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The map label for this gene is sdaA [H]

Identifier: 160875636

GI number: 160875636

Start: 2982840

End: 2984216

Strand: Direct

Name: sdaA [H]

Synonym: Sbal195_2524

Alternate gene names: 160875636

Gene position: 2982840-2984216 (Clockwise)

Preceding gene: 160875633

Following gene: 160875639

Centisome position: 55.78

GC content: 49.53

Gene sequence:

>1377_bases
ATGATTAGCGTATTTGACATGTTCAAGATCGGCATAGGTCCATCGAGTTCACATACTGTCGGCCCAATGAAAGCGGGCAA
AATTTTTATGCAAAACCTGACTGACTCAGGACTCGTGACCCAGATTGATGAATTAAGAGCCGAGCTCTTTGGCTCCCTAG
GCCAAACAGGCAAAGGCCACGGCACGGGCAAAGCAGTGATTTTAGGCTTAATGGGTGAAGATCCAGAAACCGTAGACACT
GACAGTATCGACGGCATTTTAGAACACGTCTCCAAGGACGAAACCTTAACCCTGCACTGTGGCAAAGTGGTTAAATTTAC
CCGCGAGCAAGGCATTACCTACCACAGACGCAAAACCTTGCCAGCACACGCCAACGCCATGACCTTATACGCTTATTGTA
AAGATGAGTGTATTTTCGAGCGCACTTATTATTCTGTCGGCGGCGGCTTTATCTTAGATGAAGACGAAATCAGCCAACGT
AATGCATCACCTGCATCACCAATTGAAGCGGCCCCTTTTGATTTTGGCAGTGCAGCGCAATTATTAGAATTGTGTGGCGA
GCAAGGTCTGAGCATTTCTTCTTTGATGATGGCGAACGAACTGAGTTTAGCCACAGAAGATGAAGTCAAAGCCAAGCTGT
GGAACATTTGGCAGACGATGAAAACCTGTATCGAACGCGGTTATCAAAAAGAAGGCATTTTACCTGGTGGCTTAAAACTG
CGTCGCCGCGCCCCTGCCCTGTACCGTCGTTTGAAAGCCGAAGGCCGTAACAACGTAGACCCATTAACCGCAATGGATTG
GGTCGATTTATTCGCCCTGTCAGTAAACGAGCAAAATGCGGCCGGCGCTCGCGTCGTAACTGCGCCAACAAACGGCGCCG
CGGGAATTATCCCTGCAGTATTATGCTATTACGATACCTTCGTACAAGAAGTGGATATCGATGTCTGCGCCCGTTACCTG
TTAACCGCCGCCGCGATTGGTATTTTGTACAAGAAGAATGCCTCAATTTCTGGCGCCGAAGTGGGTTGCCAAGGTGAAGT
TGGCGTAGCCTGTTCTATGGCCGCTGGCGCACTGACTGAAATCATGGGCGGCACGATTGAGCACGTTGAAAACGCAGCTG
AAATCGGCATGGAACATAACTTAGGCTTAACCTGCGATCCTGTGGGCGGCCTAGTGCAAGTGCCTTGTATCGAACGTAAT
GCCATGGGCGCGATCAAAGCGATCAACGCCTCTCGTATGGCCCTACGCGGTGACGGTCACCATAAGGTTTCACTGGATAA
AGTGATCAAAACCATGATGGATACCGGCAGAGATATGCGCAGCAAATACAAAGAAACCGCCAAAGGCGGCCTAGCGGTCA
ACATTGTTGAGTGCTAA

Upstream 100 bases:

>100_bases
CCAGAGTTCACGTTGAAGATTAGCGTGCTTCAATCTGCAGAGCGAGCAATCCCATGCACTCAGACTAAAATAATAAACAA
GACACAACAGGACTTCTATC

Downstream 100 bases:

>100_bases
GTGCTGAGTGTTAGTTCACTCCCACTAATCGCTTAAACTGCATCATAAAAAATGCCGCAACTCACTGAGTTGCGGCATTT
TTGTTTGAGCTCATCGGCGT

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQNLTDSGLVTQIDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DSIDGILEHVSKDETLTLHCGKVVKFTREQGITYHRRKTLPAHANAMTLYAYCKDECIFERTYYSVGGGFILDEDEISQR
NASPASPIEAAPFDFGSAAQLLELCGEQGLSISSLMMANELSLATEDEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGARVVTAPTNGAAGIIPAVLCYYDTFVQEVDIDVCARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTEIMGGTIEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAIKAINASRMALRGDGHHKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC

Sequences:

>Translated_458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQNLTDSGLVTQIDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DSIDGILEHVSKDETLTLHCGKVVKFTREQGITYHRRKTLPAHANAMTLYAYCKDECIFERTYYSVGGGFILDEDEISQR
NASPASPIEAAPFDFGSAAQLLELCGEQGLSISSLMMANELSLATEDEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGARVVTAPTNGAAGIIPAVLCYYDTFVQEVDIDVCARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTEIMGGTIEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAIKAINASRMALRGDGHHKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC
>Mature_458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQNLTDSGLVTQIDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DSIDGILEHVSKDETLTLHCGKVVKFTREQGITYHRRKTLPAHANAMTLYAYCKDECIFERTYYSVGGGFILDEDEISQR
NASPASPIEAAPFDFGSAAQLLELCGEQGLSISSLMMANELSLATEDEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGARVVTAPTNGAAGIIPAVLCYYDTFVQEVDIDVCARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTEIMGGTIEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAIKAINASRMALRGDGHHKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=459, Percent_Identity=56.4270152505447, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1789161, Length=459, Percent_Identity=55.119825708061, Blast_Score=512, Evalue=1e-146,
Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=54.7045951859956, Blast_Score=496, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49206; Mature: 49206

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQNLTDSGLVTQIDELRAELFGSLGQTGKGH
CCCHHEEHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEDPETVDTDSIDGILEHVSKDETLTLHCGKVVKFTREQGITYHRRKTL
CCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEHHCCCC
PAHANAMTLYAYCKDECIFERTYYSVGGGFILDEDEISQRNASPASPIEAAPFDFGSAAQ
CCCCCEEEEEEECCCHHHHHHHHHCCCCCEEECHHHHHHCCCCCCCCCCCCCCCCCCHHH
LLELCGEQGLSISSLMMANELSLATEDEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
HHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGARVVTAPTNGAAGIIPAV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYYDTFVQEVDIDVCARYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTIEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAIKAINASRMALRGDGH
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHCCCCCEEEECCCC
HKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQNLTDSGLVTQIDELRAELFGSLGQTGKGH
CCCHHEEHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEDPETVDTDSIDGILEHVSKDETLTLHCGKVVKFTREQGITYHRRKTL
CCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEHHCCCC
PAHANAMTLYAYCKDECIFERTYYSVGGGFILDEDEISQRNASPASPIEAAPFDFGSAAQ
CCCCCEEEEEEECCCHHHHHHHHHCCCCCEEECHHHHHHCCCCCCCCCCCCCCCCCCHHH
LLELCGEQGLSISSLMMANELSLATEDEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
HHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGARVVTAPTNGAAGIIPAV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYYDTFVQEVDIDVCARYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTIEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAIKAINASRMALRGDGH
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHCCCCCEEEECCCC
HKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]