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The map label for this gene is rppH

Identifier: 160874380

GI number: 160874380

Start: 1500888

End: 1501412

Strand: Direct

Name: rppH

Synonym: Sbal195_1261

Alternate gene names: 160874380

Gene position: 1500888-1501412 (Clockwise)

Preceding gene: 160874377

Following gene: 160874381

Centisome position: 28.07

GC content: 46.48

Gene sequence:

>525_bases
GTGATTGATAGCGACGGCTTTCGCGCAAATGTGGGCATTATAATTTGTAACAGATATGGCCAAGTCATGTGGGCCAGACG
CTTCGGTCAACACTCATGGCAATTTCCTCAAGGTGGTGTCGATGATGGCGAGACAGCAGAAGAGGCAATGTACCGTGAGC
TATATGAAGAAGTGGGCCTAAGACCCGAACACGTGCATATCCTAACCTCGACCCGTTCTTGGTTACGCTATCGTTTGCCA
AAGCGTTTAGTCAGGCAAGACAGTAAACCTGTGTGTATTGGGCAAAAACAAAAGTGGTTTCTGTTACAACTGAAAAGCCA
AGATAGTGCGATTAATTTGAGTTCCTCTGGGCATCCTGAATTTGACGATTGGCGCTGGGTAAGTTATTGGTATCCTGTGC
GGCAAGTCGTGTCATTTAAGCGTGATGTTTATCGTAAGGTGATGAAAGAGTTTGCGGTAACGGCATTGTCATTCCAGACC
CTAGAAATACCTAGGAAACGGGGAAGGCAAAAAACAACGGGCTGA

Upstream 100 bases:

>100_bases
TGTGATTTTATCCAAGACCTAGGGTGAAATAGAGGTTTGCTGAGAGACTAGCTTTATGAAACAATCAGTTTATTAAAATT
TAATGTGATTTGGAGTCCAT

Downstream 100 bases:

>100_bases
TTTTCAAAAGAGGATTGAAAACAGTGTTAAATACGCTTAGGGATATTACTCAGGCTGTGGCATCTGCCCACAGTTTGGAA
ACCGCATTAGAAGTCTTAGT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGETAEEAMYRELYEEVGLRPEHVHILTSTRSWLRYRLP
KRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQT
LEIPRKRGRQKTTG

Sequences:

>Translated_174_residues
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGETAEEAMYRELYEEVGLRPEHVHILTSTRSWLRYRLP
KRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQT
LEIPRKRGRQKTTG
>Mature_174_residues
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGETAEEAMYRELYEEVGLRPEHVHILTSTRSWLRYRLP
KRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQT
LEIPRKRGRQKTTG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=159, Percent_Identity=76.7295597484277, Blast_Score=264, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_SHEB2 (B8EBR9)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359037.1
- ProteinModelPortal:   B8EBR9
- SMR:   B8EBR9
- GeneID:   7087907
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_3129
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- ProtClustDB:   PRK00714
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20574; Mature: 20574

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGETAEEAMYRELYEEVGL
CCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
RPEHVHILTSTRSWLRYRLPKRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPE
CCCEEEEEECHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCEEECCCCCCCC
FDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQTLEIPRKRGRQKTTG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCC
>Mature Secondary Structure
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGETAEEAMYRELYEEVGL
CCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
RPEHVHILTSTRSWLRYRLPKRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPE
CCCEEEEEECHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCEEECCCCCCCC
FDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQTLEIPRKRGRQKTTG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA