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The map label for this gene is yxkI

Identifier: 16080929

GI number: 16080929

Start: 3981227

End: 3982915

Strand: Direct

Name: yxkI

Synonym: BSU38780

Alternate gene names: 16080929

Gene position: 3981227-3982915 (Clockwise)

Preceding gene: 16080928

Following gene: 16080930

Centisome position: 94.44

GC content: 46.06

Gene sequence:

>1689_bases
ATGCCTATGGGAACTCATCTATTTCTCTTTATGCTTCTCGGGCTGGGATTTTATTTGATATCAGCCCTAGCTGCAAAACT
CATTCCGGCCATAGACTTCTGGATTGATATTGTTCTATGGGTCGGCGCTGCGGCTTACATCTTCTCTCATCTCTCATTCA
TGGACGGCATTGTCTCACTCGCGACAATGTTCTACTGCTATTGGACCGCAATGGATCTCATTGTTTCAGAGCGTGTGGAA
AAACCTTCGGGAGACTGGCAGGAAATCGAGCTTGCCAAAAACAAAACACGCCTCCTGTCAGACATTACGCTGACCGCCAT
TGTGTTTGCAGGGGCTGTCATTTTTTTCATCTATGGACCTGACACAAGCCCTCTCAAATATGTGATCCTTCTCGGAATGA
TCTCCGGCGGAGGGGCACTTGTGAAGCGAATACTGAATGTTTTTAGCGTAAAGGTTTTTTATTCAGCAGCCTTAGAAAAA
TTGCATATCAGCTCACACTATGAAACCCGTACATACCCGCTTTCCGATTTGAAGAACATTCAGCTTGAATCAACAGCAGA
TCTCTTAAAGCTCCATCCGCTTCTGACGATGTATTCATCCCGTTTAGATTTGACAACAAGCTTTCAGCAAGTCATTAAAC
TGTCTCTTCCCGGCGAAACACTGTTTCTGACGGTGAAGGAACCGCAAAAATGGAAAACAATTCTTCAGGAATACACAGAT
GCAGAAAACAATGTGGACAATGTGATTTCTGTTTTGCCGTTTTATCATCGAAAAAATGTGAAGCGGCTGCTCGGTAAGCT
TTATTTTGCCGCCAGCGTAAAAGGGGTATCCGCTTACGCCTTATTGGTGCTCGCGTTATACGCATTACACGCCTCTCCAT
GGGTCATGGCTGTTGCCGTAATCCTATATTGGGTATTCAACATGTATATGTCAGACCGTGTGTTGCGGGCGGCGATGGAC
GCCAAGTCTTGTCATCATCCGCATGTACAGGCCGCGGCCGATAAGATTTTCAGATCGGCCGGCATTTCCCATGTCCGCAT
ATACGAAACGGAGAGTGATGATTACAACGGAATGGCAGTAGGCATGAATGTCGGGAGGTCAATGGTCATCCTGACAAGCG
CCACACTAACACTTCCACAGCGTGTCATTGAAGGCATTCTGGCCCATGAGGCGATTCATATCAAAAAACGTGACGTTCTG
TCATCACAGCTTTTGCGTTTTCTATATCTTGGAGCTGTCGTGGGGATTTTCCTCTTGTTTGAGCAGCATATCACCCATCC
CGAGGCCCACAAAATTGCGCTTTGGGCTTTCATTATGGCAATCATTATCCTATTCCAGCTCTATCAATCCTTTTGTTCAC
AATGGATGGAGGTGCGTGCTGACAACCTTGGCGCATCATTGCTGGACGGCGGTTACAAACAAATGGCTGAAGCCTTGAGA
ATCTTGGCGGTTCGGCAAGATGAGGATATACAGAAACAAAGTGCCTATAGCTCTGAAGCAGGTGAAGACGAGCTTCAAAT
TGATTCTCTCACCCGTGATAAAAGCTGGTTTTTCAGATTGATTGATTTTCAGTTCGCTCCTCATCCTCCTATGTATTGGC
GTGTCGGCACTTTATTGTCAAACAAAGGACATGGGGTGCTAAAGCGCTGGCTCAGAGACCGACTGAAAGAATCGATCACT
TTGAAATGA

Upstream 100 bases:

>100_bases
TCAAACGAAAGAGCTTGCTTTTTTGCATGTCCATGTTTTTGCAAGTTCCCATCCCATGCTATAGTAATAGTTGGAAATAC
TAGATAGAAAGGAATCTGGC

Downstream 100 bases:

>100_bases
AACCGGTCAGCGTTTCATCCGTATAACAGATATGGTGAAAAAAGGGAGTGACGCGAAGTGATTGTGATCATCTTATTGTT
TATATCTATTATTGTTTTTC

Product: membrane protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MPMGTHLFLFMLLGLGFYLISALAAKLIPAIDFWIDIVLWVGAAAYIFSHLSFMDGIVSLATMFYCYWTAMDLIVSERVE
KPSGDWQEIELAKNKTRLLSDITLTAIVFAGAVIFFIYGPDTSPLKYVILLGMISGGGALVKRILNVFSVKVFYSAALEK
LHISSHYETRTYPLSDLKNIQLESTADLLKLHPLLTMYSSRLDLTTSFQQVIKLSLPGETLFLTVKEPQKWKTILQEYTD
AENNVDNVISVLPFYHRKNVKRLLGKLYFAASVKGVSAYALLVLALYALHASPWVMAVAVILYWVFNMYMSDRVLRAAMD
AKSCHHPHVQAAADKIFRSAGISHVRIYETESDDYNGMAVGMNVGRSMVILTSATLTLPQRVIEGILAHEAIHIKKRDVL
SSQLLRFLYLGAVVGIFLLFEQHITHPEAHKIALWAFIMAIIILFQLYQSFCSQWMEVRADNLGASLLDGGYKQMAEALR
ILAVRQDEDIQKQSAYSSEAGEDELQIDSLTRDKSWFFRLIDFQFAPHPPMYWRVGTLLSNKGHGVLKRWLRDRLKESIT
LK

Sequences:

>Translated_562_residues
MPMGTHLFLFMLLGLGFYLISALAAKLIPAIDFWIDIVLWVGAAAYIFSHLSFMDGIVSLATMFYCYWTAMDLIVSERVE
KPSGDWQEIELAKNKTRLLSDITLTAIVFAGAVIFFIYGPDTSPLKYVILLGMISGGGALVKRILNVFSVKVFYSAALEK
LHISSHYETRTYPLSDLKNIQLESTADLLKLHPLLTMYSSRLDLTTSFQQVIKLSLPGETLFLTVKEPQKWKTILQEYTD
AENNVDNVISVLPFYHRKNVKRLLGKLYFAASVKGVSAYALLVLALYALHASPWVMAVAVILYWVFNMYMSDRVLRAAMD
AKSCHHPHVQAAADKIFRSAGISHVRIYETESDDYNGMAVGMNVGRSMVILTSATLTLPQRVIEGILAHEAIHIKKRDVL
SSQLLRFLYLGAVVGIFLLFEQHITHPEAHKIALWAFIMAIIILFQLYQSFCSQWMEVRADNLGASLLDGGYKQMAEALR
ILAVRQDEDIQKQSAYSSEAGEDELQIDSLTRDKSWFFRLIDFQFAPHPPMYWRVGTLLSNKGHGVLKRWLRDRLKESIT
LK
>Mature_561_residues
PMGTHLFLFMLLGLGFYLISALAAKLIPAIDFWIDIVLWVGAAAYIFSHLSFMDGIVSLATMFYCYWTAMDLIVSERVEK
PSGDWQEIELAKNKTRLLSDITLTAIVFAGAVIFFIYGPDTSPLKYVILLGMISGGGALVKRILNVFSVKVFYSAALEKL
HISSHYETRTYPLSDLKNIQLESTADLLKLHPLLTMYSSRLDLTTSFQQVIKLSLPGETLFLTVKEPQKWKTILQEYTDA
ENNVDNVISVLPFYHRKNVKRLLGKLYFAASVKGVSAYALLVLALYALHASPWVMAVAVILYWVFNMYMSDRVLRAAMDA
KSCHHPHVQAAADKIFRSAGISHVRIYETESDDYNGMAVGMNVGRSMVILTSATLTLPQRVIEGILAHEAIHIKKRDVLS
SQLLRFLYLGAVVGIFLLFEQHITHPEAHKIALWAFIMAIIILFQLYQSFCSQWMEVRADNLGASLLDGGYKQMAEALRI
LAVRQDEDIQKQSAYSSEAGEDELQIDSLTRDKSWFFRLIDFQFAPHPPMYWRVGTLLSNKGHGVLKRWLRDRLKESITL
K

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YXKI_BACSU (P94362)

Other databases:

- EMBL:   D83026
- EMBL:   AL009126
- PIR:   B70081
- RefSeq:   NP_391757.1
- ProteinModelPortal:   P94362
- SMR:   P94362
- EnsemblBacteria:   EBBACT00000003242
- GeneID:   937415
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38780
- NMPDR:   fig|224308.1.peg.3883
- GenoList:   BSU38780
- HOGENOM:   HBG491328
- OMA:   EGILAHE
- ProtClustDB:   CLSK626748
- BioCyc:   BSUB:BSU38780-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001915

Pfam domain/function: PF01435 Peptidase_M48

EC number: NA

Molecular weight: Translated: 63612; Mature: 63481

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 390-390

Signals:

None

Transmembrane regions:

HASH(0x1335e054)-; HASH(0x13625984)-; HASH(0x12d90fa4)-; HASH(0x12378114)-; HASH(0x13082b98)-; HASH(0x1346cfe4)-; HASH(0x10bebe40)-; HASH(0xe9528d8)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMGTHLFLFMLLGLGFYLISALAAKLIPAIDFWIDIVLWVGAAAYIFSHLSFMDGIVSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATMFYCYWTAMDLIVSERVEKPSGDWQEIELAKNKTRLLSDITLTAIVFAGAVIFFIYGP
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
DTSPLKYVILLGMISGGGALVKRILNVFSVKVFYSAALEKLHISSHYETRTYPLSDLKNI
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCC
QLESTADLLKLHPLLTMYSSRLDLTTSFQQVIKLSLPGETLFLTVKEPQKWKTILQEYTD
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
AENNVDNVISVLPFYHRKNVKRLLGKLYFAASVKGVSAYALLVLALYALHASPWVMAVAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHH
ILYWVFNMYMSDRVLRAAMDAKSCHHPHVQAAADKIFRSAGISHVRIYETESDDYNGMAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEE
GMNVGRSMVILTSATLTLPQRVIEGILAHEAIHIKKRDVLSSQLLRFLYLGAVVGIFLLF
ECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQHITHPEAHKIALWAFIMAIIILFQLYQSFCSQWMEVRADNLGASLLDGGYKQMAEALR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHH
ILAVRQDEDIQKQSAYSSEAGEDELQIDSLTRDKSWFFRLIDFQFAPHPPMYWRVGTLLS
HHHHCCCCHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEHHHHHC
NKGHGVLKRWLRDRLKESITLK
CCCCHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
PMGTHLFLFMLLGLGFYLISALAAKLIPAIDFWIDIVLWVGAAAYIFSHLSFMDGIVSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATMFYCYWTAMDLIVSERVEKPSGDWQEIELAKNKTRLLSDITLTAIVFAGAVIFFIYGP
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
DTSPLKYVILLGMISGGGALVKRILNVFSVKVFYSAALEKLHISSHYETRTYPLSDLKNI
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCC
QLESTADLLKLHPLLTMYSSRLDLTTSFQQVIKLSLPGETLFLTVKEPQKWKTILQEYTD
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
AENNVDNVISVLPFYHRKNVKRLLGKLYFAASVKGVSAYALLVLALYALHASPWVMAVAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHH
ILYWVFNMYMSDRVLRAAMDAKSCHHPHVQAAADKIFRSAGISHVRIYETESDDYNGMAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEE
GMNVGRSMVILTSATLTLPQRVIEGILAHEAIHIKKRDVLSSQLLRFLYLGAVVGIFLLF
ECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQHITHPEAHKIALWAFIMAIIILFQLYQSFCSQWMEVRADNLGASLLDGGYKQMAEALR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHH
ILAVRQDEDIQKQSAYSSEAGEDELQIDSLTRDKSWFFRLIDFQFAPHPPMYWRVGTLLS
HHHHCCCCHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEHHHHHC
NKGHGVLKRWLRDRLKESITLK
CCCCHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377