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The map label for this gene is dipZ [H]

Identifier: 160873785

GI number: 160873785

Start: 807801

End: 809660

Strand: Reverse

Name: dipZ [H]

Synonym: Sbal195_0663

Alternate gene names: 160873785

Gene position: 809660-807801 (Counterclockwise)

Preceding gene: 160873786

Following gene: 160873784

Centisome position: 15.14

GC content: 49.41

Gene sequence:

>1860_bases
ATGAAAAAACTACTCAGCCTTATTTTCACGTCTTTATTGCTCCTCACGCCCTTAGCGCACAGTGAAGGGGTTTTCGGTAA
CAAATTCGACTTCATGAAGAGTGAGCCGGAATTGATGCCTGTCGATCAAGCCTTTGCCTTCGATTTCAAGCAAGAAGGTA
ATCAGGTCAAACTCAATTGGGTGATTGCCGACGGTTACTACATGTACCGCGACAAGCTTAAATTCAGTGTCAATGGCGCC
GAGCTAGGCACAGTGGCGCTGCCCAAGGGCAAGCCCCATCAAGATGAGTATTTTGGCGAGCAAGAAGTCTATTACACCTA
TGTGGATATTCCAGTTGCGCTGAAACAGGCCGATGAAAATGCCACGCTTACCGTCACTTTTATGGGCTGCGCCGAAGGTA
AGTTATGTTATCCACCAACCAAACGTGATGTAGTGCTAAAAGCGATTGCCGCCAACGATGGCTTAATCGCAGGTGCCGAA
GCGGGCGAATCAACCGTCGCAGCAGAACCAGCCAGCACTGAGTCTGCCAGCATTGAACCGAGCACGGCCGATAAAGCCAA
TCCCCAACCTATTACCCAGCAAGATACCCTGAGCCAAATGCTGTCAAACGACAGCCTAATTTGGACCTTAGTGATCTTCT
TTGGTCTGGGTGTCGGTCTGGCATTAACGCCTTGCGTGTTCCCTATGTACCCGATTTTGTCCGGTATTATTGTTGGCCAA
GGGCAAAAACTCTCAACCGCGAAAGCCTTTACCTTGTCTATGGCCTACGTCCAAGGCATGGCAATCACTTACTCTATCTT
AGGTTTAGTGGTCGCATCGGCAGGACTGAAATACCAAGCGGCATTGCAACATCCGGCCGTGTTAGTGGTTCTGGCGATTC
TGTTCTTTGTGCTCAGCTTATCTATGTTTGGCCTGTACGATTTAAAACTGCCATCGAGCTGGCAGGAGAAGATGAACTCA
GTATCGAACAACCAAAAAGGCGGCAACTTAGTTGGCGTATTCTTGATGGGCGTGATTTCAGGTCTGGTCGCATCACCTTG
CACTACCGCGCCGCTATCGGGTGCGCTCGTTTATGTGGCGCAAACCGGCGACTTACTCCAAGGCTTCTTAGCCCTGTATG
TGCTGAGTATGGGCATGGGTTTACCTCTGCTGATTATCGGCACCTCTGGCGGTAAATTATTACCCAGAGCAGGCGCTTGG
ATGGACATCATCAAAACCGTCTTCGGCTTCCTGTTGATCGCTGTGTCTATCGTAATGCTCGGTCGCATTTGGACGGGCGT
GGTATCCGATGTGCTCTGGTCACTGTGGGGCGTGAGCTTCACTGGCTACTTGATGCATCAGAACAAACTCAGTCCCTTCA
ACTGGAAACAAACTGTCCGTTCAGTGCTATTAACGCTGACGCTACTGGCAAGTTTCTCCTACGGATTCCAAGCTGTGATG
GGCCACTTTGGTTTTAATCACAATCCCGTAGGCACTGCGGCGACGACCGAAGAAGCCCATGGCTTTAAACGGATTAAATC
CATTAAAGATCTTGAGCAAGAAATCGCCGCCGCTGCCGCCCAAGGTAAGCCTGTGATGCTGGATCTCTACGCCGATTGGT
GTGTTGCCTGTAAAGAGTTCGAAGCCATCACCTTTAAGGATGCCGACGTGTTAGCCCGCATGAATAAAATCGTGCTGCTA
CAAGCCGATGTGACTAAGAGTGACAAGGTCGATGTGGCCTTACTCGAAAAATACAATGTGCTCGGTTTGCCTACCTTGTT
GATGTTTAACGAACAAGGTGATCAAAGGGAAGATTTACGTGTGACTGGTTTTATGGGCCCTAAAGATTTTGCCGCCCATT
TAGATCATCTGGTGAAATAG

Upstream 100 bases:

>100_bases
TGCTTAGACTCCACCCTTATCAAGTACCCGAAATTATTGCCGTGCCTGTGACTCACGGGCTACCAGCCTACTTAGATTGG
ATAAAAGACAACACTCAGCC

Downstream 100 bases:

>100_bases
TCACTATTTAGACTTAGACCACTAAAGCGATTTCACTCTCGCCGGTTTTAACCAGCAAGTGTATTTGCCGCAACACCAAT
AGAAAGCGGACTTTTTTCAT

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNWVIADGYYMYRDKLKFSVNGA
ELGTVALPKGKPHQDEYFGEQEVYYTYVDIPVALKQADENATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAE
AGESTVAAEPASTESASIEPSTADKANPQPITQQDTLSQMLSNDSLIWTLVIFFGLGVGLALTPCVFPMYPILSGIIVGQ
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSLSMFGLYDLKLPSSWQEKMNS
VSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAW
MDIIKTVFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLEQEIAAAAAQGKPVMLDLYADWCVACKEFEAITFKDADVLARMNKIVLL
QADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGDQREDLRVTGFMGPKDFAAHLDHLVK

Sequences:

>Translated_619_residues
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNWVIADGYYMYRDKLKFSVNGA
ELGTVALPKGKPHQDEYFGEQEVYYTYVDIPVALKQADENATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAE
AGESTVAAEPASTESASIEPSTADKANPQPITQQDTLSQMLSNDSLIWTLVIFFGLGVGLALTPCVFPMYPILSGIIVGQ
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSLSMFGLYDLKLPSSWQEKMNS
VSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAW
MDIIKTVFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLEQEIAAAAAQGKPVMLDLYADWCVACKEFEAITFKDADVLARMNKIVLL
QADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGDQREDLRVTGFMGPKDFAAHLDHLVK
>Mature_619_residues
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNWVIADGYYMYRDKLKFSVNGA
ELGTVALPKGKPHQDEYFGEQEVYYTYVDIPVALKQADENATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAE
AGESTVAAEPASTESASIEPSTADKANPQPITQQDTLSQMLSNDSLIWTLVIFFGLGVGLALTPCVFPMYPILSGIIVGQ
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSLSMFGLYDLKLPSSWQEKMNS
VSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAW
MDIIKTVFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLEQEIAAAAAQGKPVMLDLYADWCVACKEFEAITFKDADVLARMNKIVLL
QADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGDQREDLRVTGFMGPKDFAAHLDHLVK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=609, Percent_Identity=44.8275862068966, Blast_Score=506, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 67125; Mature: 67125

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNW
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEE
VIADGYYMYRDKLKFSVNGAELGTVALPKGKPHQDEYFGEQEVYYTYVDIPVALKQADEN
EEECCEEEEEEEEEEEECCCCCCEEECCCCCCCCHHHCCCCEEEEEEEECEEEEEECCCC
ATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAEAGESTVAAEPASTESASIEP
CEEEEEEEECCCCCEECCCCCCCCEEEEEECCCCEEEECCCCCCCEECCCCCCCCCCCCC
STADKANPQPITQQDTLSQMLSNDSLIWTLVIFFGLGVGLALTPCVFPMYPILSGIIVGQ
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECC
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHH
SMFGLYDLKLPSSWQEKMNSVSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVA
HHHCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
QTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAWMDIIKTVFGFLLIAVSIVML
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLEQEIAAAAAQGKPVMLDLYADWCVACKEF
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHC
EAITFKDADVLARMNKIVLLQADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGDQREDLR
CEEEECCHHHHHHCCEEEEEEECCCCCCCCCEEEHHCCCCCCCCEEEEECCCCCCCCCEE
VTGFMGPKDFAAHLDHLVK
EEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNW
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEE
VIADGYYMYRDKLKFSVNGAELGTVALPKGKPHQDEYFGEQEVYYTYVDIPVALKQADEN
EEECCEEEEEEEEEEEECCCCCCEEECCCCCCCCHHHCCCCEEEEEEEECEEEEEECCCC
ATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAEAGESTVAAEPASTESASIEP
CEEEEEEEECCCCCEECCCCCCCCEEEEEECCCCEEEECCCCCCCEECCCCCCCCCCCCC
STADKANPQPITQQDTLSQMLSNDSLIWTLVIFFGLGVGLALTPCVFPMYPILSGIIVGQ
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECC
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHH
SMFGLYDLKLPSSWQEKMNSVSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVA
HHHCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
QTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAWMDIIKTVFGFLLIAVSIVML
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLEQEIAAAAAQGKPVMLDLYADWCVACKEF
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHC
EAITFKDADVLARMNKIVLLQADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGDQREDLR
CEEEECCHHHHHHCCEEEEEEECCCCCCCCCEEEHHCCCCCCCCEEEEECCCCCCCCCEE
VTGFMGPKDFAAHLDHLVK
EEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA