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The map label for this gene is apbE [H]

Identifier: 160875041

GI number: 160875041

Start: 2297206

End: 2298111

Strand: Direct

Name: apbE [H]

Synonym: Sbal195_1926

Alternate gene names: 160875041

Gene position: 2297206-2298111 (Clockwise)

Preceding gene: 160875040

Following gene: 160875042

Centisome position: 42.96

GC content: 49.34

Gene sequence:

>906_bases
ATGTCGACATCATCCCTAAAAACCGCACTTTATTCGCTGCAACGCCGTGATTGGGGTTATGTGGGCGAATTTAGGGCCAT
GGCGAGTCCCTGTGAAATACTCATTGCATGTGATCAACTCGATATCGCCGACGATATGTTGGATATGGCCGTCACTGAGG
CGCTGCGTATTGAACATAAGTACAGTCGCTTTATTGCGCAGAATTGTCTGTGGCAATTAAACCATGCCTATGGTCATAAG
CAGCTTATTGATGAAGAAACCTGGCAGTTATTGGCTTTTGCCAAACAATGTTTTCAGCTTAGTGATGGATTATTTGATAT
CTCTGCAGGGCCGTTAATGGAGCTGTGGCGCTTTGATCCCAAAGCCCAATTGCCTGAACATGCCCGCATACTTGCCGCGA
AAGCCTTAGTGGGGTTTGAGCGTATCGAGTTTGATTCGCGCCATATTGAGATGCCAACGGGAATGAAATTGGATTTTGGC
GGCGTTGCTAAGGAATATGCAGTCGATAGAGTCGCCTATGAGTTGGCTGAATGTTATCCAGATATTCCTGTACTAGTGAA
TTTTGGTGGCGATATCGCCTGTCCTGTGCCCAAAGTGAACCCATGGCAGGTGGGCATTGAAGATCCTCGCCATCTCGATC
GCGCCGCCAGTGTACTGGCGATCAGTCAGGGCGCATTAGCGACCAGCGGCGATACACGGCGCTTTTTTGAAGTCGATGGA
ATGCGTTACGGCCATATTGTCGATCCGCGTACTGGCTATCCCGTCGTCCATGCGCCGCGCTCCGTGACTGTGTTAGGACC
AAACTGTGTGACCGCTGGAATGCTGGCGACTATGGCCATGCTACAGGGCCAGGATGCGGAAGCATTTTTACAGCAACAAG
ATGTTAAGTTTAGTATTTTCCGTTAA

Upstream 100 bases:

>100_bases
CGTTAAACTGTATGGGTAGCTTAGCTACCCATACTCAATTTACCCCTGAGCTTATTTAAGCTGAATCCCAGTGGGGTGCC
ATGTAAAGAGGTGATTTATG

Downstream 100 bases:

>100_bases
GGGTTCTTTTAAAAGGCTCTGTTAAGGACATTGAATGCGTATTATGTTGGTTGAAGACAATGAGTTATTAGCCCAAGGGA
TTTGCTTAAGTTTGGCAAAG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSTSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHKYSRFIAQNCLWQLNHAYGHK
QLIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDPKAQLPEHARILAAKALVGFERIEFDSRHIEMPTGMKLDFG
GVAKEYAVDRVAYELAECYPDIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDG
MRYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIFR

Sequences:

>Translated_301_residues
MSTSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHKYSRFIAQNCLWQLNHAYGHK
QLIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDPKAQLPEHARILAAKALVGFERIEFDSRHIEMPTGMKLDFG
GVAKEYAVDRVAYELAECYPDIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDG
MRYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIFR
>Mature_300_residues
STSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHKYSRFIAQNCLWQLNHAYGHKQ
LIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDPKAQLPEHARILAAKALVGFERIEFDSRHIEMPTGMKLDFGG
VAKEYAVDRVAYELAECYPDIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDGM
RYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIFR

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=197, Percent_Identity=32.994923857868, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 33678; Mature: 33547

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHK
CCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
YSRFIAQNCLWQLNHAYGHKQLIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHCCCC
KAQLPEHARILAAKALVGFERIEFDSRHIEMPTGMKLDFGGVAKEYAVDRVAYELAECYP
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHHHHCC
DIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDG
CCCEEEECCCCEECCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEEECC
MRYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIF
CEECCEECCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEC
R
C
>Mature Secondary Structure 
STSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHK
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
YSRFIAQNCLWQLNHAYGHKQLIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHCCCC
KAQLPEHARILAAKALVGFERIEFDSRHIEMPTGMKLDFGGVAKEYAVDRVAYELAECYP
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHHHHCC
DIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDG
CCCEEEECCCCEECCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEEECC
MRYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIF
CEECCEECCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]