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The map label for this gene is leuE [H]

Identifier: 160874184

GI number: 160874184

Start: 1264698

End: 1265312

Strand: Direct

Name: leuE [H]

Synonym: Sbal195_1064

Alternate gene names: 160874184

Gene position: 1264698-1265312 (Clockwise)

Preceding gene: 160874183

Following gene: 160874187

Centisome position: 23.65

GC content: 48.78

Gene sequence:

>615_bases
ATGAGTTTTAGTACTTGGTTAGGTTTATTGGCGATTTGTTGTTTGGGGGCTATGTCGCCGGGCCCAAGTTTAGCTATGGT
GGTGCGCCATACCTTAGGCGGTGGACGGGGCAAGGGCATAGTGTGTGCGTGGGCACATTCGATAGGCATTGGGATTTATG
CGTTGGTGACGTTACTCGGCTTAGCCGTCGTACTTAAAAAGGCGCCCTTAGTCTTTAATGGCATTGCGATTCTCGGTGCT
TTGTATCTGGCTTGGATGGGAGTTCAGGCGCTGCGTTCCAAGGGCGGTATGCAAGCTAAATTGGCCGCAGGGGAGGCGAC
AGATACCTTGACCGCAGCCCGTGATGGTATCGCCATTTCCTTATTCAATCCTAAAATCATGCTATTTTTCCTCGCATTAT
TCAGCCAATTCGTGATGGTGGCCGACAGCATGACAGCTAAAGCCTTAATCGTTTTTACCCCATTAGTGGTCGATGGCCTT
TGGTACACGCTTATTGCTTTGTTGTTGTCACACTCAAGCGTGTTGCCTAAGTTACGGGAAAAGGCTGGGTTAATTGATAA
GTTGTCTGGCGTGGTATTGATACTGCTAGCAATCCGCGTGGTATATACGCTTTAA

Upstream 100 bases:

>100_bases
TAACGCCTTAATGGCGCAATGCTAGAATAGCAAGCAAGTTTAAGGCCCCAGAGTTTAACTACATCAAAGGGGCCTTTTTA
TTCGGCGTAAGGTGTGTTCA

Downstream 100 bases:

>100_bases
TTATTTATTGCAGGTAATTTGTTTCAACAAACAAAAACGCCATCAATCGATGGCGTTTTTTATGTTATCGCTATGCATGA
AGGGCGTGCTTAGCCTTTAA

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSFSTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIVCAWAHSIGIGIYALVTLLGLAVVLKKAPLVFNGIAILGA
LYLAWMGVQALRSKGGMQAKLAAGEATDTLTAARDGIAISLFNPKIMLFFLALFSQFVMVADSMTAKALIVFTPLVVDGL
WYTLIALLLSHSSVLPKLREKAGLIDKLSGVVLILLAIRVVYTL

Sequences:

>Translated_204_residues
MSFSTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIVCAWAHSIGIGIYALVTLLGLAVVLKKAPLVFNGIAILGA
LYLAWMGVQALRSKGGMQAKLAAGEATDTLTAARDGIAISLFNPKIMLFFLALFSQFVMVADSMTAKALIVFTPLVVDGL
WYTLIALLLSHSSVLPKLREKAGLIDKLSGVVLILLAIRVVYTL
>Mature_203_residues
SFSTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIVCAWAHSIGIGIYALVTLLGLAVVLKKAPLVFNGIAILGAL
YLAWMGVQALRSKGGMQAKLAAGEATDTLTAARDGIAISLFNPKIMLFFLALFSQFVMVADSMTAKALIVFTPLVVDGLW
YTLIALLLSHSSVLPKLREKAGLIDKLSGVVLILLAIRVVYTL

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786522, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788099, Length=134, Percent_Identity=26.865671641791, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21469; Mature: 21338

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIVCAWAHSIGIGIYALVTLLG
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LAVVLKKAPLVFNGIAILGALYLAWMGVQALRSKGGMQAKLAAGEATDTLTAARDGIAIS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCEEEE
LFNPKIMLFFLALFSQFVMVADSMTAKALIVFTPLVVDGLWYTLIALLLSHSSVLPKLRE
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
KAGLIDKLSGVVLILLAIRVVYTL
HHCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFSTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIVCAWAHSIGIGIYALVTLLG
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LAVVLKKAPLVFNGIAILGALYLAWMGVQALRSKGGMQAKLAAGEATDTLTAARDGIAIS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCEEEE
LFNPKIMLFFLALFSQFVMVADSMTAKALIVFTPLVVDGLWYTLIALLLSHSSVLPKLRE
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
KAGLIDKLSGVVLILLAIRVVYTL
HHCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA