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The map label for this gene is xseA [H]

Identifier: 160876249

GI number: 160876249

Start: 3716280

End: 3717626

Strand: Direct

Name: xseA [H]

Synonym: Sbal195_3143

Alternate gene names: 160876249

Gene position: 3716280-3717626 (Clockwise)

Preceding gene: 160876245

Following gene: 160876258

Centisome position: 69.5

GC content: 49.52

Gene sequence:

>1347_bases
ATGCAAGGCGCCAAAAACAATATTTATACTGTCTCGCGACTCAATGGTGAAGTCAGACAAATTCTCGAGGGACAACTGGG
TAAAATTTGGCTAAATGGTGAAATATCCAACTTTTCCTCCCCCAGCTCAGGTCATTGGTATCTCACCTTAAAAGACCACT
CTTCCCAGATCCGTTGTGCCATGTTTAAAGGCCGTAACCAAACGGTCAGCTTTAAGCCCATCAATGGTCAGCAAGTGTTA
GTCAAAGGCGCGATCAGCGTGTATGAACCCAGAGGCGACTATCAATTATTGATTGAGTCCATGCTGCCAGCAGGGGATGG
ACTACTCGCCCAGCAATTCGATGCACTCAAAATGAAGCTCGCCGCCGAAGGATTATTCGCCGCCGACACCAAAAGACCAT
TGCCGAAAAATATCCAACGCATTGGCGTTATCACTTCACCAACCGGCGCAGCGATTCGCGATGTTCTACACGTACTAGCA
AGGCGCGACCCTTCAATTGAAGTCATTATCTATCCGACCCAAGTTCAAGGCGAAACTGCAGCACAGAGTATTTGTCAGGC
AATCAATATCGCCAACCAGCGTTTAGAGGTCGACGTATTACTGCTTACCCGTGGCGGCGGTTCGCTTGAGGATTTGTGGT
GTTTTAACAGCGAAGCCCTCGCCCACACAATTTATAACAGCGCCCTGCCCGTAGTCAGCGCCGTCGGCCATGAAGTCGAC
ACCACCATCAGTGATTACGTTGCTGATATTCGCGCCCCAACACCGTCTGCAGGTGCAGAGTTGTTATCCCAAGATAGCGA
CAATAAGGCGCAAAAACTCGCAACAGCTTTATCGCGCCTGCAACAAAGTGCGAAACATTATCAACTTAAGCAAGAAAGAC
GACTCAGTTTGCTTGAGCACAGACTGCAACGCCAAGATCCTAAACGGACCTTGCAACAGTTCGAGCAAAGATTCGATGAG
ATGCAATTAAGACTGGAGTCGGCGCTGTCGAATCGCTTGCACATACTCAGCCGCCGTCAGCAGTTGCTCGCAAGTCGCCT
TGAACAGCAATCTCCCAAGCATAAGCTCGCCATTGAGGGTAACCGCCTAAGTTATCTTGCGAGTCGCTTACAGGATGCAT
TACAGGACAAACTGAGCCAAAGTGAGCAACGGATACAATACGCGGCCCATCAACTTGAAACCGTCAGCCCGCTTGCTACC
TTAAGCCGTGGTTACAGCATCACCACTGACATCCACAATCAAGTGGCCGACTCTGCCGATAAACTGACAATCGGTGATAG
CCTGCAAACCCGCTTCCGCCATGGACAAGTGATTTCAACCGTCACTCAGATAAAGCTGCTTGAATAA

Upstream 100 bases:

>100_bases
AGTAGGATTTAGAGGTGAAATATTGCGGCGGGATTATACCTTGCATATCGGCACTGGTAAATGGAAAATAGCAAATATCC
CCATTTAATTGAGTAATTCG

Downstream 100 bases:

>100_bases
ATCTACATGACGCTGAAATAGTCTAACCAAGGCTAGCAGAGTTTAAGTAAGGCTGAAACGGTCTTAAAACACAAAAGGAA
CCCTAAGGTTCCTTTTGTTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MQGAKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCAMFKGRNQTVSFKPINGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKLAAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGETAAQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEHRLQRQDPKRTLQQFEQRFDE
MQLRLESALSNRLHILSRRQQLLASRLEQQSPKHKLAIEGNRLSYLASRLQDALQDKLSQSEQRIQYAAHQLETVSPLAT
LSRGYSITTDIHNQVADSADKLTIGDSLQTRFRHGQVISTVTQIKLLE

Sequences:

>Translated_448_residues
MQGAKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCAMFKGRNQTVSFKPINGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKLAAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGETAAQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEHRLQRQDPKRTLQQFEQRFDE
MQLRLESALSNRLHILSRRQQLLASRLEQQSPKHKLAIEGNRLSYLASRLQDALQDKLSQSEQRIQYAAHQLETVSPLAT
LSRGYSITTDIHNQVADSADKLTIGDSLQTRFRHGQVISTVTQIKLLE
>Mature_448_residues
MQGAKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCAMFKGRNQTVSFKPINGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKLAAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGETAAQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEHRLQRQDPKRTLQQFEQRFDE
MQLRLESALSNRLHILSRRQQLLASRLEQQSPKHKLAIEGNRLSYLASRLQDALQDKLSQSEQRIQYAAHQLETVSPLAT
LSRGYSITTDIHNQVADSADKLTIGDSLQTRFRHGQVISTVTQIKLLE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=438, Percent_Identity=49.5433789954338, Blast_Score=435, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49911; Mature: 49911

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGAKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCA
CCCCCCCEEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEE
MFKGRNQTVSFKPINGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKL
EECCCCCEEEEECCCCCEEEEEECHHEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLARRDPSIEVIIYPTQVQGETA
HHCCCEECCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
AQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
HHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHCCHHH
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEH
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQRQDPKRTLQQFEQRFDEMQLRLESALSNRLHILSRRQQLLASRLEQQSPKHKLAIEG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NRLSYLASRLQDALQDKLSQSEQRIQYAAHQLETVSPLATLSRGYSITTDIHNQVADSAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCC
KLTIGDSLQTRFRHGQVISTVTQIKLLE
CEEECHHHHHHHHCCHHHHHHHHHEECC
>Mature Secondary Structure
MQGAKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCA
CCCCCCCEEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEE
MFKGRNQTVSFKPINGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKL
EECCCCCEEEEECCCCCEEEEEECHHEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLARRDPSIEVIIYPTQVQGETA
HHCCCEECCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
AQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
HHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHCCHHH
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEH
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQRQDPKRTLQQFEQRFDEMQLRLESALSNRLHILSRRQQLLASRLEQQSPKHKLAIEG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NRLSYLASRLQDALQDKLSQSEQRIQYAAHQLETVSPLATLSRGYSITTDIHNQVADSAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCC
KLTIGDSLQTRFRHGQVISTVTQIKLLE
CEEECHHHHHHHHCCHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA