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The map label for this gene is rnc

Identifier: 160874397

GI number: 160874397

Start: 1517182

End: 1517862

Strand: Direct

Name: rnc

Synonym: Sbal195_1278

Alternate gene names: 160874397

Gene position: 1517182-1517862 (Clockwise)

Preceding gene: 160874396

Following gene: 160874398

Centisome position: 28.37

GC content: 44.79

Gene sequence:

>681_bases
ATGGAACCGATTAAAAATTTGCCACGTTTGTGTCGTACTTTAAGTTATGAGTTCAAGAATATTGAGCTGTTGACTCAAGC
GCTGACCCACAGAAGTGCGGCAAATAAACACAATGAACGCTTAGAGTTTTTAGGTGATTCAATTTTATCTATTGTGATTT
CTGATGCCTTATATCATCAGTTTCCGAAGGCGACCGAAGGCGATTTAAGCCGGATGCGCGCTACCTTAGTGCGCGGTGAT
ACCTTAACGATCATCGCCCAAGAATTTAAGCTCGGCGATTATTTATATCTTGGTCCTGGTGAATTAAAAAGTGGCGGATT
TAGACGCGAGTCGATTCTTGCCGATGCGGTTGAAGCCATTATTGGCGCCGTTTATCTTGATTCCGATCTCGAAGTTTGCC
GTGCATTACTGCTGAAATGGTATGCCGAGCGTTTGGCCGAAATCCAACCCGGGATCAGCCAGAAAGACGCGAAAACCTTA
CTGCAAGAACATTTACAAGGGTTTAAAAAGCCACTGCCTGATTACCAAGTAATCAACATAGAAGGCGATGCCCACGATCA
GACATTTACCGTTGAATGTCGTATTGAAGACTTGAGCCAAAGCGTCATTGGTGTGGCGAGTTCACGCCGTAAAGCCGAGC
AAATCGCGGCCGCTCAAGTATTGGAGTTACTAAAGAAATGA

Upstream 100 bases:

>100_bases
ATTTGGATTAGTTTTGAATTTGACCGCTCAAAAGCCGACTTCCTCCCAACTTGGGTACCGAGCGGCGTGCGTTTTGAGCG
TGTAGGTGGAATTAAATAGC

Downstream 100 bases:

>100_bases
CCAAAAAAACAGACTTGTCAGGTATCGATGCTGCAAAAGCGGCAACTGAGCCGAGTTTAGATGAATTACTGGCAAGGATG
AATGCGGCCGCGCCAACGCC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEPIKNLPRLCRTLSYEFKNIELLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGD
TLTIIAQEFKLGDYLYLGPGELKSGGFRRESILADAVEAIIGAVYLDSDLEVCRALLLKWYAERLAEIQPGISQKDAKTL
LQEHLQGFKKPLPDYQVINIEGDAHDQTFTVECRIEDLSQSVIGVASSRRKAEQIAAAQVLELLKK

Sequences:

>Translated_226_residues
MEPIKNLPRLCRTLSYEFKNIELLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGD
TLTIIAQEFKLGDYLYLGPGELKSGGFRRESILADAVEAIIGAVYLDSDLEVCRALLLKWYAERLAEIQPGISQKDAKTL
LQEHLQGFKKPLPDYQVINIEGDAHDQTFTVECRIEDLSQSVIGVASSRRKAEQIAAAQVLELLKK
>Mature_226_residues
MEPIKNLPRLCRTLSYEFKNIELLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGD
TLTIIAQEFKLGDYLYLGPGELKSGGFRRESILADAVEAIIGAVYLDSDLEVCRALLLKWYAERLAEIQPGISQKDAKTL
LQEHLQGFKKPLPDYQVINIEGDAHDQTFTVECRIEDLSQSVIGVASSRRKAEQIAAAQVLELLKK

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Homo sapiens, GI155030236, Length=215, Percent_Identity=30.2325581395349, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI155030234, Length=215, Percent_Identity=30.2325581395349, Blast_Score=95, Evalue=5e-20,
Organism=Escherichia coli, GI1788920, Length=211, Percent_Identity=64.4549763033175, Blast_Score=280, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17506883, Length=189, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193202651, Length=189, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17137682, Length=232, Percent_Identity=30.1724137931034, Blast_Score=94, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_SHEB2 (B8EBQ2)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359020.1
- ProteinModelPortal:   B8EBQ2
- SMR:   B8EBQ2
- GeneID:   7087890
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_3112
- HOGENOM:   HBG744556
- OMA:   ALTHKSF
- ProtClustDB:   PRK00102
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 25353; Mature: 25353

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIKNLPRLCRTLSYEFKNIELLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPKATEGDLSRMRATLVRGDTLTIIAQEFKLGDYLYLGPGELKSGGFRRESILADAVEAI
CCCCCCHHHHHHHHHHHCCCCCEEEEHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
IGAVYLDSDLEVCRALLLKWYAERLAEIQPGISQKDAKTLLQEHLQGFKKPLPDYQVINI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
EGDAHDQTFTVECRIEDLSQSVIGVASSRRKAEQIAAAQVLELLKK
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEPIKNLPRLCRTLSYEFKNIELLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPKATEGDLSRMRATLVRGDTLTIIAQEFKLGDYLYLGPGELKSGGFRRESILADAVEAI
CCCCCCHHHHHHHHHHHCCCCCEEEEHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
IGAVYLDSDLEVCRALLLKWYAERLAEIQPGISQKDAKTLLQEHLQGFKKPLPDYQVINI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
EGDAHDQTFTVECRIEDLSQSVIGVASSRRKAEQIAAAQVLELLKK
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA