Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 160874398

GI number: 160874398

Start: 1517859

End: 1518875

Strand: Direct

Name: era [H]

Synonym: Sbal195_1279

Alternate gene names: 160874398

Gene position: 1517859-1518875 (Clockwise)

Preceding gene: 160874397

Following gene: 160874399

Centisome position: 28.39

GC content: 48.18

Gene sequence:

>1017_bases
ATGACCAAAAAAACAGACTTGTCAGGTATCGATGCTGCAAAAGCGGCAACTGAGCCGAGTTTAGATGAATTACTGGCAAG
GATGAATGCGGCCGCGCCAACGCCGTCGGCCCATTACGATGTCACTTATTGCGGCATGGTGGCGATCATTGGTCGCCCTA
ACGTCGGTAAATCGACGTTAATCAATCGTTTGCTTGGCCAGAAGGTGAGTATTACTTCTAAAAAGCCGCAAACGACGCGC
CACCGTATCATGGGTATTCATACCGATGGTCCTAAGCAAATCGTGTTTATCGATACACCGGGTTTGCACATTGAAGAGCA
GCGGGCGATTAACCGCCTGATGAACCGCGCAGCGGCCAGTTCGCTTGCCGATGTGGCTATGGTCATTTTCGTGGTCGATG
GCATGACATGGACCGCCGATGATGAGATGGTGCTCAGCAAGTTACGCCGTGGCGGCGAAGAGCGTCAGACGATTCTGGCG
ATCAACAAAGTCGATAATATCAAAGACAAAGAATCATTATTCCCGTATTTGGAAGAAGTCGCCAAAAAATATCCTTTCGA
TGAAATTTTGCCGATTTCAGCCAGCAAGGGCACTAACGTCCAGCGAATTTTAGAGCTGGCAGCAGCGTCGATTCCTGAAG
GACCTTTCTTCTTCCCTGAAGATTATGTTACTGACCGTTCGCAACGTTTTATGGCGTCGGAAATTGTGCGTGAAAAACTG
ATGCGCTTCCTCGGTGATGAATTACCCTATGATGCGACGGTTGAGATCGAACAGTTTAAGATGATGGAAAATGGCGTTTA
TCAAATTAATGCCCTGATCCTCGTTGAGCGTGAAGGTCAAAAACGTATGGTGATCGGTAGCAAGGGCGAACGTATTCGTA
CTATTGCGACTCAAGCCCGCTTAGACATGGAAACCTTGTTTGATAATAAAGTCTTCCTTGAAGTGTGGGTGAAAGTGAAA
TCTGGTTGGGCCGATGATGAACGCGCCCTGCGTAGCTTAGGTTACGGCGACGATTAA

Upstream 100 bases:

>100_bases
GTCGTATTGAAGACTTGAGCCAAAGCGTCATTGGTGTGGCGAGTTCACGCCGTAAAGCCGAGCAAATCGCGGCCGCTCAA
GTATTGGAGTTACTAAAGAA

Downstream 100 bases:

>100_bases
GCATTAATTCCAGCGAGCGCGCTTACCGATGAAACGTGGTTATGTTCTGCATCATCGTCCGTATCGAGAGTCCAGTGTTT
TAGTTAACCTCTTAGTTGAC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTKKTDLSGIDAAKAATEPSLDELLARMNAAAPTPSAHYDVTYCGMVAIIGRPNVGKSTLINRLLGQKVSITSKKPQTTR
HRIMGIHTDGPKQIVFIDTPGLHIEEQRAINRLMNRAAASSLADVAMVIFVVDGMTWTADDEMVLSKLRRGGEERQTILA
INKVDNIKDKESLFPYLEEVAKKYPFDEILPISASKGTNVQRILELAAASIPEGPFFFPEDYVTDRSQRFMASEIVREKL
MRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQARLDMETLFDNKVFLEVWVKVK
SGWADDERALRSLGYGDD

Sequences:

>Translated_338_residues
MTKKTDLSGIDAAKAATEPSLDELLARMNAAAPTPSAHYDVTYCGMVAIIGRPNVGKSTLINRLLGQKVSITSKKPQTTR
HRIMGIHTDGPKQIVFIDTPGLHIEEQRAINRLMNRAAASSLADVAMVIFVVDGMTWTADDEMVLSKLRRGGEERQTILA
INKVDNIKDKESLFPYLEEVAKKYPFDEILPISASKGTNVQRILELAAASIPEGPFFFPEDYVTDRSQRFMASEIVREKL
MRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQARLDMETLFDNKVFLEVWVKVK
SGWADDERALRSLGYGDD
>Mature_337_residues
TKKTDLSGIDAAKAATEPSLDELLARMNAAAPTPSAHYDVTYCGMVAIIGRPNVGKSTLINRLLGQKVSITSKKPQTTRH
RIMGIHTDGPKQIVFIDTPGLHIEEQRAINRLMNRAAASSLADVAMVIFVVDGMTWTADDEMVLSKLRRGGEERQTILAI
NKVDNIKDKESLFPYLEEVAKKYPFDEILPISASKGTNVQRILELAAASIPEGPFFFPEDYVTDRSQRFMASEIVREKLM
RFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQARLDMETLFDNKVFLEVWVKVKS
GWADDERALRSLGYGDD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=326, Percent_Identity=26.0736196319018, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=65.2173913043478, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI87082120, Length=161, Percent_Identity=31.6770186335404, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646434, Length=303, Percent_Identity=26.7326732673267, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37888; Mature: 37757

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKTDLSGIDAAKAATEPSLDELLARMNAAAPTPSAHYDVTYCGMVAIIGRPNVGKSTL
CCCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCCHHHH
INRLLGQKVSITSKKPQTTRHRIMGIHTDGPKQIVFIDTPGLHIEEQRAINRLMNRAAAS
HHHHHCCCEEECCCCCCCCHHHEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
SLADVAMVIFVVDGMTWTADDEMVLSKLRRGGEERQTILAINKVDNIKDKESLFPYLEEV
HHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHH
AKKYPFDEILPISASKGTNVQRILELAAASIPEGPFFFPEDYVTDRSQRFMASEIVREKL
HHHCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
MRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQAR
HHHHCCCCCCCCEEHHHHHHHHHCCCEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHH
LDMETLFDNKVFLEVWVKVKSGWADDERALRSLGYGDD
HHHHHHHCCCEEEEEEEHHHCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
TKKTDLSGIDAAKAATEPSLDELLARMNAAAPTPSAHYDVTYCGMVAIIGRPNVGKSTL
CCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCCHHHH
INRLLGQKVSITSKKPQTTRHRIMGIHTDGPKQIVFIDTPGLHIEEQRAINRLMNRAAAS
HHHHHCCCEEECCCCCCCCHHHEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
SLADVAMVIFVVDGMTWTADDEMVLSKLRRGGEERQTILAINKVDNIKDKESLFPYLEEV
HHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHH
AKKYPFDEILPISASKGTNVQRILELAAASIPEGPFFFPEDYVTDRSQRFMASEIVREKL
HHHCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
MRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQAR
HHHHCCCCCCCCEEHHHHHHHHHCCCEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHH
LDMETLFDNKVFLEVWVKVKSGWADDERALRSLGYGDD
HHHHHHHCCCEEEEEEEHHHCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA