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The map label for this gene is hlyB [H]

Identifier: 160874443

GI number: 160874443

Start: 1573456

End: 1575024

Strand: Direct

Name: hlyB [H]

Synonym: Sbal195_1324

Alternate gene names: 160874443

Gene position: 1573456-1575024 (Clockwise)

Preceding gene: 160874441

Following gene: 160874444

Centisome position: 29.43

GC content: 48.63

Gene sequence:

>1569_bases
ATGGAAATACAGCACAAAGTTTTAATTTTTATCAGTTTCACGCTGGTCACTCTAGGGAGTTTATTACTTGCGGGGCTGCA
TCTTCCGAGCATTGTGCAGGCGCTGATCTTGGGTGCAATCACCTCTGGCTTAGTGGTGTGGGTGTGTTTGCGCGCAACTA
AGGCTAAGCTCGACACCGATGAGGCAAATGCTAAGGCATTAAAAGAGCAAAGCCTTCCCGCCCATGATATCAGTGTGCAA
ACCAGTAAAATTGCTATTGGTTCGGCAGAAGTGTCGCATTTTATTGATTTACTGAATAAATCCATTGAATCAAATGGCGA
ACATGCCAGCGCTATTGCGGTTGCCGCAGGGCAATTGAGTCATACCACGGCCCAACTTGGCGATAATGCCGCCGATATTT
TAGGTCAGGCACAAGAGGCCGAGCGCGTTAGCGTGCAGGGGCGCAGCCAAGCCCAAAAAGGTGTGTCGGCTATTCGCTCA
CTGAGTACGGATATTGATACCGCCGCCGAGCAAGTACAGGCGCTTAAGTCGCGAGCCGAAGAAATCCAAAAAATCACCGA
AGTGATTAACTCCGTTGCCGAGCAAACGAATTTGTTGGCGTTAAATGCGGCCATTGAAGCGGCTCGTGCGGGAGAACAGG
GTCGAGGTTTTGCGGTCGTCGCAGACGAAGTACGCAGCCTTGCGGGTAAAACCGCAGGTGCGACCCAAGATATCGGCAAG
ATGCTATTAGAAATCCGCAGCGAAACCGATAAAACCTCTGGGCTGATGGAACGCGTCGTAACGCAAACCGCCGATGTGGT
CGCGGCTATGGGCGAGTTAGACGCGCATTTCACTGAGATTTCGGCCTCTGTGACTCAATCGGCCCATGCGTTAGGTGATA
TGGAAGATTCCCTCAAACAATATAACAACACCACTAATGACATTAGCCGCTCGGTGACTCAAATCCGTGATTCGTTAAAT
TCGACGGGTAAACAGAGTCATAGCGTATCTGAGCAGGCCTTTACTCTATCCTTGACCACCGAGGGCATTTTTAAAGCGCT
GTCTAAATGGGATACACAAACCTTCGATCAGCAGGTTTTGCAATTGGCCAATGTGGCCGCTAAAGCGTGCGGTGACAAGT
TGGCACAAGGTTTAGTTAGCGGCAGTTTTAGCGAGGCAGATTTGTTTAATCCTAAATATCAACCGATTGCCAATACTCAG
CCGCAGAAATACAGCACAGCTTTCGATCGCTATACCGATCAGCATTTTCCAACGATTCAAGAACCCATTCTGGCAAAACA
TAGCGAAATTATTTATGCGGGAGCTGTTGATAAAAAAGGTTATTTTCCGACCCATAATAAACGCTTTAGCCAAGCGCTGA
CGGGCAAGGTCGAAGTCGATATGGTGCATAATCGAACCAAACGCTTGTTTAATGATCCGACGGGGATCCGCTGCGGCGCC
CATACAGAACCTGTATTACTGCAAACCTACAAACGGGATACGGGCGAAGTGATGCATGACTTGTCTGTGCCCATTTTTGT
GAATGGTAAACATTGGGGCGGATTTAGAGTGGGATTTAAGGCTAAGTGA

Upstream 100 bases:

>100_bases
CTTCTTAGTCAGCTGTAATTGATTGCAGCTGAACGAGGGCGAATGATTCGACTCTTAGCATTTCCCTTTCATTTTTACCT
TGCGCAGTTACGGGAAGTAT

Downstream 100 bases:

>100_bases
ATAATAGATAATCAAATTTAGTTTATTTACTCTAAAAAATGCATAAAAATGCATCTTGCTATGTGTTGTACTTGTGATCC
GTGGTGGGTAATTGATTAAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTDEANAKALKEQSLPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLSHTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVSAIRS
LSTDIDTAAEQVQALKSRAEEIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQYNNTTNDISRSVTQIRDSLN
STGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVLQLANVAAKACGDKLAQGLVSGSFSEADLFNPKYQPIANTQ
PQKYSTAFDRYTDQHFPTIQEPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK

Sequences:

>Translated_522_residues
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTDEANAKALKEQSLPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLSHTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVSAIRS
LSTDIDTAAEQVQALKSRAEEIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQYNNTTNDISRSVTQIRDSLN
STGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVLQLANVAAKACGDKLAQGLVSGSFSEADLFNPKYQPIANTQ
PQKYSTAFDRYTDQHFPTIQEPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK
>Mature_522_residues
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTDEANAKALKEQSLPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLSHTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVSAIRS
LSTDIDTAAEQVQALKSRAEEIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQYNNTTNDISRSVTQIRDSLN
STGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVLQLANVAAKACGDKLAQGLVSGSFSEADLFNPKYQPIANTQ
PQKYSTAFDRYTDQHFPTIQEPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=239, Percent_Identity=36.8200836820084, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788194, Length=234, Percent_Identity=32.4786324786325, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1789453, Length=231, Percent_Identity=32.4675324675325, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367378, Length=203, Percent_Identity=33.4975369458128, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788195, Length=203, Percent_Identity=34.9753694581281, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 56234; Mature: 56234

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTD
CCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EANAKALKEQSLPAHDISVQTSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLS
HHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVSAIRSLSTDIDTAAEQVQALKSRAE
HHHHHHCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
HHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHH
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YNNTTNDISRSVTQIRDSLNSTGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVL
HCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEEEEECHHHHHHHHHHHCHHHHHHHHH
QLANVAAKACGDKLAQGLVSGSFSEADLFNPKYQPIANTQPQKYSTAFDRYTDQHFPTIQ
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
EPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCC
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK
CCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCC
>Mature Secondary Structure
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTD
CCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EANAKALKEQSLPAHDISVQTSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLS
HHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVSAIRSLSTDIDTAAEQVQALKSRAE
HHHHHHCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
HHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHH
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YNNTTNDISRSVTQIRDSLNSTGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVL
HCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEEEEECHHHHHHHHHHHCHHHHHHHHH
QLANVAAKACGDKLAQGLVSGSFSEADLFNPKYQPIANTQPQKYSTAFDRYTDQHFPTIQ
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
EPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCC
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK
CCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]