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The map label for this gene is lmrA [H]

Identifier: 160876338

GI number: 160876338

Start: 3800213

End: 3800827

Strand: Reverse

Name: lmrA [H]

Synonym: Sbal195_3232

Alternate gene names: 160876338

Gene position: 3800827-3800213 (Counterclockwise)

Preceding gene: 160876340

Following gene: 160876333

Centisome position: 71.08

GC content: 48.78

Gene sequence:

>615_bases
ATGCAGGGCACAGACATTCAGACGGGGATGCCACCGGATAAACGGCAACAATTGGTCACGACCGCCTTTAAACTGTTTTA
TTTTCAAAGTGTTCATGGAGTGGGGATTAATCAGATCCTGCAGGAATCGGCGATTGCCAAGAAAACCTTGTACCACCATT
TTGCCAGTAAAGATGAGTTAGTCGAAGCTGTGGTTCGCTATCGCGACGAGGTTTTTTATCAATGGCTTAGCGAGCGAGTG
AACGCATTGCCAGTGGGACGGGAGGGCATTTGTGGGTTATTTAGAGCGCTCGATGATTGGTTTAATCAAAGGGTTCCGCA
GTTGTGTGAGTTTCGCGGCTGTTTTTTTATCAACGTCAGCGCCGAATTTACTGAACCGAGCCATCCTGTACACCAACTCT
GCGCCCTGCATAAACAGCGAGTGGCGAGTTTAATTGAGCAGCAAGTCTCTGCATTGGGCTTGCCTAAAGCTAAGACCCAA
TACCTAGTTACTGCGATAGGTTTACTCAAAGAGGGCGCGATAGTGTCGGCACAACTAAAGGGTGACACTCAGTCAGCACT
ATTGGCGTTATCTGTGGTTGAGCAGCTGATCGATGCCGCGACTCATGCTGCTTAG

Upstream 100 bases:

>100_bases
CTCATGGGTAGACTGACTTGTCTACTTGTGAGAGGATATGACTGACATTTGCTAGCTAATGTTTGCTAACGAATGTTTAC
CAAAGATGAGGAATGAGTTG

Downstream 100 bases:

>100_bases
TTCACCACCCTTATCAAATGCTTTGCATAAAAGCGCTGACACAAAAGCCCTTACATAGGAGCCTTTACATAAGAGCATTA
GATAAACATATCTACGGCGC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MQGTDIQTGMPPDKRQQLVTTAFKLFYFQSVHGVGINQILQESAIAKKTLYHHFASKDELVEAVVRYRDEVFYQWLSERV
NALPVGREGICGLFRALDDWFNQRVPQLCEFRGCFFINVSAEFTEPSHPVHQLCALHKQRVASLIEQQVSALGLPKAKTQ
YLVTAIGLLKEGAIVSAQLKGDTQSALLALSVVEQLIDAATHAA

Sequences:

>Translated_204_residues
MQGTDIQTGMPPDKRQQLVTTAFKLFYFQSVHGVGINQILQESAIAKKTLYHHFASKDELVEAVVRYRDEVFYQWLSERV
NALPVGREGICGLFRALDDWFNQRVPQLCEFRGCFFINVSAEFTEPSHPVHQLCALHKQRVASLIEQQVSALGLPKAKTQ
YLVTAIGLLKEGAIVSAQLKGDTQSALLALSVVEQLIDAATHAA
>Mature_204_residues
MQGTDIQTGMPPDKRQQLVTTAFKLFYFQSVHGVGINQILQESAIAKKTLYHHFASKDELVEAVVRYRDEVFYQWLSERV
NALPVGREGICGLFRALDDWFNQRVPQLCEFRGCFFINVSAEFTEPSHPVHQLCALHKQRVASLIEQQVSALGLPKAKTQ
YLVTAIGLLKEGAIVSAQLKGDTQSALLALSVVEQLIDAATHAA

Specific function: Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22725; Mature: 22725

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGTDIQTGMPPDKRQQLVTTAFKLFYFQSVHGVGINQILQESAIAKKTLYHHFASKDEL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
VEAVVRYRDEVFYQWLSERVNALPVGREGICGLFRALDDWFNQRVPQLCEFRGCFFINVS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
AEFTEPSHPVHQLCALHKQRVASLIEQQVSALGLPKAKTQYLVTAIGLLKEGAIVSAQLK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEC
GDTQSALLALSVVEQLIDAATHAA
CCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQGTDIQTGMPPDKRQQLVTTAFKLFYFQSVHGVGINQILQESAIAKKTLYHHFASKDEL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
VEAVVRYRDEVFYQWLSERVNALPVGREGICGLFRALDDWFNQRVPQLCEFRGCFFINVS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
AEFTEPSHPVHQLCALHKQRVASLIEQQVSALGLPKAKTQYLVTAIGLLKEGAIVSAQLK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEC
GDTQSALLALSVVEQLIDAATHAA
CCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]