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The map label for this gene is yxlA

Identifier: 16080922

GI number: 16080922

Start: 3971060

End: 3972433

Strand: Direct

Name: yxlA

Synonym: BSU38710

Alternate gene names: 16080922

Gene position: 3971060-3972433 (Clockwise)

Preceding gene: 16080915

Following gene: 16080928

Centisome position: 94.2

GC content: 45.49

Gene sequence:

>1374_bases
TTGAAAGTAGAAAGGCGAACGATTGAATATATTCCGAATGAAGAAAGACATGGTAAAGCGAAAGATTTATTTCCCGTATG
GTTCGGGGCTAATATGCATATCACCACGTTAGTGACCGGCACGATTCCCGTTGCAATGGGACTTAATCTGTTTTGGAGTG
TTGCCGCTATTATTTGCGGAACCTTAATCGGTGCCATATTTATGGCTTCTCATTCCGCGCAAGGCCCTCAGCTAGGCATC
CCGCAAATGATTCAAAGCCGTGCCCAATTCGGCGTAATCGGAGCGATTCTTCCCCTCTTCTTAGTCATGTTTATCTACCT
TGGTTTCTTCGCAAGCAGCACGATTCTGGCGGCCGGAACCTTAAGCAGCTTTGTTCCCATCCCGGGATCATGGAGCATTA
TAGGCTTAAGTGCCGTATGTTTTTTACTCACCATTTTCGGCCATGATTTGATTCACAAAATGCAAAAAATCCTTTCTTGG
ACCTCTTTTGCTGTATTTTTTGCTGCAACGATTCTCATTTTTCAATTGCCGATTCCGGCAGGCAGCTGGATACCCGGAGC
GATTGATCTGCCAATTTTCCTAGTGGCAGTCAGCGCAGTTGCGACGTGGCAGCTTGCCTACGCGCCGTATGTTGCCGATT
ATTCAAGATATCTGCCAGTTAAAACACCGGCTTCAAAAACATTTTGGTACAGCTATGCAGGTACATCTGTCAGCTCCATC
TGGATGATGCTGCTCGGCGCATTGCTGACAACCTCACTTCCTGACTTTACGGCAAACTCAGGCAGCCAGATTGTCCAATT
GTTCGGTCCCTTCTCGTTTATTATGCTGATCATTGTGCTATTTGGGCAAATGGCAATCAATGTTTTTAACCTGTATGGGG
CTTTCATGTCCACGACAACAACGCTGGAGCCGTTTCTGAAATTAAAAGTCACGCCCAAAGTCAGAATCATCATGATCCTG
GGTGTCACGCTTGTCGGCACAGTCTTAAGCCTACTGGGACAGAGCAATTTTATGGAACTGTTTTTGAATTTTATCTTTTT
CATCAGTTATTTCTTAATTCCGTGGACGGCAATCAATTTAGTCGATTACTACTTCGTCCGCCACGGAAAGTATCAAGTCA
AAGCCATGTTCGACGTAAACGGGCCTTATGGAAAGGTCAATTGGATCACCACAATTGCGTTCGTTCTGTCTATCTTGCTG
GAAATTCCGTTTATCAACACAAGCTTTTACATCGGACCGCTTGCCAAAATGTTTGGCGGCGGAGACATCGCATGGATTAT
CGGCTTGGCCGTGCCTTCTGTGCTTTACTATGTATTAATGAAACCGCGTCTGAAAAAACGGGCGGGGTATCAAGAAAAGC
TGTCTTCTCTCTGA

Upstream 100 bases:

>100_bases
CCGTTTGGCTGCATATCCTTATTTGTAAACCCCCTTATAGTCTGTTAAGCTATGACTTTATGTCGATTTCAAAAAAACAT
CCAATATGGAGGACGATGCA

Downstream 100 bases:

>100_bases
AGACAGCTTTTTTATCATTCAAATCGTTTCCACACGCGGGGCAGGATGTCAGATAGCTCATGAGCGAGCAACGTATGAGC
GGAGTGCTCGTCCGTCCAGA

Product: purine-cytosine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKVERRTIEYIPNEERHGKAKDLFPVWFGANMHITTLVTGTIPVAMGLNLFWSVAAIICGTLIGAIFMASHSAQGPQLGI
PQMIQSRAQFGVIGAILPLFLVMFIYLGFFASSTILAAGTLSSFVPIPGSWSIIGLSAVCFLLTIFGHDLIHKMQKILSW
TSFAVFFAATILIFQLPIPAGSWIPGAIDLPIFLVAVSAVATWQLAYAPYVADYSRYLPVKTPASKTFWYSYAGTSVSSI
WMMLLGALLTTSLPDFTANSGSQIVQLFGPFSFIMLIIVLFGQMAINVFNLYGAFMSTTTTLEPFLKLKVTPKVRIIMIL
GVTLVGTVLSLLGQSNFMELFLNFIFFISYFLIPWTAINLVDYYFVRHGKYQVKAMFDVNGPYGKVNWITTIAFVLSILL
EIPFINTSFYIGPLAKMFGGGDIAWIIGLAVPSVLYYVLMKPRLKKRAGYQEKLSSL

Sequences:

>Translated_457_residues
MKVERRTIEYIPNEERHGKAKDLFPVWFGANMHITTLVTGTIPVAMGLNLFWSVAAIICGTLIGAIFMASHSAQGPQLGI
PQMIQSRAQFGVIGAILPLFLVMFIYLGFFASSTILAAGTLSSFVPIPGSWSIIGLSAVCFLLTIFGHDLIHKMQKILSW
TSFAVFFAATILIFQLPIPAGSWIPGAIDLPIFLVAVSAVATWQLAYAPYVADYSRYLPVKTPASKTFWYSYAGTSVSSI
WMMLLGALLTTSLPDFTANSGSQIVQLFGPFSFIMLIIVLFGQMAINVFNLYGAFMSTTTTLEPFLKLKVTPKVRIIMIL
GVTLVGTVLSLLGQSNFMELFLNFIFFISYFLIPWTAINLVDYYFVRHGKYQVKAMFDVNGPYGKVNWITTIAFVLSILL
EIPFINTSFYIGPLAKMFGGGDIAWIIGLAVPSVLYYVLMKPRLKKRAGYQEKLSSL
>Mature_457_residues
MKVERRTIEYIPNEERHGKAKDLFPVWFGANMHITTLVTGTIPVAMGLNLFWSVAAIICGTLIGAIFMASHSAQGPQLGI
PQMIQSRAQFGVIGAILPLFLVMFIYLGFFASSTILAAGTLSSFVPIPGSWSIIGLSAVCFLLTIFGHDLIHKMQKILSW
TSFAVFFAATILIFQLPIPAGSWIPGAIDLPIFLVAVSAVATWQLAYAPYVADYSRYLPVKTPASKTFWYSYAGTSVSSI
WMMLLGALLTTSLPDFTANSGSQIVQLFGPFSFIMLIIVLFGQMAINVFNLYGAFMSTTTTLEPFLKLKVTPKVRIIMIL
GVTLVGTVLSLLGQSNFMELFLNFIFFISYFLIPWTAINLVDYYFVRHGKYQVKAMFDVNGPYGKVNWITTIAFVLSILL
EIPFINTSFYIGPLAKMFGGGDIAWIIGLAVPSVLYYVLMKPRLKKRAGYQEKLSSL

Specific function: Unknown

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family

Homologues:

Organism=Saccharomyces cerevisiae, GI6320897, Length=479, Percent_Identity=25.678496868476, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320902, Length=480, Percent_Identity=25.625, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320903, Length=477, Percent_Identity=25.5765199161426, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YXLA_BACSU (P94369)

Other databases:

- EMBL:   D83026
- EMBL:   AL009126
- PIR:   E70081
- RefSeq:   NP_391750.1
- ProteinModelPortal:   P94369
- EnsemblBacteria:   EBBACT00000002002
- GeneID:   937405
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38710
- NMPDR:   fig|224308.1.peg.3876
- GenoList:   BSU38710
- GeneTree:   EBGT00070000032308
- HOGENOM:   HBG289436
- OMA:   RVQFGVY
- PhylomeDB:   P94369
- ProtClustDB:   CLSK2752561
- BioCyc:   BSUB:BSU38710-MONOMER
- InterPro:   IPR001248

Pfam domain/function: PF02133 Transp_cyt_pur

EC number: NA

Molecular weight: Translated: 50518; Mature: 50518

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x133cac28)-; HASH(0x120c6054)-; HASH(0x137cb684)-; HASH(0x12f4ea9c)-; HASH(0x1258da8c)-; HASH(0x1338f348)-; HASH(0x12f3d918)-; HASH(0x1349b1d4)-; HASH(0x12d9bab4)-; HASH(0x12eda728)-; HASH(0x1343d2fc)-; HASH(0x12bf8544)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVERRTIEYIPNEERHGKAKDLFPVWFGANMHITTLVTGTIPVAMGLNLFWSVAAIICG
CCCCCCHHHCCCCCCCCCCCCCCCEEEECCCEEEEEEEECHHHHHHHHHHHHHHHHHHHH
TLIGAIFMASHSAQGPQLGIPQMIQSRAQFGVIGAILPLFLVMFIYLGFFASSTILAAGT
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSFVPIPGSWSIIGLSAVCFLLTIFGHDLIHKMQKILSWTSFAVFFAATILIFQLPIPA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GSWIPGAIDLPIFLVAVSAVATWQLAYAPYVADYSRYLPVKTPASKTFWYSYAGTSVSSI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHH
WMMLLGALLTTSLPDFTANSGSQIVQLFGPFSFIMLIIVLFGQMAINVFNLYGAFMSTTT
HHHHHHHHHHCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLEPFLKLKVTPKVRIIMILGVTLVGTVLSLLGQSNFMELFLNFIFFISYFLIPWTAINL
HHHHHHEEEECCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VDYYFVRHGKYQVKAMFDVNGPYGKVNWITTIAFVLSILLEIPFINTSFYIGPLAKMFGG
HHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
GDIAWIIGLAVPSVLYYVLMKPRLKKRAGYQEKLSSL
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHCH
>Mature Secondary Structure
MKVERRTIEYIPNEERHGKAKDLFPVWFGANMHITTLVTGTIPVAMGLNLFWSVAAIICG
CCCCCCHHHCCCCCCCCCCCCCCCEEEECCCEEEEEEEECHHHHHHHHHHHHHHHHHHHH
TLIGAIFMASHSAQGPQLGIPQMIQSRAQFGVIGAILPLFLVMFIYLGFFASSTILAAGT
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSFVPIPGSWSIIGLSAVCFLLTIFGHDLIHKMQKILSWTSFAVFFAATILIFQLPIPA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GSWIPGAIDLPIFLVAVSAVATWQLAYAPYVADYSRYLPVKTPASKTFWYSYAGTSVSSI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHH
WMMLLGALLTTSLPDFTANSGSQIVQLFGPFSFIMLIIVLFGQMAINVFNLYGAFMSTTT
HHHHHHHHHHCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLEPFLKLKVTPKVRIIMILGVTLVGTVLSLLGQSNFMELFLNFIFFISYFLIPWTAINL
HHHHHHEEEECCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VDYYFVRHGKYQVKAMFDVNGPYGKVNWITTIAFVLSILLEIPFINTSFYIGPLAKMFGG
HHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
GDIAWIIGLAVPSVLYYVLMKPRLKKRAGYQEKLSSL
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377