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The map label for this gene is dcuA [H]

Identifier: 160873766

GI number: 160873766

Start: 772817

End: 774064

Strand: Reverse

Name: dcuA [H]

Synonym: Sbal195_0644

Alternate gene names: 160873766

Gene position: 774064-772817 (Counterclockwise)

Preceding gene: 160873767

Following gene: 160873765

Centisome position: 14.48

GC content: 50.24

Gene sequence:

>1248_bases
ATGGGTAGCATGGGAGTCGGCTTTGCGGGCGGTGTCGGGGTACTGATACTGACCGCAGGGATGGGACTCAAACCGGGCAA
TATTCCGATTGATGTGATCCTCATCATTATGTCGGTTATCACCGCGATTGCGGCCATGCAAGTATCGGGAGGGATGGATT
ATTTAGTCTCACTGGCAGAAAAATTATTACGTAAGCATCCAAAACAAATCACTTTTCTGGCACCTGTAGTCACTTATTTC
ATGACACTCTTTGCAGGAACAGGCCACACCGCATTCTCAACCTTACCTGTTATTGCCGAAGTCGCAAAAGAGCAAGGTAT
TCGTCCCTCTCGTCCTCTTTCTATCGCCGTTGTCGCGTCCCAAGTCGCCATAACCGCTTCACCGATTTCGGCGGCAGTCG
TGTTCTTCTCAGGCATTCTAGAACCCTTTGGCGTGGACTATTTAGTACTGTTAGCCGTATGTATTCCTTCAACTTTCTTA
GCCTGTATGGTCGGCGCCGTTGTTGCTAACTTAATGGGTAAAGAGCTGGCTGATGATCCTATTTATCAAGACCGTTTAGC
TAAGGGCTTAGTCAAAACACGCGGTAAAACGGAGATCAAAATTAAAGCCGGCGCGAAACGCTCTGTGATGATTTTCTTAC
TGGCGATTGCGGCAGTGATGGCCTACGCCACTGCGATATCTGACAAAGTCGGCTTGATTGTTGACCCTGTACTACCACGC
GATGCTGCCATTATGGTGCTGATGCTCACGGCAGCTGCGGCTATCACGATTTTCTGTAAGTTAGACGCAAGTGAAATCTC
CAATGCGGCCACCTTTAAATCGGGCATGTCAGCCTGTGTCTGTGTGTTAGGTGTGGCTTGGTTAGGCGATACCTTAGTGT
CGAATCATATTGAGGAAATCAAAGATTTAGCAGGCACCTTACTGCAAAGTCAGCCTTGGTTATTGTCGGTCACCCTGTTC
TTTGCCTCCATGTTGCTCTACTCCCAAGGCGCAACCACTAAGGCGCTGATGCCTGCGGCCTTAGCCATTGGCGTGAGTCC
TTTAACTGCCGTTGCCTCTTTCGCCGCCGTCAGCGCGCTGTTTGTATTGCCCACTTATCCTACGCTACTGGCTGCGGTTG
AAATGGATGATACCGGCTCGACTCGGATTGGTAAGGCGGTATTTAACCATCCGTTCCTGGTCCCTGGCGTAGTGACGATT
GCCACCAGCGTGGCATTGGCCTTCCTGTTTGGCGGCATGATGCTGTAG

Upstream 100 bases:

>100_bases
AATATGCTCAGGCTATTGAAATTAAAAACAAAATAGAGTTAACACTATGATTATATTAGAGATAATTATCGTACTCGGGG
CCATTTACCTAGGTGCAAGG

Downstream 100 bases:

>100_bases
CGCAACTTTACCCAAAGTGTTCTAAGGGCTAATGCTAATAATTGGATTAACCCTCTTCTTTTAATCTGGATCTAAAGACT
TTGTGTTGGCGTGATGCAGG

Product: anaerobic c4-dicarboxylate antiporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MGSMGVGFAGGVGVLILTAGMGLKPGNIPIDVILIIMSVITAIAAMQVSGGMDYLVSLAEKLLRKHPKQITFLAPVVTYF
MTLFAGTGHTAFSTLPVIAEVAKEQGIRPSRPLSIAVVASQVAITASPISAAVVFFSGILEPFGVDYLVLLAVCIPSTFL
ACMVGAVVANLMGKELADDPIYQDRLAKGLVKTRGKTEIKIKAGAKRSVMIFLLAIAAVMAYATAISDKVGLIVDPVLPR
DAAIMVLMLTAAAAITIFCKLDASEISNAATFKSGMSACVCVLGVAWLGDTLVSNHIEEIKDLAGTLLQSQPWLLSVTLF
FASMLLYSQGATTKALMPAALAIGVSPLTAVASFAAVSALFVLPTYPTLLAAVEMDDTGSTRIGKAVFNHPFLVPGVVTI
ATSVALAFLFGGMML

Sequences:

>Translated_415_residues
MGSMGVGFAGGVGVLILTAGMGLKPGNIPIDVILIIMSVITAIAAMQVSGGMDYLVSLAEKLLRKHPKQITFLAPVVTYF
MTLFAGTGHTAFSTLPVIAEVAKEQGIRPSRPLSIAVVASQVAITASPISAAVVFFSGILEPFGVDYLVLLAVCIPSTFL
ACMVGAVVANLMGKELADDPIYQDRLAKGLVKTRGKTEIKIKAGAKRSVMIFLLAIAAVMAYATAISDKVGLIVDPVLPR
DAAIMVLMLTAAAAITIFCKLDASEISNAATFKSGMSACVCVLGVAWLGDTLVSNHIEEIKDLAGTLLQSQPWLLSVTLF
FASMLLYSQGATTKALMPAALAIGVSPLTAVASFAAVSALFVLPTYPTLLAAVEMDDTGSTRIGKAVFNHPFLVPGVVTI
ATSVALAFLFGGMML
>Mature_414_residues
GSMGVGFAGGVGVLILTAGMGLKPGNIPIDVILIIMSVITAIAAMQVSGGMDYLVSLAEKLLRKHPKQITFLAPVVTYFM
TLFAGTGHTAFSTLPVIAEVAKEQGIRPSRPLSIAVVASQVAITASPISAAVVFFSGILEPFGVDYLVLLAVCIPSTFLA
CMVGAVVANLMGKELADDPIYQDRLAKGLVKTRGKTEIKIKAGAKRSVMIFLLAIAAVMAYATAISDKVGLIVDPVLPRD
AAIMVLMLTAAAAITIFCKLDASEISNAATFKSGMSACVCVLGVAWLGDTLVSNHIEEIKDLAGTLLQSQPWLLSVTLFF
ASMLLYSQGATTKALMPAALAIGVSPLTAVASFAAVSALFVLPTYPTLLAAVEMDDTGSTRIGKAVFNHPFLVPGVVTIA
TSVALAFLFGGMML

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=403, Percent_Identity=61.5384615384615, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1790565, Length=402, Percent_Identity=36.5671641791045, Blast_Score=242, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 43088; Mature: 42957

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSMGVGFAGGVGVLILTAGMGLKPGNIPIDVILIIMSVITAIAAMQVSGGMDYLVSLAE
CCCCCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KLLRKHPKQITFLAPVVTYFMTLFAGTGHTAFSTLPVIAEVAKEQGIRPSRPLSIAVVAS
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHH
QVAITASPISAAVVFFSGILEPFGVDYLVLLAVCIPSTFLACMVGAVVANLMGKELADDP
HHHEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IYQDRLAKGLVKTRGKTEIKIKAGAKRSVMIFLLAIAAVMAYATAISDKVGLIVDPVLPR
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
DAAIMVLMLTAAAAITIFCKLDASEISNAATFKSGMSACVCVLGVAWLGDTLVSNHIEEI
HHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDLAGTLLQSQPWLLSVTLFFASMLLYSQGATTKALMPAALAIGVSPLTAVASFAAVSAL
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FVLPTYPTLLAAVEMDDTGSTRIGKAVFNHPFLVPGVVTIATSVALAFLFGGMML
HHHCCHHHHHEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSMGVGFAGGVGVLILTAGMGLKPGNIPIDVILIIMSVITAIAAMQVSGGMDYLVSLAE
CCCCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KLLRKHPKQITFLAPVVTYFMTLFAGTGHTAFSTLPVIAEVAKEQGIRPSRPLSIAVVAS
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHH
QVAITASPISAAVVFFSGILEPFGVDYLVLLAVCIPSTFLACMVGAVVANLMGKELADDP
HHHEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IYQDRLAKGLVKTRGKTEIKIKAGAKRSVMIFLLAIAAVMAYATAISDKVGLIVDPVLPR
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
DAAIMVLMLTAAAAITIFCKLDASEISNAATFKSGMSACVCVLGVAWLGDTLVSNHIEEI
HHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDLAGTLLQSQPWLLSVTLFFASMLLYSQGATTKALMPAALAIGVSPLTAVASFAAVSAL
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FVLPTYPTLLAAVEMDDTGSTRIGKAVFNHPFLVPGVVTIATSVALAFLFGGMML
HHHCCHHHHHEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11004174; 14500908; 8898907 [H]