDIF
AKHLGPASASLAWKNTRVITCVSDGKPRPLAKEVTWTVPEYQLEISNLSNVFAANKLDIGARIMLENLPKGDFKSIVDLG
CGNGVLGLRTAQLFPEADIHFIDDSEMAVASAKANWARNQLPADKGHFYWDDCMTHLPEEVQPDLVLCNPPFHQGEAITD
HIAWQMFLDARRRLKDGGILHIVGNRHLAYHVKLQRLFKNCTTVASNGKFVILQAQKK
>Mature_377_residues
TTQFSVAGVELELLRYPAQQESNLQAWDAADEHLLKSLIESEQAAVPTAIINDSFGALSCGVSKLNPSWPLCVETDARTS
FLGTEQNHGRNQLPLDNLQWFTSRDTLPENLALVLMKLPKNLSYFAHQLTRLSQVLPAGTRVLVAAKAKSINGALLDIFA
KHLGPASASLAWKNTRVITCVSDGKPRPLAKEVTWTVPEYQLEISNLSNVFAANKLDIGARIMLENLPKGDFKSIVDLGC
GNGVLGLRTAQLFPEADIHFIDDSEMAVASAKANWARNQLPADKGHFYWDDCMTHLPEEVQPDLVLCNPPFHQGEAITDH
IAWQMFLDARRRLKDGGILHIVGNRHLAYHVKLQRLFKNCTTVASNGKFVILQAQKK

Specific function: Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA [H]

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmG family [H]

Homologues:

Organism=Escherichia coli, GI87082206, Length=369, Percent_Identity=41.7344173441734, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI1790830, Length=256, Percent_Identity=26.171875, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR017237
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.174 [H]

Molecular weight: Translated: 41849; Mature: 41718

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQFSVAGVELELLRYPAQQESNLQAWDAADEHLLKSLIESEQAAVPTAIINDSFGALS
CCCEEEECCEEEEEECCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHH
CGVSKLNPSWPLCVETDARTSFLGTEQNHGRNQLPLDNLQWFTSRDTLPENLALVLMKLP
CCHHHCCCCCCEEEECCCCCEECCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHC
KNLSYFAHQLTRLSQVLPAGTRVLVAAKAKSINGALLDIFAKHLGPASASLAWKNTRVIT
CHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCEEEE
CVSDGKPRPLAKEVTWTVPEYQLEISNLSNVFAANKLDIGARIMLENLPKGDFKSIVDLG
EECCCCCCCCCCCEEECCCCEEEEHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCC
CGNGVLGLRTAQLFPEADIHFIDDSEMAVASAKANWARNQLPADKGHFYWDDCMTHLPEE
CCCCEEEEEHHHHCCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCCCEEHHHHHHHCCHH
VQPDLVLCNPPFHQGEAITDHIAWQMFLDARRRLKDGGILHIVGNRHLAYHVKLQRLFKN
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEHHHHHHHHH
CTTVASNGKFVILQAQKK
HHEEECCCCEEEEEECCC
>Mature Secondary Structure 
TTQFSVAGVELELLRYPAQQESNLQAWDAADEHLLKSLIESEQAAVPTAIINDSFGALS
CCEEEECCEEEEEECCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHH
CGVSKLNPSWPLCVETDARTSFLGTEQNHGRNQLPLDNLQWFTSRDTLPENLALVLMKLP
CCHHHCCCCCCEEEECCCCCEECCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHC
KNLSYFAHQLTRLSQVLPAGTRVLVAAKAKSINGALLDIFAKHLGPASASLAWKNTRVIT
CHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCEEEE
CVSDGKPRPLAKEVTWTVPEYQLEISNLSNVFAANKLDIGARIMLENLPKGDFKSIVDLG
EECCCCCCCCCCCEEECCCCEEEEHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCC
CGNGVLGLRTAQLFPEADIHFIDDSEMAVASAKANWARNQLPADKGHFYWDDCMTHLPEE
CCCCEEEEEHHHHCCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCCCEEHHHHHHHCCHH
VQPDLVLCNPPFHQGEAITDHIAWQMFLDARRRLKDGGILHIVGNRHLAYHVKLQRLFKN
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEHHHHHHHHH
CTTVASNGKFVILQAQKK
HHEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA