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The map label for this gene is mpg1 [H]

Identifier: 160876232

GI number: 160876232

Start: 3690380

End: 3691432

Strand: Reverse

Name: mpg1 [H]

Synonym: Sbal195_3126

Alternate gene names: 160876232

Gene position: 3691432-3690380 (Counterclockwise)

Preceding gene: 160876235

Following gene: 160876231

Centisome position: 69.03

GC content: 39.79

Gene sequence:

>1053_bases
ATGAATAATGGTTGGAAAAAGTCAGTAATTAAGCCTAGCGACACAATATTGAGGGCTATTGAGATATTGAACAATGAAGT
ACTCAAAGTCGTATTGGTCGTTAATGATTCTGGCTGTTTGCGTGGCACGATAACAGATGGGGATATCAGACGAGGTATTT
TGCGAGGCGTCTCTTTACAGTCTTCTGTAGAGGAGATCATGTTTGTTAATCCCGTTACCGCAATCAATGGGACACCTAAA
CGTGAACTCGCTAAAATCATGGATCAAAAATCGATCACATCGATACCTATCCTTGATAATGGCAAAGTCATAGATGTTCA
AACGTTAAAATCAGTCTCAAAGAAAAATGTGTATGATAATCCAGTTTTTTTAATGGCAGGGGGATTTGGTACACGATTAA
GGCCGCTGACCGACCATGCCCCAAAGCCAATGTTGAGTGTTGGTGGTCGTCCTATACTAGAGACCATTTTGTTAAGTTTT
ATTCGGGTTGGGTTTAAAAATTTCTATATTTCGGTTTTCTACAAACCAGAGATTATTAAATGTTACTTTGGTGATGGAAG
CAAATGGGGCGTTAGCATTCAGTATGTTCAGGAAGATCAGCCACTAGGTACTGCTGGTGCTCTAAGTCTATTGCCTCGAG
ATATGCCGAGTTTACCCATGATTATGATGAATGGGGATATCCTCACCAATGTTGATTTTGAAAGATTAATCGAATTCCAT
AATGATAATGGCGCGACGGCAACTATGTGCGTGCGAGATTATGAATACCAAGTTCCTTATGGTGTCATTGTTGGCGATGG
TCATCATATTTTGTCGATGGAAGAGAAGCCTATTCAACGTTTCTTTGTGAACGCAGGCATTTATGTATTAACGCCAGAAT
TGATTCGAGAAGTACGGCAAGACATTAAAATCGATATGCCAACGTTATTACAAAATACGATTGATAAAATGGAACAAGTG
CTCATGTTTCCCATCCATGAGTATTGGTTGGATATCGGCCGTTTAGATGATTTTGACCGTGCTCAAGCCGATATTGCCAT
GCTAGAGATTTAA

Upstream 100 bases:

>100_bases
TATAGGTGGCGTAACTTTTGCTTGAAGTACAATGTTTTACTATGTTGTCAATAAAATAACTTATGCTAACAGTACTGTAG
TCGTTTGGCGGGAGATAGTC

Downstream 100 bases:

>100_bases
CAAATGAATAAACGCGTATTAGCCCTTATTCCCGCACGCGCGGGCAGTAAACGTATTGTAAACAAAAACATTAAGCCTTT
TGCTGGTAAGCCATTAATAG

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MNNGWKKSVIKPSDTILRAIEILNNEVLKVVLVVNDSGCLRGTITDGDIRRGILRGVSLQSSVEEIMFVNPVTAINGTPK
RELAKIMDQKSITSIPILDNGKVIDVQTLKSVSKKNVYDNPVFLMAGGFGTRLRPLTDHAPKPMLSVGGRPILETILLSF
IRVGFKNFYISVFYKPEIIKCYFGDGSKWGVSIQYVQEDQPLGTAGALSLLPRDMPSLPMIMMNGDILTNVDFERLIEFH
NDNGATATMCVRDYEYQVPYGVIVGDGHHILSMEEKPIQRFFVNAGIYVLTPELIREVRQDIKIDMPTLLQNTIDKMEQV
LMFPIHEYWLDIGRLDDFDRAQADIAMLEI

Sequences:

>Translated_350_residues
MNNGWKKSVIKPSDTILRAIEILNNEVLKVVLVVNDSGCLRGTITDGDIRRGILRGVSLQSSVEEIMFVNPVTAINGTPK
RELAKIMDQKSITSIPILDNGKVIDVQTLKSVSKKNVYDNPVFLMAGGFGTRLRPLTDHAPKPMLSVGGRPILETILLSF
IRVGFKNFYISVFYKPEIIKCYFGDGSKWGVSIQYVQEDQPLGTAGALSLLPRDMPSLPMIMMNGDILTNVDFERLIEFH
NDNGATATMCVRDYEYQVPYGVIVGDGHHILSMEEKPIQRFFVNAGIYVLTPELIREVRQDIKIDMPTLLQNTIDKMEQV
LMFPIHEYWLDIGRLDDFDRAQADIAMLEI
>Mature_350_residues
MNNGWKKSVIKPSDTILRAIEILNNEVLKVVLVVNDSGCLRGTITDGDIRRGILRGVSLQSSVEEIMFVNPVTAINGTPK
RELAKIMDQKSITSIPILDNGKVIDVQTLKSVSKKNVYDNPVFLMAGGFGTRLRPLTDHAPKPMLSVGGRPILETILLSF
IRVGFKNFYISVFYKPEIIKCYFGDGSKWGVSIQYVQEDQPLGTAGALSLLPRDMPSLPMIMMNGDILTNVDFERLIEFH
NDNGATATMCVRDYEYQVPYGVIVGDGHHILSMEEKPIQRFFVNAGIYVLTPELIREVRQDIKIDMPTLLQNTIDKMEQV
LMFPIHEYWLDIGRLDDFDRAQADIAMLEI

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=230, Percent_Identity=30.8695652173913, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI11761619, Length=230, Percent_Identity=30.8695652173913, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI133931050, Length=233, Percent_Identity=27.8969957081545, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320148, Length=231, Percent_Identity=32.034632034632, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355443, Length=228, Percent_Identity=31.140350877193, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24644084, Length=228, Percent_Identity=31.140350877193, Blast_Score=114, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 39379; Mature: 39379

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNGWKKSVIKPSDTILRAIEILNNEVLKVVLVVNDSGCLRGTITDGDIRRGILRGVSLQ
CCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCEEEECCCCHHHHHHHHCCCHH
SSVEEIMFVNPVTAINGTPKRELAKIMDQKSITSIPILDNGKVIDVQTLKSVSKKNVYDN
HHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCEEEHHHHHHHHHCCCCCC
PVFLMAGGFGTRLRPLTDHAPKPMLSVGGRPILETILLSFIRVGFKNFYISVFYKPEIIK
CEEEEECCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCEEEEEEEECCCEEE
CYFGDGSKWGVSIQYVQEDQPLGTAGALSLLPRDMPSLPMIMMNGDILTNVDFERLIEFH
EEECCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCEEEECCCEEECCCHHHHHHHC
NDNGATATMCVRDYEYQVPYGVIVGDGHHILSMEEKPIQRFFVNAGIYVLTPELIREVRQ
CCCCCEEEEEEECCEEECCEEEEEECCCEEEECCHHHHHHHHHHCCEEEECHHHHHHHHH
DIKIDMPTLLQNTIDKMEQVLMFPIHEYWLDIGRLDDFDRAQADIAMLEI
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEEC
>Mature Secondary Structure
MNNGWKKSVIKPSDTILRAIEILNNEVLKVVLVVNDSGCLRGTITDGDIRRGILRGVSLQ
CCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCEEEECCCCHHHHHHHHCCCHH
SSVEEIMFVNPVTAINGTPKRELAKIMDQKSITSIPILDNGKVIDVQTLKSVSKKNVYDN
HHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCEEEHHHHHHHHHCCCCCC
PVFLMAGGFGTRLRPLTDHAPKPMLSVGGRPILETILLSFIRVGFKNFYISVFYKPEIIK
CEEEEECCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCEEEEEEEECCCEEE
CYFGDGSKWGVSIQYVQEDQPLGTAGALSLLPRDMPSLPMIMMNGDILTNVDFERLIEFH
EEECCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCEEEECCCEEECCCHHHHHHHC
NDNGATATMCVRDYEYQVPYGVIVGDGHHILSMEEKPIQRFFVNAGIYVLTPELIREVRQ
CCCCCEEEEEEECCEEECCEEEEEECCCEEEECCHHHHHHHHHHCCEEEECHHHHHHHHH
DIKIDMPTLLQNTIDKMEQVLMFPIHEYWLDIGRLDDFDRAQADIAMLEI
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]