Click here to switch to the map view.

The map label for this gene is hda [H]

Identifier: 160874938

GI number: 160874938

Start: 2187860

End: 2188570

Strand: Direct

Name: hda [H]

Synonym: Sbal195_1823

Alternate gene names: 160874938

Gene position: 2187860-2188570 (Clockwise)

Preceding gene: 160874937

Following gene: 160874943

Centisome position: 40.92

GC content: 49.79

Gene sequence:

>711_bases
GTGCCCTTAAACTCACCTCTGCAACTCTCGTTACCTGTGCATTTGCCAGACGACGAAACCTTTAACAGTTATTACCCCGC
CGCGGGTAATGATGAGCTTATTCAAAAACTGAGAGCCAATGCCGAAGGGCAGGGTGAAGCCGCCATTTATTTGTGGGGCC
CAGTCAAATCGGGTCGAACCCATTTAATGCACGCCGCTTGCGCCCACGCTAATGAAGTAGAGCGTCGCAGCTTTTATATT
CCCTTAGGCATACATGCGAGTATTTCGACCGCCTTGCTTGAAGGACTAGAACAGTTAGATTTAGTCTGTATCGATGATGT
CGATGCCATCGCCGGTCACCCCGTCTGGGAAGAAGCGATTTTTGATCTCTATAATCGCGTCGCCGAACATAAAAATTGTG
CCTTGGTGGTCAGTGGCAGTTCGTCTCCTGCGGATGCTGGTTTCCTCTTGCCAGATCTCGTTTCACGTATGCAGTGGGGT
TTGAATTATCAACTGCAACCTATGGCTGATGATGAGAAACTTGCCGCCCTGCAACGCCGCGCCGCCATGCGTGGTCTGCA
ATTGCCAGAAGACGTGGGACGTTTTTTGCTGAACCGAATGGCGCGGGATTTACGTACCTTGTTCGATGTATTGGATAAGT
TAGATAAAGCCTCATTAGTGCACCAGCGCAAGCTCACCATTCCCTTTGCCAAAGAGATGCTGCATCTTTAA

Upstream 100 bases:

>100_bases
GGCAAGCCTGTGTATGAATGGCGCTTACCTTAAGATGTTATCGGCCGTGCTTAGCCATGCTAAGCACGGCATTGTTTTTA
TTTGATATTGAGAAGACCGA

Downstream 100 bases:

>100_bases
AAGCATGATTGGATAGAGACGCGGTTTGAGTGGTTTTGAATTAGCCTTGAGCCATGTAAACGCTAAAAAATGTAAAATCC
CTAAAACCTAAAAATCAAAA

Product: DNA replication initiation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MPLNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQKLRANAEGQGEAAIYLWGPVKSGRTHLMHAACAHANEVERRSFYI
PLGIHASISTALLEGLEQLDLVCIDDVDAIAGHPVWEEAIFDLYNRVAEHKNCALVVSGSSSPADAGFLLPDLVSRMQWG
LNYQLQPMADDEKLAALQRRAAMRGLQLPEDVGRFLLNRMARDLRTLFDVLDKLDKASLVHQRKLTIPFAKEMLHL

Sequences:

>Translated_236_residues
MPLNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQKLRANAEGQGEAAIYLWGPVKSGRTHLMHAACAHANEVERRSFYI
PLGIHASISTALLEGLEQLDLVCIDDVDAIAGHPVWEEAIFDLYNRVAEHKNCALVVSGSSSPADAGFLLPDLVSRMQWG
LNYQLQPMADDEKLAALQRRAAMRGLQLPEDVGRFLLNRMARDLRTLFDVLDKLDKASLVHQRKLTIPFAKEMLHL
>Mature_235_residues
PLNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQKLRANAEGQGEAAIYLWGPVKSGRTHLMHAACAHANEVERRSFYIP
LGIHASISTALLEGLEQLDLVCIDDVDAIAGHPVWEEAIFDLYNRVAEHKNCALVVSGSSSPADAGFLLPDLVSRMQWGL
NYQLQPMADDEKLAALQRRAAMRGLQLPEDVGRFLLNRMARDLRTLFDVLDKLDKASLVHQRKLTIPFAKEMLHL

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=234, Percent_Identity=50, Blast_Score=239, Evalue=8e-65,
Organism=Escherichia coli, GI2367267, Length=229, Percent_Identity=23.5807860262009, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 26274; Mature: 26143

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQKLRANAEGQGEAAIYLWGPVKSGRT
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHH
HLMHAACAHANEVERRSFYIPLGIHASISTALLEGLEQLDLVCIDDVDAIAGHPVWEEAI
HHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHCCEEEECCCHHHCCCCHHHHHH
FDLYNRVAEHKNCALVVSGSSSPADAGFLLPDLVSRMQWGLNYQLQPMADDEKLAALQRR
HHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHH
AAMRGLQLPEDVGRFLLNRMARDLRTLFDVLDKLDKASLVHQRKLTIPFAKEMLHL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
PLNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQKLRANAEGQGEAAIYLWGPVKSGRT
CCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHH
HLMHAACAHANEVERRSFYIPLGIHASISTALLEGLEQLDLVCIDDVDAIAGHPVWEEAI
HHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHCCEEEECCCHHHCCCCHHHHHH
FDLYNRVAEHKNCALVVSGSSSPADAGFLLPDLVSRMQWGLNYQLQPMADDEKLAALQRR
HHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHH
AAMRGLQLPEDVGRFLLNRMARDLRTLFDVLDKLDKASLVHQRKLTIPFAKEMLHL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA