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The map label for this gene is dctS [H]

Identifier: 160873592

GI number: 160873592

Start: 536107

End: 537918

Strand: Direct

Name: dctS [H]

Synonym: Sbal195_0468

Alternate gene names: 160873592

Gene position: 536107-537918 (Clockwise)

Preceding gene: 160873579

Following gene: 160873595

Centisome position: 10.03

GC content: 50.94

Gene sequence:

>1812_bases
ATGGCGACGGGCTCTTGGTGTAAAGCGGTAGTGATGGGATTATGCCTAAGTGTCATTGGGCTCAATCAGTCCTATGCCGA
TGACGTGCCACAGGTGAACCACTTTAAAGTCGGAGTGTTGGCCAACCACGGCGTATTACAGGCCAAGCAGCGATGGCAAC
CTATGATGGATTACCTGACTGAACAAGTGCCCAATAGCCATTTTGAAGTGGTGCCCGTTGACTTTAATGGTATGCGTAGC
CAGTTACTCGGCCATGATTTGCAGTTTATCGTCACCAACCCCGGGCAATATCTGCATCTAAGCAATAACTTTCCGCTGTC
TTGGCTCGCGACGATGAAAAGCCGCAAGCATCAGGGCAGTACTTTTACCATAGGCGCGACTATTATTGTCCGCGCCGATA
GCCCTATCCGCACTCTGCAGGATTTGCGCGGGCGCAATGTGGTCGCCAGTGATCCGCAGGCATTAGGCGGGTATCAGGCG
GCCATGGGGTTACTGCATAAAATGGGCTTTTTACCCGAACAGTTTTTTGGGCAAGTGCGCTTCCTCGGTTTTCCATTGGA
GCCGCTTGTCTATCAAGTCCGTGACGGCAGCGCCGATGCCGCCATCGCGCCTTTTTGCACTTTAGAGGAAATGATCGCAA
CGGGTCTTGTTAATCAGGCCGATTATCGGGTGATCCACCCGACTAAACCGGCAGGATATGATTGTGAGGTGAGCACTCAG
TTATACCCCAACTGGTCATTCGCCGCGGCGGATACGGTTGCCCCTAAGCTGACGATGGCGATCACCCGCGCCTTATTTGA
TTTACCCGCCGACCATGTCGCTGCCATTACTGCCGATACTTTGGGCTGGACGGCGCCAGTCAGCCAGTTGAAAGTGATTG
AGTTATTTAAGGAATTACAGCTGCAAGGTGCGTCGCCGCCACTCTATCAAACTGTATACAAATGGATGGCGAAAAATAAA
GAGTGGGGCGGTGTGCTGCTATTAATCTTCATTATTTCGACTATTTATCACCTGTGGCTTGAATATAAGTTTCGCCAGAA
AAGCGAGTTCTTACTCAATACTGAGCGCCAATTAAAGGACAAGGCATTACAGCTTGAGCGGCTGCAAAGTGCGGCAATTC
TGGGGGAAATTGGCGCTGGCCTTGCCCATGAACTCAATCAACCCATAGCCGCCATTACCCAATACAGCGAAGGCGCCATG
CTGCAATTGGAAAGGCTTGGGCAAGATAATCCCGAACTTTATGATGTGCTTGGGAAAATTAATGCCCAGTCGATTCGCGC
GGGTGCGGTTGTGCACCGTATTCGCGGTTTACTCAAGCGGCGTCAGGCCAAGACTGAGCCTTTAGATATCGTGCTGGTGG
TGAAGGAGGCGTTAGCTTTACTGCGGCGCGAGTTAGATCGGGCCAATGTGCAAGTGAATGTGCGAGTGCAGGGGGAGCCC
TTTGAGCTGATGGGGGATAGCGTTGGCTTAAGTCAAATGTGGGTCAATCTTGTGAAAAATAGTTTAGATGCGCTAGAGGC
CTGCGGCGATAATCGGGTGCGGCAATTATGGATCGATATCTATTTTCAACCGCATGAAATCAAAGTATTAGTGATTGATA
ATGGCGAAGGGCTTCAGGGGCAGGCGAGTGACTTAATGGCATCTTTTGCCTCAACCAAAGATGCGGGATTGGGGCTTGGT
TTAGCTATCTGTAAGGATGTGGTCAGTCGCCACCATGGCAGCATTCAAATCGAAAACTGCCAGCAATCTACGCAAGCCTT
ATTGCCGTGGCAACAGGGTTGTGTGGTGACAGTCGTACTTCCCAAGGGATAG

Upstream 100 bases:

>100_bases
ATCTTAGGGCAGAAACCAGAGTTTGGCGGCATTTCACAGCTTGATTTTTATCTGCGAGTTAAAGTCGTTTAATAGCATAT
AAGACAGGGTAATAGCGGCG

Downstream 100 bases:

>100_bases
GGTTATACACTTATGAGTAACCCTTAATGTGCGCATTAGCGGAGCATCCGACAGCCTTTATTGGTTAGCGGTTAATATTA
ATAAAAGCATCATTTTCATA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MATGSWCKAVVMGLCLSVIGLNQSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLTEQVPNSHFEVVPVDFNGMRS
QLLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGSTFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQA
AMGLLHKMGFLPEQFFGQVRFLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTKPAGYDCEVSTQ
LYPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQLQGASPPLYQTVYKWMAKNK
EWGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKDKALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAM
LQLERLGQDNPELYDVLGKINAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEP
FELMGDSVGLSQMWVNLVKNSLDALEACGDNRVRQLWIDIYFQPHEIKVLVIDNGEGLQGQASDLMASFASTKDAGLGLG
LAICKDVVSRHHGSIQIENCQQSTQALLPWQQGCVVTVVLPKG

Sequences:

>Translated_603_residues
MATGSWCKAVVMGLCLSVIGLNQSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLTEQVPNSHFEVVPVDFNGMRS
QLLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGSTFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQA
AMGLLHKMGFLPEQFFGQVRFLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTKPAGYDCEVSTQ
LYPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQLQGASPPLYQTVYKWMAKNK
EWGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKDKALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAM
LQLERLGQDNPELYDVLGKINAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEP
FELMGDSVGLSQMWVNLVKNSLDALEACGDNRVRQLWIDIYFQPHEIKVLVIDNGEGLQGQASDLMASFASTKDAGLGLG
LAICKDVVSRHHGSIQIENCQQSTQALLPWQQGCVVTVVLPKG
>Mature_602_residues
ATGSWCKAVVMGLCLSVIGLNQSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLTEQVPNSHFEVVPVDFNGMRSQ
LLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGSTFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQAA
MGLLHKMGFLPEQFFGQVRFLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTKPAGYDCEVSTQL
YPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQLQGASPPLYQTVYKWMAKNKE
WGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKDKALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAML
QLERLGQDNPELYDVLGKINAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEPF
ELMGDSVGLSQMWVNLVKNSLDALEACGDNRVRQLWIDIYFQPHEIKVLVIDNGEGLQGQASDLMASFASTKDAGLGLGL
AICKDVVSRHHGSIQIENCQQSTQALLPWQQGCVVTVVLPKG

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=25.8964143426295, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790436, Length=266, Percent_Identity=23.6842105263158, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66753; Mature: 66622

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGSWCKAVVMGLCLSVIGLNQSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLT
CCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
EQVPNSHFEVVPVDFNGMRSQLLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGS
HHCCCCCEEEEEECCCHHHHHHCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCC
TFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQAAMGLLHKMGFLPEQFFGQVR
EEEEEEEEEEECCCCHHHHHHHCCCCCCCCCCHHHCHHHHHHHHHHHHCCCCHHHHCCEE
FLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTKPAGYDCEVSTQ
EECCCHHHHHEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCE
LYPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHCCCCCCHHHHHHHHHHHHHH
LQGASPPLYQTVYKWMAKNKEWGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKD
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
KALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAMLQLERLGQDNPELYDVLGKI
HHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCCCEEEHHHCCCCCHHHHHHHHCC
NAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCC
FELMGDSVGLSQMWVNLVKNSLDALEACGDNRVRQLWIDIYFQPHEIKVLVIDNGEGLQG
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEEEEECCCCCCC
QASDLMASFASTKDAGLGLGLAICKDVVSRHHGSIQIENCQQSTQALLPWQQGCVVTVVL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCCCCEEEEEE
PKG
CCC
>Mature Secondary Structure 
ATGSWCKAVVMGLCLSVIGLNQSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLT
CCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
EQVPNSHFEVVPVDFNGMRSQLLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGS
HHCCCCCEEEEEECCCHHHHHHCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCC
TFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQAAMGLLHKMGFLPEQFFGQVR
EEEEEEEEEEECCCCHHHHHHHCCCCCCCCCCHHHCHHHHHHHHHHHHCCCCHHHHCCEE
FLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTKPAGYDCEVSTQ
EECCCHHHHHEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCE
LYPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHCCCCCCHHHHHHHHHHHHHH
LQGASPPLYQTVYKWMAKNKEWGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKD
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
KALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAMLQLERLGQDNPELYDVLGKI
HHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCCCEEEHHHCCCCCHHHHHHHHCC
NAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCC
FELMGDSVGLSQMWVNLVKNSLDALEACGDNRVRQLWIDIYFQPHEIKVLVIDNGEGLQG
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEEEEECCCCCCC
QASDLMASFASTKDAGLGLGLAICKDVVSRHHGSIQIENCQQSTQALLPWQQGCVVTVVL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCCCCEEEEEE
PKG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]