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The map label for this gene is atoC [H]

Identifier: 160874154

GI number: 160874154

Start: 1230571

End: 1232082

Strand: Direct

Name: atoC [H]

Synonym: Sbal195_1034

Alternate gene names: 160874154

Gene position: 1230571-1232082 (Clockwise)

Preceding gene: 160874153

Following gene: 160874155

Centisome position: 23.01

GC content: 51.46

Gene sequence:

>1512_bases
ATGGATACTATCCTCATCGTCGACGACAATCACGCCATCTGCCAAGCCCTAGGTTTGATGCTAGAGCTTAATGATTATCG
GGTGCTGACTTGCCATAGTCCGGAGGACGCCCTTGGATTATTGGCGACGCAAGATGTGGATTTAGTGATCCAAGATATGA
ACTTTACTCGGGATACCACGTCGGGTGAGGAAGGCAAGCAGTTGTTTTACGCCCTGCGCGAACGCCAAGGGGATCTGCCG
ATCATTTTGATGACGGCGTGGACCCAGCTCGAAACGGCGGTTGAATTAGTCAAAGCGGGCGCCGCCGATTATATGGGTAA
ACCTTGGGATGACGCTAAGGTACTCAATAGCATCACCAATTTGATTGCGCTTTATAAACTCTCCCGTGCTAACCATCGTC
TCGAGCGGGTGAATCATCAACGCCAAGTGGCGTTCGCCGATGCGGACCTCTGCGGGATTGTCTTTGGCAGCGGCGCGATG
CAGCGTTGCATTGATTTAGCCTTGCAACTGGCGCGATCCGATGTGTCGGTCTTAATCACTGGCCCCAATGGCGCGGGTAA
AGACAAGCTTGCCGATATTCTCCATGCTAATTCTCCCTTAAAAAACAAACCCTTTATCAAGGTCAATGTCGGCGCCTTGC
CGATGGATTTATTAGAGGCAGAGTTGTTTGGTGCCGAGGCGGGGGCTTTTACGGGGGCGACTAAAGCGCGTATTGGTCGC
TTTGAAGCGGCCGACGGCGGCACACTGTTTTTAGATGAAATCGGTAACTTGCCCTTATCTGGCCAAGTAAAACTGCTGCG
CGTGCTGCAAACCGGTGAATTTGAACGCTTAGGTAGCCATAAAACCCAAAAAGTGAAAGTGCGGGTGATCAGTGCGACCA
ATGCGGATCTGGCCCAAGATATTGCCGAAGGGCGTTTTCGTGAGGATTTGTTTTACCGCTTAAATGTGATTGAACTGGCG
CTATCGCCGCTGAATCAACGCACCGATGATATTTTGCCTTTAGTGCAGCATTTTATCGGTAGCGATTTTAGCTTGAGTAA
GCCCGCATTGCAGGCGTTGTTGCACCATCGCTGGCCGGGTAATGTGCGTGAGCTGGAAAACGCCTGTAAGCGAGCGGTAT
TGTTGGCAAAAAGCCATGTATTGACTGAGGCTGACTTTGGCTTGGCACCTGTCGTGAGTGCTGCAAGATCTGCGACTTCC
TATATTTCTGCAGCTTCTGAGCCGCGACGCTTAGATCAGCGACAGTCCGATCCGCGCATCTTTGAACAGAGACAATCTGA
TCCTCAGCCCGTTTATTCGTCTGCTTCCATTCCCGCTAATGCCACTTTTTCTGATAGCTCTGCCCGCGACCAAACACAGT
CGGCTAATGAGGCGATAGAAGTGAGTCGCGAAGATATCGAAGCGGCGCTAAAACAGCACCATGGCGTGATTGCTCGGGTC
GCCAAAGCGCTTGGGCTCAGTCGTCAGGCGCTGTATCGGCGCATGGATAAGTTTGGTTTAGATAAGTCATAG

Upstream 100 bases:

>100_bases
GTACGATAAAAGCCCAATAAAAGTGCGATAACAATAGGATGTTATTGCACTTTTTGTTACTTTACGGTTAATAGTTTTAT
ATAGGACAACACTCATACTT

Downstream 100 bases:

>100_bases
GCTAAGCGCAGATGCTAGTTCGTAGCTTTTAGACAACAGCTTCTAGGCAACAGCTACTAGGGCATAGATACTAAGTCTCA
GATACTAGGCTACAGATTCT

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MDTILIVDDNHAICQALGLMLELNDYRVLTCHSPEDALGLLATQDVDLVIQDMNFTRDTTSGEEGKQLFYALRERQGDLP
IILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITNLIALYKLSRANHRLERVNHQRQVAFADADLCGIVFGSGAM
QRCIDLALQLARSDVSVLITGPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQDIAEGRFREDLFYRLNVIELA
LSPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPGNVRELENACKRAVLLAKSHVLTEADFGLAPVVSAARSATS
YISAASEPRRLDQRQSDPRIFEQRQSDPQPVYSSASIPANATFSDSSARDQTQSANEAIEVSREDIEAALKQHHGVIARV
AKALGLSRQALYRRMDKFGLDKS

Sequences:

>Translated_503_residues
MDTILIVDDNHAICQALGLMLELNDYRVLTCHSPEDALGLLATQDVDLVIQDMNFTRDTTSGEEGKQLFYALRERQGDLP
IILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITNLIALYKLSRANHRLERVNHQRQVAFADADLCGIVFGSGAM
QRCIDLALQLARSDVSVLITGPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQDIAEGRFREDLFYRLNVIELA
LSPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPGNVRELENACKRAVLLAKSHVLTEADFGLAPVVSAARSATS
YISAASEPRRLDQRQSDPRIFEQRQSDPQPVYSSASIPANATFSDSSARDQTQSANEAIEVSREDIEAALKQHHGVIARV
AKALGLSRQALYRRMDKFGLDKS
>Mature_503_residues
MDTILIVDDNHAICQALGLMLELNDYRVLTCHSPEDALGLLATQDVDLVIQDMNFTRDTTSGEEGKQLFYALRERQGDLP
IILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITNLIALYKLSRANHRLERVNHQRQVAFADADLCGIVFGSGAM
QRCIDLALQLARSDVSVLITGPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQDIAEGRFREDLFYRLNVIELA
LSPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPGNVRELENACKRAVLLAKSHVLTEADFGLAPVVSAARSATS
YISAASEPRRLDQRQSDPRIFEQRQSDPQPVYSSASIPANATFSDSSARDQTQSANEAIEVSREDIEAALKQHHGVIARV
AKALGLSRQALYRRMDKFGLDKS

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=511, Percent_Identity=36.2035225048924, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1790299, Length=508, Percent_Identity=35.0393700787402, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI1790437, Length=503, Percent_Identity=35.1888667992048, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1788905, Length=389, Percent_Identity=40.3598971722365, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI87082117, Length=400, Percent_Identity=37.25, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1789087, Length=404, Percent_Identity=36.8811881188119, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1786524, Length=288, Percent_Identity=41.3194444444444, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87082152, Length=365, Percent_Identity=37.5342465753425, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789233, Length=377, Percent_Identity=35.0132625994695, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI87081872, Length=214, Percent_Identity=46.7289719626168, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787583, Length=287, Percent_Identity=37.6306620209059, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789828, Length=273, Percent_Identity=33.6996336996337, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081858, Length=348, Percent_Identity=28.448275862069, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55154; Mature: 55154

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTILIVDDNHAICQALGLMLELNDYRVLTCHSPEDALGLLATQDVDLVIQDMNFTRDTT
CCEEEEEECCHHHHHHHHHHEEECCEEEEEECCCCHHHHHHEECCCEEEEECCCCCCCCC
SGEEGKQLFYALRERQGDLPIILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITN
CCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHH
LIALYKLSRANHRLERVNHQRQVAFADADLCGIVFGSGAMQRCIDLALQLARSDVSVLIT
HHHHHHHHHHHHHHHHHCCHHHEEEECCCHHHHEECCHHHHHHHHHHHHHHCCCCEEEEE
GPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
CCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHCC
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQD
EECCCCCEEEHHHHCCCCCCCCHHHHHHHHCCCHHHHCCCCCEEEEEEEEECCCHHHHHH
IAEGRFREDLFYRLNVIELALSPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPG
HHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
NVRELENACKRAVLLAKSHVLTEADFGLAPVVSAARSATSYISAASEPRRLDQRQSDPRI
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHH
FEQRQSDPQPVYSSASIPANATFSDSSARDQTQSANEAIEVSREDIEAALKQHHGVIARV
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AKALGLSRQALYRRMDKFGLDKS
HHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDTILIVDDNHAICQALGLMLELNDYRVLTCHSPEDALGLLATQDVDLVIQDMNFTRDTT
CCEEEEEECCHHHHHHHHHHEEECCEEEEEECCCCHHHHHHEECCCEEEEECCCCCCCCC
SGEEGKQLFYALRERQGDLPIILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITN
CCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHH
LIALYKLSRANHRLERVNHQRQVAFADADLCGIVFGSGAMQRCIDLALQLARSDVSVLIT
HHHHHHHHHHHHHHHHHCCHHHEEEECCCHHHHEECCHHHHHHHHHHHHHHCCCCEEEEE
GPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
CCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHCC
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQD
EECCCCCEEEHHHHCCCCCCCCHHHHHHHHCCCHHHHCCCCCEEEEEEEEECCCHHHHHH
IAEGRFREDLFYRLNVIELALSPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPG
HHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
NVRELENACKRAVLLAKSHVLTEADFGLAPVVSAARSATSYISAASEPRRLDQRQSDPRI
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHH
FEQRQSDPQPVYSSASIPANATFSDSSARDQTQSANEAIEVSREDIEAALKQHHGVIARV
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AKALGLSRQALYRRMDKFGLDKS
HHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]