Click here to switch to the map view.

The map label for this gene is kefC [H]

Identifier: 160873784

GI number: 160873784

Start: 805964

End: 807619

Strand: Reverse

Name: kefC [H]

Synonym: Sbal195_0662

Alternate gene names: 160873784

Gene position: 807619-805964 (Counterclockwise)

Preceding gene: 160873785

Following gene: 160873783

Centisome position: 15.1

GC content: 49.15

Gene sequence:

>1656_bases
ATGGAACCCGGTATCCTCATTATCACACTCATCTGCGGCATGCTCGTCAGCCGTATAGGACTGCCACCGCTCATCGGCTA
CTTAGTGGCAGGCTTTGTACTATTCGTCCTCGGGATAGATAAAGAAAGCCTGCCATTGCTGCAAGAACTCGCCAGCCTAG
GCGTGACTTTGCTGCTGTTTGCTATTGGTTTAAAACTCGATATTCGCAGCCTGTTCAAGGCCGAAGTGTGGGCGGGTTCG
AGTGTCCACTTAGTTCTCTCAATTGTCGTTTTTGTGCCGATTCTGAAACTCTTTGGCTTACTGGGTTTAAGCCAACTCAC
GAGTCTTAACCTTGAGCAACTGACGTTAATCGCCTTCGCGTTAAGCTTCTCCAGTACAGTATTTGCGGTCAAAGTGTTAG
AAGATAAGGGCGATGTCCAATCCCTCTACGGCCGGGTCGCCATTGGTATCTTGATTATGCAGGATATCTTCGCCGTACTG
TTTTTAACGATTTCTAAGGGCGATGTACCTTCGGTATGGGCCTTCGCATTACTCTTACTACCACTGGCTAAGCCGCTAAT
TTATAAAGCCTTCGACCGTGTCGGCCACGGTGAACTCTTAGTGCTCTTCGGCCTAGTTATGGCACTCGTGGTTGGCGCTT
GGTTATTTGAATCTGTTGGCCTGAAACCCGATCTCGGCGCACTGATCATAGGTATCTTGTTGGCGGGCCACAAAAAGTCC
TCAGAGCTGGCAAAATCCCTATTCTATTTTAAAGAACTCTTCCTCGTGGCCTTCTTCTTAACGATTGGTCTCAACGGTTT
ACCTACGGTATCGGATATCGTACTCGCGGCGCTGTTAGTGCTGTTAGTGCCGCTTAAAATCCTGCTGTTTGTTTACATTC
TTACCCGCTTTAAGCTGCGTTCACGTACCTCTATGTTGGGCTCGTTCAACCTAGGTAACTTCAGTGAATTCGGTTTAATT
GTCGCCGCCGTCGCCACCTATAAAGGTTGGTTGCCTCCCGAGTGGCTAGTGATCATCGCCGTGGCATTAAGCTTTAGCTT
TTTACTCGCCGCGCCGCTTAACGCTACCGTCGGTAACATCTATCAACGATTCCAGCAGCGTTTAATCAAGCTTGAAAAAA
GCCCGTTACACCCAGAAGACAGACCGATCGCCATTGGCAATCCACGCTTCTTAATCTTAGGCATGGGCCGCATTGGTAGC
GGCGCCTACGATGAACTCAGGGAACAATTTGACGGCGAAATTCTCGGCATTGAGCACAAGCAAGACTTAGTCGATTTACA
TAAAGCCAAGGGCCGCAACGTAGTGCAAGGTGACGCCGCGGATACCGACTTTTGGGAGAAACTCGACAGAGCGCCTAACC
TTGAATTAGTGCTGCTGGCCATGCCGCACCACGCGGGAAATATGTTTGCGGTTGAGCAACTTAAGAAACTGAATTACCAA
GGCAAGATCAGTGCAATTGTGCAGTACAGTGACGATGCCGCGGCACTTCGCGAATCGGGCGTACACAGTGTTTACAACCT
GTACGAAGCTGCGGGTGCCGGTTTTGTGGATCATGTGATTTATGAGCTGTTGCAAGACTCGGAGAAAAACGCAGCTCAAG
CGGAAGAAACAGCGCAAGTGGCTGATCCTAAAATTAATGCAGAGTCCAATAGTTAA

Upstream 100 bases:

>100_bases
GAAAGCGGACTTTTTTCATTAAAAGTCCGCTTTTTTGTTCCAGTGTCATAGATTTCTTATACAATCACTCATAATTTTGG
ACTTTTTAGATTGGAGCATC

Downstream 100 bases:

>100_bases
GTGCCTGCTAATGCTGCATTGAATTAAAATCACGCCATAATAGGCCGCACAAACGAGCAGTAACTTCCTCTGCAAGTTTG
TGCGGCCTCCAACTAACTAC

Product: sodium/hydrogen exchanger

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MEPGILIITLICGMLVSRIGLPPLIGYLVAGFVLFVLGIDKESLPLLQELASLGVTLLLFAIGLKLDIRSLFKAEVWAGS
SVHLVLSIVVFVPILKLFGLLGLSQLTSLNLEQLTLIAFALSFSSTVFAVKVLEDKGDVQSLYGRVAIGILIMQDIFAVL
FLTISKGDVPSVWAFALLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVVGAWLFESVGLKPDLGALIIGILLAGHKKS
SELAKSLFYFKELFLVAFFLTIGLNGLPTVSDIVLAALLVLLVPLKILLFVYILTRFKLRSRTSMLGSFNLGNFSEFGLI
VAAVATYKGWLPPEWLVIIAVALSFSFLLAAPLNATVGNIYQRFQQRLIKLEKSPLHPEDRPIAIGNPRFLILGMGRIGS
GAYDELREQFDGEILGIEHKQDLVDLHKAKGRNVVQGDAADTDFWEKLDRAPNLELVLLAMPHHAGNMFAVEQLKKLNYQ
GKISAIVQYSDDAAALRESGVHSVYNLYEAAGAGFVDHVIYELLQDSEKNAAQAEETAQVADPKINAESNS

Sequences:

>Translated_551_residues
MEPGILIITLICGMLVSRIGLPPLIGYLVAGFVLFVLGIDKESLPLLQELASLGVTLLLFAIGLKLDIRSLFKAEVWAGS
SVHLVLSIVVFVPILKLFGLLGLSQLTSLNLEQLTLIAFALSFSSTVFAVKVLEDKGDVQSLYGRVAIGILIMQDIFAVL
FLTISKGDVPSVWAFALLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVVGAWLFESVGLKPDLGALIIGILLAGHKKS
SELAKSLFYFKELFLVAFFLTIGLNGLPTVSDIVLAALLVLLVPLKILLFVYILTRFKLRSRTSMLGSFNLGNFSEFGLI
VAAVATYKGWLPPEWLVIIAVALSFSFLLAAPLNATVGNIYQRFQQRLIKLEKSPLHPEDRPIAIGNPRFLILGMGRIGS
GAYDELREQFDGEILGIEHKQDLVDLHKAKGRNVVQGDAADTDFWEKLDRAPNLELVLLAMPHHAGNMFAVEQLKKLNYQ
GKISAIVQYSDDAAALRESGVHSVYNLYEAAGAGFVDHVIYELLQDSEKNAAQAEETAQVADPKINAESNS
>Mature_551_residues
MEPGILIITLICGMLVSRIGLPPLIGYLVAGFVLFVLGIDKESLPLLQELASLGVTLLLFAIGLKLDIRSLFKAEVWAGS
SVHLVLSIVVFVPILKLFGLLGLSQLTSLNLEQLTLIAFALSFSSTVFAVKVLEDKGDVQSLYGRVAIGILIMQDIFAVL
FLTISKGDVPSVWAFALLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVVGAWLFESVGLKPDLGALIIGILLAGHKKS
SELAKSLFYFKELFLVAFFLTIGLNGLPTVSDIVLAALLVLLVPLKILLFVYILTRFKLRSRTSMLGSFNLGNFSEFGLI
VAAVATYKGWLPPEWLVIIAVALSFSFLLAAPLNATVGNIYQRFQQRLIKLEKSPLHPEDRPIAIGNPRFLILGMGRIGS
GAYDELREQFDGEILGIEHKQDLVDLHKAKGRNVVQGDAADTDFWEKLDRAPNLELVLLAMPHHAGNMFAVEQLKKLNYQ
GKISAIVQYSDDAAALRESGVHSVYNLYEAAGAGFVDHVIYELLQDSEKNAAQAEETAQVADPKINAESNS

Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=378, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1786232, Length=525, Percent_Identity=28, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786685, Length=536, Percent_Identity=26.3059701492537, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789749, Length=455, Percent_Identity=24.8351648351648, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 60089; Mature: 60089

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPGILIITLICGMLVSRIGLPPLIGYLVAGFVLFVLGIDKESLPLLQELASLGVTLLLF
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AIGLKLDIRSLFKAEVWAGSSVHLVLSIVVFVPILKLFGLLGLSQLTSLNLEQLTLIAFA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LSFSSTVFAVKVLEDKGDVQSLYGRVAIGILIMQDIFAVLFLTISKGDVPSVWAFALLLL
HHHCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
PLAKPLIYKAFDRVGHGELLVLFGLVMALVVGAWLFESVGLKPDLGALIIGILLAGHKKS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCH
SELAKSLFYFKELFLVAFFLTIGLNGLPTVSDIVLAALLVLLVPLKILLFVYILTRFKLR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRTSMLGSFNLGNFSEFGLIVAAVATYKGWLPPEWLVIIAVALSFSFLLAAPLNATVGNI
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YQRFQQRLIKLEKSPLHPEDRPIAIGNPRFLILGMGRIGSGAYDELREQFDGEILGIEHK
HHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHCCCEEECCCH
QDLVDLHKAKGRNVVQGDAADTDFWEKLDRAPNLELVLLAMPHHAGNMFAVEQLKKLNYQ
HHHHHHHHHCCCCEEECCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCC
GKISAIVQYSDDAAALRESGVHSVYNLYEAAGAGFVDHVIYELLQDSEKNAAQAEETAQV
CCEEEEEEECCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
ADPKINAESNS
CCCCCCCCCCC
>Mature Secondary Structure
MEPGILIITLICGMLVSRIGLPPLIGYLVAGFVLFVLGIDKESLPLLQELASLGVTLLLF
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AIGLKLDIRSLFKAEVWAGSSVHLVLSIVVFVPILKLFGLLGLSQLTSLNLEQLTLIAFA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LSFSSTVFAVKVLEDKGDVQSLYGRVAIGILIMQDIFAVLFLTISKGDVPSVWAFALLLL
HHHCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
PLAKPLIYKAFDRVGHGELLVLFGLVMALVVGAWLFESVGLKPDLGALIIGILLAGHKKS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCH
SELAKSLFYFKELFLVAFFLTIGLNGLPTVSDIVLAALLVLLVPLKILLFVYILTRFKLR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRTSMLGSFNLGNFSEFGLIVAAVATYKGWLPPEWLVIIAVALSFSFLLAAPLNATVGNI
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YQRFQQRLIKLEKSPLHPEDRPIAIGNPRFLILGMGRIGSGAYDELREQFDGEILGIEHK
HHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHCCCEEECCCH
QDLVDLHKAKGRNVVQGDAADTDFWEKLDRAPNLELVLLAMPHHAGNMFAVEQLKKLNYQ
HHHHHHHHHCCCCEEECCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCC
GKISAIVQYSDDAAALRESGVHSVYNLYEAAGAGFVDHVIYELLQDSEKNAAQAEETAQV
CCEEEEEEECCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
ADPKINAESNS
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA