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The map label for this gene is slyA [H]

Identifier: 160873686

GI number: 160873686

Start: 654485

End: 654958

Strand: Direct

Name: slyA [H]

Synonym: Sbal195_0564

Alternate gene names: 160873686

Gene position: 654485-654958 (Clockwise)

Preceding gene: 160873684

Following gene: 160873687

Centisome position: 12.24

GC content: 48.95

Gene sequence:

>474_bases
ATGCAAAAAGAATTAGAGCGATTGAAAGAGTTATCACTGGCGGAGCATTTAGGCCGTCTGCATCGATTGTGGCGTACCGT
GGCCGATGTCGAACTGGCGCCTTTGGGATTAACCCATCCCCGCTGGACGGCATTGTGGAAATTACTGCGTTTAGGCGACA
GCGTGAGCCAGAAAGTGTTGGCCGATGCCTTAGAAATTGAATTGGCTTCGCTAATGCGCACCTTAGGGCAATTAGAAGAG
CAAGGTTTAGTCGAGCGTCATTGCTGCGACAAAGATAAGCGCGCAAGGATTGTGACATTAACGCCTGCGGGATTGGATGT
ACTAAAGCAAATGGAAGCGCGGATTATTCAAGTCCGCCGTGAGTTATTAGCTGGGATCAGTGCCAGTGAACTCAGCGAAT
TTGAACGCATTATTAGCCTGATTAGTGACAACGCCAGCGCCAAATTGGCCAAGGCAACAGCAACTATTTTGTGA

Upstream 100 bases:

>100_bases
TTTTGCGCCATAGGACACAGAAAATTTTTTATATAAGCACATTTACTTAGCCTGCTAACTAAGTATAATGCTTAGCACGC
TAACTAAGTGGGTGAGCAAG

Downstream 100 bases:

>100_bases
GAAAGAAGATGACACCGGATCAACAGTTTGCCCGTTTAGTAAAATTTGCCATGTTCGCCTTTGTGATGGTTTTCGGCTAT
TTCATGCTGGCCGACACTAT

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVLADALEIELASLMRTLGQLEE
QGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRRELLAGISASELSEFERIISLISDNASAKLAKATATIL

Sequences:

>Translated_157_residues
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVLADALEIELASLMRTLGQLEE
QGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRRELLAGISASELSEFERIISLISDNASAKLAKATATIL
>Mature_157_residues
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVLADALEIELASLMRTLGQLEE
QGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRRELLAGISASELSEFERIISLISDNASAKLAKATATIL

Specific function: Transcription regulator that either activates or represses expression of target genes. Regulates the cpm operon, which contains the cpmA, cpmB, cpmC, cpmD, cpmE, cpmF, cpmG and cpmH, an operon involved in carbapenem-like antibiotic production [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=135, Percent_Identity=42.2222222222222, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17623; Mature: 17623

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
ADALEIELASLMRTLGQLEEQGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRR
HHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ELLAGISASELSEFERIISLISDNASAKLAKATATIL
HHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
ADALEIELASLMRTLGQLEEQGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRR
HHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ELLAGISASELSEFERIISLISDNASAKLAKATATIL
HHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12147472; 14528314 [H]