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The map label for this gene is yqhD [H]

Identifier: 160873397

GI number: 160873397

Start: 309674

End: 310831

Strand: Reverse

Name: yqhD [H]

Synonym: Sbal195_0271

Alternate gene names: 160873397

Gene position: 310831-309674 (Counterclockwise)

Preceding gene: 160873398

Following gene: 160873396

Centisome position: 5.81

GC content: 49.57

Gene sequence:

>1158_bases
ATGCTAAATTTTAACTATTACAACCCAACCCGTATCCGTTTTGGTAAAGACACTATCGCCGAAATTGATGCTTTAGTACC
GAGCGATGCTAAAGTCATGATCCTATTTGGCGGCAGCAGCGCCAGAAAAACCGGCACGCTAGATGAAGTTAAACAATCAT
TGGGCAATCGTTTCGTCGTCGAGTTCGATGGTATTGAGCCAAACCCAACCTATGAAACCTTAATGAAAGCCGTCGCCCAA
GTGCGCGAACAGAAGATCGACTTCCTCCTCGCAGTGGGTGGTGGCTCTGTTATCGATGGCACTAAATTTGTTGCCGCTGC
TGCGGTATTCGAAGGCGAACCTTGGGACATTCTCACTAGTTGGGGCGCAAAAGTAACTCAAGCTATGTCTTTTGGCTCAG
TATTAACCTTGCCTGCGACAGGCTCAGAAATGAACAACGCCAGCGTAGTGACCCGTAAATCACTGCAAGCTAAGCTGCCA
TTCCGTAATGACTTGGTTTATCCACAATTCTCAATACTCGATCCGACGAAAACCTTCACCCTGCCAGAACGCCAAGTGGC
CAACGGTGTCGTCGATGCTTTTGTGCATATCACAGAGCAATACCTCACTTACCCCGTTAACGCCGCCGTACAGGACAGAT
TTGCCGAAGGTCTGTTACAAACCTTGATTGAGCTTGGTCCACAGGTACTGGTTCAACCCGAAGACTACGACATTCGCGCT
AACTTAATGTGGGTTGCCACTATGGCACTCAACGGCACGATTGGCGTAGGCGTTCCGCACGATTGGGCAACCCACATGAT
AGGCCATGAACTGACTGCGCTTTACGACATCGACCATGCGCGTACATTGGCAATCGTATTGCCTGCCCTGCTGCAATGTA
CCAAAGAGGCTAAGCGCGAAAAGTTACTCCAGTACGCAGACCGAGTGTGGCACATCAACACAGGTACCGATGACGAGCGC
ATCGATGCCGCTATTGCAAAAACTAAGGCTTTCTTCGAAGCCATGGGCATACCGACACATTTATCTGCCTATGATCTCGA
TGCCAGCCACGTTGATACCGTAGTGAAACAGCTTGAACTGCACGGCATGGTGGCACTCGGCGAACATGGCAACATTAACC
CAGCAATGAGCCGTGACATTTTGACCTTAGCCCTATAA

Upstream 100 bases:

>100_bases
ACGACTGGTCTACTAATTTAACGAGCGATTAATTAACGCAGCGCATTTAACACTGCTAATTTAAAGTAGCTCACTTAAAG
TAATAAGGGATAAATCATCC

Downstream 100 bases:

>100_bases
CGTCAAATGAACTAAACCCAAAGCTCACACGTATTGATGTGAGCAACTTAGGTAAAGGTATGAAAATGAATATATTAATG
GTACTAACTTCACACGATAA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MLNFNYYNPTRIRFGKDTIAEIDALVPSDAKVMILFGGSSARKTGTLDEVKQSLGNRFVVEFDGIEPNPTYETLMKAVAQ
VREQKIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTSWGAKVTQAMSFGSVLTLPATGSEMNNASVVTRKSLQAKLP
FRNDLVYPQFSILDPTKTFTLPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQTLIELGPQVLVQPEDYDIRA
NLMWVATMALNGTIGVGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLQCTKEAKREKLLQYADRVWHINTGTDDER
IDAAIAKTKAFFEAMGIPTHLSAYDLDASHVDTVVKQLELHGMVALGEHGNINPAMSRDILTLAL

Sequences:

>Translated_385_residues
MLNFNYYNPTRIRFGKDTIAEIDALVPSDAKVMILFGGSSARKTGTLDEVKQSLGNRFVVEFDGIEPNPTYETLMKAVAQ
VREQKIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTSWGAKVTQAMSFGSVLTLPATGSEMNNASVVTRKSLQAKLP
FRNDLVYPQFSILDPTKTFTLPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQTLIELGPQVLVQPEDYDIRA
NLMWVATMALNGTIGVGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLQCTKEAKREKLLQYADRVWHINTGTDDER
IDAAIAKTKAFFEAMGIPTHLSAYDLDASHVDTVVKQLELHGMVALGEHGNINPAMSRDILTLAL
>Mature_385_residues
MLNFNYYNPTRIRFGKDTIAEIDALVPSDAKVMILFGGSSARKTGTLDEVKQSLGNRFVVEFDGIEPNPTYETLMKAVAQ
VREQKIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTSWGAKVTQAMSFGSVLTLPATGSEMNNASVVTRKSLQAKLP
FRNDLVYPQFSILDPTKTFTLPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQTLIELGPQVLVQPEDYDIRA
NLMWVATMALNGTIGVGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLQCTKEAKREKLLQYADRVWHINTGTDDER
IDAAIAKTKAFFEAMGIPTHLSAYDLDASHVDTVVKQLELHGMVALGEHGNINPAMSRDILTLAL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=386, Percent_Identity=59.8445595854922, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI48994951, Length=320, Percent_Identity=24.375, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082107, Length=260, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789163, Length=287, Percent_Identity=25.7839721254355, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537053, Length=209, Percent_Identity=27.7511961722488, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321181, Length=309, Percent_Identity=25.2427184466019, Blast_Score=83, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42273; Mature: 42273

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFNYYNPTRIRFGKDTIAEIDALVPSDAKVMILFGGSSARKTGTLDEVKQSLGNRFVV
CCCCCCCCCCEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCEEEE
EFDGIEPNPTYETLMKAVAQVREQKIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTS
EECCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCEECCHHHHHHHHHCCCCCCHHHHH
WGAKVTQAMSFGSVLTLPATGSEMNNASVVTRKSLQAKLPFRNDLVYPQFSILDPTKTFT
HHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEHHHHEECCCCCCCCCCCEEECCCCCCCC
LPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQTLIELGPQVLVQPEDYDIRA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
NLMWVATMALNGTIGVGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLQCTKEAKRE
EEEEEEEEEECCEEECCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHH
KLLQYADRVWHINTGTDDERIDAAIAKTKAFFEAMGIPTHLSAYDLDASHVDTVVKQLEL
HHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHH
HGMVALGEHGNINPAMSRDILTLAL
CCEEEECCCCCCCHHHCCCEEEECC
>Mature Secondary Structure
MLNFNYYNPTRIRFGKDTIAEIDALVPSDAKVMILFGGSSARKTGTLDEVKQSLGNRFVV
CCCCCCCCCCEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCEEEE
EFDGIEPNPTYETLMKAVAQVREQKIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTS
EECCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCEECCHHHHHHHHHCCCCCCHHHHH
WGAKVTQAMSFGSVLTLPATGSEMNNASVVTRKSLQAKLPFRNDLVYPQFSILDPTKTFT
HHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEHHHHEECCCCCCCCCCCEEECCCCCCCC
LPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQTLIELGPQVLVQPEDYDIRA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
NLMWVATMALNGTIGVGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLQCTKEAKRE
EEEEEEEEEECCEEECCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHH
KLLQYADRVWHINTGTDDERIDAAIAKTKAFFEAMGIPTHLSAYDLDASHVDTVVKQLEL
HHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHH
HGMVALGEHGNINPAMSRDILTLAL
CCEEEECCCCCCCHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]