BacMap

Definition	Shewanella baltica OS195 chromosome, complete genome.
Accession	NC_009997
Length	5,347,283

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The map label for this gene is fabG [C]

Identifier: 160876072

GI number: 160876072

Start: 3517548

End: 3518486

Strand: Reverse

Name: fabG [C]

Synonym: Sbal195_2962

Alternate gene names: 160876072

Gene position: 3518486-3517548 (Counterclockwise)

Preceding gene: 160876074

Following gene: 160876071

Centisome position: 65.8

GC content: 48.78

Gene sequence:

>939_bases
ATGCGTTTCGATAATAAGGTGGCGTTAGTCACTGGGGCGGGAGCAGGGCTAGGTCGAGCCTATGCCATCATGTTGGCTGA
GCGGGGCGCGAAGGTGGTGCTCGTTGATCAGCCGTTATCGTCATCCGAGTCTATTTCTACCTATGGTGCTCAAACAATGC
CGGCCAACTTAGCATTGATGCAAACCTACTGCAGCATTATTAAACTCGGCGGTGACTGTCTCTACTTTGTGCTTGATGTT
AGCCAGCGGGATGAAGTAAACCGCATGGTCGAAGAAGTGATCCTACGTTGGCATCGCATTGATATCTTGATTAATAACGC
GGGGATCTACGGTGCTTGTCCGTTCGAGCACATTAAGCTTGAGCAGTGGCAACGGCAATTGGATGTCGATCTCAATGGCA
GTTTTTATCTGACGCAAGCCGTTTGGCCCTATATGCAACAACAGGATTATGGTCGGATCATGATGACGACGGGAGCTTCG
GCCTTGTTTGGTGATTTGCATCAAGTCGGTTTCAGCGCGAGTAAGATGGCGCTGGTGGGCATGGTAAATTGCTTATCGAT
AGAAGGAGAAATTCATAATATTCGTGTCAATAGTTTATGCCCGCAGGCCGTCACAGCGATGACCGCCAAACATTTAGCGA
GTGCGATTCAGCCGTTATTTTCCTTTGAGTCATTAACCGCCACAACGGCTTTTTTGGTGAGTGAACAGGCGCCCAATGGT
CAACACTTACTCGCAGGTGCGGGCAGTATCAGCCATGGCATGTTTGTCGAGTTTCAGCCGATGTATTTTAATGAGGGGCT
TTTTACGCCAGATAATCTCGCGCAGCAGTGGCCCCAGCTATACCAATCCTTTCCTGTTACTTTGCACTCCAGTGGTGAGG
ATAAAGTCTTGTCTTGGTCTCAGTTAAGCGCGTTAGAACACCATATTCAAATTGACTGA

Upstream 100 bases:

>100_bases
CTGGAAATACCACAGGTGCTAGTCGCCTTATGCGGGTTGTTTTTGAGCATTCATTGGCGGCGTTTTGCCGCTACTGTTAT
GCCGATAAGGATATATTTGG

Downstream 100 bases:

>100_bases
TGAGTGACACTGTTACTCATAACTCAGCCCATGACCTCTGTTATTAAACCGCGTTAACGGGTCAAGTAAAACCCTTCACA
ATACGCAGATGACACCCGCA

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRFDNKVALVTGAGAGLGRAYAIMLAERGAKVVLVDQPLSSSESISTYGAQTMPANLALMQTYCSIIKLGGDCLYFVLDV
SQRDEVNRMVEEVILRWHRIDILINNAGIYGACPFEHIKLEQWQRQLDVDLNGSFYLTQAVWPYMQQQDYGRIMMTTGAS
ALFGDLHQVGFSASKMALVGMVNCLSIEGEIHNIRVNSLCPQAVTAMTAKHLASAIQPLFSFESLTATTAFLVSEQAPNG
QHLLAGAGSISHGMFVEFQPMYFNEGLFTPDNLAQQWPQLYQSFPVTLHSSGEDKVLSWSQLSALEHHIQID

Sequences:

>Translated_312_residues
MRFDNKVALVTGAGAGLGRAYAIMLAERGAKVVLVDQPLSSSESISTYGAQTMPANLALMQTYCSIIKLGGDCLYFVLDV
SQRDEVNRMVEEVILRWHRIDILINNAGIYGACPFEHIKLEQWQRQLDVDLNGSFYLTQAVWPYMQQQDYGRIMMTTGAS
ALFGDLHQVGFSASKMALVGMVNCLSIEGEIHNIRVNSLCPQAVTAMTAKHLASAIQPLFSFESLTATTAFLVSEQAPNG
QHLLAGAGSISHGMFVEFQPMYFNEGLFTPDNLAQQWPQLYQSFPVTLHSSGEDKVLSWSQLSALEHHIQID
>Mature_312_residues
MRFDNKVALVTGAGAGLGRAYAIMLAERGAKVVLVDQPLSSSESISTYGAQTMPANLALMQTYCSIIKLGGDCLYFVLDV
SQRDEVNRMVEEVILRWHRIDILINNAGIYGACPFEHIKLEQWQRQLDVDLNGSFYLTQAVWPYMQQQDYGRIMMTTGAS
ALFGDLHQVGFSASKMALVGMVNCLSIEGEIHNIRVNSLCPQAVTAMTAKHLASAIQPLFSFESLTATTAFLVSEQAPNG
QHLLAGAGSISHGMFVEFQPMYFNEGLFTPDNLAQQWPQLYQSFPVTLHSSGEDKVLSWSQLSALEHHIQID

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=224, Percent_Identity=38.3928571428571, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI4758504, Length=207, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI83715985, Length=187, Percent_Identity=31.5508021390374, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32483357, Length=266, Percent_Identity=26.6917293233083, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=30.8333333333333, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI210032110, Length=223, Percent_Identity=25.5605381165919, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI19923817, Length=282, Percent_Identity=26.241134751773, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=28.5024154589372, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI142976729, Length=223, Percent_Identity=25.5605381165919, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157739938, Length=197, Percent_Identity=28.9340101522843, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI10190704, Length=205, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=25.7936507936508, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40807363, Length=199, Percent_Identity=26.1306532663317, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723191, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI25282469, Length=220, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI59889578, Length=174, Percent_Identity=24.7126436781609, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4503817, Length=198, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4557649, Length=211, Percent_Identity=25.5924170616114, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI66933014, Length=205, Percent_Identity=26.3414634146341, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=201, Percent_Identity=30.3482587064677, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082100, Length=218, Percent_Identity=29.3577981651376, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787905, Length=218, Percent_Identity=28.4403669724771, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787526, Length=211, Percent_Identity=26.5402843601896, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788459, Length=267, Percent_Identity=25.8426966292135, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789208, Length=202, Percent_Identity=23.7623762376238, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790717, Length=196, Percent_Identity=25, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=25.5102040816327, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787820, Length=150, Percent_Identity=30.6666666666667, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI2367175, Length=200, Percent_Identity=28, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=293, Percent_Identity=31.740614334471, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17564282, Length=201, Percent_Identity=27.363184079602, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=207, Percent_Identity=27.536231884058, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=202, Percent_Identity=25.7425742574257, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=207, Percent_Identity=28.0193236714976, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=203, Percent_Identity=25.615763546798, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=250, Percent_Identity=26.4, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=206, Percent_Identity=25.7281553398058, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=198, Percent_Identity=25.7575757575758, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=26.2626262626263, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=201, Percent_Identity=24.3781094527363, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=215, Percent_Identity=27.906976744186, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=215, Percent_Identity=26.046511627907, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=187, Percent_Identity=26.2032085561497, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=215, Percent_Identity=26.9767441860465, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=294, Percent_Identity=31.9727891156463, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI18859837, Length=249, Percent_Identity=37.7510040160643, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI23397609, Length=201, Percent_Identity=27.8606965174129, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281364892, Length=210, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17737361, Length=211, Percent_Identity=27.0142180094787, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357041, Length=203, Percent_Identity=26.1083743842365, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644339, Length=201, Percent_Identity=26.3681592039801, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=28.735632183908, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571526, Length=203, Percent_Identity=27.0935960591133, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=26.2357414448669, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=28.8617886178862, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640492, Length=227, Percent_Identity=23.7885462555066, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221510726, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=207, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=26.7676767676768, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 34443; Mature: 34443

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDNKVALVTGAGAGLGRAYAIMLAERGAKVVLVDQPLSSSESISTYGAQTMPANLALM
CCCCCEEEEEEECCCCCCHHEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCCCCHHHHH
QTYCSIIKLGGDCLYFVLDVSQRDEVNRMVEEVILRWHRIDILINNAGIYGACPFEHIKL
HHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHEEEEEEEECCCEEECCCHHHHHH
EQWQRQLDVDLNGSFYLTQAVWPYMQQQDYGRIMMTTGASALFGDLHQVGFSASKMALVG
HHHHHHCCCCCCCCEEEHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHH
MVNCLSIEGEIHNIRVNSLCPQAVTAMTAKHLASAIQPLFSFESLTATTAFLVSEQAPNG
HHEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
QHLLAGAGSISHGMFVEFQPMYFNEGLFTPDNLAQQWPQLYQSFPVTLHSSGEDKVLSWS
CEEEEECCCCCCCEEEEEECEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCEECHH
QLSALEHHIQID
HHHHHHHHEECC
>Mature Secondary Structure
MRFDNKVALVTGAGAGLGRAYAIMLAERGAKVVLVDQPLSSSESISTYGAQTMPANLALM
CCCCCEEEEEEECCCCCCHHEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCCCCHHHHH
QTYCSIIKLGGDCLYFVLDVSQRDEVNRMVEEVILRWHRIDILINNAGIYGACPFEHIKL
HHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHEEEEEEEECCCEEECCCHHHHHH
EQWQRQLDVDLNGSFYLTQAVWPYMQQQDYGRIMMTTGASALFGDLHQVGFSASKMALVG
HHHHHHCCCCCCCCEEEHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHH
MVNCLSIEGEIHNIRVNSLCPQAVTAMTAKHLASAIQPLFSFESLTATTAFLVSEQAPNG
HHEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
QHLLAGAGSISHGMFVEFQPMYFNEGLFTPDNLAQQWPQLYQSFPVTLHSSGEDKVLSWS
CEEEEECCCCCCCEEEEEECEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCEECHH
QLSALEHHIQID
HHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]