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The map label for this gene is dmsB [H]

Identifier: 160875340

GI number: 160875340

Start: 2643093

End: 2643770

Strand: Reverse

Name: dmsB [H]

Synonym: Sbal195_2227

Alternate gene names: 160875340

Gene position: 2643770-2643093 (Counterclockwise)

Preceding gene: 160875341

Following gene: 160875339

Centisome position: 49.44

GC content: 40.56

Gene sequence:

>678_bases
ATGACAGAAAAAACTCAATTAGGATTCTATTTCGATAGTAGTAAATGTACAGGTTGTAAGACTTGTCACATTGCTTGTAA
AGACCGAATGGTTGGAAAAATTCGGAACAAAGATGATGTGGCATCAAATGGCGTAGCTTCCCTTCCTGGTATGTTATGGC
GTCGAGTATACGAATACGGTGGAGGAACCTGGAGTCAGAATAGTGATAATAGCTTTGAACAAAACGTATTTGCTTACTAC
ACCTCGATTAGTTGTAACCATTGTTCAGAACCTGTTTGTGTAAAAGCCTGCCCAACAGGAGCGATGCACAAACGCAAGGA
AGATGGTCTGGTATTAGTAGAAGAATCACTTTGTATTGGTTGTCAAAGCTGCTCTAGAGCATGTCCTTACGATGCTCCGC
AAATTGATAGAGATCGTAAAGTAATGACTAAGTGCGATGGTTGCTACGATCGTCTAGCCGAAGGGAAAAAGCCTATTTGT
GTAGAAGGCTGCCCTTTGCGAGCATTAGATTTTGATACGATGGAAAATCTACGGAAAAAATATGGCAATGGGGATGGTCA
CTTTGCTCCTTTACCTTCGCAATCAATAACTTCGCCAAATTTAATTGTAAAAGCCTCTCGAAAATCAAAATCGACAGGCA
ATGATGATGGTAGGGTGTTGAATATACGCGAAGTTTAA

Upstream 100 bases:

>100_bases
TATTAACGCATTGACCAAATACCATCCGTCACCCATTACAAAGGGGAATCCACAACATACCAATCGTGTTCAGGTTGTAA
AAGCTTAGGGGTAATCAAAA

Downstream 100 bases:

>100_bases
TTGCCATCTAAGTTAAGGTGCAATGTAAATTGCACCTTTTAATTATAAAAAGATAAGTTAATCTTTATGAAAAAAATTAA
TCTTGAAACACTCAATGAAT

Product: dimethylsulfoxide reductase subunit B

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTEKTQLGFYFDSSKCTGCKTCHIACKDRMVGKIRNKDDVASNGVASLPGMLWRRVYEYGGGTWSQNSDNSFEQNVFAYY
TSISCNHCSEPVCVKACPTGAMHKRKEDGLVLVEESLCIGCQSCSRACPYDAPQIDRDRKVMTKCDGCYDRLAEGKKPIC
VEGCPLRALDFDTMENLRKKYGNGDGHFAPLPSQSITSPNLIVKASRKSKSTGNDDGRVLNIREV

Sequences:

>Translated_225_residues
MTEKTQLGFYFDSSKCTGCKTCHIACKDRMVGKIRNKDDVASNGVASLPGMLWRRVYEYGGGTWSQNSDNSFEQNVFAYY
TSISCNHCSEPVCVKACPTGAMHKRKEDGLVLVEESLCIGCQSCSRACPYDAPQIDRDRKVMTKCDGCYDRLAEGKKPIC
VEGCPLRALDFDTMENLRKKYGNGDGHFAPLPSQSITSPNLIVKASRKSKSTGNDDGRVLNIREV
>Mature_224_residues
TEKTQLGFYFDSSKCTGCKTCHIACKDRMVGKIRNKDDVASNGVASLPGMLWRRVYEYGGGTWSQNSDNSFEQNVFAYYT
SISCNHCSEPVCVKACPTGAMHKRKEDGLVLVEESLCIGCQSCSRACPYDAPQIDRDRKVMTKCDGCYDRLAEGKKPICV
EGCPLRALDFDTMENLRKKYGNGDGHFAPLPSQSITSPNLIVKASRKSKSTGNDDGRVLNIREV

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=221, Percent_Identity=54.7511312217195, Blast_Score=241, Evalue=3e-65,
Organism=Escherichia coli, GI1787872, Length=221, Percent_Identity=52.9411764705882, Blast_Score=235, Evalue=2e-63,
Organism=Escherichia coli, GI1790326, Length=178, Percent_Identity=32.0224719101124, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789370, Length=202, Percent_Identity=31.1881188118812, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787749, Length=177, Percent_Identity=31.0734463276836, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI226510944, Length=174, Percent_Identity=35.0574712643678, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI2367345, Length=173, Percent_Identity=33.5260115606936, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI2367245, Length=170, Percent_Identity=31.1764705882353, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1787478, Length=91, Percent_Identity=38.4615384615385, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787740, Length=91, Percent_Identity=38.4615384615385, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082179, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789067, Length=188, Percent_Identity=30.3191489361702, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787963, Length=161, Percent_Identity=27.3291925465839, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788811, Length=100, Percent_Identity=35, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 24897; Mature: 24765

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
9.8 %Cys+Met (Translated Protein)
7.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
9.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKTQLGFYFDSSKCTGCKTCHIACKDRMVGKIRNKDDVASNGVASLPGMLWRRVYEYG
CCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHC
GGTWSQNSDNSFEQNVFAYYTSISCNHCSEPVCVKACPTGAMHKRKEDGLVLVEESLCIG
CCCCCCCCCCCHHHCEEEEEEECCCCCCCCCEEEEECCCCHHHCCCCCCEEEEECCHHHC
CQSCSRACPYDAPQIDRDRKVMTKCDGCYDRLAEGKKPICVEGCPLRALDFDTMENLRKK
CHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECHHHHHHHHHH
YGNGDGHFAPLPSQSITSPNLIVKASRKSKSTGNDDGRVLNIREV
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
TEKTQLGFYFDSSKCTGCKTCHIACKDRMVGKIRNKDDVASNGVASLPGMLWRRVYEYG
CCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHC
GGTWSQNSDNSFEQNVFAYYTSISCNHCSEPVCVKACPTGAMHKRKEDGLVLVEESLCIG
CCCCCCCCCCCHHHCEEEEEEECCCCCCCCCEEEEECCCCHHHCCCCCCEEEEECCHHHC
CQSCSRACPYDAPQIDRDRKVMTKCDGCYDRLAEGKKPICVEGCPLRALDFDTMENLRKK
CHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECHHHHHHHHHH
YGNGDGHFAPLPSQSITSPNLIVKASRKSKSTGNDDGRVLNIREV
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8635740 [H]