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The map label for this gene is ung [H]

Identifier: 160874187

GI number: 160874187

Start: 1266547

End: 1267212

Strand: Direct

Name: ung [H]

Synonym: Sbal195_1067

Alternate gene names: 160874187

Gene position: 1266547-1267212 (Clockwise)

Preceding gene: 160874184

Following gene: 160874189

Centisome position: 23.69

GC content: 48.5

Gene sequence:

>666_bases
GTGACTCAGGCGACATGGCAAACATTTATCGATGAGCAAAGGGCTTTGCCTTATTTTCAGCAACTAAGTGCGTTTGTAGA
CAATGAACGCAGGGCTGGGAAAGTGGTTTATCCCCCCGAAGCCGATGTTTTTAATGCCTTTACTATGACTCCGCTTGAAA
AGGTCAAAGTGGTATTGATTGGCCAAGATCCCTATCACGGCCCAGATCAAGCCCATGGTTTATGCTTTTCGGTCAAACGC
GGTATTAAACCGCCGCCTTCCTTAGCCAATATGTACAAGGAATTAGCGACGGATATTGATGGCTTTACCATTCCATCCCA
CGGGGATTTATCCGCATGGGCGGAGCAGGGGATATTAATGCTCAATACGGTATTAACCGTTGAGCAAGGTAAGGCGCACT
CCCATGCCAAAGCAGGCTGGGAAGTGTTTACTGCTGCCGCGCTGGAATTATTAAATCGTCAGACACAGCCGATTATCTTC
GTGCTTTGGGGCAGTCATGCCATCAAAAAAGGTCAAGTGATTAACGCACCGCAACATCAAGTGCTCACTGGGCCGCATCC
TTCACCTTTATCGGCCTATCGGGGTTTCTTTGGCTGTGGGCATTTTTCTCAAGTGAATCAATTATTACTTGAGCGGGGCG
AAGCGCCGATCCGCTGGCAGGTTTAA

Upstream 100 bases:

>100_bases
ACATAGCCGTATCACTTATCGACAAGCATAACCTTCAAACTTGCCATTCTACAGCAGGGCTTTTAAGCTAACCCGATAAT
AGGATTGAGGAAGTAAAATC

Downstream 100 bases:

>100_bases
TCTTAGGATTGCGGATTTGAGGCAATAAAAAAGGTCTTACTGAGTAAGACCTTTTCTTTGGGCTAAAAACGGATTAGCGA
GTGATCAGTGATTACGGTCG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTQATWQTFIDEQRALPYFQQLSAFVDNERRAGKVVYPPEADVFNAFTMTPLEKVKVVLIGQDPYHGPDQAHGLCFSVKR
GIKPPPSLANMYKELATDIDGFTIPSHGDLSAWAEQGILMLNTVLTVEQGKAHSHAKAGWEVFTAAALELLNRQTQPIIF
VLWGSHAIKKGQVINAPQHQVLTGPHPSPLSAYRGFFGCGHFSQVNQLLLERGEAPIRWQV

Sequences:

>Translated_221_residues
MTQATWQTFIDEQRALPYFQQLSAFVDNERRAGKVVYPPEADVFNAFTMTPLEKVKVVLIGQDPYHGPDQAHGLCFSVKR
GIKPPPSLANMYKELATDIDGFTIPSHGDLSAWAEQGILMLNTVLTVEQGKAHSHAKAGWEVFTAAALELLNRQTQPIIF
VLWGSHAIKKGQVINAPQHQVLTGPHPSPLSAYRGFFGCGHFSQVNQLLLERGEAPIRWQV
>Mature_220_residues
TQATWQTFIDEQRALPYFQQLSAFVDNERRAGKVVYPPEADVFNAFTMTPLEKVKVVLIGQDPYHGPDQAHGLCFSVKRG
IKPPPSLANMYKELATDIDGFTIPSHGDLSAWAEQGILMLNTVLTVEQGKAHSHAKAGWEVFTAAALELLNRQTQPIIFV
LWGSHAIKKGQVINAPQHQVLTGPHPSPLSAYRGFFGCGHFSQVNQLLLERGEAPIRWQV

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=216, Percent_Identity=53.7037037037037, Blast_Score=248, Evalue=3e-66,
Organism=Homo sapiens, GI6224979, Length=216, Percent_Identity=53.7037037037037, Blast_Score=247, Evalue=5e-66,
Organism=Escherichia coli, GI1788934, Length=218, Percent_Identity=57.3394495412844, Blast_Score=270, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI17556304, Length=220, Percent_Identity=45.9090909090909, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6323620, Length=233, Percent_Identity=44.6351931330472, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24540; Mature: 24409

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQATWQTFIDEQRALPYFQQLSAFVDNERRAGKVVYPPEADVFNAFTMTPLEKVKVVLI
CCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHCCCHHHEEEEEE
GQDPYHGPDQAHGLCFSVKRGIKPPPSLANMYKELATDIDGFTIPSHGDLSAWAEQGILM
ECCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCEEE
LNTVLTVEQGKAHSHAKAGWEVFTAAALELLNRQTQPIIFVLWGSHAIKKGQVINAPQHQ
EHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCCCCC
VLTGPHPSPLSAYRGFFGCGHFSQVNQLLLERGEAPIRWQV
EECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure 
TQATWQTFIDEQRALPYFQQLSAFVDNERRAGKVVYPPEADVFNAFTMTPLEKVKVVLI
CCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHCCCHHHEEEEEE
GQDPYHGPDQAHGLCFSVKRGIKPPPSLANMYKELATDIDGFTIPSHGDLSAWAEQGILM
ECCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCEEE
LNTVLTVEQGKAHSHAKAGWEVFTAAALELLNRQTQPIIFVLWGSHAIKKGQVINAPQHQ
EHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCCCCC
VLTGPHPSPLSAYRGFFGCGHFSQVNQLLLERGEAPIRWQV
EECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]