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The map label for this gene is hutG

Identifier: 16080989

GI number: 16080989

Start: 4046503

End: 4047462

Strand: Direct

Name: hutG

Synonym: BSU39380

Alternate gene names: 16080989

Gene position: 4046503-4047462 (Clockwise)

Preceding gene: 16080988

Following gene: 255767836

Centisome position: 95.99

GC content: 47.29

Gene sequence:

>960_bases
TTGGATAAGTACCCTTTTCTCAGAGAGGCCGGATCTTCGTTTAAAGACCGGGATGTCACAAAAATGAGCGACCTGATCGC
AACATGGGACGGCCAGGACATTAAGGGACCGGCGTTGATAGGTGTCCCCCTATCAAAATCCTCCATCAGTCATTCAGGCG
CTTCCTTTGCACCCGGAACAATACGCCAGGCTCTGAAACATTCATCAGCCTATTCTGCTGAGCTTGGAGAGCACGTCGTA
TCAGAGCTTCTATATGACCTGGGGGATATCGATATTCATGTCACTGATATCGTAAAGTCACATCATCACATTTTCCAAAC
CATGCACGCTCTGCTTTCGGATCATCCGGATTGGGTGCCGCTCATACTTGGGGGAGATAACTCTATCAGCTACTCCACAA
TAAAAGCGATAGCACAAACAAAAGGAACGACAGCGGTGATTCAATTTGATGCCCATCACGATGTTCGCAATACGGAGGAC
GGGGGGCCGACAAACGGCACCCCCTTCCGCCGCCTTTTGGATGAAGAGATCATTGAAGGTCAACATTTGATCCAGCTGGG
TATCAGAGAATTCAGCAACAGCCAGGCCTATGAAGCATATGCAAAAAAACATAACGTGAACATTCACACGATGGACATGA
TCCGGGAAAAAGGACTAATCCCAACGATAAAAGAGATTTTGCCTGTTGTTCAAGATAAAACAGATTTCATTTTTATATCT
GTTGACATGGATGTCTTAGACCAGTCCCATGCACCCGGCTGTCCAGCGATTGGCCCGGGCGGCCTCTATACAGACGAATT
GCTTGAAGCAGTCAAGTACATCGCACAACAGCCCAATGTTGCCGGGATTGAAATTGTTGAAGTCGACCCTACCCTCGATT
TTCGAGATATGACAAGCAGAGCTGCAGCTCATGTTCTGTTACACGCATTAAAAGGAATGAAACTCTCCCCATTCAAGTGA

Upstream 100 bases:

>100_bases
GCCCCGAACTATATGTATATTCCGTATCACTACGGGGTCAATCATGTACATCAAGTCATGAAAAATGGAACAATTGTTGT
CAACAGGGAGGGAGCCATTC

Downstream 100 bases:

>100_bases
TCTTCTGGCAGGTTGTATTTTGGGTATAAGAAACTCATCTGCCTAAGGAATGGCAGCTAAAAGGAGGGCGAGACAGTGAA
TCTTCAGGAGAACAGCAGCC

Product: formimidoylglutamase

Products: NA

Alternate protein names: Formiminoglutamase; Formiminoglutamate hydrolase

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLSKSSISHSGASFAPGTIRQALKHSSAYSAELGEHVV
SELLYDLGDIDIHVTDIVKSHHHIFQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTED
GGPTNGTPFRRLLDEEIIEGQHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILPVVQDKTDFIFIS
VDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSPFK

Sequences:

>Translated_319_residues
MDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLSKSSISHSGASFAPGTIRQALKHSSAYSAELGEHVV
SELLYDLGDIDIHVTDIVKSHHHIFQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTED
GGPTNGTPFRRLLDEEIIEGQHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILPVVQDKTDFIFIS
VDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSPFK
>Mature_319_residues
MDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLSKSSISHSGASFAPGTIRQALKHSSAYSAELGEHVV
SELLYDLGDIDIHVTDIVKSHHHIFQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTED
GGPTNGTPFRRLLDEEIIEGQHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILPVVQDKTDFIFIS
VDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSPFK

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family

Homologues:

Organism=Homo sapiens, GI37537722, Length=278, Percent_Identity=29.4964028776978, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1789306, Length=268, Percent_Identity=24.2537313432836, Blast_Score=72, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24638886, Length=308, Percent_Identity=24.6753246753247, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTG_BACSU (P42068)

Other databases:

- EMBL:   D31856
- EMBL:   AL009126
- PIR:   B69643
- RefSeq:   NP_391817.1
- PDB:   3M1R
- PDBsum:   3M1R
- ProteinModelPortal:   P42068
- SMR:   P42068
- EnsemblBacteria:   EBBACT00000001847
- GeneID:   937546
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU39380
- NMPDR:   fig|224308.1.peg.3943
- GenoList:   BSU39380
- GeneTree:   EBGT00050000001627
- HOGENOM:   HBG337501
- OMA:   KTIRAML
- ProtClustDB:   PRK01722
- BioCyc:   BSUB:BSU39380-MONOMER
- BioCyc:   MetaCyc:MONOMER-11606
- BRENDA:   3.5.3.8
- HAMAP:   MF_00737
- InterPro:   IPR005923
- InterPro:   IPR006035
- InterPro:   IPR020855
- Gene3D:   G3DSA:3.40.800.10
- PANTHER:   PTHR11358
- PRINTS:   PR00116
- TIGRFAMs:   TIGR01227

Pfam domain/function: PF00491 Arginase

EC number: =3.5.3.8

Molecular weight: Translated: 35064; Mature: 35064

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS01053 ARGINASE_1; PS51409 ARGINASE_2; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLSKSSISHSGASFAPGT
CCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHH
IRQALKHSSAYSAELGEHVVSELLYDLGDIDIHVTDIVKSHHHIFQTMHALLSDHPDWVP
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEE
LILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTEDGGPTNGTPFRRLLDEEIIEG
EEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
QHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILPVVQDKTDFIFIS
HHHHHHHHHHHCCCHHHHHHHHHCCCCEEHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEE
VDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLDFRDMTSR
ECHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHH
AAAHVLLHALKGMKLSPFK
HHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLSKSSISHSGASFAPGT
CCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHH
IRQALKHSSAYSAELGEHVVSELLYDLGDIDIHVTDIVKSHHHIFQTMHALLSDHPDWVP
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEE
LILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTEDGGPTNGTPFRRLLDEEIIEG
EEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
QHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILPVVQDKTDFIFIS
HHHHHHHHHHHCCCHHHHHHHHHCCCCEEHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEE
VDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLDFRDMTSR
ECHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHH
AAAHVLLHALKGMKLSPFK
HHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704263; 9384377