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The map label for this gene is neuA [H]

Identifier: 160876231

GI number: 160876231

Start: 3689681

End: 3690376

Strand: Reverse

Name: neuA [H]

Synonym: Sbal195_3125

Alternate gene names: 160876231

Gene position: 3690376-3689681 (Counterclockwise)

Preceding gene: 160876232

Following gene: 160876230

Centisome position: 69.01

GC content: 39.22

Gene sequence:

>696_bases
ATGAATAAACGCGTATTAGCCCTTATTCCCGCACGCGCGGGCAGTAAACGTATTGTAAACAAAAACATTAAGCCTTTTGC
TGGTAAGCCATTAATAGCTTGGACCATAGAAGCTGCTAAAGCTTGTGAGAATATCACGGATGTTGTTGTAAGCACCGATG
GTGAAGATATCGCTGCGATAGCAAGACAATATGGGGCCGAAACACCATTTATGCGTCCTGATAATTTGTCATCGGACACT
GCATCTTCAATTGATGTAGTTTTGCATGCTATCGACTTTTTGTCTGAGAGTGGGAGAGATTATGATCTATTACTCTTGTT
GCAGCCCACATCTCCATTAAGAAGTTCATCGGATATATCCAGTGCAATTGATTTTTTTATGCTTAGTAATGCGCAAGGGG
TGATTTCAGTCTGTGAGTGCGAACATAGTCCTTTGTGGGCTAATGTCTTGTCTGAATCTAAGTCACTCGATAGTTTTATT
GCATCTGAAATCAGTGAATTGCGCAGCCAGGATTTGCCTGCTTACTATCGATTTAATGGCGCTATCTATTTATTTGATGT
GCAACAGTTACAGCTAAGAAAGTCATTTTTCTATTCCCCAAACGTTTTTGCTCATGTGATGAGTAAAGAAGACTCCATTG
ATATTGATACCGAGATTGATTTTCAATTTGGTGAATTTTTGGTATCTAAAAAATAG

Upstream 100 bases:

>100_bases
AGTGCTCATGTTTCCCATCCATGAGTATTGGTTGGATATCGGCCGTTTAGATGATTTTGACCGTGCTCAAGCCGATATTG
CCATGCTAGAGATTTAACAA

Downstream 100 bases:

>100_bases
TTAACCCTCCGTATTTAAAGGATAATATAATGACCCCCTCTGAAGGAAAATTAGATTTCTCAACTAATGCTTTTGGTGAG
AGATATTTATATCCTGTCAA

Product: N-acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNKRVLALIPARAGSKRIVNKNIKPFAGKPLIAWTIEAAKACENITDVVVSTDGEDIAAIARQYGAETPFMRPDNLSSDT
ASSIDVVLHAIDFLSESGRDYDLLLLLQPTSPLRSSSDISSAIDFFMLSNAQGVISVCECEHSPLWANVLSESKSLDSFI
ASEISELRSQDLPAYYRFNGAIYLFDVQQLQLRKSFFYSPNVFAHVMSKEDSIDIDTEIDFQFGEFLVSKK

Sequences:

>Translated_231_residues
MNKRVLALIPARAGSKRIVNKNIKPFAGKPLIAWTIEAAKACENITDVVVSTDGEDIAAIARQYGAETPFMRPDNLSSDT
ASSIDVVLHAIDFLSESGRDYDLLLLLQPTSPLRSSSDISSAIDFFMLSNAQGVISVCECEHSPLWANVLSESKSLDSFI
ASEISELRSQDLPAYYRFNGAIYLFDVQQLQLRKSFFYSPNVFAHVMSKEDSIDIDTEIDFQFGEFLVSKK
>Mature_231_residues
MNKRVLALIPARAGSKRIVNKNIKPFAGKPLIAWTIEAAKACENITDVVVSTDGEDIAAIARQYGAETPFMRPDNLSSDT
ASSIDVVLHAIDFLSESGRDYDLLLLLQPTSPLRSSSDISSAIDFFMLSNAQGVISVCECEHSPLWANVLSESKSLDSFI
ASEISELRSQDLPAYYRFNGAIYLFDVQQLQLRKSFFYSPNVFAHVMSKEDSIDIDTEIDFQFGEFLVSKK

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=228, Percent_Identity=30.2631578947368, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 25630; Mature: 25630

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRVLALIPARAGSKRIVNKNIKPFAGKPLIAWTIEAAKACENITDVVVSTDGEDIAAI
CCCEEEEEEECCCCCCHHHCCCCCCCCCCCEEEEEEHHHHHHCHHHEEEEECCCHHHHHH
ARQYGAETPFMRPDNLSSDTASSIDVVLHAIDFLSESGRDYDLLLLLQPTSPLRSSSDIS
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHH
SAIDFFMLSNAQGVISVCECEHSPLWANVLSESKSLDSFIASEISELRSQDLPAYYRFNG
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
AIYLFDVQQLQLRKSFFYSPNVFAHVMSKEDSIDIDTEIDFQFGEFLVSKK
EEEEEEHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEECCHHHHHHCCCC
>Mature Secondary Structure
MNKRVLALIPARAGSKRIVNKNIKPFAGKPLIAWTIEAAKACENITDVVVSTDGEDIAAI
CCCEEEEEEECCCCCCHHHCCCCCCCCCCCEEEEEEHHHHHHCHHHEEEEECCCHHHHHH
ARQYGAETPFMRPDNLSSDTASSIDVVLHAIDFLSESGRDYDLLLLLQPTSPLRSSSDIS
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHH
SAIDFFMLSNAQGVISVCECEHSPLWANVLSESKSLDSFIASEISELRSQDLPAYYRFNG
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
AIYLFDVQQLQLRKSFFYSPNVFAHVMSKEDSIDIDTEIDFQFGEFLVSKK
EEEEEEHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEECCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]