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The map label for this gene is cvrA [H]

Identifier: 160874064

GI number: 160874064

Start: 1116948

End: 1118678

Strand: Direct

Name: cvrA [H]

Synonym: Sbal195_0944

Alternate gene names: 160874064

Gene position: 1116948-1118678 (Clockwise)

Preceding gene: 160874062

Following gene: 160874066

Centisome position: 20.89

GC content: 49.28

Gene sequence:

>1731_bases
GTGGATGCAAATTCCATCAATAGTTTTTTTCTGATTGGCGCCTTGCTAACTGCAGTGAGTGTTTTACTCAGTCCCATGTC
TTCCCGTTTGGGTATCCCGATTCTTTTGATCTTCCTCGCCGTGGGTATTTTGGCCGGTGAAGATGGCCCTGGCGGAATAT
TGTTTGATGATTATTCCACCGCTTATTTAGTCAGTAACTTAGCGCTTGCTATCATCTTACTCGATGGTGGTATGCGTACC
CGTGTCGCCAGTTTTAGGGTGGCACTGTGGCCTGCATTATCGCTAGCGACCTTTGGCGTCGCTATCACAACCAGTATCAC
TGGCATGATGGCCGCATGGCTGTTTGACTTGCATTGGTTGCAAGGTTTGCTGGTGGGCGCGATTGTGGGCTCGACCGATG
CCGCCGCGGTATTCTCCTTATTGAAAGGGCGCAGTCTCAACGAGCGGGTTGGGGCAACCTTAGAAATCGAGTCCGGTAGT
AACGACCCTATGGCGGTGTTTTTAACCGTGACGCTGATTGCGATTCTCGCCAATGTGGACACTGAGATGTCCTTCAGCTT
TATGTTTATCAGCTTTATTAAGCAATTTGGTCTGGGTATATGCTTAGGTTTAGGCGGCGGCTGGATGCTGTGGAAGCTGG
TTAATTTGAGCAAATTAGCCGACGGCCTGTACTCTATTTTAGTCTTAAGCGGTGGTCTGATTATTTATGCTGCGTCTAAC
AAACTCGGCGGCAGTGGCATTTTATCGATTTACTTAGTCGGGCTTTTCCTCGGCAATAAGCCGACCCGTGGTCGCCATGC
GATTTTAAACGTACTGGATGGCATGACTTGGGTCAGCCAAATCGGTATGTTCTTGGTATTAGGGTTATTGCTTACCCCTT
CAGATTTAGTCGATATCCTGATCCCAGGTTTTGCACTGGCATTTGGGATGATTCTATTCGCTCGTCCTGTCGCTGTGTGG
ATCAGCCTATTGCCCTTTAAGAGCTTCAGCAGTCGCGACCGCTGGTTTATTTCGTGGGTAGGACTACGCGGCGCAGTGCC
TATCATCTTGGCGGTGTTCCCTATGATGGCGGGCTTACCGGGTGCTCAGTTGTACTTCAACTTAGCCTTCTTCGTCGTAT
TAGTATCGTTACTGGTTCAAGGTGCGTCTTTGACCACTGCGGCGCGTTTAGCTAAGGTGGAACTGCCCCCAAAGCCGTTG
CCCGTTTCGCGTTCGGGAGTTGAAATTTACCCGAGCAGTGAATGGGAAGTGTTTGTCTATCGTTTGAGTGAAAGTAAGTG
GTGCATTGGTGAACCGCTAAAACGCTTAGCTATGCCAGATGGAACACGGATTGCGGCGGTATTTAGGGATGACACTTTAC
TGCATCCGTCGGGCAGTACTCGCCTCGAAGCGGGAGATATACTCTGTGTGCTGGGTCAGGAGAAAAGTTTAGAAGCCTTG
AGTAATCTCTTTAGCCAAGCGCCAGAAAATAAAGAAGTGCAACGCTTCTTCGGTGATTTCTTTATTGAAACAGACGTTAA
GCTTGCGGATCTCGCACCAATTTATGGCTTGAGCTTAGATAATCTCGCCGATGATATGACAGTCGCCGATCTGGTAGTGT
TACAGCTTGGCGCTAATCCTGTGCTGGGCGATCAGTTCCAATGGCAATCGCTGCATTGGGTGGTGGCGGGGCTGTATGAA
GGCAAAGTTACTAACGTCGGTATTCGTTTACCGACCGAGCATTCGCTGTAA

Upstream 100 bases:

>100_bases
TTTTGTGCTAATATAAAATCATAAAATTGTAAGTTGAGTCATTTTTAACCTCGGTGATTTGTCTATCGTTTAACTAAACA
ACCTGTATAAGGAGGCGTTT

Downstream 100 bases:

>100_bases
TCTCATGCGCTAGATGCTTCTTGCCATAGAGAGTTGAAGTTGAAAGTTGTCATCGACAATTGCCATTGAAAGTTATCATC
GACAATTGTAATCGAAAGTC

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRT
RVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGS
NDPMAVFLTVTLIAILANVDTEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDILIPGFALAFGMILFARPVAVW
ISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPL
PVSRSGVEIYPSSEWEVFVYRLSESKWCIGEPLKRLAMPDGTRIAAVFRDDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVLQLGANPVLGDQFQWQSLHWVVAGLYE
GKVTNVGIRLPTEHSL

Sequences:

>Translated_576_residues
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRT
RVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGS
NDPMAVFLTVTLIAILANVDTEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDILIPGFALAFGMILFARPVAVW
ISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPL
PVSRSGVEIYPSSEWEVFVYRLSESKWCIGEPLKRLAMPDGTRIAAVFRDDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVLQLGANPVLGDQFQWQSLHWVVAGLYE
GKVTNVGIRLPTEHSL
>Mature_576_residues
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRT
RVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGS
NDPMAVFLTVTLIAILANVDTEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDILIPGFALAFGMILFARPVAVW
ISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPL
PVSRSGVEIYPSSEWEVFVYRLSESKWCIGEPLKRLAMPDGTRIAAVFRDDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVLQLGANPVLGDQFQWQSLHWVVAGLYE
GKVTNVGIRLPTEHSL

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=577, Percent_Identity=59.6187175043327, Blast_Score=612, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 61985; Mature: 61985

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEECCCCH
AYLVSNLALAIILLDGGMRTRVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWL
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGSNDPMAVFLTVTLIAILANVD
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
TEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
CCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDIL
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IPGFALAFGMILFARPVAVWISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
GAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPLPVSRSGVEIYPSSEWEVFVY
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCEEEEE
RLSESKWCIGEPLKRLAMPDGTRIAAVFRDDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
EECCCCCCHHHHHHHHCCCCCCEEEEEEECCEEECCCCCCEEECCCEEEEECCCCCHHHH
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVLQLGANP
HHHHHCCCCCHHHHHHHHHHHEECCCCHHHCCCHHCCCHHHHHCHHHHHHHHHHHCCCCC
VLGDQFQWQSLHWVVAGLYEGKVTNVGIRLPTEHSL
CCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEECCCCH
AYLVSNLALAIILLDGGMRTRVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWL
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGSNDPMAVFLTVTLIAILANVD
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
TEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
CCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDIL
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IPGFALAFGMILFARPVAVWISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
GAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPLPVSRSGVEIYPSSEWEVFVY
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCEEEEE
RLSESKWCIGEPLKRLAMPDGTRIAAVFRDDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
EECCCCCCHHHHHHHHCCCCCCEEEEEEECCEEECCCCCCEEECCCEEEEECCCCCHHHH
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVLQLGANP
HHHHHCCCCCHHHHHHHHHHHEECCCCHHHCCCHHCCCHHHHHCHHHHHHHHHHHCCCCC
VLGDQFQWQSLHWVVAGLYEGKVTNVGIRLPTEHSL
CCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA